UT Health San Antonio researchers engineered U-report, a CBE/AMBER biosensor that quantifies live-cell chromosomal UNG activity in real time, revealing that mitochondrial UNG1 actively participates in nuclear uracil repair. 🧬🤖 #DNArepair #Ureport #BaseEditing #GenomicStability #Epigenetics

Earlier this week, CSI Singapore hosted Prof. Jayanta Chaudhuri from @mskcancercenter.bsky.social. He spoke on the topic “Elucidation of Factors Enforcing Genomic Stability and Lineage Stability in B Cells”.

#genomicstability #bcellbiology #cancerimmunology #immunology #immunogenomics

🧬 Don't miss the fourth and final session of NAR Cancer's 5th Anniversary Virtual Symposium!

🕛 Thursday 17 April at 12pm US Eastern time

👥 Speakers include Dr Elise Fouquerel and Dr Robert W. Sobol

Register here: lnkd.in/eRxxSxeu

#NARCancer #PARPInhibitors #DNARepair #GenomicStability

🧬 Don't miss the 4th session of NAR Cancer's 5th Anniversary Virtual Symposium!

🕛 Thursday 17 April - 12pm US Eastern time

👥 Featuring Dr Elise Fouquerel and Dr Robert W. Sobol

👉 Register here: lnkd.in/eRxxSxeu

#NARCancer #CancerResearch #DNADamage #DNARepair #GenomicStability #PARPInhibitors

KAT2A-mediated #succinylation of the #splicingfactor SRSF11 at K419 enhances #DNARepair and #radioresistance in #HCC by promoting RAD52 exon inclusion, linking #AlternativeSplicing to #GenomicStability and offering a potential therapeutic target.

#STTT: doi.org/10.1038/s413...