www.frontiersin.org/journals/cel... New paper from our lab demonstrating that secondary neurulation likely arose in vertebrates to enable mesenchymal tailbud extension.
September 25, 2026 at 10:35 AM
www.frontiersin.org/journals/cel... New paper from our lab demonstrating that secondary neurulation likely arose in vertebrates to enable mesenchymal tailbud extension.
Happy birthday tailbud! 🥳
September 4, 2026 at 6:45 AM
Happy birthday tailbud! 🥳
#DBfeature #ICYMI 🐸
Identification, expression and function of 28 new candidate regulators of placodal neurogenesis in Xenopus laevis
By Bertrand Hutlet, Gerhard Schlosser
tinyurl.com/34szsky6
Identification, expression and function of 28 new candidate regulators of placodal neurogenesis in Xenopus laevis
By Bertrand Hutlet, Gerhard Schlosser
tinyurl.com/34szsky6
July 23, 2026 at 2:31 PM
#DBfeature #ICYMI 🐸
Identification, expression and function of 28 new candidate regulators of placodal neurogenesis in Xenopus laevis
By Bertrand Hutlet, Gerhard Schlosser
tinyurl.com/34szsky6
Identification, expression and function of 28 new candidate regulators of placodal neurogenesis in Xenopus laevis
By Bertrand Hutlet, Gerhard Schlosser
tinyurl.com/34szsky6
TAILBUD INFERRED
July 23, 2026 at 5:19 AM
TAILBUD INFERRED
AND YOU MAY FIND YOURSELF CIRCUMSCRIBING NEAR A SPATTERED TAILBUD
July 12, 2026 at 12:55 AM
AND YOU MAY FIND YOURSELF CIRCUMSCRIBING NEAR A SPATTERED TAILBUD
Your sad outlay scarifies cummerbund, and dressily evasively fairies. Vulgarly sublicence one of everybody's tailbud llamas conceitedly.
July 9, 2026 at 1:58 PM
Your sad outlay scarifies cummerbund, and dressily evasively fairies. Vulgarly sublicence one of everybody's tailbud llamas conceitedly.
Knock knock!
>Who's there?
Tailbud
>Tailbud who?
Potty pee diarrhea booger diaper doo-doo!
>Who's there?
Tailbud
>Tailbud who?
Potty pee diarrhea booger diaper doo-doo!
July 8, 2026 at 3:14 PM
Knock knock!
>Who's there?
Tailbud
>Tailbud who?
Potty pee diarrhea booger diaper doo-doo!
>Who's there?
Tailbud
>Tailbud who?
Potty pee diarrhea booger diaper doo-doo!
his tailbud is closed by default, but the bloom opens when he is threatened. when open it gives off a heady, intoxicating scent that can daze enemies.
want more info about his species? go here ➡️ erraticstatic.dreamwidth.org/1535.html
want more info about his species? go here ➡️ erraticstatic.dreamwidth.org/1535.html
June 25, 2026 at 4:22 AM
his tailbud is closed by default, but the bloom opens when he is threatened. when open it gives off a heady, intoxicating scent that can daze enemies.
want more info about his species? go here ➡️ erraticstatic.dreamwidth.org/1535.html
want more info about his species? go here ➡️ erraticstatic.dreamwidth.org/1535.html
Hey Anahi...nice work !
Segments are normal sized, so is overall segment number and axis length (when tailbud is amputated).
I do think this is an eel-specific feature since the distribution of NMPs is quite unique and the pools are utilized differently over somitogensis.
Segments are normal sized, so is overall segment number and axis length (when tailbud is amputated).
I do think this is an eel-specific feature since the distribution of NMPs is quite unique and the pools are utilized differently over somitogensis.
May 25, 2026 at 11:48 AM
Hey Anahi...nice work !
Segments are normal sized, so is overall segment number and axis length (when tailbud is amputated).
I do think this is an eel-specific feature since the distribution of NMPs is quite unique and the pools are utilized differently over somitogensis.
Segments are normal sized, so is overall segment number and axis length (when tailbud is amputated).
I do think this is an eel-specific feature since the distribution of NMPs is quite unique and the pools are utilized differently over somitogensis.
I see ! It is interesting that regeneration is (yet another) module that is dissociable from development.
In eels we do not find evidence of regeneration at any stage if the whole PSM is amputated but they are able to continue segmenting after tailbud amputation (likely using their rostral NMPs)
In eels we do not find evidence of regeneration at any stage if the whole PSM is amputated but they are able to continue segmenting after tailbud amputation (likely using their rostral NMPs)
May 24, 2026 at 4:27 PM
I see ! It is interesting that regeneration is (yet another) module that is dissociable from development.
In eels we do not find evidence of regeneration at any stage if the whole PSM is amputated but they are able to continue segmenting after tailbud amputation (likely using their rostral NMPs)
In eels we do not find evidence of regeneration at any stage if the whole PSM is amputated but they are able to continue segmenting after tailbud amputation (likely using their rostral NMPs)
Nice work Wouter and team !
Just a methodological question when you amputate the tailbud you mean the whole unsegmented PSM until the last formed somite correct ?
Just a methodological question when you amputate the tailbud you mean the whole unsegmented PSM until the last formed somite correct ?
May 24, 2026 at 1:44 PM
Nice work Wouter and team !
Just a methodological question when you amputate the tailbud you mean the whole unsegmented PSM until the last formed somite correct ?
Just a methodological question when you amputate the tailbud you mean the whole unsegmented PSM until the last formed somite correct ?
Really beautiful work Ali, lots of inspiring findings! Here we had thought (for amphioxus) even a tailbud gradient may be dispensible for sequential segmentation: febs.onlinelibrary.wiley.com/doi/10.1111/... Do you think eels carry a posterior gradient despite their horseshoe shaped signal center?
FEBS Press
Sequential segmentation is widespread among organisms from plants to basal chordates and humans. Three prerequisites can be proposed for sequentially segmenting species: first, presence of a cell sig....
share.google
May 10, 2026 at 3:41 PM
Really beautiful work Ali, lots of inspiring findings! Here we had thought (for amphioxus) even a tailbud gradient may be dispensible for sequential segmentation: febs.onlinelibrary.wiley.com/doi/10.1111/... Do you think eels carry a posterior gradient despite their horseshoe shaped signal center?
Second: Germ layer fate restriction begins before gastrulation and extends beyond it. Detectable germ layer bias in the epiblast first appears ~E4. By contrast, in the growing tailbud bipotent axial progenitors continue to specify additional mesoderm and ectoderm through E9.5
May 9, 2026 at 4:25 PM
Second: Germ layer fate restriction begins before gastrulation and extends beyond it. Detectable germ layer bias in the epiblast first appears ~E4. By contrast, in the growing tailbud bipotent axial progenitors continue to specify additional mesoderm and ectoderm through E9.5
What did we find? We dissected fate restriction across the developing notochord, heart, neural crest, and tailbud. From these case studies, a few high-level principles about mammalian development emerged
May 9, 2026 at 4:25 PM
What did we find? We dissected fate restriction across the developing notochord, heart, neural crest, and tailbud. From these case studies, a few high-level principles about mammalian development emerged
(11/15)
In every vertebrate studied to date, neuromesodermal progenitors (NMPs) — the bipotent stem cells that sustain axis segmentation — exist as a single tailbud pool.
In eels, we discover TWO spatially distinct NMP pools.
Microsurgical amputations show eels segment even without a tailbud !
In every vertebrate studied to date, neuromesodermal progenitors (NMPs) — the bipotent stem cells that sustain axis segmentation — exist as a single tailbud pool.
In eels, we discover TWO spatially distinct NMP pools.
Microsurgical amputations show eels segment even without a tailbud !
May 5, 2026 at 11:41 AM
(11/15)
In every vertebrate studied to date, neuromesodermal progenitors (NMPs) — the bipotent stem cells that sustain axis segmentation — exist as a single tailbud pool.
In eels, we discover TWO spatially distinct NMP pools.
Microsurgical amputations show eels segment even without a tailbud !
In every vertebrate studied to date, neuromesodermal progenitors (NMPs) — the bipotent stem cells that sustain axis segmentation — exist as a single tailbud pool.
In eels, we discover TWO spatially distinct NMP pools.
Microsurgical amputations show eels segment even without a tailbud !
Dech's tail usually entices smaller creatures like rats and birds with its pheromones. Certain individuals prove surprisingly susceptible to it, though, like Sehiny here! But hey, surely there's no worries for a draco-lich in a creature that eats magic, too, right?
Art by Arkail, featuring Sehiny!
Art by Arkail, featuring Sehiny!
April 28, 2026 at 5:15 PM
Dech's tail usually entices smaller creatures like rats and birds with its pheromones. Certain individuals prove surprisingly susceptible to it, though, like Sehiny here! But hey, surely there's no worries for a draco-lich in a creature that eats magic, too, right?
Art by Arkail, featuring Sehiny!
Art by Arkail, featuring Sehiny!
Dech's tail usually entices smaller creatures like rats and birds with its pheromones. Certain individuals prove surprisingly susceptible to it, though, like Sehiny here! But hey, surely there's no worries for a draco-lich in a creature that eats magic, too, right?
Art by Arkail, featuring Sehiny!
Art by Arkail, featuring Sehiny!
April 28, 2026 at 5:00 PM
Dech's tail usually entices smaller creatures like rats and birds with its pheromones. Certain individuals prove surprisingly susceptible to it, though, like Sehiny here! But hey, surely there's no worries for a draco-lich in a creature that eats magic, too, right?
Art by Arkail, featuring Sehiny!
Art by Arkail, featuring Sehiny!
Looking for a #post-doc?
#MSCA-PF 2026 program @sorbonne-universite.fr
The #DEEVA team of @biom-banyuls.bsky.social from @obs-banyuls.fr in #WindyBanyuls from @sorbonne-universite.fr and @cnrsoccitanieest.bsky.social proposes a research project on #ascidians to host a post-doctoral fellow.
#MSCA-PF 2026 program @sorbonne-universite.fr
The #DEEVA team of @biom-banyuls.bsky.social from @obs-banyuls.fr in #WindyBanyuls from @sorbonne-universite.fr and @cnrsoccitanieest.bsky.social proposes a research project on #ascidians to host a post-doctoral fellow.
March 5, 2026 at 5:02 PM
Looking for a #post-doc?
#MSCA-PF 2026 program @sorbonne-universite.fr
The #DEEVA team of @biom-banyuls.bsky.social from @obs-banyuls.fr in #WindyBanyuls from @sorbonne-universite.fr and @cnrsoccitanieest.bsky.social proposes a research project on #ascidians to host a post-doctoral fellow.
#MSCA-PF 2026 program @sorbonne-universite.fr
The #DEEVA team of @biom-banyuls.bsky.social from @obs-banyuls.fr in #WindyBanyuls from @sorbonne-universite.fr and @cnrsoccitanieest.bsky.social proposes a research project on #ascidians to host a post-doctoral fellow.
Happy #FluorescenceFriday Here's a collage of some of my favorite images from my postdoc. See alt for descriptions. 🧪 🐸 #retina
February 20, 2026 at 7:05 PM
Happy #FluorescenceFriday Here's a collage of some of my favorite images from my postdoc. See alt for descriptions. 🧪 🐸 #retina
YOU MAY FIND YOURSELF OVERSTIMULATING IN A LIFELESS TAILBUD
February 14, 2026 at 12:30 AM
YOU MAY FIND YOURSELF OVERSTIMULATING IN A LIFELESS TAILBUD
Bon appétit les LoulouX 😄
Ayeeeeee 😃 C'est le week-end 🤩 Je vais rejoindre @MrSirban.bsky.social à la maison pour le déjeuner 😋 Il a encore le télétravail cet après-midi 😬La vidéo n'est pas du jour ☺️
BisouxXx grisaille 😘
🆓👉 amantelilli.com
#ButtPlugFriday #rosebud #tailbud
Ayeeeeee 😃 C'est le week-end 🤩 Je vais rejoindre @MrSirban.bsky.social à la maison pour le déjeuner 😋 Il a encore le télétravail cet après-midi 😬La vidéo n'est pas du jour ☺️
BisouxXx grisaille 😘
🆓👉 amantelilli.com
#ButtPlugFriday #rosebud #tailbud
February 13, 2026 at 11:21 AM
Bon appétit les LoulouX 😄
Ayeeeeee 😃 C'est le week-end 🤩 Je vais rejoindre @MrSirban.bsky.social à la maison pour le déjeuner 😋 Il a encore le télétravail cet après-midi 😬La vidéo n'est pas du jour ☺️
BisouxXx grisaille 😘
🆓👉 amantelilli.com
#ButtPlugFriday #rosebud #tailbud
Ayeeeeee 😃 C'est le week-end 🤩 Je vais rejoindre @MrSirban.bsky.social à la maison pour le déjeuner 😋 Il a encore le télétravail cet après-midi 😬La vidéo n'est pas du jour ☺️
BisouxXx grisaille 😘
🆓👉 amantelilli.com
#ButtPlugFriday #rosebud #tailbud
[Anal] Tailbud, le rosebud queue de cheval amantelilli.com/plug-queue-c...
Hennir de plaisir avec le rosebud tailbud | AmanteLilli
Le plug anal queue de cheval, un rosebud tailbud d'un érotisme fou et d'une sensualité presque animale ! Pour hennir de plaisir en mode "ponygirl".
amantelilli.com
February 12, 2026 at 8:46 PM
[Anal] Tailbud, le rosebud queue de cheval amantelilli.com/plug-queue-c...
The goal is to turn on Mesp in S-I and activate Notch in posterior S0. Tailbud elongation pulls FGF down, and so now we have NOT FGF AND Tbx6 satisfied in S-I! All that is needed is Notch! (18/n)
February 8, 2026 at 5:51 AM
The goal is to turn on Mesp in S-I and activate Notch in posterior S0. Tailbud elongation pulls FGF down, and so now we have NOT FGF AND Tbx6 satisfied in S-I! All that is needed is Notch! (18/n)