#Fiberseq
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epicypher.bsky.social
🧬 EpiCypher is presenting at the 2026 EMGS Virtual Meeting!

👨‍🔬 Hear Keith Maier, PhD, present:

🔬 Fiber-seq: Linking DNA Methylation to Chromatin Accessibility with Single-Molecule Long-Read Multiomics

🔗 https://ow.ly/ruzU50ZWk59

#EMGS2026 #FiberSeq
October 9, 2026 at 4:31 PM
epicypher.bsky.social
Did you miss us at AACR Drug Discovery and Development (AACR D3) last week? Download our posters to see the exciting science presented by Morgan Oatley and Keith Maier!

1️⃣🔗https://ow.ly/rbPf50ZstVf
2️⃣🔗https://ow.ly/XiBr50ZstVc

#AACRdrugdev26 #Fiberseq #FFPE #Epigenetics
July 27, 2026 at 2:05 PM
epicypher.bsky.social
What does short-read epigenomics miss?

A study using Fiber-seq on human brain tissue found ~20,000 accessible chromatin regions missed by short-read methods. Read our new blog to learn more⤵️
https://ow.ly/uAxw50Z1kAi

#FiberSeq #Epigenomics
May 20, 2026 at 2:02 PM
epicypher.bsky.social
How can you profile chromatin accessibility, DNA methylation, and protein footprints in a single assay?

🔗 Read more: https://www.epicypher.com/resources/blog/fiber-seq-101/

#Epigenomics #Chromatin #ATACseq #Multiomics #Fiberseq #EpiCypher
Fiber-seq 101: A Multiomic Assay That Goes Beyond ATAC-seq - EpiCypher
Fiber-seq is a powerful new long-read sequencing assay to simultaneously study genetic and epigenetic features. Read more!
www.epicypher.com
January 22, 2026 at 3:00 PM
epicypher.bsky.social
Coming to #PAG2026? Drop by booth 329 to chat with EpiCypher about Fiber-seq – a powerful new way to see chromatin architecture at the single-molecule level.
Ask us how it works (and get some swag).
#Fiberseq #Chromatin
January 2, 2026 at 6:00 PM
epicypher.bsky.social
That’s a wrap on #SfN2025! 🧠
Grateful for all the great chats on Fiber-seq, CUTANA™ Cloud, and FFPE-based chromatin profiling in the brain.
#Epigenetics #Neuroscience #FiberSeq
November 20, 2025 at 3:02 PM
epicypher.bsky.social
Huge thanks to everyone who visited us on Day 1 of #ASHG2025! 👏 If you haven’t yet, swing by Booth 530 today to explore Fiber-seq – a multiomic long-read tech to co-profile chromatin accessibility, DNA methylation, and protein footprints.
#Epigenetics #FiberSeq #ASHG
October 16, 2025 at 2:04 PM
epicypher.bsky.social
Heading to #ASHG2025? Don’t miss Emily Madden’s talk:

🧬 “Unraveling Regulatory Architecture in Complex Genomic Regions Using Fiber-seq”
🗓️ Fri, Oct 17 | 10:15am ET
📍 CoLab Theater 1 (PacBio)

#Epigenetics #Fiberseq #Chromatin
October 14, 2025 at 5:03 PM
epicypher.bsky.social
How can you profile chromatin accessibility, DNA methylation, & protein footprints in ONE assay?

💡 In our new Fiber-seq 101 blog, we break down how this platform is transforming epigenomics.

🔗 Read more: www.epicypher.com/resources/bl...

#Epigenomics #ATACseq #Multiomics #Fiberseq
October 14, 2025 at 3:01 PM
epicypher.bsky.social
Today at #AGBT: 4–5 PM PT — Keith Maier presents Poster #507
Standardizing Fiber-seq for direct multi-omic chromatin profiling at single-molecule resolution 🧬

📥 Grab the poster: explore.epicypher.com/posters/agbt...

#Epigenetics #Fiberseq #Multiomics
September 9, 2025 at 2:06 PM
epicypher.bsky.social
Just announced: CUTANA™ Fiber-seq — a game-changing platform for multiomic profiling of chromatin accessibility, DNA methylation, protein footprints, and genetic variants in a single assay.

🔗 www.epicypher.com/resources/bl...

#Epigenetics #Fiberseq #Chromatin
September 5, 2025 at 1:17 PM
epicypher.bsky.social
Are you attending Epigenetic Variation: Mechanisms and Impact across Systems in Barcelona? 🧬

Catch Dr. James Anderson’s talk on Fiber-seq 🧬, a multi-omic LRS method revealing chromatin, TFs, DNAme and haplotypes in one assay.

📍 Aug 14 | 🕘 9am CEST

#Epigenetics #FiberSeq #LRS
August 7, 2025 at 5:04 PM
estuvalencia.bsky.social
Check out my first blog for the good people at @epicypher.bsky.social, which describes the huge potential of Fiber-seq! Enjoy!

#Epigenetics #Fiberseq #Blog
epicypher.bsky.social EpiCypher @epicypher.bsky.social · May 20
What does short-read epigenomics miss?

A study using Fiber-seq on human brain tissue found ~20,000 accessible chromatin regions missed by short-read methods. Read our new blog to learn more⤵️
https://ow.ly/uAxw50Z1kAi

#FiberSeq #Epigenomics
May 20, 2026 at 2:24 PM
edgenome.bsky.social
We’re excited to see what new insights emerge from these advances! 🚀

Want to know more about using Jasmine and Fiber-seq in your projects? Let’s chat!

📧 edgenomics-admin@ed.ac.uk

#FiberSeq #Genomics #Epigenetics #LongReadSequencing #Bioinformatics

🧵6/6
December 5, 2024 at 4:33 PM
edgenome.bsky.social
With @pacbio.bsky.social’s Jasmine software, we can now offer 6-base calling (ATCG+5mC+6mA) on the #Revio platform—at no extra cost in sequencing consumables. 🔬🙌

Learn more about Jasmine: github.com/PacificBiosc...

#FiberSeq #Genomics #Epigenetics #LongReadSequencing #Bioinformatics

🧵5/6
GitHub - PacificBiosciences/jasmine: Predict 5mC in PacBio HiFi reads
Predict 5mC in PacBio HiFi reads. Contribute to PacificBiosciences/jasmine development by creating an account on GitHub.
github.com
December 5, 2024 at 4:33 PM
edgenome.bsky.social
📚 Case Study:
A new paper uncovers how repeat-region instability disrupts nearby regulatory elements, revealing a disease mechanism and potential therapeutic target in #MyotonicDystrophy

Read more: biorxiv.org/content/10.1...

#FiberSeq #GeneRegulation #Genomics #Epigenetics

🧵4/6
biorxiv.org
December 5, 2024 at 4:33 PM
edgenome.bsky.social
@pacbio.bsky.social or @nanoporetech.com sequencing captures this signal, and with new software and resources to interpret the Fiber-seq data our view into the mechanisms of gene regulation has never been clearer.

Learn about the tools:
github.com/fiberseq/FIRE
fiberseq.github.io/index.html

🧵3/6
GitHub - fiberseq/FIRE: A Snakemake workflow for calling Fiber-seq Inferred Regulatory Elements (FIREs) on single molecules.
A Snakemake workflow for calling Fiber-seq Inferred Regulatory Elements (FIREs) on single molecules. - fiberseq/FIRE
github.com
December 5, 2024 at 4:33 PM
edgenome.bsky.social
In the Fiber-seq protocol, chromatin accessibility is revealed by treating the DNA with non-specific N6-adenine methytransferase to create an m6A fingerprint on the DNA itself.

Learn more: stergachislab.org/research

#FiberSeq #GeneRegulation #Epigenetics

🧵2/6
research — stergachislab
stergachislab.org
December 5, 2024 at 4:33 PM
edgenome.bsky.social
"Fiber-seq continues to transform our understanding of gene regulation" — as @pacbio.bsky.social recently highlighted. Let’s dive into how this innovative tech works and why it’s a game-changer. 🔬✨🧬🖥️

pacb.com/blog/powered...

#FiberSeq #PacBio #GeneRegulation #Epigenetics

🧵1/6
Powered by PacBio: Selected publications from July 2024 - PacBio
Explore July 2024's selected scientific papers powered by PacBio HiFi sequencing - Targeted sequencing, metagenomics, immunology, and more.
pacb.com
December 5, 2024 at 4:33 PM
mollyschumer.bsky.social
What are people using for calling m6A from pacbio revio data? This is for analysis of fiberseq library. Any suggestions appreciated, we are newbies with m6A analysis!
September 29, 2025 at 2:31 AM