#therapeuticpotential
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itmat.bsky.social
#TherapeuticPotential of combining #IRE1α and #KRAS inhibition in #PancreaticDuctalAdenocarcinoma doi.org/10.1073/pnas... #PDAC #Hypoxia #Oncology #LiverCancer #SolidTumor #TranslationalScience
IRE1α–XBP1s signaling links lipid homeostasis to hypoxic maladaptation and KRAS inhibitor responses in pancreatic ductal adenocarcinoma | PNAS
Pancreatic ductal adenocarcinoma (PDAC) is among the most hypoxic human tumors. Because fatty acid (FA) desaturation is oxygen-dependent, hypoxia c...
doi.org
September 24, 2026 at 10:37 PM
sigtrans-sttt.bsky.social
This review outlines current knowledge on #Tregs, highlighting their role in #ImmuneHomeostasis & self-tolerance, and explores their #TherapeuticPotential across diseases, addressing challenges in tissue-specific targeting. @fudan-university.bsky.social

#STTT: doi.org/10.1038/s413...
November 24, 2025 at 12:25 PM
amm-journal.org
This review summarizes the recent findings of #SREBPs mainly in terms of physiologic activation processes, regulatory processes, related diseases, and publicly available #SmallMoleculeInhibitors with #therapeuticpotential.

#OpenAccess: amm-journal.org/index.php/20...

#medsky #medicalresearch
Therapeutic strategies targeting SREBP transcription factors
Mechanism of action underlying SREBP in different diseases and its targeted inhibition for disease prevention and treatment.
amm-journal.org
June 16, 2025 at 10:00 AM
biomedicines.bsky.social
🌿 From cardiovascular disease and fibrosis to oxidative stress and cancer, alamandine is attracting growing research attention. This scoping review explores its mechanisms of action and potential clinical applications. #Alamandine #TherapeuticPotential
mdpi.com/2227-9059/13...
September 23, 2026 at 1:13 AM
medcomm.bsky.social
#Review in #MedComm @wiley.com
Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential doi.org/10.1002/mco2...

#BiologicalFunction #Classification #development #DendriticCell #Origin #TherapeuticPotential
Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential
This review systematically summarizes dendritic cells (DCs) originating from hematopoietic stem cells, their major subsets (cDC1s, cDC2s, pDCs, moDCs, LCs) and core functions (antigen capture/present...
doi.org
November 7, 2025 at 8:20 AM
intheprezent.bsky.social
#TherapeuticPotential
#DepressionTreatment
April 5, 2026 at 10:17 PM
karl-theodor.mastodon.social.ap.brid.gy
2019 Feb.🌱 #cannabinoids in #cancertreatment: #therapeuticpotential and #legislation ➡️ learn more: https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/

#wissenschaft #science #studie #demokratie #medizin #politik #merz #Söder #bas #Schwerdtner #klingbeil #thorstenfrei #reiche #huber #kulturkampf […]
Original post on mastodon.social
mastodon.social
November 26, 2025 at 2:34 PM
karl-theodor.mastodon.social.ap.brid.gy
2019 Feb.🌱 #cannabinoids in #cancertreatment: #therapeuticpotential and #legislation ➡️ learn more: https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/
Cannabinoids in cancer treatment: Therapeutic potential and legislation Barbara Dariš 1,*, Mojca Tancer Verboten 2, Željko Knez 1,3, Polonca Ferk 4 Author information Article notes Copyright and License information PMCID: PMC6387667 PMID: 30172249 Abstract The plant Cannabis sativa L. has been used as an herbal remedy for centuries and is the most important source of phytocannabinoids. The endocannabinoid system (ECS) consists of receptors, endogenous ligands (endocannabinoids) and metabolizing enzymes, and plays an important role in different physiological and pathological processes. Phytocannabinoids and synthetic cannabinoids can interact with the components of ECS or other cellular pathways and thus affect the development/progression of diseases, including cancer. In cancer patients, cannabinoids have primarily been used as a part of palliative care to alleviate pain, relieve nausea and stimulate appetite. In addition, numerous cell culture and animal studies showed antitumor effects of cannabinoids in various cancer types. https://pmc.ncbi.nlm.nih.gov/articles/PMC6387667/
November 21, 2025 at 7:56 AM
rmatheists.bsky.social
MOBE: A Breakthrough in Gene Editing

www.rockymountainatheists.ca/post/mobe-a-...

#RockyMountainAtheists #rma #WesternCanadaReason #wecanreason #freedomfromreligion #criticalthinking #skeptics #science
#MOBE #GeneEditing #GeneticResearch #TherapeuticPotential #CRISPR
MOBE: A Breakthrough in Gene Editing
MOBE offers the ability to make multiple specific point mutations at once, reducing crosstalk and increasing efficiency.
www.rockymountainatheists.ca
May 27, 2024 at 3:25 PM
bio-integration.org
This commentary summarizes the mechanistic functions of microRNA-223 (#miR223) in #HepaticStellateCell activation and #fibrosis, discusses its #therapeuticpotential and highlights it as a complex but intriguing target for #antifibrotic treatment.

#OpenAccess: bio-integration.org/micrornas-li...
MicroRNAs in Liver Fibrosis: Unraveling Intercellular Crosstalk and the Regulatory Functions of MicroRNA-223
Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix accumulation, which in turn is driven by activation of hepatic stellate cel...
bio-integration.org
July 9, 2025 at 11:44 AM
purescience.news
Vagus nerve stimulation changes brain chemistry, hinting at therapeutic potential #Science #HealthandMedicine #Neurology #VagusNerveStimulation #BrainChemistry #TherapeuticPotential
Vagus nerve stimulation changes brain chemistry, hinting at therapeutic potential
A recent study published in Psychophysiology provides new insights into how stimulating the vagus nerve through the ear might influence brain function. Researchers found that a single 30-minute session...
purescience.news
March 19, 2025 at 9:27 PM