TBH, no politician should be able to
say what can or can not be done over something doctor's go to school for umpteen years, but their 6 week course taught them enough.
These state bans!
Ok, there's a blood test, Trisomy 18. It's not tested until 17-22 weeks.
Kate Cox share.google/d0HW1PYLlxsO...
say what can or can not be done over something doctor's go to school for umpteen years, but their 6 week course taught them enough.
These state bans!
Ok, there's a blood test, Trisomy 18. It's not tested until 17-22 weeks.
Kate Cox share.google/d0HW1PYLlxsO...
Kate Cox, Texas woman denied an abortion, announces she's pregnant again
Kate Cox, a Texas woman who sued her state when she was denied an abortion there, announced that she is pregnant during the DNC’s delegate roll call.
share.google
October 4, 2026 at 9:16 PM
TBH, no politician should be able to
say what can or can not be done over something doctor's go to school for umpteen years, but their 6 week course taught them enough.
These state bans!
Ok, there's a blood test, Trisomy 18. It's not tested until 17-22 weeks.
Kate Cox share.google/d0HW1PYLlxsO...
say what can or can not be done over something doctor's go to school for umpteen years, but their 6 week course taught them enough.
These state bans!
Ok, there's a blood test, Trisomy 18. It's not tested until 17-22 weeks.
Kate Cox share.google/d0HW1PYLlxsO...
I'm a bit conflicted on removing a whole extra chromosome but also... it's complicated. My kid has trisomy 13. Does the extra genetic material play a part in determining who they are, or is it only the cause of conditions that are barriers to how they want their life to be? I don't know.
October 2, 2026 at 9:53 PM
I'm a bit conflicted on removing a whole extra chromosome but also... it's complicated. My kid has trisomy 13. Does the extra genetic material play a part in determining who they are, or is it only the cause of conditions that are barriers to how they want their life to be? I don't know.
Children (adults) with trisomy 21 are especially empathetic and openly show their affection. These are my beautiful experiences in this regard. 💗
October 2, 2026 at 6:33 PM
Children (adults) with trisomy 21 are especially empathetic and openly show their affection. These are my beautiful experiences in this regard. 💗
Down Syndrome: Discovery and Debate
Down syndrome, or trisomy 21, was clinically described by John Langdon Down in 1866. In 1959, Jérôme Lejeune, Marthe Gautier and Raymond Turpin published the finding that the condition had a chromosomal basis, but historical credit remains contested—
Down syndrome, or trisomy 21, was clinically described by John Langdon Down in 1866. In 1959, Jérôme Lejeune, Marthe Gautier and Raymond Turpin published the finding that the condition had a chromosomal basis, but historical credit remains contested—
September 26, 2026 at 6:18 PM
Down Syndrome: Discovery and Debate
Down syndrome, or trisomy 21, was clinically described by John Langdon Down in 1866. In 1959, Jérôme Lejeune, Marthe Gautier and Raymond Turpin published the finding that the condition had a chromosomal basis, but historical credit remains contested—
Down syndrome, or trisomy 21, was clinically described by John Langdon Down in 1866. In 1959, Jérôme Lejeune, Marthe Gautier and Raymond Turpin published the finding that the condition had a chromosomal basis, but historical credit remains contested—
New clinical trial
Phase 1B Trial on Escalating Doses of Memantine in Down Syndrome
#ClinicalTrials #AlzheimersDisease #EndAlz #Neurology
Phase 1B Trial on Escalating Doses of Memantine in Down Syndrome
#ClinicalTrials #AlzheimersDisease #EndAlz #Neurology
Phase 1B Trial on Escalating Doses of Memantine in Down Syndrome
Down syndrome (DS) is typically caused by an extra chromosome 21 in the cell nucleus (trisomy 21, or T21). T21 is both the most common cause of genetically defined intellectual disability and the earliest documented cause of Alzheimer's disease (AD)-type pathology. Currently, ...
brain-regeneration.com
September 26, 2026 at 4:50 PM
New clinical trial
Phase 1B Trial on Escalating Doses of Memantine in Down Syndrome
#ClinicalTrials #AlzheimersDisease #EndAlz #Neurology
Phase 1B Trial on Escalating Doses of Memantine in Down Syndrome
#ClinicalTrials #AlzheimersDisease #EndAlz #Neurology
Source: I found out at 20 weeks that my child had severe fetal abnormalities (misformed organs) and that it 'probably wasn't viable' but that the testing to confirm would take weeks and I had to have the D&C by 21 weeks or it gets complicated. Amnio confirmed trisomy so I went ahead
September 24, 2026 at 5:49 PM
Source: I found out at 20 weeks that my child had severe fetal abnormalities (misformed organs) and that it 'probably wasn't viable' but that the testing to confirm would take weeks and I had to have the D&C by 21 weeks or it gets complicated. Amnio confirmed trisomy so I went ahead
Dear Amanda,
I'm sorry that happened to you. I had Trisomy 18 Edwards Disease I aborted my son at 20 weeks he had no skull, an ultrasound and amniocentesis confirmed complications.
At all times my life, my dignity and my care was the priority of doctors and nurses🇦🇺
It should've been for you also.
I'm sorry that happened to you. I had Trisomy 18 Edwards Disease I aborted my son at 20 weeks he had no skull, an ultrasound and amniocentesis confirmed complications.
At all times my life, my dignity and my care was the priority of doctors and nurses🇦🇺
It should've been for you also.
September 22, 2026 at 12:13 PM
Dear Amanda,
I'm sorry that happened to you. I had Trisomy 18 Edwards Disease I aborted my son at 20 weeks he had no skull, an ultrasound and amniocentesis confirmed complications.
At all times my life, my dignity and my care was the priority of doctors and nurses🇦🇺
It should've been for you also.
I'm sorry that happened to you. I had Trisomy 18 Edwards Disease I aborted my son at 20 weeks he had no skull, an ultrasound and amniocentesis confirmed complications.
At all times my life, my dignity and my care was the priority of doctors and nurses🇦🇺
It should've been for you also.
A Trisomy 21 Model Atlas reveals conserved dosage effects and context-specific transcriptional responses across mouse and human models of Down syndrome https://www.biorxiv.org/content/10.64898/2026.09.20.751055v1
September 21, 2026 at 6:30 PM
A Trisomy 21 Model Atlas reveals conserved dosage effects and context-specific transcriptional responses across mouse and human models of Down syndrome https://www.biorxiv.org/content/10.64898/2026.09.20.751055v1
A Trisomy 21 Model Atlas reveals conserved dosage effects and context-specific transcriptional responses across mouse and human models of Down syndrome https://www.biorxiv.org/content/10.64898/2026.09.20.751055v1
September 21, 2026 at 6:30 PM
A Trisomy 21 Model Atlas reveals conserved dosage effects and context-specific transcriptional responses across mouse and human models of Down syndrome https://www.biorxiv.org/content/10.64898/2026.09.20.751055v1
ugh
sadly, this is a GREAT idea
we live in utah, a state that made talking abt options for mid-term abortions impossible—i was blocked from pre-planning for potentially devastating news of a chromosomal trisomy that wld be 100% fatal, end-term (all was well)
bc we want EVERY option for our girls
sadly, this is a GREAT idea
we live in utah, a state that made talking abt options for mid-term abortions impossible—i was blocked from pre-planning for potentially devastating news of a chromosomal trisomy that wld be 100% fatal, end-term (all was well)
bc we want EVERY option for our girls
September 17, 2026 at 3:37 PM
ugh
sadly, this is a GREAT idea
we live in utah, a state that made talking abt options for mid-term abortions impossible—i was blocked from pre-planning for potentially devastating news of a chromosomal trisomy that wld be 100% fatal, end-term (all was well)
bc we want EVERY option for our girls
sadly, this is a GREAT idea
we live in utah, a state that made talking abt options for mid-term abortions impossible—i was blocked from pre-planning for potentially devastating news of a chromosomal trisomy that wld be 100% fatal, end-term (all was well)
bc we want EVERY option for our girls
Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis https://www.biorxiv.org/content/10.64898/2026.09.14.751618v1
September 17, 2026 at 10:33 AM
Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis https://www.biorxiv.org/content/10.64898/2026.09.14.751618v1
Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis https://www.biorxiv.org/content/10.64898/2026.09.14.751618v1
September 17, 2026 at 10:33 AM
Aberrant PCM1 accumulation in Trisomy 21 mislocalizes E3 ligases, delaying primary ciliogenesis https://www.biorxiv.org/content/10.64898/2026.09.14.751618v1
Este análisis de la sensibilidad y especificidad de prueba prenatal no invasiva (NIPT) para trisomías habituales demuestra una menor sensibilidad en embarazos conseguidos por técnicas de reproducción asistida que en naturales:
buff.ly/6jHzkDU
#bianorbiotech #NIPT #trisomy #pregnancy #sensitivity
buff.ly/6jHzkDU
#bianorbiotech #NIPT #trisomy #pregnancy #sensitivity
https://www.sciencedirect.com/science/article/pii/S0015028226002360
www.sciencedirect.com
September 17, 2026 at 6:36 AM
Este análisis de la sensibilidad y especificidad de prueba prenatal no invasiva (NIPT) para trisomías habituales demuestra una menor sensibilidad en embarazos conseguidos por técnicas de reproducción asistida que en naturales:
buff.ly/6jHzkDU
#bianorbiotech #NIPT #trisomy #pregnancy #sensitivity
buff.ly/6jHzkDU
#bianorbiotech #NIPT #trisomy #pregnancy #sensitivity
'"Trisomy 18 is considered a terminal condition....so according to this SB 31 legislation, an abortion was legal because that was my clinical judgement....But Attorney General Ken Paxton made a threat very publicly” to prosecute any doctor or hospital who provided Cox with an abortion.'
Tierra Walker’s Family Sues Ken Paxton and Doctors, Saying Texas Abortion Ban Caused Her Death
After 90 Doctors and Months of Crisis, a Texas Mother Tierra Walker Died Without the Abortion That Could Have Saved Her
msmagazine.com
September 16, 2026 at 6:42 PM
'"Trisomy 18 is considered a terminal condition....so according to this SB 31 legislation, an abortion was legal because that was my clinical judgement....But Attorney General Ken Paxton made a threat very publicly” to prosecute any doctor or hospital who provided Cox with an abortion.'
Reading now and what a profoundly beautiful choice to add "of us." Leave it out, and people are left further away. Add it, and we are family:
"[...] because a single crease has a high incidence in those of us with a particular chromosomal anomaly known as trisomy 21"
"[...] because a single crease has a high incidence in those of us with a particular chromosomal anomaly known as trisomy 21"
September 13, 2026 at 11:18 PM
Reading now and what a profoundly beautiful choice to add "of us." Leave it out, and people are left further away. Add it, and we are family:
"[...] because a single crease has a high incidence in those of us with a particular chromosomal anomaly known as trisomy 21"
"[...] because a single crease has a high incidence in those of us with a particular chromosomal anomaly known as trisomy 21"
I was out knocking doors last week, and I met the kindest family.
Joy and Eric invited me into their home to meet Cora, their daughter who is beating all the odds while living with a condition known as Trisomy 18.
Joy and Eric invited me into their home to meet Cora, their daughter who is beating all the odds while living with a condition known as Trisomy 18.
September 11, 2026 at 9:58 PM
I was out knocking doors last week, and I met the kindest family.
Joy and Eric invited me into their home to meet Cora, their daughter who is beating all the odds while living with a condition known as Trisomy 18.
Joy and Eric invited me into their home to meet Cora, their daughter who is beating all the odds while living with a condition known as Trisomy 18.
That's not eugenics, that's progress
As a woman who terminated a pregnancy because of trisomy 2l I'm grateful there are now earlier blood tests available so women don't have to wait for second trimester amniocentesis
As a woman who terminated a pregnancy because of trisomy 2l I'm grateful there are now earlier blood tests available so women don't have to wait for second trimester amniocentesis
September 11, 2026 at 12:29 PM
That's not eugenics, that's progress
As a woman who terminated a pregnancy because of trisomy 2l I'm grateful there are now earlier blood tests available so women don't have to wait for second trimester amniocentesis
As a woman who terminated a pregnancy because of trisomy 2l I'm grateful there are now earlier blood tests available so women don't have to wait for second trimester amniocentesis
It's more than a slippery slope. It's a lubed-up slide designed to dispose of "expensive" and inconvenient people. Not that different from the targeted abortion policies led by the nordic countries that have all but eliminated disabilities like Trisomy-21. Eugenics.
September 11, 2026 at 10:27 AM
It's more than a slippery slope. It's a lubed-up slide designed to dispose of "expensive" and inconvenient people. Not that different from the targeted abortion policies led by the nordic countries that have all but eliminated disabilities like Trisomy-21. Eugenics.
In trisomy 21 neural progenitor cells, Laura Baxter and colleagues reveal #fasudil increases growth and reduced expression of inflammatory pathway genes doi.org/10.1242/bio....
September 10, 2026 at 11:01 AM
In trisomy 21 neural progenitor cells, Laura Baxter and colleagues reveal #fasudil increases growth and reduced expression of inflammatory pathway genes doi.org/10.1242/bio....
Most animals, no, because chromosome number and function vary so widely between species. But I double checked (bad with genetics please excuse me) and yes, chromosome 22 in Chimps is homologous to chromosome 21 in humans, and a trisomy has similar effects as in humans... so chimps are an exception!
September 9, 2026 at 3:47 AM
Most animals, no, because chromosome number and function vary so widely between species. But I double checked (bad with genetics please excuse me) and yes, chromosome 22 in Chimps is homologous to chromosome 21 in humans, and a trisomy has similar effects as in humans... so chimps are an exception!
Completely unrelated fact but apparently Chimpanzees can have down syndrome, since our chromosomal structures are analogous in some portions i believe... so they also can have a trisomy that makes them present with typical down syndrome features. There was a famous down syndrome chimp named Kanako.
September 9, 2026 at 3:15 AM
Completely unrelated fact but apparently Chimpanzees can have down syndrome, since our chromosomal structures are analogous in some portions i believe... so they also can have a trisomy that makes them present with typical down syndrome features. There was a famous down syndrome chimp named Kanako.
But can the thread counter count to "potato"?
September 5, 2026 at 7:15 PM
But can the thread counter count to "potato"?
Sequence and epigenetic characterization of chromosome 21 centromeres in a family with recurrent Trisomy 21 https://www.biorxiv.org/content/10.64898/2026.08.31.748295v1
September 3, 2026 at 4:31 PM
Sequence and epigenetic characterization of chromosome 21 centromeres in a family with recurrent Trisomy 21 https://www.biorxiv.org/content/10.64898/2026.08.31.748295v1
Sequence and epigenetic characterization of chromosome 21 centromeres in a family with recurrent Trisomy 21 https://www.biorxiv.org/content/10.64898/2026.08.31.748295v1
September 3, 2026 at 4:31 PM
Sequence and epigenetic characterization of chromosome 21 centromeres in a family with recurrent Trisomy 21 https://www.biorxiv.org/content/10.64898/2026.08.31.748295v1