Exciting research in 2018 on naked mole rats found these extraordinary mammals can live up to 30 years and show remarkable resistance to cancer. The study identified unique molecular mechanisms that could revolutionize human health and aging research. #BlackMammalogists #CancerResistance

🥳 Our 7th most downloaded article in 2024:

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities by Bardelli, Russo et. al
https://bit.ly/3CkSE...

#persistercells #DTPs #cancerresistance

@natureportfolio.bsky.social #NRCtop10of2024

Antibody-drug conjugates and beyond in platinum-resistant ovarian cancer: A comprehensive review of emergent strategies

@tamedoncol.bsky.social
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#ADCs #cancerresistance #targetedtherapy #oncology #openaccess

The Naked Mole Rat: Nature’s Immortal Underground Superhero - Forget everything you thought you knew about rodents. The naked mole ... www.myscrappydays.com/news.php?slu... #Nakedmolerat #Nakedmoleratfacts #Heterocephalusglaber #Immortalanimals #Cancerresistance #Painimmunity

Excited that our follow-up paper on LIN28A resistance to imatinib is now posted. We characterized LIN28A small-molecule inhibitors and assessed their effects on cell cycle and apoptosis using phosphoproteomics. #cancerresistance #proteomics www.biorxiv.org/content/10.1...

Bats live surprisingly long lives for their size—some over 40 years—and rarely get cancer. Now, researchers at the University of Rochester are working to uncover why. #BatScience #LongevityResearch #CancerResistance
cosmosmagazine.com/nature/bats-...

NanoString profiling of DNA repair and apoptosis genes in testicular germ cell tumours with divergent chemotherapy outcomes

@tamedoncol.bsky.social
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#testicularcancer #cancerresistance #oncology #openaccess

Researchers are testing a new drug to help fight #cancerResistance to #therapy. #CS18 W-C Lin et al #ScienceAdvances @bcmhouston.bsky.social blogs.bcm.edu/2026/08/13/c...

Recently, our CSO Dr. Ya-Chi Chen was featured in an interview with Bioconjugate Insights, where she shared OBI’s approach to next-generation ADC design.

Read more:
obipharma.com/news/bioconj...

#BispecificAntibodies #DualPayloadADC
#ADC #CancerResistance #NextGenADC

🚨 New Review alert - don't miss this

Strength through diversity: how cancers thrive when clones cooperate

🔓 buff.ly/kQAi97p

#TumourHeterogeneity #TherapyResistance #CancerResistance

🚨 New Review alert - don't miss this

Strength through diversity: how cancers thrive when clones cooperate

🔓 buff.ly/kQAi97p

#TumourHeterogeneity #TherapyResistance #CancerResistance

Evidence for improved DNA repair in long-lived bowhead whale. #DNArepair #BowheadWhaleGenetics #CancerResistance #GeneomeIntegrity @nature.com 🧪🧬
www.nature.com/articles/s41...

Acquired resistance in cancer: towards targeted therapeutic strategies. #CancerResistance #TargetedTherapeutics @natrevcancer.nature.com‬
www.nature.com/articles/s41...

Synapse: Your Connection to our MSK Authors
Meet: Brett Stewart Carver Research Focus: Surgery; Attending
synapse.mskcc.org/synapse/work...

Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers

#ProstateCancer #CancerResistance
#AKTpathway

🔥Hot Off the Press | Unlocking the Secret to #Longevity & #CancerResistance
The bowhead #whale lives over 200 years, defying Peto’s Paradox.Enhanced #DNARepair, driven by #CIRBP, helps prevent cancer by fixing #mutations.Explains its long, cancer-free life. www.nature.com/articles/s41...