#DrugRepositioning
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projectpicked.bsky.social
🚀 New 𝐏𝐈𝐂𝐊𝐄𝐃 publication!

Exploring 𝐜𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐝𝐫𝐮𝐠 𝐫𝐞𝐩𝐨𝐬𝐢𝐭𝐢𝐨𝐧𝐢𝐧𝐠 to tackle 𝐜𝐚𝐫𝐝𝐢𝐨𝐫𝐞𝐧𝐚𝐥 𝐝𝐢𝐬𝐞𝐚𝐬𝐞—integrating 𝐨𝐦𝐢𝐜𝐬, 𝐛𝐢𝐨𝐢𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐜𝐬 & 𝐧𝐞𝐭𝐰𝐨𝐫𝐤 𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠 to find new therapeutic uses.

📖 Read here: DOI: 10.1002/pmic.202400109

#PrecisionMedicine #DrugRepositioning #Bioinformatics #ProjectPICKED
February 20, 2025 at 10:09 AM
delta4ai.bsky.social
Take your drug development pipeline to the next level with Delta4’s AI-powered platform!

💡 Accelerate Efficiency & Speed
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🧬 Gain Valuable Biomarker Insights

Learn more here:
delta4.ai/development-...

#Delta4 #DrugDiscovery #DrugTarget #DrugRepositioning
May 30, 2025 at 9:22 AM
sigtrans-sttt.bsky.social
This study explores how #SexualDimorphism in #COVID19, driven by hormonal regulation of immunity and viral dynamics, guides #DrugRepositioning and host-targeted #Immunotherapy approaches for #ViralPneumonia.
#STTT #OpenAccess: doi.org/10.1038/s413...
Sexual dimorphism of COVID-19 inspires drug repositioning and host-targeting immunotherapy for viral pneumonia
May 2, 2026 at 4:25 PM
delta4ai.bsky.social
Finding the right #compounds for the right #diseases is a key challenge in #DrugRepositioning. Delta4’s Hyper-C platform starts with disease biology to identify promising therapeutic opportunities and provides mechanistic rationales to support development decisions.
Read more: delta4.ai/services/
August 4, 2026 at 11:35 AM
fcp-sfpt.bsky.social
Now available:
When Side Effects Become Therapies: A Mechanistic Taxonomy of Adverse Drug Reactions as Translational Signals for Drug Repositioning
#clinical #pharmacology #taxonomy #DrugRepositioning #pharmacovigilance #SideEffect #TranslationalSignal
onlinelibrary.wiley.com/doi/10.1111/...
When Side Effects Become Therapies: A Mechanistic Taxonomy of Adverse Drug Reactions as Translational Signals for Drug Repositioning
Background The systematic conversion of adverse drug reactions (ADRs) into new therapeutic indications represents one of the oldest and most productive sources of repositioned drugs; however, it has...
onlinelibrary.wiley.com
July 23, 2026 at 10:21 AM
ernestob.bsky.social
Trimetazidina→↓riesgo nefropatía 2ª contraste en enf renal crónica ─Metanálisis [J Pharm Ther CV] http://ow.ly/QkLW302xYLm #DrugRepositioning
Trimetazidine Decreases Risk of Contrast-Induced Nephropathy in Patients With Chronic Kidney Disease: A Meta-Analysis of Randomized Controlled Trials - PubMed
The addition of TMZ to NS ± NAC significantly decreased the incidence of CIN in patients undergoing coronary angiography. In conclusion, TMZ could be considered as a potential tool for prevention of CIN in patients with renal dysfunction.
ow.ly
November 18, 2024 at 1:19 PM
fcp-sfpt.bsky.social
Now available:
Probucol Exerts Anticancer Effects on SW480 Human Colorectal Cancer Cells via Modulation of Apoptosis- and Angiogenesis-Related Proteins
#clinical #pharmacology #cancer #colorectal #apoptosis #angiogenesis #probucol #SW480 #DrugRepositioning
onlinelibrary.wiley.com/doi/10.1111/...
Probucol Exerts Anticancer Effects on SW480 Human Colorectal Cancer Cells via Modulation of Apoptosis‐ and Angiogenesis‐Related Proteins
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, highlighting the need for novel therapeutic agents with multitarget anticancer activity. Probucol is a pheno...
onlinelibrary.wiley.com
June 29, 2026 at 8:53 AM
fcp-sfpt.bsky.social
Now available:
Repurposing Cimetidine as a Therapeutic Candidate for Irritable Bowel Syndrome in a Rat Model
#clinical #pharmacology #DrugRepositioning #cimetidine #orexin #visceral #GutBarrrier #IrritableBowel #IBS #NHE #preclinical #SFPT @sfpt-fr.org onlinelibrary.wiley.com/doi/10.1111/...
Repurposing Cimetidine as a Therapeutic Candidate for Irritable Bowel Syndrome in a Rat Model
Background Visceral hypersensitivity and impaired intestinal barrier function are hallmark features of irritable bowel syndrome (IBS), linked to activation of corticotropin-releasing factor (CRF), T...
onlinelibrary.wiley.com
May 5, 2026 at 8:52 AM
fcp-sfpt.bsky.social
📣 Drug Repositioning article collection:
Submission end date extended to October 2027!
#fundamental #clinical #pharmacology #preclinical #drug #research #DrugRepositioning #CallForPaper #SFPT @wileyhealth.bsky.social

onlinelibrary.wiley.com/page/journal...
Fundamental & Clinical Pharmacology Call for Papers Drug repositioning
Topics for this call for papers include but are not restricted to:
onlinelibrary.wiley.com
April 27, 2026 at 10:31 AM
fcp-sfpt.bsky.social
FCP- Call for papers!
Drug repositioning article collection!
#SFPT #pharmacology #drug #drugrepositioning #callforpapers

onlinelibrary.wiley.com/page/journal...
Fundamental & Clinical Pharmacology Call for Papers Drug repositioning
onlinelibrary.wiley.com
March 3, 2025 at 1:31 PM
idepiheather.bsky.social
By uniting our efforts, we can drive meaningful progress and improve lives!

#SPAGN #Sarcoma #patients #caregivers #clinicians #treatmentexperiences #CUREID #drugrepurposing #drugrepositioning #rarecancer #rarediseases #Collaboration #HealthcareCommunity #Sarcoma
April 12, 2025 at 3:45 PM
winhide.bsky.social
Dr. Katjusa Koler congrats for passing viva!! Proud of you and the high impact #systemsbiology #drugrepositioning and drug alias tools you built. You join an amazing cast of Hidelab alums @sheffielduni @neuroshef @sheffieldcompsci #neuroscience

tinyurl.com/y7r9heca
December 10, 2024 at 7:43 PM