Daniel Hoffmann 🌼
@danielhoffmann.eurosky.social
Using quantitative computational modeling as scientific instrument. Prof at Uni Duisburg-Essen. Science & art addict. Posts my own.
#computationalmodeling #bayes #quantitativebiology #immunesystem #cancer #infections #education #HTseq #art #poetry
#computationalmodeling #bayes #quantitativebiology #immunesystem #cancer #infections #education #HTseq #art #poetry
If the article below holds water this could make the Internet completely unusable, a habitat for unstoppable digital pathogens.
www.theguardian.com/technology/2...
#ai #internet
www.theguardian.com/technology/2...
#ai #internet
AI in your oven? Anthropic warns models ‘months away’ from self-replication on smart devices
Researchers say ‘AI worms’ could soon infiltrate internet-connected devices amid calls for increased guardrails
www.theguardian.com
October 14, 2026 at 7:05 AM
If the article below holds water this could make the Internet completely unusable, a habitat for unstoppable digital pathogens.
www.theguardian.com/technology/2...
#ai #internet
www.theguardian.com/technology/2...
#ai #internet
Naivety and profundity: some thoughts on the #poetry of #EmilyDickinson and #MaschaKaleko.
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Daniel Hoffmann 🌼 (@[email protected])
For #poetry lovers: On the surface, naivety and profundity seem to be mutually exclusive but actually they are not (simple example: many questions by children). This could be one reason for why people...
mathstodon.xyz
October 13, 2026 at 9:28 PM
Naivety and profundity: some thoughts on the #poetry of #EmilyDickinson and #MaschaKaleko.
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Would you enroll your baby in this study in a region with high prevalence of hepatitis B? Would you play Russian roulette with your baby?
www.theguardian.com/society/2026...
#hbv #hepatitisb #vaccines
www.theguardian.com/society/2026...
#hbv #hepatitisb #vaccines
Controversial vaccine trial touted by RFK Jr gets go-ahead in Guinea-Bissau
Recommended dose of hepatitis B vaccine will be withheld from thousands of newborns by Danish researchers
www.theguardian.com
October 10, 2026 at 7:18 AM
Would you enroll your baby in this study in a region with high prevalence of hepatitis B? Would you play Russian roulette with your baby?
www.theguardian.com/society/2026...
#hbv #hepatitisb #vaccines
www.theguardian.com/society/2026...
#hbv #hepatitisb #vaccines
Quantitative analysis of adaptive immunity: Immensely proud of this paper in eLife:
doi.org/10.7554/eLif...
More at:
mathstodon.xyz/@Daniel_Hoff...
doi.org/10.7554/eLif...
More at:
mathstodon.xyz/@Daniel_Hoff...
Client Challenge
doi.org
October 6, 2026 at 7:48 AM
Quantitative analysis of adaptive immunity: Immensely proud of this paper in eLife:
doi.org/10.7554/eLif...
More at:
mathstodon.xyz/@Daniel_Hoff...
doi.org/10.7554/eLif...
More at:
mathstodon.xyz/@Daniel_Hoff...
New version of my free ebook / textbook "Quantitative Concepts for Biologists", now with chapter 10 on Common Statistics Problems
doi.org/10.5281/zeno...
#biology #textbook #biostatistics #reproducibility #quantitativebiology
doi.org/10.5281/zeno...
#biology #textbook #biostatistics #reproducibility #quantitativebiology
Quantitative Concepts for Biologists
An introductory course on quantitative concepts in biology for students in biology and natural sciences.
doi.org
September 25, 2026 at 12:47 PM
New version of my free ebook / textbook "Quantitative Concepts for Biologists", now with chapter 10 on Common Statistics Problems
doi.org/10.5281/zeno...
#biology #textbook #biostatistics #reproducibility #quantitativebiology
doi.org/10.5281/zeno...
#biology #textbook #biostatistics #reproducibility #quantitativebiology
Planetary health check 2026, a fact-based summary that deserves to be read widely. Still better than Mars, but working on it. www.planetaryhealthcheck.org#reports-sect...
#planet #climatecrisis
#planet #climatecrisis
Planetary Health Check
We have breached 7 out of 9 Planetary Boundaries.The Planetary Health Check 2026 makes it clear: We have to act now.
www.planetaryhealthcheck.org
September 22, 2026 at 6:28 AM
Planetary health check 2026, a fact-based summary that deserves to be read widely. Still better than Mars, but working on it. www.planetaryhealthcheck.org#reports-sect...
#planet #climatecrisis
#planet #climatecrisis
Book recommendation: Victor Klemperers "The Language of the Third Reich: A Philologist's Notebook"
mathstodon.xyz/@Daniel_Hoff...
#books #language #totalitarianism
mathstodon.xyz/@Daniel_Hoff...
#books #language #totalitarianism
Daniel Hoffmann 🌼 (@[email protected])
Book recommendation: Victor Klemperers "The Language of the Third Reich: A Philologist's Notebook" is a readable monument of living in a totalitarian state. He describes how language, individuals, and...
mathstodon.xyz
September 13, 2026 at 12:10 PM
Book recommendation: Victor Klemperers "The Language of the Third Reich: A Philologist's Notebook"
mathstodon.xyz/@Daniel_Hoff...
#books #language #totalitarianism
mathstodon.xyz/@Daniel_Hoff...
#books #language #totalitarianism
mathstodon.xyz/@Daniel_Hoff...
More than 16000 heat-associated fatalities in Germany this year. Seems like an outlier but is in agreement with the trend.
#heatwaves #climatecrisis
More than 16000 heat-associated fatalities in Germany this year. Seems like an outlier but is in agreement with the trend.
#heatwaves #climatecrisis
Daniel Hoffmann 🌼 (@[email protected])
Attached: 1 image
With about 16000 deaths, this year's heatwaves were the deadliest natural disaster in Germany for at least the last 100 years (https://www.sueddeutsche.de/projekte/artikel/wissen/so...
mathstodon.xyz
September 12, 2026 at 1:16 PM
mathstodon.xyz/@Daniel_Hoff...
More than 16000 heat-associated fatalities in Germany this year. Seems like an outlier but is in agreement with the trend.
#heatwaves #climatecrisis
More than 16000 heat-associated fatalities in Germany this year. Seems like an outlier but is in agreement with the trend.
#heatwaves #climatecrisis
Tick-borne virus: Virtually the whole biosphere is constrained by basic parameters such as temperature, which is why the #ClimateCrisis affects all life. One example that should be known more widely is the spread of deadly #infections with shifting climate zones:
www.science.org/content/arti...
www.science.org/content/arti...
Deadly tick-borne virus gains ground in Europe as climate warms
Kosovo shows how surveillance can uncover hidden circulation—and help countries prepare before human cases appear
www.science.org
August 29, 2026 at 7:45 AM
Tick-borne virus: Virtually the whole biosphere is constrained by basic parameters such as temperature, which is why the #ClimateCrisis affects all life. One example that should be known more widely is the spread of deadly #infections with shifting climate zones:
www.science.org/content/arti...
www.science.org/content/arti...
I am mildly obsessed with #poetry, which can be an ingenious way of making experience portable by the music of language. Though, I still don't know what a poem is, the concept has no clear boundaries.
What is a poem?
Today in the mail:
a heart, wrapped in paper,
red, warm, words beating.
#haiku
What is a poem?
Today in the mail:
a heart, wrapped in paper,
red, warm, words beating.
#haiku
August 25, 2026 at 2:20 PM
Mini-essay on "Disrupting the flow of knowledge"
#education #populism #climatecrisis
mathstodon.xyz/@Daniel_Hoff...
#education #populism #climatecrisis
mathstodon.xyz/@Daniel_Hoff...
Daniel Hoffmann 🌼 (@[email protected])
Disrupting the flow of knowledge: A newspaper article with a summary of excess deaths from a heatwave is an excellent example of how we gain important knowledge beyond our immediate experience. Inform...
mathstodon.xyz
August 23, 2026 at 8:12 AM
Mini-essay on "Disrupting the flow of knowledge"
#education #populism #climatecrisis
mathstodon.xyz/@Daniel_Hoff...
#education #populism #climatecrisis
mathstodon.xyz/@Daniel_Hoff...
We are waking up a monster, not in a novel but for real. One of the consequences of the #climatecrisis is the irreversible thawing of #permafrost.
Excellent article: readable & relevant.
www.theguardian.com/environment/...
Excellent article: readable & relevant.
www.theguardian.com/environment/...
The threatening thaw: climate professor on heatwave risks to tipping point of permafrost
Prof Gustaf Hugelius warns wildfires could accelerate release of methane and carbon as vast regions approach irreversible thresholds
www.theguardian.com
August 22, 2026 at 7:05 AM
We are waking up a monster, not in a novel but for real. One of the consequences of the #climatecrisis is the irreversible thawing of #permafrost.
Excellent article: readable & relevant.
www.theguardian.com/environment/...
Excellent article: readable & relevant.
www.theguardian.com/environment/...
Populists in government make people poorer than they would have been otherwise, according to this empirical study.
www.kielinstitut.de/publications...
#economy
www.kielinstitut.de/publications...
#economy
Populist Leaders and the Economy - Kiel Institute
www.kielinstitut.de
August 19, 2026 at 12:52 PM
Populists in government make people poorer than they would have been otherwise, according to this empirical study.
www.kielinstitut.de/publications...
#economy
www.kielinstitut.de/publications...
#economy
What could possibly go wrong with populists in government? Where's the evidence? This is unbearable.
www.theguardian.com/politics/202...
#climatecrisis
www.theguardian.com/politics/202...
#climatecrisis
Reform’s Tice accused of misinformation after urging people to enjoy heatwaves
Backlash from nurses, medical experts and green campaigners in response to deputy leader dismissing efforts to reach net zero
www.theguardian.com
August 19, 2026 at 7:57 AM
What could possibly go wrong with populists in government? Where's the evidence? This is unbearable.
www.theguardian.com/politics/202...
#climatecrisis
www.theguardian.com/politics/202...
#climatecrisis
Newly approved mRNA vaccine against flu works well. Faster development allows better match with dominant seasonal flu strains.
www.nature.com/articles/d41...
#vaccines #flu
www.nature.com/articles/d41...
#vaccines #flu
Will the mRNA flu shot work better than a regular seasonal one? What the science says
Moderna’s newly approved vaccine could allow manufacturers to respond more rapidly to changing influenza strains.
www.nature.com
August 14, 2026 at 6:54 AM
Newly approved mRNA vaccine against flu works well. Faster development allows better match with dominant seasonal flu strains.
www.nature.com/articles/d41...
#vaccines #flu
www.nature.com/articles/d41...
#vaccines #flu
August 10, 2026 at 6:19 AM
Some thoughts on "ecological amnesia":
mathstodon.xyz/@Daniel_Hoff...
Interesting article on the topic:
www.lemonde.fr/idees/articl...
#biodiversity #ecology
mathstodon.xyz/@Daniel_Hoff...
Interesting article on the topic:
www.lemonde.fr/idees/articl...
#biodiversity #ecology
Daniel Hoffmann 🌼 (@[email protected])
"Ecological amnesia" is an interesting concept: ecological degradation may take several generations, so people who have been living only in a degraded environment perceive its degraded state as normal...
mathstodon.xyz
August 9, 2026 at 8:19 AM
Some thoughts on "ecological amnesia":
mathstodon.xyz/@Daniel_Hoff...
Interesting article on the topic:
www.lemonde.fr/idees/articl...
#biodiversity #ecology
mathstodon.xyz/@Daniel_Hoff...
Interesting article on the topic:
www.lemonde.fr/idees/articl...
#biodiversity #ecology
A Titanic counterfactual to illustrate the absurdity of the response to the #ClimateCrisis:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Daniel Hoffmann 🌼 (@[email protected])
The following Titanic counterfactual makes it painfully clear how absurd the reaction to the #ClimateCrisis is: Imagine most of the crew of the Titanic *knew* that the ship was on a collision course w...
mathstodon.xyz
August 5, 2026 at 5:15 PM
A Titanic counterfactual to illustrate the absurdity of the response to the #ClimateCrisis:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Some observations on climate change denial and wildfires:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Daniel Hoffmann 🌼 (@[email protected])
It is interesting to see how climate change deniers spin the wildfires.
1. Global warming does not exist, but if it does it has nothing to do with human activity (like release of greenhouse gases by...
mathstodon.xyz
August 1, 2026 at 6:56 PM
Some observations on climate change denial and wildfires:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Developing AI competences of PhD students in biomedicine:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
Daniel Hoffmann 🌼 (@[email protected])
What AI competences should PhD students in the life sciences / biomedicine acquire today? (Asking for a friend who is developing a curriculum.) I know that it's impossible to answer this question, giv...
mathstodon.xyz
July 21, 2026 at 6:56 PM
Developing AI competences of PhD students in biomedicine:
mathstodon.xyz/@Daniel_Hoff...
mathstodon.xyz/@Daniel_Hoff...
When testing several open-weights LLMs for correcting typos/grammar in a technical LaTeX text, I found that capabilities differ. Most caught simple typos, but only one found this one:
"... with number $k$ of clusters $C_1, C_2, \ldots, C_N$ ..." (the index N should be k).
"... with number $k$ of clusters $C_1, C_2, \ldots, C_N$ ..." (the index N should be k).
July 20, 2026 at 9:19 AM
When testing several open-weights LLMs for correcting typos/grammar in a technical LaTeX text, I found that capabilities differ. Most caught simple typos, but only one found this one:
"... with number $k$ of clusters $C_1, C_2, \ldots, C_N$ ..." (the index N should be k).
"... with number $k$ of clusters $C_1, C_2, \ldots, C_N$ ..." (the index N should be k).
Version of free textbook for biology undergraduates "Quantitative Concepts for Biologists" with many corrections for typos/grammar:
doi.org/10.5281/zeno...
Ran the complete LaTeX source through an open weights LLM and used emacs/ediff to decide on each change.
doi.org/10.5281/zeno...
Ran the complete LaTeX source through an open weights LLM and used emacs/ediff to decide on each change.
Quantitative Concepts for Biologists
An introductory course on quantitative concepts in biology for undergraduates in biology and natural sciences.
doi.org
July 19, 2026 at 12:45 PM
Version of free textbook for biology undergraduates "Quantitative Concepts for Biologists" with many corrections for typos/grammar:
doi.org/10.5281/zeno...
Ran the complete LaTeX source through an open weights LLM and used emacs/ediff to decide on each change.
doi.org/10.5281/zeno...
Ran the complete LaTeX source through an open weights LLM and used emacs/ediff to decide on each change.