Use code SEPSIS at checkout and add any vasopressor for 20% off
March 22, 2026 at 3:32 PM
Use code SEPSIS at checkout and add any vasopressor for 20% off
You would think “vasopressin” would be the gold standard vasopressor by virtue of its name. But no. It’s not. It’s a mere second line therapy.
August 17, 2024 at 10:54 PM
You would think “vasopressin” would be the gold standard vasopressor by virtue of its name. But no. It’s not. It’s a mere second line therapy.
Maybe the amount of circulating cocaine acted as a vasopressor as well.
November 19, 2024 at 12:52 AM
Maybe the amount of circulating cocaine acted as a vasopressor as well.
PO droxidopa to wean off vasopressor infusions (instead of midodrine):
the mechanism of conversion to norepi *inside* neurons is beautiful. this may restore normal functioning of the sympathetic nervous system
no robust data yet
thoughts? criticism? experiences? #EMIMCC @ajwpharm.bsky.social
the mechanism of conversion to norepi *inside* neurons is beautiful. this may restore normal functioning of the sympathetic nervous system
no robust data yet
thoughts? criticism? experiences? #EMIMCC @ajwpharm.bsky.social
January 23, 2025 at 2:16 PM
PO droxidopa to wean off vasopressor infusions (instead of midodrine):
the mechanism of conversion to norepi *inside* neurons is beautiful. this may restore normal functioning of the sympathetic nervous system
no robust data yet
thoughts? criticism? experiences? #EMIMCC @ajwpharm.bsky.social
the mechanism of conversion to norepi *inside* neurons is beautiful. this may restore normal functioning of the sympathetic nervous system
no robust data yet
thoughts? criticism? experiences? #EMIMCC @ajwpharm.bsky.social
Less volume loading, earlier vasopressor use in sepsis potentially an explanation for both less mechanical ventilation and more vasopressor use? #emimcc
Following pandemic-era changes, many ICU outcome measures returned to prior levels.
The rates of mechanical ventilation have declined even further, while vasopressor use remained elevated above 2010s rates.
#MedSky https://ja.ma/42Jl3NO
The rates of mechanical ventilation have declined even further, while vasopressor use remained elevated above 2010s rates.
#MedSky https://ja.ma/42Jl3NO
Life Support and Outcomes Among ICU Patients
This cohort study uses data from US health systems continuously contributing to the Epic Cosmos database from 2014-2023 to characterize changes in intensive care unit (ICU) outcomes (ICU length of stay; use of mechanical ventilation or vasopressors; in-hospital mortality) and use of life support...
ja.ma
April 16, 2025 at 1:10 PM
Less volume loading, earlier vasopressor use in sepsis potentially an explanation for both less mechanical ventilation and more vasopressor use? #emimcc
It is amazing how the human body can often adapt and compensate, even to the greatest insults.
This is the LV of a patient with cardiomyopathy that underwent an emergency VT ablation under GA, only requiring minimal vasopressor support throughout.
#ansky #cardiosky #echosky #echofirst #medsky
This is the LV of a patient with cardiomyopathy that underwent an emergency VT ablation under GA, only requiring minimal vasopressor support throughout.
#ansky #cardiosky #echosky #echofirst #medsky
May 12, 2026 at 10:59 AM
It is amazing how the human body can often adapt and compensate, even to the greatest insults.
This is the LV of a patient with cardiomyopathy that underwent an emergency VT ablation under GA, only requiring minimal vasopressor support throughout.
#ansky #cardiosky #echosky #echofirst #medsky
This is the LV of a patient with cardiomyopathy that underwent an emergency VT ablation under GA, only requiring minimal vasopressor support throughout.
#ansky #cardiosky #echosky #echofirst #medsky
If it responds to *any* vasopressor it isn’t refractory.
February 7, 2026 at 6:58 AM
If it responds to *any* vasopressor it isn’t refractory.
Highlighting and writing in the margins of my vasopressor and inotrope handbook and my coworkers are making fun of me for it but they won't be laughing when I can tell them the the half life of every medication their patient is on!
June 2, 2024 at 10:05 PM
Highlighting and writing in the margins of my vasopressor and inotrope handbook and my coworkers are making fun of me for it but they won't be laughing when I can tell them the the half life of every medication their patient is on!
Kinda unfair that in a whole category called “vasopressors” the one actually called “vasopressin” is only the number 2 choice of vasopressor.
April 23, 2024 at 3:40 PM
Kinda unfair that in a whole category called “vasopressors” the one actually called “vasopressin” is only the number 2 choice of vasopressor.
I think it's unnecessarily caustic (and largely incorrect) to call it virtue signalling. Everyone has different risk thresholds, and their own mitigation strategies. I'm not generally a drawer-upper but I see no reason to demean those who know they'd be stressed getting a vasopressor in a hurry.
July 12, 2025 at 8:04 AM
I think it's unnecessarily caustic (and largely incorrect) to call it virtue signalling. Everyone has different risk thresholds, and their own mitigation strategies. I'm not generally a drawer-upper but I see no reason to demean those who know they'd be stressed getting a vasopressor in a hurry.
5) The paper states: "No severe adverse events or escalation of therapy were observed. Vasopressor use, fluid administration, and other hemodynamic parameters were comparable between groups, and no episodes of clinically significant hypotension occurred."
April 10, 2026 at 8:18 AM
5) The paper states: "No severe adverse events or escalation of therapy were observed. Vasopressor use, fluid administration, and other hemodynamic parameters were comparable between groups, and no episodes of clinically significant hypotension occurred."
Today's Paper of the Day is:
𝐒𝐭𝐚𝐭𝐞 𝐨𝐟 𝐒𝐡𝐨𝐜𝐤: 𝐂𝐨𝐧𝐭𝐞𝐦𝐩𝐨𝐫𝐚𝐫𝐲 𝐕𝐚𝐬𝐨𝐩𝐫𝐞𝐬𝐬𝐨𝐫 𝐚𝐧𝐝 𝐈𝐧𝐨𝐭𝐫𝐨𝐩𝐞 𝐔𝐬𝐞 𝐢𝐧 𝐂𝐚𝐫𝐝𝐢𝐨𝐠𝐞𝐧𝐢𝐜 𝐒𝐡𝐨𝐜𝐤
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date
𝐒𝐭𝐚𝐭𝐞 𝐨𝐟 𝐒𝐡𝐨𝐜𝐤: 𝐂𝐨𝐧𝐭𝐞𝐦𝐩𝐨𝐫𝐚𝐫𝐲 𝐕𝐚𝐬𝐨𝐩𝐫𝐞𝐬𝐬𝐨𝐫 𝐚𝐧𝐝 𝐈𝐧𝐨𝐭𝐫𝐨𝐩𝐞 𝐔𝐬𝐞 𝐢𝐧 𝐂𝐚𝐫𝐝𝐢𝐨𝐠𝐞𝐧𝐢𝐜 𝐒𝐡𝐨𝐜𝐤
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date
January 27, 2025 at 10:50 AM
Today's Paper of the Day is:
𝐒𝐭𝐚𝐭𝐞 𝐨𝐟 𝐒𝐡𝐨𝐜𝐤: 𝐂𝐨𝐧𝐭𝐞𝐦𝐩𝐨𝐫𝐚𝐫𝐲 𝐕𝐚𝐬𝐨𝐩𝐫𝐞𝐬𝐬𝐨𝐫 𝐚𝐧𝐝 𝐈𝐧𝐨𝐭𝐫𝐨𝐩𝐞 𝐔𝐬𝐞 𝐢𝐧 𝐂𝐚𝐫𝐝𝐢𝐨𝐠𝐞𝐧𝐢𝐜 𝐒𝐡𝐨𝐜𝐤
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date
𝐒𝐭𝐚𝐭𝐞 𝐨𝐟 𝐒𝐡𝐨𝐜𝐤: 𝐂𝐨𝐧𝐭𝐞𝐦𝐩𝐨𝐫𝐚𝐫𝐲 𝐕𝐚𝐬𝐨𝐩𝐫𝐞𝐬𝐬𝐨𝐫 𝐚𝐧𝐝 𝐈𝐧𝐨𝐭𝐫𝐨𝐩𝐞 𝐔𝐬𝐞 𝐢𝐧 𝐂𝐚𝐫𝐝𝐢𝐨𝐠𝐞𝐧𝐢𝐜 𝐒𝐡𝐨𝐜𝐤
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date
Rolling drug shortages have been a feature of hospital medicine for the last 15 years: The 2017 norepinephrine shortage is actually how we know that norepi is superior to neosynephrine as a vasopressor… because more people died when we ran out of norepi and had to use neo.
August 20, 2025 at 9:04 AM
Rolling drug shortages have been a feature of hospital medicine for the last 15 years: The 2017 norepinephrine shortage is actually how we know that norepi is superior to neosynephrine as a vasopressor… because more people died when we ran out of norepi and had to use neo.
July 21, 2026 at 2:45 AM
I've seen it used as a last ditch vasopressor like four times in ten years but a lot of folks seem to think taking it has some benefit. I think dyeing your teeth blue to live longer is a dubious proposition.
August 28, 2025 at 9:48 PM
I've seen it used as a last ditch vasopressor like four times in ten years but a lot of folks seem to think taking it has some benefit. I think dyeing your teeth blue to live longer is a dubious proposition.
Hill 9. (more of a hillock) If you have time, site an arterial line before induction – failing that have an assistant keep a finger on the radial pulse and give more vasopressor if it weakens (this is very much second best).
November 17, 2024 at 7:26 PM
Hill 9. (more of a hillock) If you have time, site an arterial line before induction – failing that have an assistant keep a finger on the radial pulse and give more vasopressor if it weakens (this is very much second best).
The value judgments in the #ADAPT trial design are more interesting than the results
I give broad spectrum antibiotics to almost every patient on a vasopressor in the MICU. It’s because I value human life orders of magnitude more than antibiotic “stewardship” in my decision making
I give broad spectrum antibiotics to almost every patient on a vasopressor in the MICU. It’s because I value human life orders of magnitude more than antibiotic “stewardship” in my decision making
This is just ludicrous misvaluation of the relative importance of one day of antibiotics vs a human life
December 10, 2024 at 2:07 AM
The value judgments in the #ADAPT trial design are more interesting than the results
I give broad spectrum antibiotics to almost every patient on a vasopressor in the MICU. It’s because I value human life orders of magnitude more than antibiotic “stewardship” in my decision making
I give broad spectrum antibiotics to almost every patient on a vasopressor in the MICU. It’s because I value human life orders of magnitude more than antibiotic “stewardship” in my decision making
weniger Noradrenalin/Vasopressin ggf. Nitro erwägen (wenn ohne Vasopressor zu hoch)
· In Ordnung? Ab zu Punkt 3
· In Ordnung? Ab zu Punkt 3
September 29, 2023 at 7:09 AM
weniger Noradrenalin/Vasopressin ggf. Nitro erwägen (wenn ohne Vasopressor zu hoch)
· In Ordnung? Ab zu Punkt 3
· In Ordnung? Ab zu Punkt 3
Hill 8. Give a dose of vasopressor with your induction agent in haemodynamically unstable patients (that is most critically ill patients -even the pre-induction hypertensive ones)
a woman 's hand is holding a slice of grapefruit in her right hand
ALT: a woman 's hand is holding a slice of grapefruit in her right hand
media.tenor.com
November 17, 2024 at 7:26 PM
Hill 8. Give a dose of vasopressor with your induction agent in haemodynamically unstable patients (that is most critically ill patients -even the pre-induction hypertensive ones)
Following pandemic-era changes, many ICU outcome measures returned to prior levels. The rates of mechanical ventilation have declined even further, while vasopressor use remained elevated above 2010s rates.
ja.ma/3HiklyV #MedSky
ja.ma/3HiklyV #MedSky
June 1, 2025 at 5:52 PM
Following pandemic-era changes, many ICU outcome measures returned to prior levels. The rates of mechanical ventilation have declined even further, while vasopressor use remained elevated above 2010s rates.
ja.ma/3HiklyV #MedSky
ja.ma/3HiklyV #MedSky
You tell em Raj ...and metaraminol is OUR vasopressor
January 2, 2026 at 9:04 AM
You tell em Raj ...and metaraminol is OUR vasopressor
new systematic review & meta-analysis on peripheral pressors:
"the incidence of adverse events after short-term vasopressor administration through PIV catheters was low… with appropriate monitoring, PIV administration might reduce the need for CVC placement."
in @jamanetworkopen.com
"the incidence of adverse events after short-term vasopressor administration through PIV catheters was low… with appropriate monitoring, PIV administration might reduce the need for CVC placement."
in @jamanetworkopen.com
Incidence of Adverse Events in Peripheral Intravenous Vasopressor Use
This systematic review and meta-analysis examines incidence of adverse events and central venous catheter avoidance after peripheral intravenous administration of vasopressors in adults with hypotensi...
jamanetwork.com
March 16, 2026 at 5:19 PM
new systematic review & meta-analysis on peripheral pressors:
"the incidence of adverse events after short-term vasopressor administration through PIV catheters was low… with appropriate monitoring, PIV administration might reduce the need for CVC placement."
in @jamanetworkopen.com
"the incidence of adverse events after short-term vasopressor administration through PIV catheters was low… with appropriate monitoring, PIV administration might reduce the need for CVC placement."
in @jamanetworkopen.com
Oral blood pressure augmenting agents for intravenous vasopressor weaning
CCR Journal Watch
criticalcarereviews.com/latest-evide...
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe criticalcarereviews.com/newsletters/...
CCR Journal Watch
criticalcarereviews.com/latest-evide...
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe criticalcarereviews.com/newsletters/...
December 28, 2024 at 9:27 PM
Oral blood pressure augmenting agents for intravenous vasopressor weaning
CCR Journal Watch
criticalcarereviews.com/latest-evide...
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe criticalcarereviews.com/newsletters/...
CCR Journal Watch
criticalcarereviews.com/latest-evide...
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe criticalcarereviews.com/newsletters/...
Félicitations aux auteurs pour découvrir que plus c'est grave, plus c'est grave
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Association of noradrenaline dose with mortality in critically ill patients: a systematic review and dose-response meta-analysis - Critical Care
Background Noradrenaline is currently the first-line vasopressor in treatment of circulatory failure. Its dose reflects illness severity, and together with dopamine, dobutamine and adrenaline, it is u...
link.springer.com
December 1, 2025 at 1:00 PM
Félicitations aux auteurs pour découvrir que plus c'est grave, plus c'est grave
link.springer.com/article/10.1...
link.springer.com/article/10.1...