Zack Wheeler underwent a thrombolysis procedure to remove a blood clot in his right upper extremity this morning, the Phillies said. His timeline for recovery is “to be determined.”
August 18, 2025 at 7:35 PM
Zack Wheeler underwent a thrombolysis procedure to remove a blood clot in his right upper extremity this morning, the Phillies said. His timeline for recovery is “to be determined.”
Fresh blog: STRATIFY trial for PE
Peripheral tPA infusion is EQUALLY EFFECTIVE as compared to ultrasound-assisted thrombolysis
Catheter-directed thrombolysis for PE is dead
We can get the same benefits with peripheral tPA infusions (w/o procedural costs & complications)... #1/2 #EMIMCC
Peripheral tPA infusion is EQUALLY EFFECTIVE as compared to ultrasound-assisted thrombolysis
Catheter-directed thrombolysis for PE is dead
We can get the same benefits with peripheral tPA infusions (w/o procedural costs & complications)... #1/2 #EMIMCC
March 6, 2026 at 3:06 PM
Fresh blog: STRATIFY trial for PE
Peripheral tPA infusion is EQUALLY EFFECTIVE as compared to ultrasound-assisted thrombolysis
Catheter-directed thrombolysis for PE is dead
We can get the same benefits with peripheral tPA infusions (w/o procedural costs & complications)... #1/2 #EMIMCC
Peripheral tPA infusion is EQUALLY EFFECTIVE as compared to ultrasound-assisted thrombolysis
Catheter-directed thrombolysis for PE is dead
We can get the same benefits with peripheral tPA infusions (w/o procedural costs & complications)... #1/2 #EMIMCC
Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. Research findings are summarized in a new Quick Take video. nej.md/4lfwHrd
#MedSky #NeuroSky
#MedSky #NeuroSky
April 6, 2025 at 7:01 PM
Extending the treatment window for intravenous thrombolysis beyond 4.5 hours may benefit patients with posterior circulation ischemic stroke. Research findings are summarized in a new Quick Take video. nej.md/4lfwHrd
#MedSky #NeuroSky
#MedSky #NeuroSky
“Time is brain” for cell therapies?🧠
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
November 18, 2025 at 8:07 PM
“Time is brain” for cell therapies?🧠
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Our #AdvSci perspective😆
@rrust.bsky.social
@dominikusbrian.com
@lydenlab.bsky.social
#StemCellTherapy for #Stroke should be timed to a biomarker-defined “window of receptivity”, not just the thrombolysis clock
advanced.onlinelibrary.wiley.com/doi/10.1002/...
Causes appear to be drop in smoking rates and improvements to stroke and heart attack treatments
February 4, 2025 at 4:04 PM
Causes appear to be drop in smoking rates and improvements to stroke and heart attack treatments
I love the PITT but this scene requires correction
A patient develops angioedema after stroke thrombolysis
To intubate or not to intubate?
Someone saves the day with epinephrine.
Can you see the error? (#1/3) #EMIMCC
A patient develops angioedema after stroke thrombolysis
To intubate or not to intubate?
Someone saves the day with epinephrine.
Can you see the error? (#1/3) #EMIMCC
March 13, 2025 at 3:19 PM
I love the PITT but this scene requires correction
A patient develops angioedema after stroke thrombolysis
To intubate or not to intubate?
Someone saves the day with epinephrine.
Can you see the error? (#1/3) #EMIMCC
A patient develops angioedema after stroke thrombolysis
To intubate or not to intubate?
Someone saves the day with epinephrine.
Can you see the error? (#1/3) #EMIMCC
Right-handed pitcher Zack Wheeler underwent a successful thrombolysis procedure to remove a blood clot in his right upper extremity this morning by Dr. Paul DiMuzio at Thomas Jefferson University Hospital.
Further treatment and a subsequent timeline of recovery for Wheeler is to be determined.
Further treatment and a subsequent timeline of recovery for Wheeler is to be determined.
August 18, 2025 at 7:49 PM
Right-handed pitcher Zack Wheeler underwent a successful thrombolysis procedure to remove a blood clot in his right upper extremity this morning by Dr. Paul DiMuzio at Thomas Jefferson University Hospital.
Further treatment and a subsequent timeline of recovery for Wheeler is to be determined.
Further treatment and a subsequent timeline of recovery for Wheeler is to be determined.
Ukraine received this tranche thanks to improvements in stroke treatment in hospitals, particularly the increased use of thrombolysis to dissolve blood clots.
September 28, 2026 at 5:44 PM
Ukraine received this tranche thanks to improvements in stroke treatment in hospitals, particularly the increased use of thrombolysis to dissolve blood clots.
🩺10 year short-term outcomes of a therapeutic stepwise approach involving low-dose systemic thrombolysis for managing acute portomesenteric thrombosis
#POSTER WED-340 by Kohilan Gananandan (UCL) reports on a decade-long structured approach using low-dose thrombolysis for acute thrombosis
#EASL2025
#POSTER WED-340 by Kohilan Gananandan (UCL) reports on a decade-long structured approach using low-dose thrombolysis for acute thrombosis
#EASL2025
May 7, 2025 at 1:18 PM
Updated with the news that Zack Wheeler underwent a thrombolysis procedure to remove his blood clot. That's very good news, but his prognosis still unknown.
Injuries Put the Seasons of Zack Wheeler and Josh Hader in Doubt blogs.fangraphs.com/injuries-put...
Injuries Put the Seasons of Zack Wheeler and Josh Hader in Doubt
The Phillies’ ace and the Astros’ closer, both All-Stars, are dealing with significant shoulder problems.
blogs.fangraphs.com
August 19, 2025 at 2:24 PM
Updated with the news that Zack Wheeler underwent a thrombolysis procedure to remove his blood clot. That's very good news, but his prognosis still unknown.
Did you know that mechanical thrombectomy for stroke is 7 times more effective than thrombolysis for MI? It saves lives, reduces disability. Much of the UK still doesn’t have 24hrs access to thrombectomy and only 4% of stroke patients get one. #anaesthesia2025
May 20, 2025 at 9:51 AM
Did you know that mechanical thrombectomy for stroke is 7 times more effective than thrombolysis for MI? It saves lives, reduces disability. Much of the UK still doesn’t have 24hrs access to thrombectomy and only 4% of stroke patients get one. #anaesthesia2025
Extremely relevant? WTF is "Thombolysis?"
Short version - "Thrombolysis, also known as thrombolytic therapy or fibrinolytic therapy, is a treatment that dissolves blood clots to restore normal blood flow."
Short version - "Thrombolysis, also known as thrombolytic therapy or fibrinolytic therapy, is a treatment that dissolves blood clots to restore normal blood flow."
August 18, 2025 at 7:46 PM
Extremely relevant? WTF is "Thombolysis?"
Short version - "Thrombolysis, also known as thrombolytic therapy or fibrinolytic therapy, is a treatment that dissolves blood clots to restore normal blood flow."
Short version - "Thrombolysis, also known as thrombolytic therapy or fibrinolytic therapy, is a treatment that dissolves blood clots to restore normal blood flow."
I have colleagues who seen what you described (pre and post CtPA thrombolysis). Personally I had a case PE + DVT confirmed on scans. Post thrombolysis. DVT is gone. pe has residual.
February 4, 2025 at 9:55 AM
I have colleagues who seen what you described (pre and post CtPA thrombolysis). Personally I had a case PE + DVT confirmed on scans. Post thrombolysis. DVT is gone. pe has residual.
Hier übrigens mal die ellenlange skills-and-expertise-Liste von Herrn Kleinschnitz. Quelle: ResearchGate
LongCovid sehe ich hier nicht.
PS: Der Nobelpreisträger, mit dem ich drei Papers veröffentlichte, sagte immer:
„Wer sich in mehr als 20 Themen als Experte darstellt, ist unseriös!“
LongCovid sehe ich hier nicht.
PS: Der Nobelpreisträger, mit dem ich drei Papers veröffentlichte, sagte immer:
„Wer sich in mehr als 20 Themen als Experte darstellt, ist unseriös!“
November 23, 2025 at 5:00 PM
Hier übrigens mal die ellenlange skills-and-expertise-Liste von Herrn Kleinschnitz. Quelle: ResearchGate
LongCovid sehe ich hier nicht.
PS: Der Nobelpreisträger, mit dem ich drei Papers veröffentlichte, sagte immer:
„Wer sich in mehr als 20 Themen als Experte darstellt, ist unseriös!“
LongCovid sehe ich hier nicht.
PS: Der Nobelpreisträger, mit dem ich drei Papers veröffentlichte, sagte immer:
„Wer sich in mehr als 20 Themen als Experte darstellt, ist unseriös!“
Link to fresh blog below
The trial surely has limitations, but it's been increasingly clear that catheter-directed thrombolysis is silly for over a decade now
TBH, this is a wild story about device manufacturers using sponsored RCTs to torture EBM
emcrit.org/pulmcrit/cdt/
The trial surely has limitations, but it's been increasingly clear that catheter-directed thrombolysis is silly for over a decade now
TBH, this is a wild story about device manufacturers using sponsored RCTs to torture EBM
emcrit.org/pulmcrit/cdt/
PulmCrit: Catheter-directed lysis = Peripheral lysis for PE (STRATIFY trial!)
Catheter-directed thrombolysis for PE has always been a silly idea, for numerous reasons: Clots are widely distributed throughout both lungs. 100% of the
emcrit.org
March 6, 2026 at 3:06 PM
Link to fresh blog below
The trial surely has limitations, but it's been increasingly clear that catheter-directed thrombolysis is silly for over a decade now
TBH, this is a wild story about device manufacturers using sponsored RCTs to torture EBM
emcrit.org/pulmcrit/cdt/
The trial surely has limitations, but it's been increasingly clear that catheter-directed thrombolysis is silly for over a decade now
TBH, this is a wild story about device manufacturers using sponsored RCTs to torture EBM
emcrit.org/pulmcrit/cdt/
Got it. But isn’t that thrombectomy, not thrombolysis? Or are the terms interchangeable?
Depends on the type and size of clot and where it’s lodged. Drugs can break up a clot, but if in an artery that leads to, say, the brain, you kinda don’t want pieces of the clot breaking off. Hence surgery to just yank it out.
August 19, 2025 at 12:57 AM
Got it. But isn’t that thrombectomy, not thrombolysis? Or are the terms interchangeable?
🔁 @Ken_Rosenthal retweeted
@charlottevarnes Zack Wheeler underwent a successful thrombolysis procedure to remove the blood clot in his right upper extremity today, the Phillies announced.
@charlottevarnes Zack Wheeler underwent a successful thrombolysis procedure to remove the blood clot in his right upper extremity today, the Phillies announced.
August 18, 2025 at 7:38 PM
🔁 @Ken_Rosenthal retweeted
@charlottevarnes Zack Wheeler underwent a successful thrombolysis procedure to remove the blood clot in his right upper extremity today, the Phillies announced.
@charlottevarnes Zack Wheeler underwent a successful thrombolysis procedure to remove the blood clot in his right upper extremity today, the Phillies announced.
From @nejm.org 🫁
Catheter-directed #thrombolysis plus #anticoagulation was associated with reduced risk of mortality among patients with acute #PulmonaryEmbolism.
#PulmSky #CriticalCare
Catheter-directed #thrombolysis plus #anticoagulation was associated with reduced risk of mortality among patients with acute #PulmonaryEmbolism.
#PulmSky #CriticalCare
Catheter-Directed Thrombolysis Plus Anticoagulation Supported in Acute PE
Among patients with acute PE, those who undergo catheter-directed thrombolysis plus anticoagulation therapy show better outcomes.
www.pulmonologyadvisor.com
October 2, 2026 at 11:45 PM
From @nejm.org 🫁
Catheter-directed #thrombolysis plus #anticoagulation was associated with reduced risk of mortality among patients with acute #PulmonaryEmbolism.
#PulmSky #CriticalCare
Catheter-directed #thrombolysis plus #anticoagulation was associated with reduced risk of mortality among patients with acute #PulmonaryEmbolism.
#PulmSky #CriticalCare
It is frankly crazy to think how much modern medicine has changed even just in the last 50 years!
Thrombolysis to prevent the irreversible damage of a heart attack.
And
Use of inhaled steroids to prevent recurrence of asthma attacks both only widespread in the 1980s!
Thrombolysis to prevent the irreversible damage of a heart attack.
And
Use of inhaled steroids to prevent recurrence of asthma attacks both only widespread in the 1980s!
Do you ever just think about the fact penicillin is less than 100 years old?
May 13, 2026 at 3:20 PM
It is frankly crazy to think how much modern medicine has changed even just in the last 50 years!
Thrombolysis to prevent the irreversible damage of a heart attack.
And
Use of inhaled steroids to prevent recurrence of asthma attacks both only widespread in the 1980s!
Thrombolysis to prevent the irreversible damage of a heart attack.
And
Use of inhaled steroids to prevent recurrence of asthma attacks both only widespread in the 1980s!
🫀 Clot buster cuts lung clot deaths
A Czech trial of 558 people with dangerous lung clots found feeding clot dissolving drugs straight into the lung artery cut deaths and repeat clots to under 1%, against nearly 7% on blood thinners alone.
🔗 doi.org/10.1056/nejmoa2608012
#Health #Medicine 🧪
A Czech trial of 558 people with dangerous lung clots found feeding clot dissolving drugs straight into the lung artery cut deaths and repeat clots to under 1%, against nearly 7% on blood thinners alone.
🔗 doi.org/10.1056/nejmoa2608012
#Health #Medicine 🧪
Catheter-Directed Thrombolysis in Intermediate-High–Risk Pulmonary Embolism | NEJM
Whether catheter-directed thrombolysis improves clinical outcomes in patients with intermediate-high–risk pulmonary embolism, as compared with anticoagulation alone, is uncertain. In this multicent...
doi.org
September 4, 2026 at 5:11 AM
🫀 Clot buster cuts lung clot deaths
A Czech trial of 558 people with dangerous lung clots found feeding clot dissolving drugs straight into the lung artery cut deaths and repeat clots to under 1%, against nearly 7% on blood thinners alone.
🔗 doi.org/10.1056/nejmoa2608012
#Health #Medicine 🧪
A Czech trial of 558 people with dangerous lung clots found feeding clot dissolving drugs straight into the lung artery cut deaths and repeat clots to under 1%, against nearly 7% on blood thinners alone.
🔗 doi.org/10.1056/nejmoa2608012
#Health #Medicine 🧪
So they also sell an at home thrombolysis kit?
March 6, 2025 at 1:59 PM
So they also sell an at home thrombolysis kit?
More on Zack Wheeler’s thrombolysis procedure with comments from Rob Thomson: www.nytimes.com/athletic/656...
Zack Wheeler undergoes procedure to remove blood clot
www.nytimes.com
August 18, 2025 at 8:44 PM
More on Zack Wheeler’s thrombolysis procedure with comments from Rob Thomson: www.nytimes.com/athletic/656...