#ESM1
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sudouest-24.bsky.social
Reprise du CA Périgueux : « Il y a un beau projet donc j’ai voulu en faire partie », Victor Lebas arrive au CAP avec l’expérience de ses 200 matches professionnels
🔗https://l.sudouest.fr/eSM1
August 22, 2026 at 7:06 AM
alexsmithants.bsky.social
🧪🧵

🪰 🐜🪲🐞🦗🐛🦋🪳🦟

After nearly 4 million records, we found extremely high turnover. Most species were exclusive to a single region & each life zone harbors unique assemblages, strongly associated with temperature and precipitation

doi.org/10.1139/gen-...

@gdfcf.bsky.social
@rpuschen.bsky.social
Figure S9. A comparison of betadiversity decay when calculated as Bray Curtis (A, C, E) dissimilarity where points are coloured by the difference in mean annual temperature (A), precipitation (C) or elevation (E) from the 28 Costa Rican locations. Irrespective of index, the sites that are farther apart geographically and by some combination of annual temperature, precipitation or elevation are the most dissimilar. Figure S6. Non-metric multidimensional scaling ordination (NMDS) based on the Bray–Curtis coefficient of community dissimilarity calculated from the 28 localities by 152 891 BIN incidence matrix of Costa Rica insects. Two of the significant vectors here (mean temperature, mean annual precipitation) were derived from the 30 arc-second (1km) resolution of future bioclimatic variables from the ACCESS-ESM1-5 climate model under the SSP5-8.5 emissions scenario for the 2021-2040 period in WorldClim version 2.1. Consensus tree of localities derived from 100 bootstrap replicates, using UPGMA based on Jaccard’s distance.,
August 10, 2026 at 1:57 PM
salvivicidomini.bsky.social
#ESM1 or #Endocan or #endothelial cell specific molecule 1: a key knot (with #HomoCysteine & #NFKB) of the #metabolic #pathway for #human #health.
Public Open Question .. www.researchgate.net/post/Homocys...

Paper TEXT .. www.researchgate.net/post/Homocys... ........
August 30, 2025 at 10:25 AM
oriabe114.bsky.social
www.science.org/doi/10.1126/...
“RA is characterized by pathological fibroblast-like synoviocytes (FLSs)... To address this, Huang et al. focused on the role of small nucleolar RNA, C/D box 3 (SNORD3), which is up-regulated by inflammatory modulators that are important in RA models.”

#arthritis
snoRNA Snord3 promotes rheumatoid arthritis by epigenetic regulation of ESM1 in fibroblast-like synoviocytes in mice
snoRNA Snord3-mediated epigenetic activation of ESM1 is a potential therapeutic target in rheumatoid arthritis.
www.science.org
November 13, 2025 at 2:43 AM
ordofibonacci.bsky.social
Bias correction methods for simulated precipitation in the Brazilian Legal Amazon
Frontiers
www.frontiersin.org/journals/cli...
Frontiers | Bias correction methods for simulated precipitation in the Brazilian Legal Amazon
This study aimed to evaluate precipitation estimates over the Brazilian Legal Amazon (BLA) using high-resolution historical simulations from the MPI-ESM1-2-H...
www.frontiersin.org
August 9, 2025 at 7:53 PM
peakaustria.bsky.social
'extreme heat essentially doubles(!) compared to moderate extreme events.

This modulation of changes in very extreme heat is not only relevant for strong warming scenarios, but emerges already for near term changes' www.nature.com/articles/s41...
Difference between changes in 200-year and 2-year return levels of daily maximum temperature TX for near future climate (2036–2060 vs. 1990–2014) for MPI-ESM1-2-LR. The corresonding results for the other two SMILES can be found in the supplementary material, Figs. S8 and S9. Differences in hatched regions are not significant at the 95% level (see Methods for detail).
January 21, 2025 at 8:11 AM
raindrop-herder.bsky.social
After a full Sunday of fruitless searching I am inclined to agree with you. But my hunt was sparked by this paper agupubs.onlinelibrary.wiley.com/doi/full/10.... (and another two that mention the MPI-ESM1-2-LR past2k expt - for which I *did* find a couple of orphaned centuries)
Sahel Droughts Induced by Large Volcanic Eruptions Over the Last Millennium in PMIP4/Past1000 Simulations
Climate model simulations of the past millennium show Sahel drought in response to large volcanic eruptions up to the following 2 years The mechanisms leading to the Sahel drying are different if...
agupubs.onlinelibrary.wiley.com
January 5, 2026 at 4:25 AM
raindrop-herder.bsky.social
Also I found about two centuries from MPI-ESM1-2-LR (the 'past2k' expt) but no idea what's happened to the rest of it.
January 5, 2026 at 4:00 AM
raindrop-herder.bsky.social
Thanks! I've got past1000 & historical for EC-Earth3-Veg-LR, INM-CM4-8, MIROC-ES2L, MRI-ESM2-0, and ACCESS-ESM1-5.

I have past1000 for EC-Earth3-LR but couldn't find the historical (and also the ACCESS-ESM1-5 hist doesn't match its past1000 -_- ).
January 5, 2026 at 4:00 AM
raindrop-herder.bsky.social
Has anyone here used the PMIP4 past1000 submissions from IPSL-CM6A-LR or MPI-ESM1-2-LR? And more importantly: could point me to where I could find them?! I only recently learned that they exist but can't find them.

At this stage I'm only after tas (past1000 and the associated historical sim)

tyty
January 5, 2026 at 3:22 AM
argosu.bsky.social
www.youtube.com/watch?v=EsM1...
„IMPERATIV” cu Lucan Bălănuță - o dronă rusească s-a prăbuşit pe un bloc din Galaţi
YouTube video by RadioRomania Iasi
www.youtube.com
May 29, 2026 at 7:18 PM
rridrobot.bsky.social
RRID:AB_2832995 from @proteintech.bsky.social was used by authors in their iScience paper. RRIDs improve reproducibility in scientific research. #STMpublishing #RRID #reproducibility
ESM1 drives cisplatin resistance and ferroptosis resistance via ERBB2/FAK/SRC/HSPB1/NF-κB signaling in ovarian cancer
Read the full paper: ESM1 drives cisplatin resistance and ferroptosis resistance via ERBB2/FAK/SRC/HSPB1/NF-κB signaling in ovarian cancer
doi.org
May 28, 2026 at 7:20 AM
rridrobot.bsky.social
RRID:AB_2285104 from @proteintech.bsky.social was used by authors in their Cell Reports paper. Thanks for making your methods matter! #STMpublishing #reproducibility #BetterScience
ESM1 SUMOylation mediates bevacizumab resistance in ovarian cancer through ITGB1-FAK-driven angiogenesis
Read the full paper: ESM1 SUMOylation mediates bevacizumab resistance in ovarian cancer through ITGB1-FAK-driven angiogenesis
doi.org
February 7, 2026 at 8:00 AM
mariefrancemag.bsky.social
Quand l'été rime avec hurlements : apaiser l'angoisse de son chien. 👉 https://l.mariefrance.fr/ESM1
Votre chien hurle dès que vous partez : 4 actions clés et l’erreur qui aggrave son angoisse à coup sûr
June 18, 2026 at 9:06 AM
lemainelibre.bsky.social
La 26e édition des Foulées des Portes du Maine ➡️ https://l.ouest-france.fr/esM1
April 11, 2026 at 8:06 AM
dlr-de.bsky.social
#Artemis I: Beim heutigen, letzten Flyby-Manöver von @NASA_Orion wird sich die Raumkapsel erneut der #Mondoberfläche stark annähern - auf bis zu 127 Km. 🌖 Anschließend tritt @NASAArtemis mit Hilfe des europäischen Servicemoduls #ESM1 seinen Weg nach Hause an, zurück zur Erde. 🌎
January 23, 2025 at 7:24 PM
bob-parker.bsky.social
"Ramses II is Dead, My Love" by The Fugs (1968)

www.youtube.com/watch?v=eSm1...
The Fugs - Ramses ll Is Dead, My Love
YouTube video by Woodward
www.youtube.com
March 11, 2026 at 12:36 AM
haoyin.bsky.social
Human Pancreatic #EndothelialCell scRNAseq

Islet EC▶️PASK ACE ESM1 PLVAP UNC5B THBS1
Acinar EC▶️ AQP1 GPIHBP1 CD74 KLF2/4

Communications with RGS5+ mural cells, LUM+ fibroblasts

#T2D➡️
⏫EC THBS1➡️Fibroblast LRP1/mural cell TNFRSF21

@naturecomms.bsky.social 2025
www.nature.com/articles/s41...
February 27, 2025 at 12:51 PM
haoyin.bsky.social
Fine-grained mapping of #EndothelialCell Zonation at single-cell resolution in developing mouse Kidney😍
#SciArt

👉Nephrogenic zone ESM1
👉Sub-nephrogenic zone Ccdc3
👉Glomeruli Sgk1
AVR DVR...

ESM1-CreERT2 lineage tracing😎

@ondinecleaver.bsky.social bioRxiv 2025
www.biorxiv.org/content/10.1...
February 10, 2025 at 8:12 PM
haoyin.bsky.social
#LymphangiogenesisOnAChip
PDMS #Microfluidics
HDLEC

Pro-sprouting effects
#InterstitialFlow 1 µm/s✅
S1P~Endocan/ESM1 > VEGFA~FGF2 > VEGFC🥸

Does IF modify the potential lymphangiogenic effects of VEGFC?😁

Adv Biol 2024
onlinelibrary.wiley.com/doi/10.1002/...
April 20, 2024 at 6:36 AM
polarocean.bsky.social
The high emissions lead to a change in the buffer capacity that affects trends.

In addition, loss of natural carbon from the ocean is directly related to ocean heat uptake via a 2nd-order polynomial.

Thus, heat uptake can be used to approximate the loss of natural carbon with climate change.
Figure 6The relationship between natural carbon loss and ocean heat uptake and its link to the Atlantic Meridional Overturning Circulation (AMOC). (a) Annual and (b) decadal average air–sea CO2 flux solely caused by ocean heat uptake (for details see Methods) vs. the annual average ocean heat uptake in five different ESMs (ACCESS-ESM1-5 in blue, CanESM5 in orange, MRI-ESM2-0 in green, NorESM2-LM in purple, and UKESM1-0-LL in brown). A second-degree polynomic function (colored lines) was fitted over the decadal average values of each ESM. (c) The CO2 flux per ocean heat uptake, calculated for each model from the fitted second-degree polynomic function at an ocean heat uptake of 35 ZJ yr−1 against the AMOC at 26.5° N calculated in each ESM from 2004 to 2018 (historical plus SSP5-8.5 simulations). The vertical dashed black line and the gray shading indicate the average observed AMOC at the RAPID array from 2004 to 2018 (McCarthy et al., 2020).
December 4, 2024 at 11:58 AM
euronewsespanol.bsky.social
Hallan un agujero negro con más energía que la Estrella de la Muerte
➡️ https://l.euronews.com/eSm1
February 6, 2026 at 1:51 AM
d3v1ls7h3r4p157.bsky.social
Mournings #doomisphere 🤗

a new #CrisisReport dropped! This is why we DOOM ladies n gents! 🥰
#DoomersFinest

"Although this graph is meant to be #reassuring in that it shows global #warming can be #constrained to around +3°C, it is actually kind of #terrifying when you understand several things
1/3
From: Exploring climate stabilisation at different global warming levels in ACCESS-ESM-1.5 — October 30th, 2024. Global mean surface temperature (GMST) anomalies, relative to the 1850–1900 baseline, in the ACCESS-ESM1–5 historical and SSP5–8.5 simulations (black) and the net-zero greenhouse gas emission simulations (grading from yellow to red for later emission cessation). The net-zero emission simulations begin in 2030, 2035, 2040, 2045 (GREEN arrow), 2050, 2055, and 2060. Link: https://esd.copernicus.org/articles/15/1353/2024/
February 26, 2025 at 10:48 AM
gemhough.bsky.social
Potential effects of possible climate change on sea surface temperatures: the case of the southern Black Sea coast
Potential effects of possible climate change on sea surface temperatures: the case of the southern Black Sea coast
Understanding climate change’s possible effects on sea surface temperatures (SSTs) is vital for marine ecosystems. For the first time, the potential effects of climate change on SSTs were investigated using the SST data from five meteorological observation stations located along the Black Sea coast of Türkiye, covering the period 1963–2014. The SSP2-4.5 and SSP5-8.5 scenario outputs of the general circulation models, namely CNRM-ESM2-1, MPI-ESM1-2-HR, MRI-ESM2-0, and NORESM2-MM, selected from the Coupled Model Intercomparison Project Phase 6 archive were downscaled to station scale by conventional regression analysis and artificial neural networks as statistical downscaling method in the study. SST values for the future periods (2023–2052 and 2053–2082) were obtained using the ensemble model approach for each station. Additionally, quantile delta mapping was used for bias correction. Three performance metrics were used to evaluate the downscaling performance of the methods. The model with the best performance was selected, and the future SST results were obtained and compared with the historical observation data. It was projected that monthly SSTs may increase by 1.66 °C–4.25 °C under the SSP2-4.5 scenario and 1.71 °C–5.75 °C under the SSP5-8.5 scenario. This increases may cause the deterioration of the marine ecosystem and local economic downturn in the Southwestern Black Sea.
dlvr.it
May 29, 2025 at 4:39 PM
pfcook.bsky.social
Somehow despite this handsome dude, I have noticed that sea lions have a bad name on the internet. We otariid enthusiasts must do our part to address that. My daily effort - sea lion besting humans at beat keeping: youtu.be/oen67G5w5S0
Battle of the Beats: Sensorimotor Synchronization to Rhythm in an Experienced Sea Lion - ESM1
YouTube video by Carson Hood
youtu.be
May 2, 2025 at 12:30 AM