#trivalent
Now we're talking!
A trivalent nasal vaccine vs mumps, measles and Covid, broadly effective vs SARS-CoV-2 variants, with expected long duration (using preS-6P), in multiple experimental models pnas.org/doi/10.1073/...
October 5, 2023 at 9:49 PM
A new trivalent vaccine based on chimeric alphaviruses shields mice and macaques from infection and CNS pathology when exposed to aerosolized forms of Venezuelan, Eastern, and Western equine encephalitis viruses.

Read more in #ScienceTranslationalMedicine: https://scim.ag/4gSP2Z3
An inactivated trivalent virion-based vaccine protects against aerosol challenge with encephalitic alphaviruses in mice and macaques
Two doses of an inactivated trivalent vaccine protect mice and macaques against disease caused by encephalitic alphaviruses.
scim.ag
October 6, 2025 at 6:08 PM
If science is so good, why haven’t they invented a trivalent Covid-19 vaccine / seasonal flu vaccine / Tums
October 3, 2025 at 11:30 PM
The flu vaccine is trivalent, meaning it protects against three main influenza viruses: a Type A(H1N1) virus, a Type A(H3N2) virus, and a Type B/Victoria lineage virus.
August 31, 2026 at 4:57 PM
Nachtrag!
Impfungen enthalten entweder zwei A-Subtypen und eine B-Linie (trivalent = drei Virusstämme) oder zwei A-Subtypen und zwei B-Linien (tetravalent = vier Virusstämme). Damit bieten diese einen Schutz vor beiden Infektionen! Egal ob A oder B!
✅✅✅✅
February 21, 2025 at 9:31 AM
We switched from quadrivalent (4 strains) to trivalent (3 strains) flu shots as a result. Really amazing stuff, masks.
We accidentally drove one of the circulating flu strains extinct early in the COVID pandemic.
Also, if 90% of people wore masks in public indoors for, say, three months, there would be a HUGE decrease in the amount of viral transmission, making it safer for everyone.

Just some thoughts!
March 10, 2025 at 9:59 AM
Vaccines do not cause autism. Trivalent vaccines do not cause autism. No shots kids get cause autism.
Trump: "We're also going to be demanding the drug companies, with respect to a certain situation -- the autism -- that they make their doses in 20% shots. So you have shot 1, shot 2, shot 3, shot 4, shot 5 ... I think you're gonna see a massive reduction in autism"
September 18, 2026 at 10:25 PM
I excitedly told my husband last night that we got trivalent rather than quadvalent this year because we got rid of 1 flu!!
We killed a whole flu unintentionally just by masking.

Imagine what we could do if we tried.

Covid does not _need_ to circulate. We don’t really have reservoirs of it. It’s not inevitable. Even now.
npr.org NPR @npr.org · Oct 17
A strain of influenza appears to have disappeared from the planet since COVID. As a result, U.S. flu vaccines have been redesigned.
October 17, 2024 at 11:11 PM
Trivalent mRNA Flu Shot More Effective Than Standard Vaccines www.medpagetoday.com/infectiousdi...
Trivalent mRNA Flu Shot More Effective Than Standard Vaccines
Randomized trial shows superiority in adults 50 and older
www.medpagetoday.com
May 9, 2026 at 12:31 PM
amenable to composition updates to address changes in genotype prevalence, may represent a promising strategy. mRNA-1403 is a trivalent mRNA-based candidate containing three mRNAs that encode for the major capsid protein 1 (VP1) of three globally prevalent NoV genotypes-GII.4,
January 16, 2025 at 5:08 PM
4/ This season’s shot:
Trivalent (3 strains: 2 influenza A + 1 influenza B)

Updated for a specific A/H3N2 strain

Minor changes, aligned with WHO guidance
August 18, 2025 at 2:58 PM
Just got a flu shot even though my brain formed the thought “soup me up trivalent daddy” and if I can push through that to be an adult in society so can you
January 5, 2026 at 4:47 PM
can someone pls buy me a bet ter pooter...,.,.,

remix of trivalent by @64abstract.bsky.social
December 8, 2024 at 7:47 AM
Ab nächstes Jahr sind die Impfungen wieder trivalent, weil es den Yamagata-B-Stamm nicht mehr gibt.
February 21, 2025 at 4:31 PM
What really annoys a chemist are the pentavalent carbon and trivalent oxygen on the left-hand diagram.
January 21, 2025 at 12:24 PM
tired of boring old trivalent chromium? try NEW and improved hexavalent chromium! twice the valences, twice the same great taste
May 12, 2025 at 5:32 AM
This was promising research for a vaccine that would encompass the class of coronaviruses. The NIG grants for vax development are cancelled taggs.hhs.gov/Content/Data...

www.nature.com/articles/s41...
A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses - npj Vaccines
npj Vaccines - A trivalent protein-based pan-Betacoronavirus vaccine elicits cross-neutralizing antibodies against a panel of coronavirus pseudoviruses
www.nature.com
June 12, 2025 at 3:36 PM
cool, what's in the trivalent vax then?
May 13, 2024 at 3:39 PM
Hope they aren’t wrong about the trivalent live polio vax I got in 1969. That would suck.
September 20, 2026 at 2:04 AM
Last one of the year: my work on the calculated stability of expanded porphyrin actinide complexes with Georg is finally published :)
pubs.acs.org/doi/full/10....
Trends in Methanol-Solvated Actinide Ions and Actinide Expanded Porphyrin Complexes
Trivalent actinide expanded porphyrin complexes have been of synthetic interest since the isolation of the series of trivalent lanthanide texaphyrin complexes in 1992, however, synthesis of these actinide-based complexes has not yet been achieved. In this work, a computational study with relativistic density functional theory was performed to determine how trivalent actinide ions (Ac3+ through Lr3+) interact with Schiff base expanded porphyrin macrocycles in a methanol solvent as an alternate pathway to stabilization. A thorough analysis of structural parameters, electronic structure, stability of microsolvation environments, and relative binding energies provided insight into the most stable structures. Trends in bonding and structure for the full actinide series are reported for methanol solvated ions, which reports actinide contraction along the series for early and mid actinides. Texaphyrin incorporates the actinide ions in a planar fashion, whereas for alaskphyrin a bent structure is more favorable; this bend results in stronger interaction energies than those calculated for the texaphyrin complexes. We also show that the redox-active expanded porphyrin ligands are able to accommodate a variety of actinides through charge transfer stabilization. Based on relative binding energy and energy decomposition analysis, it was found that texaphyrin and alaskaphyrin both exhibit a strong preference for binding to Th.
pubs.acs.org
December 19, 2024 at 2:59 PM
#NEisVoid headaches, chest pain,
high blood pressure
Shoulder pain,

holy crap either the Sanofi trivalent flu shot is overpowered.
Or CVS fucked up and gave me the moderna mRNA

,
September 24, 2026 at 5:05 AM
we're doing string diagrams and representation theory
August 6, 2026 at 10:17 PM
Australia: "Everything you need to know about this year's vaccine rollout."

Australia’s 2026 vaccine is trivalent, protecting against two influenza A strains and one B strain, including the fast-moving subclade K, known as “Super-K".
Everything you need to know about this year's winter vaccine rollout
With winter just around the corner, now is the perfect time to get vaccinated against seasonal flu and other viruses.
www.abc.net.au
April 30, 2026 at 7:23 AM
TRIVALENT: Awakening the Void is out now on Windows.
A pure abstract strategy game — no randomness, no hidden information.

Play it here: hugluck.itch.io/trivalent

#AbstractStrategy #BoardGames #IndieDev
TRIVALENT: AWAKENING THE VOID by hugluck
An accessible sci-fi abstract board game inspired by Othello and 9x9 Go.
hugluck.itch.io
March 24, 2026 at 4:38 AM