Researchers found that boosting astrocytes helped remove beta-amyloid plaques and preserve cognitive function in Alzheimer's mouse models. The discovery is promising, but human studies are still needed.
DOI: 10.1038/s41593-025-02115-w
DOI: 10.1038/s41593-025-02115-w
November 1, 2026 at 6:00 PM
Researchers found that boosting astrocytes helped remove beta-amyloid plaques and preserve cognitive function in Alzheimer's mouse models. The discovery is promising, but human studies are still needed.
DOI: 10.1038/s41593-025-02115-w
DOI: 10.1038/s41593-025-02115-w
CRN Team Vangheluwe found that cholesterol build-up in APOE4 astrocytes impairs α-synuclein clearance and promotes pathology in human "miBrain" models.
🔗 Read the #publication: bit.ly/4ju4pL7
🔗 Read the #publication: bit.ly/4ju4pL7
November 2, 2026 at 4:18 PM
CRN Team Vangheluwe found that cholesterol build-up in APOE4 astrocytes impairs α-synuclein clearance and promotes pathology in human "miBrain" models.
🔗 Read the #publication: bit.ly/4ju4pL7
🔗 Read the #publication: bit.ly/4ju4pL7
Ok. What are astrocytes, and how do you boost them?
November 1, 2026 at 9:31 PM
Ok. What are astrocytes, and how do you boost them?
Correction : mTORC1 et réactivité des astrocytes dans la sclérose tubéreuse
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Correction : mTORC1 et réactivité des astrocytes dans la sclérose tubéreuse
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abestit.fr
November 2, 2026 at 8:22 PM
Correction : mTORC1 et réactivité des astrocytes dans la sclérose tubéreuse
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On Friday, October 30, at noon, as part of our #radiology #research forum: "Astrocytes Connect Specific Brain Regions Through Plastic Networks," w/ @melcooperphd.bsky.social, postdoctoral fellow at NYU Grossman School of Medicine.
Talk details: cbiweb.net/radiology-re...
#MRI #Neuroscience
Talk details: cbiweb.net/radiology-re...
#MRI #Neuroscience
October 30, 2026 at 3:59 PM
On Friday, October 30, at noon, as part of our #radiology #research forum: "Astrocytes Connect Specific Brain Regions Through Plastic Networks," w/ @melcooperphd.bsky.social, postdoctoral fellow at NYU Grossman School of Medicine.
Talk details: cbiweb.net/radiology-re...
#MRI #Neuroscience
Talk details: cbiweb.net/radiology-re...
#MRI #Neuroscience
Could brain support cells affect aging elsewhere? FGF13 experiments changed memory, inflammation and tissue markers in mice. How the brain-to-body signal works is still uncertain.
thelifespanbrief.com/2026/10/30/f...
thelifespanbrief.com/2026/10/30/f...
FGF13 in Astrocytes and Systemic Aging in Mice | The Lifespan Brief
FGF13 experiments in mouse astrocytes changed cognition, inflammation and senescence markers. The brain-to-body mechanism and human relevance remain uncertain.
thelifespanbrief.com
October 30, 2026 at 10:54 PM
Could brain support cells affect aging elsewhere? FGF13 experiments changed memory, inflammation and tissue markers in mice. How the brain-to-body signal works is still uncertain.
thelifespanbrief.com/2026/10/30/f...
thelifespanbrief.com/2026/10/30/f...
Our gratitude to Bronze Sponsor 𝐖𝐞𝐫𝐟𝐞𝐧 for supporting the 2027 EMBO Workshop “Astrocytes: From Molecules to Systems”! 🧠🔬
Your support helps bring the astrocyte research community together and make this meeting possible.
We’re grateful to have you on board! 🙌
#EMBOAstrocytes
Your support helps bring the astrocyte research community together and make this meeting possible.
We’re grateful to have you on board! 🙌
#EMBOAstrocytes
November 2, 2026 at 8:59 AM
Our gratitude to Bronze Sponsor 𝐖𝐞𝐫𝐟𝐞𝐧 for supporting the 2027 EMBO Workshop “Astrocytes: From Molecules to Systems”! 🧠🔬
Your support helps bring the astrocyte research community together and make this meeting possible.
We’re grateful to have you on board! 🙌
#EMBOAstrocytes
Your support helps bring the astrocyte research community together and make this meeting possible.
We’re grateful to have you on board! 🙌
#EMBOAstrocytes
Mice exposed to heat stress show 40% greater susceptibility to metabolic dysfunction on an obesogenic diet, linked to increased KLK14 and altered hypothalamic astrocytes. PMID:42019490, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00346-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00346-6
No description available
www.cell.com
October 31, 2026 at 9:00 AM
🌟Application note! Differentiation of induced pluripotent stem cells (iPSCs) into astrocytes > zurl.co/pBF3g
#stemcells #cytokines #astrocytes
#stemcells #cytokines #astrocytes
October 29, 2026 at 8:08 AM
🌟Application note! Differentiation of induced pluripotent stem cells (iPSCs) into astrocytes > zurl.co/pBF3g
#stemcells #cytokines #astrocytes
#stemcells #cytokines #astrocytes
October 29th is #WorldStrokeDay 🧠
After ischemic injury, reactive astrocytes ramp up GFAP, a go-to readout for neuroinflammation in stroke models.
Thanks to every neuroscience & cardiovascular researcher working on stroke research 💙
#Neuroscience #NeuroSky
After ischemic injury, reactive astrocytes ramp up GFAP, a go-to readout for neuroinflammation in stroke models.
Thanks to every neuroscience & cardiovascular researcher working on stroke research 💙
#Neuroscience #NeuroSky
October 29, 2026 at 6:37 PM
October 29th is #WorldStrokeDay 🧠
After ischemic injury, reactive astrocytes ramp up GFAP, a go-to readout for neuroinflammation in stroke models.
Thanks to every neuroscience & cardiovascular researcher working on stroke research 💙
#Neuroscience #NeuroSky
After ischemic injury, reactive astrocytes ramp up GFAP, a go-to readout for neuroinflammation in stroke models.
Thanks to every neuroscience & cardiovascular researcher working on stroke research 💙
#Neuroscience #NeuroSky
The temporal-pattern dependence is the interesting part: if astrocytes are in the loop, a stim protocol tuned only to neurons may be modelling half the circuit.
Mice, though.
Mice, though.
November 2, 2026 at 9:01 AM
The temporal-pattern dependence is the interesting part: if astrocytes are in the loop, a stim protocol tuned only to neurons may be modelling half the circuit.
Mice, though.
Mice, though.
Our gratitude to @Co_Biologists for supporting the 2027 EMBO Workshop “Astrocytes: From Molecules to Systems”! 🧠🔬
Your support for scientific exchange helps create a space where ideas, discoveries, and collaborations can flourish.🌱
#EMBOAstrocytes
Your support for scientific exchange helps create a space where ideas, discoveries, and collaborations can flourish.🌱
#EMBOAstrocytes
November 2, 2026 at 9:05 AM
Our gratitude to @Co_Biologists for supporting the 2027 EMBO Workshop “Astrocytes: From Molecules to Systems”! 🧠🔬
Your support for scientific exchange helps create a space where ideas, discoveries, and collaborations can flourish.🌱
#EMBOAstrocytes
Your support for scientific exchange helps create a space where ideas, discoveries, and collaborations can flourish.🌱
#EMBOAstrocytes
Dementia. Astrocytes are an abundant cell type in the central nervous system (CNS), outnumber neurons by x 5 & tile the entire brain & spinal cord. Provide metabolic support, structural scaffolding & homeostatic defense for neurons, their numerous processes wrap around synapses & blood capillaries.
November 1, 2026 at 11:52 PM
Dementia. Astrocytes are an abundant cell type in the central nervous system (CNS), outnumber neurons by x 5 & tile the entire brain & spinal cord. Provide metabolic support, structural scaffolding & homeostatic defense for neurons, their numerous processes wrap around synapses & blood capillaries.
New month, new #LegacyContent! The November 2025 issue of @AJPathology is now fully free in the #OpenArchive!
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
November 2, 2026 at 8:09 PM
New month, new #LegacyContent! The November 2025 issue of @AJPathology is now fully free in the #OpenArchive!
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Full issue: https://ajp.amjpathol.org/issue/S0002-9440(24)X0012-7
On the cover: Astrocytes engaging with fibrillar amyloid in rTg-D HOM rats with cortical dyshoric vascular amyloid
Online now: An orthogonal Cro/OR3 system reveals an influence of astrocytes on motor neuron positioning
An orthogonal Cro/OR3 system reveals an influence of astrocytes on motor neuron positioning
Biological sciences research methodologies; Model organism; Neuroscience; Techniques in genetics
dlvr.it
October 27, 2026 at 12:34 PM
Online now: An orthogonal Cro/OR3 system reveals an influence of astrocytes on motor neuron positioning
👉🏻 My last article in @towardsdatascience.com , showcasing spatial analysis techniques and brain cells as a study case.
#brain #sapatialanalysis #datascience
towardsdatascience.com/where-a-cell...
#brain #sapatialanalysis #datascience
towardsdatascience.com/where-a-cell...
Where a Cell Sits Matters More Than How Many There Are
Using spatstat raster layers and point process models to ask how neurons, astrocytes and microglia sit relative to each other
towardsdatascience.com
November 3, 2026 at 1:14 PM
👉🏻 My last article in @towardsdatascience.com , showcasing spatial analysis techniques and brain cells as a study case.
#brain #sapatialanalysis #datascience
towardsdatascience.com/where-a-cell...
#brain #sapatialanalysis #datascience
towardsdatascience.com/where-a-cell...
Cholesterol has a job beyond heart health: helping brain cells communicate. 🧠
New research reveals how astrocytes, the brain’s support cells, help control the supply that neurons need. https://bit.ly/3Tzwh64
New research reveals how astrocytes, the brain’s support cells, help control the supply that neurons need. https://bit.ly/3Tzwh64
Brain cells regulate cholesterol to control neuron signaling
WashU Medicine researchers show in a new study that brain cells called astrocytes modulate the supply of cholesterol in the brain to help neurons communicate.
bit.ly
October 28, 2026 at 2:42 AM
Cholesterol has a job beyond heart health: helping brain cells communicate. 🧠
New research reveals how astrocytes, the brain’s support cells, help control the supply that neurons need. https://bit.ly/3Tzwh64
New research reveals how astrocytes, the brain’s support cells, help control the supply that neurons need. https://bit.ly/3Tzwh64
Funny. Your brain's janitors just got drafted. South Carolina Nano-ERASER sneaks anti-PTBP1 antibodies past the blood-brain barrier, turns astrocytes into firing neurons. Two shots, Alzheimer's mice rebuild nests. @physicsworld.bsky.social. *buuurp* Regenerating wetware like a save file.
November 3, 2026 at 11:32 PM
Funny. Your brain's janitors just got drafted. South Carolina Nano-ERASER sneaks anti-PTBP1 antibodies past the blood-brain barrier, turns astrocytes into firing neurons. Two shots, Alzheimer's mice rebuild nests. @physicsworld.bsky.social. *buuurp* Regenerating wetware like a save file.
Check out the October FOCIS editors' choice highlights in Science Immunology🔬
Pairing up to decode recognition: zurl.co/VdA5U
Old dog, new tricks: Astrocytes use the CD40 pathway to propagate neuroinflammation: zurl.co/YphFe
@science.org #FOCIS
Pairing up to decode recognition: zurl.co/VdA5U
Old dog, new tricks: Astrocytes use the CD40 pathway to propagate neuroinflammation: zurl.co/YphFe
@science.org #FOCIS
Old dog with new tricks: SARS-CoV-2 variant–specific B cells complement imprinted memory
Both memory and de novo antibody clones neutralize SARS-CoV-2 variants, but with distinct origins and targets.
www.science.org
October 30, 2026 at 2:53 PM
Check out the October FOCIS editors' choice highlights in Science Immunology🔬
Pairing up to decode recognition: zurl.co/VdA5U
Old dog, new tricks: Astrocytes use the CD40 pathway to propagate neuroinflammation: zurl.co/YphFe
@science.org #FOCIS
Pairing up to decode recognition: zurl.co/VdA5U
Old dog, new tricks: Astrocytes use the CD40 pathway to propagate neuroinflammation: zurl.co/YphFe
@science.org #FOCIS
🧠 A new review by Santiago Canals (@canalslab.bsky.social @neuroalc.bsky.social) and Óscar Herreras (@cncajal-csic.bsky.social) in #JCBFM explores how failure of brain tissue homeostasis may trigger neuronal death after ischemia, highlighting the key role of astrocytes.
🧵1/4
🧵1/4
October 27, 2026 at 11:59 AM
🧠 A new review by Santiago Canals (@canalslab.bsky.social @neuroalc.bsky.social) and Óscar Herreras (@cncajal-csic.bsky.social) in #JCBFM explores how failure of brain tissue homeostasis may trigger neuronal death after ischemia, highlighting the key role of astrocytes.
🧵1/4
🧵1/4
Are you working on astrocyte research? 🧠
@braincomms.bsky.social is inviting proposals for a collection on Astrocytes in Neuropsychiatry. Submit your work to highlight how this area of research is transforming the next generation of therapeutic approaches ✍️
oxford.ly/3Wdi8MH
@braincomms.bsky.social is inviting proposals for a collection on Astrocytes in Neuropsychiatry. Submit your work to highlight how this area of research is transforming the next generation of therapeutic approaches ✍️
oxford.ly/3Wdi8MH
October 28, 2026 at 6:00 PM
Are you working on astrocyte research? 🧠
@braincomms.bsky.social is inviting proposals for a collection on Astrocytes in Neuropsychiatry. Submit your work to highlight how this area of research is transforming the next generation of therapeutic approaches ✍️
oxford.ly/3Wdi8MH
@braincomms.bsky.social is inviting proposals for a collection on Astrocytes in Neuropsychiatry. Submit your work to highlight how this area of research is transforming the next generation of therapeutic approaches ✍️
oxford.ly/3Wdi8MH
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice.
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
An Astrocytic Factor Slows Whole-Body Aging in Mice | Lifespan Research Institute
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice. A factor from a well-known family FGFs are signaling molecules that share structural and functional commonalities and play crucial roles in biology, including neural function [1]. Some of these molecules are secreted, and
lifespan.io
October 30, 2026 at 8:00 PM
In Aging Cell, researchers have described how increasing fibroblast growth factor 13 (FGF13) in astrocytes reduces aging throughout the bodies of mice.
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
👉 Read more: https://lifespan.io/an-astrocytic-factor-slows-whole-body-aging-in-mice/
RRIDs were included in this in Nature paper. RRIDs improve reproducibility in scientific research. #methodsmatter #accelerateopenscience #OpenScience
CD51 delineates functionally distinct astrocyte subtypes in neural circuits - Nature
CD51+ astrocytes promote synapse formation in the developing cortex, circuit plasticity in the hippocampus and circuit remodelling after stroke.
doi.org
October 30, 2026 at 7:08 AM
RRIDs were included in this in Nature paper. RRIDs improve reproducibility in scientific research. #methodsmatter #accelerateopenscience #OpenScience
The research performed a systematic analysis of MCell, STEPS, NeuroRD, and NEURON by applying identical calcium diffusion and calcium–calmodulin reaction–diffusion models to various spatial domains of astroglial structures.
#Astrocytes #CalciumDiffusion #Simulation
#Astrocytes #CalciumDiffusion #Simulation
Research reveals limitations of four simulators for glial cell geometries
Source: PLOS Computational Biology
realfeedapp.com
October 29, 2026 at 11:20 AM
The research performed a systematic analysis of MCell, STEPS, NeuroRD, and NEURON by applying identical calcium diffusion and calcium–calmodulin reaction–diffusion models to various spatial domains of astroglial structures.
#Astrocytes #CalciumDiffusion #Simulation
#Astrocytes #CalciumDiffusion #Simulation