Joan Chang
@tranejoan.bsky.social
Chasing the👩🏻🔬dream: HKG-EDI-LDN-CPH-RDU-MAN| Matrix/⏰ biology | Disease microenvironment | MRC CDA Fellow @mcrcellmatrix.bsky.social @mcf-uom.bsky.social, University of Manchester | Mass Spec aficionado
Pinned
Joan Chang
@tranejoan.bsky.social
· Mar 5
Macrophages promote collagen deposition through circadian regulation of fibroblasts
Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...
www.biorxiv.org
Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out 👇🏻
#macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social
www.biorxiv.org/content/10.1...
#macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social
www.biorxiv.org/content/10.1...
July 3, 2026 at 6:05 AM
The newly minted #RupertTimpl awardee, James Conway, on integrin phosphorylation and presenting really cool native ECM spot array to look at age-related changes in cancer migration. Very well deserved! #MBE2026
July 1, 2026 at 12:21 PM
The newly minted #RupertTimpl awardee, James Conway, on integrin phosphorylation and presenting really cool native ECM spot array to look at age-related changes in cancer migration. Very well deserved! #MBE2026
Reposted by Joan Chang
Workshop #1 at #MBE2026 featured @tranejoan.bsky.social and @collagenyoshi.bsky.social back-to-back: first a wonderful talk on collagen trafficking, then a deep dive into lysine hydroxylation in collagens — asking the important question of how lysyl hydroxylases recognise their specific targets.
June 30, 2026 at 9:05 AM
Workshop #1 at #MBE2026 featured @tranejoan.bsky.social and @collagenyoshi.bsky.social back-to-back: first a wonderful talk on collagen trafficking, then a deep dive into lysine hydroxylation in collagens — asking the important question of how lysyl hydroxylases recognise their specific targets.
What an inspirational talk by Fiona Watt - beautiful data since 1990s, and the fact that something first seen in 1999 is followed up right now!! #MBE2026
June 29, 2026 at 4:44 PM
What an inspirational talk by Fiona Watt - beautiful data since 1990s, and the fact that something first seen in 1999 is followed up right now!! #MBE2026
What a wonderful first #ECR session hosted by @themeshwork.bsky.social! Join in the vibrant community and the future of #ECMatrix is super bright! #MBE2026
June 29, 2026 at 3:54 PM
What a wonderful first #ECR session hosted by @themeshwork.bsky.social! Join in the vibrant community and the future of #ECMatrix is super bright! #MBE2026
We are ready to start #MBE2026!! SHOUT-OUT to @valerioizzi.bsky.social for leading this conference, super excited about the next few days #ECMatrix #ScienceNoBoundaries
June 29, 2026 at 3:07 PM
We are ready to start #MBE2026!! SHOUT-OUT to @valerioizzi.bsky.social for leading this conference, super excited about the next few days #ECMatrix #ScienceNoBoundaries
Reposted by Joan Chang
Guest speaker Joan Chang… taking a break from rainy Manchester to visit Sunny Liverpool…
Circadian rhythms in collagen and tissue repair..
@tranejoan.bsky.social
Circadian rhythms in collagen and tissue repair..
@tranejoan.bsky.social
June 17, 2026 at 9:22 AM
Guest speaker Joan Chang… taking a break from rainy Manchester to visit Sunny Liverpool…
Circadian rhythms in collagen and tissue repair..
@tranejoan.bsky.social
Circadian rhythms in collagen and tissue repair..
@tranejoan.bsky.social
Reposted by Joan Chang
Registration for #MBE2026 is now open!
Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research.
ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network!
More at www.mbe2026.org
Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research.
ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network!
More at www.mbe2026.org
February 25, 2026 at 6:25 PM
Registration for #MBE2026 is now open!
Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research.
ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network!
More at www.mbe2026.org
Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research.
ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network!
More at www.mbe2026.org
Reposted by Joan Chang
👋Meet your presidents is back! We'll kickstart the week w/past presidents (Mon) followed by another PI (Thurs).
Meet Jeff Miner 🥼2022 ASMB President, Prof at Washington University School of Medicine, studying #BasementMembranes and #kidney. Check out the full interview 👉🏻 youtu.be/LX6afqQ-G0k
Meet Jeff Miner 🥼2022 ASMB President, Prof at Washington University School of Medicine, studying #BasementMembranes and #kidney. Check out the full interview 👉🏻 youtu.be/LX6afqQ-G0k
Meet Our Presidents: Jeff Miner
YouTube video by ASMB - American Society for Matrix Biology
youtu.be
February 23, 2026 at 9:58 PM
👋Meet your presidents is back! We'll kickstart the week w/past presidents (Mon) followed by another PI (Thurs).
Meet Jeff Miner 🥼2022 ASMB President, Prof at Washington University School of Medicine, studying #BasementMembranes and #kidney. Check out the full interview 👉🏻 youtu.be/LX6afqQ-G0k
Meet Jeff Miner 🥼2022 ASMB President, Prof at Washington University School of Medicine, studying #BasementMembranes and #kidney. Check out the full interview 👉🏻 youtu.be/LX6afqQ-G0k
Reposted by Joan Chang
Spatial transcriptomics (ST) should be conductive to anyone who has done microscopy in their lives, but it's not! Resolution vs coverage tradeoffs, static workflows, heavy data analysis still plague it...
IT'S TIME TO CHANGE THIS!!
INTRODUCING NaVis
www.biorxiv.org/content/10.6...
IT'S TIME TO CHANGE THIS!!
INTRODUCING NaVis
www.biorxiv.org/content/10.6...
www.biorxiv.org
February 20, 2026 at 6:50 AM
Spatial transcriptomics (ST) should be conductive to anyone who has done microscopy in their lives, but it's not! Resolution vs coverage tradeoffs, static workflows, heavy data analysis still plague it...
IT'S TIME TO CHANGE THIS!!
INTRODUCING NaVis
www.biorxiv.org/content/10.6...
IT'S TIME TO CHANGE THIS!!
INTRODUCING NaVis
www.biorxiv.org/content/10.6...
February 17, 2026 at 9:18 PM
Reposted by Joan Chang
Next up: Douglas Gould, PhD 👁️
2026 President-elect of the ASMB and Professor at the University of California, San Francisco.
His work links ECM biology to vision and disease.
✨ Watch: youtu.be/9S3qPxUEBgg
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
2026 President-elect of the ASMB and Professor at the University of California, San Francisco.
His work links ECM biology to vision and disease.
✨ Watch: youtu.be/9S3qPxUEBgg
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Meet Our Presidents: Doug Gould
YouTube video by ASMB - American Society for Matrix Biology
youtu.be
February 17, 2026 at 2:53 AM
Next up: Douglas Gould, PhD 👁️
2026 President-elect of the ASMB and Professor at the University of California, San Francisco.
His work links ECM biology to vision and disease.
✨ Watch: youtu.be/9S3qPxUEBgg
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
2026 President-elect of the ASMB and Professor at the University of California, San Francisco.
His work links ECM biology to vision and disease.
✨ Watch: youtu.be/9S3qPxUEBgg
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Reposted by Joan Chang
Meet Thomas H. Barker, PhD 🔬
2026 President of the American Society for Matrix Biology and Professor at the University of Virginia.
His lab studies ECM signaling, repair, fibrosis, and regeneration.
👀 Watch his full #ASMB2025 interview youtu.be/Dw_BVGWkI94
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
2026 President of the American Society for Matrix Biology and Professor at the University of Virginia.
His lab studies ECM signaling, repair, fibrosis, and regeneration.
👀 Watch his full #ASMB2025 interview youtu.be/Dw_BVGWkI94
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Meet Our Presidents: Tom Barker
YouTube video by ASMB - American Society for Matrix Biology
youtu.be
February 17, 2026 at 2:50 AM
Meet Thomas H. Barker, PhD 🔬
2026 President of the American Society for Matrix Biology and Professor at the University of Virginia.
His lab studies ECM signaling, repair, fibrosis, and regeneration.
👀 Watch his full #ASMB2025 interview youtu.be/Dw_BVGWkI94
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
2026 President of the American Society for Matrix Biology and Professor at the University of Virginia.
His lab studies ECM signaling, repair, fibrosis, and regeneration.
👀 Watch his full #ASMB2025 interview youtu.be/Dw_BVGWkI94
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Reposted by Joan Chang
Say hello to Ambra Pozzi, PhD 🧬
Past President of the #ASMB, whose leadership helped shape the community we celebrate in our #ASMB2025 interview series.
🎥 Watch the full interview: youtu.be/7Ys0rsieCiE
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Past President of the #ASMB, whose leadership helped shape the community we celebrate in our #ASMB2025 interview series.
🎥 Watch the full interview: youtu.be/7Ys0rsieCiE
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Meet Our Presidents: Ambra Pozzi
YouTube video by ASMB - American Society for Matrix Biology
youtu.be
February 17, 2026 at 2:44 AM
Say hello to Ambra Pozzi, PhD 🧬
Past President of the #ASMB, whose leadership helped shape the community we celebrate in our #ASMB2025 interview series.
🎥 Watch the full interview: youtu.be/7Ys0rsieCiE
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Past President of the #ASMB, whose leadership helped shape the community we celebrate in our #ASMB2025 interview series.
🎥 Watch the full interview: youtu.be/7Ys0rsieCiE
#MEETTHEPRESIDENTS #ECM #MATRIXBIOLOGY
Reposted by Joan Chang
We're excited to share our latest publication on immune dysfunction in refractory MG! Huge shoutout to the brilliant clinical scientist @katycdodd.bsky.social - from patient recruitment across the country to experiments and data analysis, you did it all! Can't wait to see what you do next 🌟
February 17, 2026 at 11:16 AM
We're excited to share our latest publication on immune dysfunction in refractory MG! Huge shoutout to the brilliant clinical scientist @katycdodd.bsky.social - from patient recruitment across the country to experiments and data analysis, you did it all! Can't wait to see what you do next 🌟
Happy Chinese New Year!
February 17, 2026 at 11:35 AM
Happy Chinese New Year!
Reposted by Joan Chang
📣Wondering what to expect from our next annual meeting? Planning your journey? Our preliminary program is now live! Don't forget to submit your abstracts!!! #matrixbiology @dsmb-dk.bsky.social @mbsanz.bsky.social @amsocmatbio.bsky.social @themeshwork.bsky.social
www.matrixbiologie.de/annual-meeti...
www.matrixbiologie.de/annual-meeti...
Annual Meeting 2026 - DGMB
www.matrixbiologie.de
February 5, 2026 at 10:40 AM
📣Wondering what to expect from our next annual meeting? Planning your journey? Our preliminary program is now live! Don't forget to submit your abstracts!!! #matrixbiology @dsmb-dk.bsky.social @mbsanz.bsky.social @amsocmatbio.bsky.social @themeshwork.bsky.social
www.matrixbiologie.de/annual-meeti...
www.matrixbiologie.de/annual-meeti...
Had a wonderful time as usual! Really fantastic to see so many new #ECMatrix young scientists from diverse institutions, with exciting projects 💪🏻 and superb hosting (and organisation) from @ccstorytime.bsky.social of course (should've taken more food photos)!
Day 2 of the Matrix Biology PhD course and we’re in the new Fælleshuset building starting our group work brain storming. Thanks to @douglaspdyer.bsky.social and @tranejoan.bsky.social for laying the foundations of ECM biology in yesterday’s lectures!
November 6, 2025 at 8:19 AM
Had a wonderful time as usual! Really fantastic to see so many new #ECMatrix young scientists from diverse institutions, with exciting projects 💪🏻 and superb hosting (and organisation) from @ccstorytime.bsky.social of course (should've taken more food photos)!
📢 2 very exciting PhD opportunities, please share!
We use a range of technologies+systems to study #collagen, #ECMatrix, and #fibrosis 👇
1) MRC CASE DTP - #3D #biomaterials, #immune cells alter, #drugscreens
lnkd.in/e6eMqs8M
2) Bicentenary - #macrophages, #circadian, #omics.
lnkd.in/ekZfJfsd
We use a range of technologies+systems to study #collagen, #ECMatrix, and #fibrosis 👇
1) MRC CASE DTP - #3D #biomaterials, #immune cells alter, #drugscreens
lnkd.in/e6eMqs8M
2) Bicentenary - #macrophages, #circadian, #omics.
lnkd.in/ekZfJfsd
October 20, 2025 at 8:41 AM
📢 2 very exciting PhD opportunities, please share!
We use a range of technologies+systems to study #collagen, #ECMatrix, and #fibrosis 👇
1) MRC CASE DTP - #3D #biomaterials, #immune cells alter, #drugscreens
lnkd.in/e6eMqs8M
2) Bicentenary - #macrophages, #circadian, #omics.
lnkd.in/ekZfJfsd
We use a range of technologies+systems to study #collagen, #ECMatrix, and #fibrosis 👇
1) MRC CASE DTP - #3D #biomaterials, #immune cells alter, #drugscreens
lnkd.in/e6eMqs8M
2) Bicentenary - #macrophages, #circadian, #omics.
lnkd.in/ekZfJfsd
My office for the next week or so, good to be back at HKU.
October 20, 2025 at 3:07 AM
My office for the next week or so, good to be back at HKU.
Reposted by Joan Chang
Looking for a PhD ? Don’t miss ⬇️
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
October 4, 2025 at 9:31 AM
Looking for a PhD ? Don’t miss ⬇️
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases
Reposted by Joan Chang
Thoughtful (and hopeful) reflections on the state-of-play for #ResearchCulture assessment as part of #REF2029 and the #REFPCE indicators project:
wonkhe.com/blogs/is-res...
"We don’t need all the answers for 2029, but we shouldn’t discard the tangible progress made"
wonkhe.com/blogs/is-res...
"We don’t need all the answers for 2029, but we shouldn’t discard the tangible progress made"
Is research culture really too hard to assess?
Yolana Pringle and Ben Tatler make the case that the REF pause should be the moment to build on the most substantial sector-wide collaboration ever undertaken on research environments
wonkhe.com
October 1, 2025 at 3:33 PM
Thoughtful (and hopeful) reflections on the state-of-play for #ResearchCulture assessment as part of #REF2029 and the #REFPCE indicators project:
wonkhe.com/blogs/is-res...
"We don’t need all the answers for 2029, but we shouldn’t discard the tangible progress made"
wonkhe.com/blogs/is-res...
"We don’t need all the answers for 2029, but we shouldn’t discard the tangible progress made"
Reposted by Joan Chang
Become part of our new MRC Centre, working across Manchester and Oxford to solve a major challenge of our time - how does the immune system become dysregulated by environmental exposures to cause chronic disease.
www.manchester.ac.uk/exposome-jobs
@exposomeimmunology.bsky.social
www.manchester.ac.uk/exposome-jobs
@exposomeimmunology.bsky.social
www.bmh.manchester.ac.uk
September 30, 2025 at 10:57 AM
Become part of our new MRC Centre, working across Manchester and Oxford to solve a major challenge of our time - how does the immune system become dysregulated by environmental exposures to cause chronic disease.
www.manchester.ac.uk/exposome-jobs
@exposomeimmunology.bsky.social
www.manchester.ac.uk/exposome-jobs
@exposomeimmunology.bsky.social
Reposted by Joan Chang
The liver #transcriptome is highly sensitive to metabolic cues. By characterizing nuclear protein #OGlcNAcylation in mouse #liver during the day, @joanna-chiu.bsky.social &co show how shifts in a nutrient-sensitive #PTM may shape transcriptional regulation @plosbiology.org 🧪 plos.io/3KuS7m1
September 29, 2025 at 1:15 PM
The liver #transcriptome is highly sensitive to metabolic cues. By characterizing nuclear protein #OGlcNAcylation in mouse #liver during the day, @joanna-chiu.bsky.social &co show how shifts in a nutrient-sensitive #PTM may shape transcriptional regulation @plosbiology.org 🧪 plos.io/3KuS7m1