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Patients with FS/PNES show significantly lower DTI-ALPS index compared to HC, suggesting potential glymphatic system dysfunction.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ILAE #functionalneurologicaldisorders #functionalseizures #glymphaticsystem #PNES
August 8, 2025 at 4:58 PM
epilepsia-open.bsky.social
New in Epilepsia Open – November 9, 2025
mailchi.mp/ilae/epileps...

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#epilepsy #epilepsiaopen #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
November 10, 2025 at 3:51 PM
epilepsia-open.bsky.social
In the cavernous sinus, eEEG detected IEDs with higher amplitude than scalp EEG, indicating its diagnostic potential.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #EP01 #focalonsetepilepsy #localizedepileptogenicity
December 12, 2025 at 4:56 PM
epilepsia-open.bsky.social
Key point: Anxiety and depression are associated with different subjective memory complaints in people with epilepsy.
doi.org/10.1002/epi4...

#epilepsy #ilae #epilepsiaopen #anxiety #depression #mood #subjectivememorycomplaints
March 28, 2025 at 6:13 PM
epilepsia-open.bsky.social
SARS-CoV-2 infection causes long-term neurological and psychiatric symptoms in PwE.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #healthcare #intervention #postacutesequelae #COVID19 #SARSCoV2
August 26, 2025 at 8:22 PM
epilepsia-open.bsky.social
This study assessed neurologists' practices and barriers to epilepsy genetic testing/counseling compared to guidelines published in 2022.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #adultneurologists #bestpractices #genomics #unexplainedepilepsy
September 12, 2025 at 8:53 PM
epilepsia-open.bsky.social
Key point: The reciprocal communication between the gut and the brain may be altered in pediatric epilepsies.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ILAE #animalmodels #drugresistance #gutbrainaxis #metabolomics #metagenomics #microbiota
April 24, 2025 at 6:25 PM
epilepsia-open.bsky.social
Key point: Thirty-five pediatric patients treated with neuromodulation showed 66% response rate at most recent follow-up.
onlinelibrary.wiley.com/doi/10.1002/...

#epilepsy #ilae #epilepsiaopen #neurostimulation #neuromodulation #DBS #RNS
April 8, 2025 at 9:19 PM
epilepsia-open.bsky.social
This review provides a practical approach to assessing and selecting PROMs, and discusses how they may be incorporated into clinic workflows.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #mooddisorders #patientreportedoutcome #qualityoflife #seizure
November 11, 2025 at 3:46 PM
epilepsia-open.bsky.social
March 31
Epilepsia Open - Recently published articles (March 30, 2025)
mailchi.mp/ilae/epileps...

#epilepsy #Ilae #epilepsiaopen #newarticles
March 31, 2025 at 1:38 PM
epilepsia-open.bsky.social
New in Epilepsia Open – December 7, 2025
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#epilepsy #epilepsiaopen #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
December 8, 2025 at 8:37 PM
epilepsiajournal.bsky.social
New in Epilepsia Open – November 1, 2025
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#epilepsy #epilepsiaopen #ILAE #EpilepsyResearch #NewInEpilepsy #JustPublished #LatestResearch
November 3, 2025 at 7:31 PM
epilepsia-open.bsky.social
Epilepsy is associated with significantly increased long-term risk of cardiovascular disease.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #cardiovasculardiseases #riskfactors #SouthKorea
November 19, 2025 at 7:04 PM
epilepsia-open.bsky.social
Internal laboratory data relevant to VUS is frequently omitted from clinical reports.
doi.org/10.1002/epi4...

#epilepsy #ilae #epilepsiaopen #Documentation #genetics #laboratorycorrespondence #pediatrics
September 10, 2025 at 9:30 PM
epilepsia-open.bsky.social
URE patients had a median of six failed treatment strategies, including surgery or neurostimulation.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #antiseizuremedication #drugresistantepilepsy #neurostimulation #resectivebrainsurgery #ultrarefractoryepilepsy
December 15, 2025 at 7:12 PM
epilepsia-open.bsky.social
Progressive clonic slowing is associated with marked oxygen desaturation during bilateral tonic–clonic seizures.
doi.org/10.1002/epi4...

#epilepsy #ilae #epilepsiaopen #SUDEP #Progressiveclonicslowing #PostictalImmobility #Tonicclonicseizure #Respiratorydysfunction
October 22, 2025 at 7:22 PM
epilepsia-open.bsky.social
The preponderance of evidence indicates that the KD is effective in targeting IESS.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #acidosis #infantileepilepticspasms #ketogenicdiet #microbiome #tryptophan
November 4, 2025 at 5:50 PM
epilepsia-open.bsky.social
Key point: ChatGPT 3.5 and Perplexity accurately answered most Dravet syndrome questions.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ILAE #Artificialintelligence #ChatGPT #Dravetsyndrome #Largelanguagemodel #Perplexity #AI
April 10, 2025 at 9:28 PM
epilepsia-open.bsky.social
Global adolescent epilepsy burden increased 1990–2021, with marked regional and SDI disparities.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #adolescenthealth #globalburdenofdisease #healthpolicy #publichealth
November 7, 2025 at 3:33 PM
epilepsia-open.bsky.social
Clobazam, stiripentol, and fenfluramine reduce seizures effectively; valproic acid has no significant effect.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ILAE #antiseizuremedication #DEE #Dravetsyndrome #Drosophilamelanogaster
August 1, 2025 at 3:23 PM
epilepsia-open.bsky.social
Absence seizures (AS) involve widespread brain networks beyond the cortico-thalamo-cortical loop.
doi.org/10.1002/epi4...

#epilepsy #ilae #epilepsiaopen #basalganglia #cerebellum #idiopathicgeneralizedepilepsies #limbicsystem #spikeandwavedischarges
July 10, 2025 at 2:21 PM
epilepsia-open.bsky.social
Key point: IGE showed mood state abnormality compared to HCs regardless of seizure control.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #arterialspinlabeling #cerebralbloodflow #idiopathicgeneralizedepilepsy #mooddysfunction #seizurecontrol
May 7, 2025 at 9:19 PM
epilepsia-open.bsky.social
The ELUCID Study is a prospective, multi-site, longitudinal observational study on late-onset unexplained epilepsy (LoUE).
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #cognition #dementia #elderly #lateonset
December 9, 2025 at 3:44 PM
epilepsia-open.bsky.social
Barriers to SUDEP talks include time limits, fear of distress, and doubts about patient understanding.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #mortality #seizures #SUDEP #SUDEPcommunication
September 19, 2025 at 3:40 PM
epilepsia-open.bsky.social
One-third of people with epilepsy continue to have seizures despite new anti-seizure medications.
doi.org/10.1002/epi4...

#epilepsy #epilepsiaopen #ILAE #Delphiconsensusstudy #drugresistantepilepsy #DRE #epilepsymanagement #uncontrolledepilepsy
August 12, 2025 at 2:29 PM