Yuki Miura
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ykmiura.bsky.social
Yuki Miura
@ykmiura.bsky.social
Developmental neurobiologist, studying human nervous system assembly, functions and neurological disorders: https://ymiuralab.com/
Reposted by Yuki Miura
🎉 Join us for the 1st NYC Area Pain Research Meet-Up!
🗓 Fri, Dec 5 | 3–6 PM
📍 NYU Pain Research Center, 433 1st Ave
Don’t miss Dr. Steve Davidson’s keynote: “Humanizing Pain Neurobiology for Translational Gain” — plus great company & treats!
See you there! 💫 #PainResearch #NYCScience #Neurobiology
November 11, 2025 at 7:33 PM
Delighted to be part of the PRC community and looking forward to contributing to future collaborations using human cellular model systems!
PRC Highlight: We are excited to #welcome Dr. Yuki Miura as an Associate Member to the PRC. Yuki’s work leverages stem cell–derived organoids and assembloids to model human neural circuits -level disruption contributes to neurological disorders and pain! 🧪🧑‍🔬 #YukiMiura #PRC
September 28, 2025 at 3:49 PM
Reposted by Yuki Miura
First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵
Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma
Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...
rdcu.be
January 8, 2025 at 5:13 PM
Our work uncovering CACNA1G channelopathies in thalamocortical assembloids was featured on the cover of the final 2024 issue of Neuron! A great way to kick off 2025!

Full article here: www.cell.com/neuron/fullt...
January 12, 2025 at 6:52 PM
Reposted by Yuki Miura
Assembloid model “reveals cell & network level defects associated with … perturbations at early, previously inaccessible … stages of thalamocortical crosstalk in human development”
Excellent work by Ji-il Kim @ykmiura.bsky.social Min-Yin Li & @sergiuppasca.bsky.social
www.cell.com/neuron/fullt...
Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
Kim et al. developed a human assembloid to investigate the effects of calcium channel function on the thalamocortical pathway. The M1531V CACNA1G variant altered T-type currents and induced hyperactivity, while CACNA1G loss changed connectivity and thalamic activity. This highlights the utility of assembloids in identifying circuit-level disease phenotypes.
www.cell.com
December 18, 2024 at 7:31 PM