#CircAHA
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haoyin.bsky.social
#PeripheralArteryDisease
CLEAR Outcomes trial post-hoc

Bempedoic acid reduces Major Adverse Cardiovascular Events & Major Adverse Limb Events

In 1624 with baseline PAD, 282 MALEs in 41 mo f/up

Absolute risk reduction 2.5% 8.3%➡️5.8%

♂️♀️?🤓

#CircAHA 2026
www.ahajournals.org/doi/10.1161/...
August 20, 2026 at 12:36 PM
mfnavedo.bsky.social
💊Check this out! Using human iPSC-derived sinoatrial node cells & 3D organoids, new study @CircAHA reveals how GLP1 directly accelerates the heart’s pacemaker.

Collab with Lulu Ren (former @mcipucd.bsky.social) & Joe Wu's Lab

@ucdavis.bsky.social

www.ahajournals.org/doi/10.1161/...
Tirzepatide Regulates Pacemaker Function by Modulating cAMP and Calcium Dynamics in Human Sinoatrial Node Cells | Circulation
www.ahajournals.org
June 23, 2026 at 2:45 PM
haoyin.bsky.social
CDK4/6
Endothelial Cell Cycle
#ArterioVenousMalformation
#HereditaryHemorrhagicTelangiectasia

Evidence from
👉Fucci2🐭 (fluorescent cell cycle reporter) Retina +BMP9/10 blocking Ab
+Palbociclib CDK4/6i

👉🐭EC ALK1 KO👁️🧠
+Palbociclib
👉👤HHT2 Skin biopsy

#CircAHA 2024
www.ahajournals.org/doi/full/10....
June 11, 2026 at 12:08 PM
haoyin.bsky.social
Quantitative assessment of #Hypertension & Blood Pressure as a risk for #AorticDissection at Population level

J-SHC >500k, 4 y f/up, 84 events -AD mortality
UK Biobank >500k, 9 y f/up, 182 events -AD incidence
+Meta-analysis 6 prev studies

#AortaEd
#CircAHA 2021
www.ahajournals.org/doi/10.1161/...
April 23, 2026 at 6:47 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @NEJM and @CircAHA #ACC26

https://www.ahajournals.org/circ/nejm-circulation-collaboration
March 30, 2026 at 4:43 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @NEJM and @CircAHA #ACC26

https://www.ahajournals.org/circ/nejm-circulation-collaboration
March 29, 2026 at 9:43 PM
ahajournals.bsky.social
Check out the 2026 Go Red For Women special issues in the #AHAJournals GRFW collection. This year, special issues of @CircAHA, @JAHA_AHA, @StrokeAHA_ASA, and @CircRes spotlight some of the latest research in cardiovascular care in women. #ACC26

https://ahajrnls.org/41aarWz
March 28, 2026 at 9:59 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @NEJM and @CircAHA #ACC26

https://www.ahajournals.org/circ/nejm-circulation-collaboration
March 28, 2026 at 5:18 PM
ahajournals.bsky.social
Meet @CircAHA Editors TOMORROW at #ACC26!
Learn about new and upcoming journal initiatives, gain insight into journal processes, and don't forget to bring your questions for the editors!

Register today: https://ahajrnls.org/3Pz8wbN
March 27, 2026 at 9:57 PM
ahajournals.bsky.social
Check out the 2026 Go Red For Women special issues in the #AHAJournals GRFW collection. This year, special issues of @CircAHA, @JAHA_AHA, @StrokeAHA_ASA, and @CircRes spotlight some of the latest research in cardiovascular care in women. #ACC26

https://ahajrnls.org/41aarWz
March 27, 2026 at 5:04 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @NEJM and @CircAHA #ACC26

https://www.ahajournals.org/circ/nejm-circulation-collaboration
March 27, 2026 at 4:01 PM
haoyin.bsky.social
Lineage tracing of Smooth Muscle Cells of different origins using integrated Dre(ER)-rox-CreER-loxp systems🐭

Second heart field▶️Isl1-Dre::Myh11-RSR-CreER
Cardiac neural crest▶️Wnt1-Dre
Somite▶️Meox1-DreER
Mesothelial/Visceral▶️Upk3b-Dre

Bin Zhou lab @CircAHA 2025
www.ahajournals.org/doi/10.1161/...
January 6, 2026 at 12:25 PM
haoyin.bsky.social
#HutchinsonGilfordProgeriaSyndrome

#SmoothMuscleCell Progerin transgene drives #EndMT #Atherosclerosis🐭

⏫Aortic Endothelial Cell permeability
⏫Lesional EC infiltr▶️ColIV- & TGFβ1-rich plaque😮

Paracrine of progeroid aortic SMC?😆

#CircAHA 2024
www.ahajournals.org/doi/10.1161/...
December 4, 2025 at 11:55 AM
ahajournals.bsky.social
Journal Session @ #AHA25

EHJ and Circulation: Advances in 2025
Featuring Dr. Joseph A. Hill, Dr. Maryjane Farr, and other @CircAHA editors

Saturday 11/8 @ 1:30-2:45pm
Room 210

Add to your schedule: https://ahajrnls.org/43ihSN5
November 8, 2025 at 2:10 PM
ahajournals.bsky.social
Journal Session @ #AHA25

EHJ and Circulation: Advances in 2025
Featuring Dr. Joseph A. Hill, Dr. Maryjane Farr, and other @CircAHA editors

Saturday 11/8 @ 1:30-2:45pm
Room 210

Add to your schedule: https://ahajrnls.org/43ihSN5
November 7, 2025 at 10:25 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @NEJM and @CircAHA #AHA25

https://www.ahajournals.org/circ/nejm-circulation-collaboration
November 6, 2025 at 10:13 PM
ahajournals.bsky.social
Journal Session @ #AHA25

Circulating Global Health Knowledge: Key Findings from AHA Journals
Featuring Editors from #CircAHA, #CircImaging, and more

Fri 11/7 @ 2-3:15pm
Room 243
Add to your schedule: https://ahajrnls.org/4ouw4Lw
November 6, 2025 at 5:55 PM
hadleymd.bsky.social
🤔 Thought-provoking piece in @CircAHA from Kole & Joshi

🫀 A growing group of patients with subclinical atherosclerosis falls in between traditional "primary" and "secondary" prevention. I've heard of "prevention 1.5" or "plaque-informed prevention." How about the following classification system?👇
October 27, 2025 at 10:21 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @nejm.org and #CircAHA

https://www.ahajournals.org/circ/nejm-circulation-collaboration

#TCT2025
October 27, 2025 at 4:31 PM
ahajournals.bsky.social
Exciting news: The #AHAJournals collaboration between @CircAHA and @NEJM is live!

Authors now have the option to select a seamless transfer of their manuscript between NEJM and Circulation. #TCT2025

Learn more: https://ahajrnls.org/4oGZ4Q2
October 26, 2025 at 5:15 PM
ahajournals.bsky.social
Submitting your #cardiology manuscript to NEJM?

Learn more about seamlessly transferring your manuscript between @nejm.org and #CircAHA

https://www.ahajournals.org/circ/nejm-circulation-collaboration

#TCT2025
October 25, 2025 at 9:00 PM
haoyin.bsky.social
Histone Variants
#SmoothMuscleCell

1⃣H2A.Z
⬇️in #Atherosclerosis
⏫SMC contractile gene
#CircAHA 2018
www.ahajournals.org/doi/10.1161/...
#BMCGenom 2025
bmcgenomics.biomedcentral.com/articles/10....

2⃣H3.3B
⬆️in #AorticDissection
⏫SMC synthetic genes
#Genomics 2023
www.sciencedirect.com/science/arti...
October 15, 2025 at 9:16 PM
haoyin.bsky.social
#AllograftVasculopathy

TET2 #DNADemethylase #MethylcytosineDioxygenase, an epigenomic defender of #SmoothMuscleCell contractile phenotype
⏬Interferon IFNγ in SMC

Ascorbic acid
⏫TET2 activity
⏬🐭aortic #GraftArteriopathy

#CircAHA 2021 @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...
September 6, 2025 at 1:32 PM
sonuabrahammd.bsky.social
🚨 New @CircAHA #ESC2025 SimPub alert!
🚨 HCM isn’t just driven by rare Mendelian mutations. This study highlights the role of intermediate-effect variants (IEVs)—variants with moderate effect & low penetrance—in shaping disease expression. #HCM #SoMeEditor

tinyurl.com/HCM-IEVs
Redefining the Genetic Architecture of Hypertrophic Cardiomyopathy: Role of Intermediate Effect Variants | Circulation
Background: Hypertrophic cardiomyopathy (HCM) is a genetically heterogeneous disorder primarily linked to rare variants in sarcomere genes, though recently certain non-sarcomeric genes have emerged as...
tinyurl.com
August 29, 2025 at 2:52 PM
ahajournals.bsky.social
Join the #CircAHA #AHAJournals Editors at #ESCCongress!

Circulation: The Full Spectrum
Sunday, 8/31 @ 17:30 - 18:30

Add it to your program today!: https://ahajrnls.org/47TBD0p
August 29, 2025 at 1:46 PM