Mono- and polyubiquitin suppress condensation of both wild-type Tau-F and Tau-F(P301L), while enhancing the liquid-like properties of the condensates that persist.
#LLPS #Biocondensates
#LLPS #Biocondensates
October 26, 2026 at 9:12 AM
Mono- and polyubiquitin suppress condensation of both wild-type Tau-F and Tau-F(P301L), while enhancing the liquid-like properties of the condensates that persist.
#LLPS #Biocondensates
#LLPS #Biocondensates
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://genesdev.cshlp.org/content/40/17-18/1408.abstract
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
By López-Palacios et al., and Joshua L. Andersen
➡️ https://genesdev.cshlp.org/content/40/17-18/1408.abstract
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
September 3, 2026 at 6:00 PM
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://genesdev.cshlp.org/content/40/17-18/1408.abstract
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
By López-Palacios et al., and Joshua L. Andersen
➡️ https://genesdev.cshlp.org/content/40/17-18/1408.abstract
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://ow.ly/ljPI50ZFk2g
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://ow.ly/ljPI50ZFk2g
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
August 26, 2026 at 3:00 PM
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://ow.ly/ljPI50ZFk2g
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
RESEARCH PAPER: TNK1 is a targetable JAK-independent driver of STAT signaling and inflammation
By López-Palacios et al., and Joshua L. Andersen
➡️ https://ow.ly/ljPI50ZFk2g
Huntsman Cancer Institute
#STAT1 #kinase #inflammation #phaseseparation #biocondensates #IDR
Happy to share our latest work: Fast assembly and in vivo coalescence of ParBf biocondensates involved in bacterial DNA partition
academic.oup.com/nar/article/...
Great thanks to all contributing authors and in particular Perrine Revoil and Linda Delimi for their fruitful collaborative interactions
academic.oup.com/nar/article/...
Great thanks to all contributing authors and in particular Perrine Revoil and Linda Delimi for their fruitful collaborative interactions
Fast assembly and in vivo coalescence of ParBF biocondensates involved in bacterial DNA partition
Abstract. Faithful DNA segregation in bacteria relies on ParABS systems, in which ParB assembles into condensates at centromere-like parS sites, while the
academic.oup.com
August 10, 2026 at 12:33 PM
Happy to share our latest work: Fast assembly and in vivo coalescence of ParBf biocondensates involved in bacterial DNA partition
academic.oup.com/nar/article/...
Great thanks to all contributing authors and in particular Perrine Revoil and Linda Delimi for their fruitful collaborative interactions
academic.oup.com/nar/article/...
Great thanks to all contributing authors and in particular Perrine Revoil and Linda Delimi for their fruitful collaborative interactions
🎉 Congrats to C-SPIRIT Member Sue Rhee (@rheelab.bsky.social) & her colleagues on their new paper in New Phytologist!
🧬They explore metabolic biocondensates that boost efficiency & stress response, aligned with our mission for resilient, sustainable crops
📖: doi.org/10.1111/nph....
#plantscience
🧬They explore metabolic biocondensates that boost efficiency & stress response, aligned with our mission for resilient, sustainable crops
📖: doi.org/10.1111/nph....
#plantscience
August 27, 2025 at 8:56 PM
🎉 Congrats to C-SPIRIT Member Sue Rhee (@rheelab.bsky.social) & her colleagues on their new paper in New Phytologist!
🧬They explore metabolic biocondensates that boost efficiency & stress response, aligned with our mission for resilient, sustainable crops
📖: doi.org/10.1111/nph....
#plantscience
🧬They explore metabolic biocondensates that boost efficiency & stress response, aligned with our mission for resilient, sustainable crops
📖: doi.org/10.1111/nph....
#plantscience
OUTLOOK: Making order from disorder in the nucleolus
By Susan J. Baserga
➡️ https://genesdev.cshlp.org/content/40/5-6/285.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/5-6/351.full
@susanbaserga.bsky.social
#ribonucleoproteins #biocondensates #Cajalbodies #proteininteractions
By Susan J. Baserga
➡️ https://genesdev.cshlp.org/content/40/5-6/285.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/5-6/351.full
@susanbaserga.bsky.social
#ribonucleoproteins #biocondensates #Cajalbodies #proteininteractions
March 19, 2026 at 6:00 PM
OUTLOOK: Making order from disorder in the nucleolus
By Susan J. Baserga
➡️ https://genesdev.cshlp.org/content/40/5-6/285.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/5-6/351.full
@susanbaserga.bsky.social
#ribonucleoproteins #biocondensates #Cajalbodies #proteininteractions
By Susan J. Baserga
➡️ https://genesdev.cshlp.org/content/40/5-6/285.full
Also read:
➡️ https://genesdev.cshlp.org/content/40/5-6/351.full
@susanbaserga.bsky.social
#ribonucleoproteins #biocondensates #Cajalbodies #proteininteractions
Cellular view of metabolism: metabolic biomolecular condensates - Saldivar - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/...
Cellular view of metabolism: metabolic biomolecular condensates
Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology. Biocondensates are membraneless organelles th...
nph.onlinelibrary.wiley.com
August 23, 2025 at 2:57 PM
Cellular view of metabolism: metabolic biomolecular condensates - Saldivar - New Phytologist - Wiley Online Library nph.onlinelibrary.wiley.com/doi/10.1111/...
Excited to share our new preprint on ParB biocondensates!
November 7, 2025 at 8:31 AM
Excited to share our new preprint on ParB biocondensates!
RRIDs were included in this in The Journal of Physical Chemistry Letters paper. We value the author's support of reproducibility. #methodsmatter #RRID #ReproducibleResearch
Chain Length as a Molecular Determinant of Hydrogen-Bond Dynamics in Biocondensates
Read the full paper: Chain Length as a Molecular Determinant of Hydrogen-Bond Dynamics in Biocondensates
doi.org
July 8, 2026 at 7:01 AM
RRIDs were included in this in The Journal of Physical Chemistry Letters paper. We value the author's support of reproducibility. #methodsmatter #RRID #ReproducibleResearch
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #accelerateopenscience #reproducibility #accelerateopenscience
Beyond Electrostatic Interactions: H-Bond Dynamics in Arginine- versus Lysine-Rich Biocondensates
doi.org
September 4, 2025 at 7:00 AM
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #accelerateopenscience #reproducibility #accelerateopenscience
A preprint using: pCAG-NL1AB (RRID:Addgene_15262) from @addgene.bsky.social was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
SynGAP forms biocondensates at sub-micromolar concentrations and recruits PSD95 and receptor oligomers, functioning as a key initiator of PSD formation
www.biorxiv.org
April 26, 2025 at 12:00 PM
A preprint using: pCAG-NL1AB (RRID:Addgene_15262) from @addgene.bsky.social was published.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #methodsmatter #reproducibility
Protein design 2:
-4 helix bundles can create biocondensates, which, with extra functionalising, can be localised in different parts of the cell (A Romanyuk, Bristol)
12/
-4 helix bundles can create biocondensates, which, with extra functionalising, can be localised in different parts of the cell (A Romanyuk, Bristol)
12/
November 28, 2024 at 5:16 PM
Protein design 2:
-4 helix bundles can create biocondensates, which, with extra functionalising, can be localised in different parts of the cell (A Romanyuk, Bristol)
12/
-4 helix bundles can create biocondensates, which, with extra functionalising, can be localised in different parts of the cell (A Romanyuk, Bristol)
12/
#TansleyInsight: Cellular view of #metabolism: metabolic biomolecular condensates
Evan Saldivar, Sterling Field & Seung Rhee 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
Evan Saldivar, Sterling Field & Seung Rhee 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
September 20, 2025 at 1:30 PM
#TansleyInsight: Cellular view of #metabolism: metabolic biomolecular condensates
Evan Saldivar, Sterling Field & Seung Rhee 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
Evan Saldivar, Sterling Field & Seung Rhee 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
(🧵 7/8) Most of this work addresses metabolic biocondensates in bacteria, algae, and animals whose functions are involved in core metabolism relevant to plants, even if their existence as metabolic condensates has not yet been described in plants.
September 9, 2025 at 10:01 AM
(🧵 7/8) Most of this work addresses metabolic biocondensates in bacteria, algae, and animals whose functions are involved in core metabolism relevant to plants, even if their existence as metabolic condensates has not yet been described in plants.
(🧵 6/8) Biocondensates have been identified in molecular pathways ranging from RNA regulation to metabolism to seed germination in plants (Field et al., 2023). In this review, the authors focus on biocondensates that control metabolism.
September 9, 2025 at 10:01 AM
(🧵 6/8) Biocondensates have been identified in molecular pathways ranging from RNA regulation to metabolism to seed germination in plants (Field et al., 2023). In this review, the authors focus on biocondensates that control metabolism.
(🧵 5/8) Biocondensates are membraneless organelles that compartmentalize cellular processes and allow regulatory control of key biomolecules through their assembly and disassembly (Banani et al., 2017).
September 9, 2025 at 10:01 AM
(🧵 5/8) Biocondensates are membraneless organelles that compartmentalize cellular processes and allow regulatory control of key biomolecules through their assembly and disassembly (Banani et al., 2017).
🌱 Abstract 🌱
(🧵 4/8)Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology.
(🧵 4/8)Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology.
September 9, 2025 at 10:01 AM
🌱 Abstract 🌱
(🧵 4/8)Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology.
(🧵 4/8)Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology.
(🧵 2/8) In their Tansley insight, Saldivar et al. highlight the emerging role of metabolic biocondensates – membraneless structures that compartmentalize and regulate metabolic pathways – across diverse biological systems.
September 9, 2025 at 10:01 AM
(🧵 2/8) In their Tansley insight, Saldivar et al. highlight the emerging role of metabolic biocondensates – membraneless structures that compartmentalize and regulate metabolic pathways – across diverse biological systems.
✨ Paper spotlight ✨
(🧵 1/8) Cellular view of metabolism: metabolic biomolecular condensates
nph.onlinelibrary.wiley.com/doi/10.1111/...
(🧵 1/8) Cellular view of metabolism: metabolic biomolecular condensates
nph.onlinelibrary.wiley.com/doi/10.1111/...
September 9, 2025 at 10:01 AM
✨ Paper spotlight ✨
(🧵 1/8) Cellular view of metabolism: metabolic biomolecular condensates
nph.onlinelibrary.wiley.com/doi/10.1111/...
(🧵 1/8) Cellular view of metabolism: metabolic biomolecular condensates
nph.onlinelibrary.wiley.com/doi/10.1111/...
‼️Interesting: Metabolites Shift Equilibria of Biomolecular Condensates.
Enzymatic reactions can regulate biocondensates indirectly by producing and consuming metabolites, even without directly modifying proteins www.biorxiv.org/content/10.6...
Enzymatic reactions can regulate biocondensates indirectly by producing and consuming metabolites, even without directly modifying proteins www.biorxiv.org/content/10.6...
March 21, 2026 at 10:01 PM
‼️Interesting: Metabolites Shift Equilibria of Biomolecular Condensates.
Enzymatic reactions can regulate biocondensates indirectly by producing and consuming metabolites, even without directly modifying proteins www.biorxiv.org/content/10.6...
Enzymatic reactions can regulate biocondensates indirectly by producing and consuming metabolites, even without directly modifying proteins www.biorxiv.org/content/10.6...
Fast assembly and in vivo coalescence of ParB biocondensates involved in bacterial DNA partition https://www.biorxiv.org/content/10.1101/2025.10.27.684735v1
October 27, 2025 at 9:17 PM
Fast assembly and in vivo coalescence of ParB biocondensates involved in bacterial DNA partition https://www.biorxiv.org/content/10.1101/2025.10.27.684735v1
Cellular view of metabolism: metabolic biomolecular condensates nph.onlinelibrary.wiley.com/doi/10.1111/... @newphyt.bsky.social
Cellular view of metabolism: metabolic biomolecular condensates
Recent studies across biological systems highlight an important function of biomolecular condensates (hereafter biocondensates) in regulating physiology. Biocondensates are membraneless organelles th...
nph.onlinelibrary.wiley.com
August 25, 2025 at 3:47 AM
Cellular view of metabolism: metabolic biomolecular condensates nph.onlinelibrary.wiley.com/doi/10.1111/... @newphyt.bsky.social
Stress granule induction in rat retinas damaged by constant LED light. https://www.biorxiv.org/content/10.1101/2024.04.26.591385v1
Stress granule induction in rat retinas damaged by constant LED light. https://www.biorxiv.org/content/10.1101/2024.04.26.591385v1
Objectives: Stress granules (SGs) are cytoplasmic biocondensates formed in response to various cellu
www.biorxiv.org
April 29, 2024 at 4:30 PM
Stress granule induction in rat retinas damaged by constant LED light. https://www.biorxiv.org/content/10.1101/2024.04.26.591385v1
Regulating biocondensates within synthetic cells via segregative phase separation https://www.biorxiv.org/content/10.1101/2024.10.18.619037v1
Regulating biocondensates within synthetic cells via segregative phase separation https://www.biorxiv.org/content/10.1101/2024.10.18.619037v1
Living cells orchestrate a myriad of biological reactions within a highly complex and crowded enviro
www.biorxiv.org
October 20, 2024 at 6:03 AM
Regulating biocondensates within synthetic cells via segregative phase separation https://www.biorxiv.org/content/10.1101/2024.10.18.619037v1