🧬 Tough DNA target, big impact! Prof. Rusling's lab @daverusling.bsky.social shows that a simple #nucleobase modification enables TFOs to repress MYC #promoteractivity by ~80%, even in a challenging GC-rich DNA region. doi.org/10.1093/nar/... #triplexforming #oligonucleotides
🧬 Tough DNA target, big impact! Prof. Rusling's lab @daverusling.bsky.social shows that a simple #nucleobase modification enables TFOs to repress MYC #promoteractivity by ~80%, even in a challenging GC-rich DNA region. doi.org/10.1093/nar/... #triplexforming #oligonucleotides