1/n New paper alert 🚨 We're thrilled to share our just published paper in #CancerCell
Do you ever wonder how the #TME in #HGSC changes during chemotherapy? Check it here: www.sciencedirect.com/science/arti... and let’s dive into the highlights together #spatialbiology #ovariancancer #cancerresarch
Do you ever wonder how the #TME in #HGSC changes during chemotherapy? Check it here: www.sciencedirect.com/science/arti... and let’s dive into the highlights together #spatialbiology #ovariancancer #cancerresarch
Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer
Anti-tumor immunity is crucial for high-grade serous ovarian cancer (HGSC) prognosis, yet its adaptation upon standard chemotherapy remains poorly und…
www.sciencedirect.com
December 10, 2024 at 11:48 AM
1/n New paper alert 🚨 We're thrilled to share our just published paper in #CancerCell
Do you ever wonder how the #TME in #HGSC changes during chemotherapy? Check it here: www.sciencedirect.com/science/arti... and let’s dive into the highlights together #spatialbiology #ovariancancer #cancerresarch
Do you ever wonder how the #TME in #HGSC changes during chemotherapy? Check it here: www.sciencedirect.com/science/arti... and let’s dive into the highlights together #spatialbiology #ovariancancer #cancerresarch
Puyo Puyo DA! ~ Arle Arcade
YouTube video by Nozwhompolton
www.youtube.com
December 31, 2025 at 7:53 AM
A @humblegents.bsky.social classic on me Ed, with one of the best waterproof jackets I own,for a day on the beach 🏝️ 🤦♂️🤣🤣 #gill #navigator #hgsc
December 2, 2024 at 11:42 AM
A @humblegents.bsky.social classic on me Ed, with one of the best waterproof jackets I own,for a day on the beach 🏝️ 🤦♂️🤣🤣 #gill #navigator #hgsc
Glad to have presented our work on the longitudinal dynamics of transcriptome and chromatin accessibility in HGSC at the #EACR2025 in Lisbon 🇵🇹
June 17, 2025 at 9:03 PM
Glad to have presented our work on the longitudinal dynamics of transcriptome and chromatin accessibility in HGSC at the #EACR2025 in Lisbon 🇵🇹
MD/PhD student Mihai Dumbrava from our #LabFunEpi presenting his work about an epigenetic persister cell signature using single using single cell ATAC+RNA profiling of HGSC patient samples at the AACR Ovarian cancer meeting in Denver CO.
September 20, 2025 at 9:45 PM
MD/PhD student Mihai Dumbrava from our #LabFunEpi presenting his work about an epigenetic persister cell signature using single using single cell ATAC+RNA profiling of HGSC patient samples at the AACR Ovarian cancer meeting in Denver CO.
Dr. Davidson submitted a proposal to the Boettcher Foundation! Single-cell sequencing revealed that High-grade serous carcinoma subtypes are driven by microenvironment changes. She seeks to redefine HGSC subtypes & assess functional impacts on biomarkers w/ chemotherapy.🤞#HGSC #GynOnc #CUAnschutz
March 19, 2025 at 3:09 PM
Dr. Davidson submitted a proposal to the Boettcher Foundation! Single-cell sequencing revealed that High-grade serous carcinoma subtypes are driven by microenvironment changes. She seeks to redefine HGSC subtypes & assess functional impacts on biomarkers w/ chemotherapy.🤞#HGSC #GynOnc #CUAnschutz
@afarkkila.bsky.social, Sara, Ada, and Aleksandra are representing the lab at ESSB in Berlin!
Find them to discuss spatial biology!
🟠 Poster #88: Ada presents a spatial study of the cell cycle in #HGSC
🟠 Poster #155: Aleksandra showcases the use of ML to uncover spatial tumor ecosystems
Find them to discuss spatial biology!
🟠 Poster #88: Ada presents a spatial study of the cell cycle in #HGSC
🟠 Poster #155: Aleksandra showcases the use of ML to uncover spatial tumor ecosystems
December 12, 2024 at 11:58 AM
@afarkkila.bsky.social, Sara, Ada, and Aleksandra are representing the lab at ESSB in Berlin!
Find them to discuss spatial biology!
🟠 Poster #88: Ada presents a spatial study of the cell cycle in #HGSC
🟠 Poster #155: Aleksandra showcases the use of ML to uncover spatial tumor ecosystems
Find them to discuss spatial biology!
🟠 Poster #88: Ada presents a spatial study of the cell cycle in #HGSC
🟠 Poster #155: Aleksandra showcases the use of ML to uncover spatial tumor ecosystems
Congrats to Dr. Bitler and Courtney Bailey, PhD candidate, on receiving a Grubstake Award from the CU Gates Institute! 🎉Their project, “Macrophage Backpacks for Delivering Olaparib to HGSC,” was awarded $300,000 over 2 years. bit.ly/4jXkQgW
@uccc-gorg.bsky.social @courtneybailey.bsky.social
@uccc-gorg.bsky.social @courtneybailey.bsky.social
January 26, 2026 at 10:08 PM
Congrats to Dr. Bitler and Courtney Bailey, PhD candidate, on receiving a Grubstake Award from the CU Gates Institute! 🎉Their project, “Macrophage Backpacks for Delivering Olaparib to HGSC,” was awarded $300,000 over 2 years. bit.ly/4jXkQgW
@uccc-gorg.bsky.social @courtneybailey.bsky.social
@uccc-gorg.bsky.social @courtneybailey.bsky.social
Spatial proteomics & transcriptomics chart #ovariancancer evolution from fallopian tube precursors. Deep Visual Proteomics reveals early SUMOylation, TRIP13 epithelial driver, BGN therapeutic target & epithelial-stromal cooperation in progression.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Integration of cell-type resolved spatial proteomics and transcriptomics reveals novel mechanisms in early ovarian cancer
High-grade serous carcinoma (HGSC) is the most common ovarian cancer subtype, typically diagnosed at late stages with poor prognosis. Understanding early molecular events driving HGSC progression is c...
www.medrxiv.org
August 29, 2025 at 8:48 AM
Spatial proteomics & transcriptomics chart #ovariancancer evolution from fallopian tube precursors. Deep Visual Proteomics reveals early SUMOylation, TRIP13 epithelial driver, BGN therapeutic target & epithelial-stromal cooperation in progression.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
We had a wonderful bioinformatics Hackathon last week
@HGSC with ~75 participants around the world. We had exceptional teams & after a short presentation nominated 3 winning teams: A mosaic mutation simulator, graph genomes in metagenomics & detection of de novo variants.
github.com/collaborativ...
@HGSC with ~75 participants around the world. We had exceptional teams & after a short presentation nominated 3 winning teams: A mosaic mutation simulator, graph genomes in metagenomics & detection of de novo variants.
github.com/collaborativ...
September 12, 2023 at 12:24 AM
We had a wonderful bioinformatics Hackathon last week
@HGSC with ~75 participants around the world. We had exceptional teams & after a short presentation nominated 3 winning teams: A mosaic mutation simulator, graph genomes in metagenomics & detection of de novo variants.
github.com/collaborativ...
@HGSC with ~75 participants around the world. We had exceptional teams & after a short presentation nominated 3 winning teams: A mosaic mutation simulator, graph genomes in metagenomics & detection of de novo variants.
github.com/collaborativ...
Codes:
vbyq-gwdu
9vu6-b4sp
nf5k-wqc2
m5rt-htsc
b6m2-v2hw
camb-khyd
swnf-ukwv
mkhg-cb85
bvy4-vw3g
27at-wmc2
a5fy-hgsc
r8a3-vbhw
vbyq-gwdu
9vu6-b4sp
nf5k-wqc2
m5rt-htsc
b6m2-v2hw
camb-khyd
swnf-ukwv
mkhg-cb85
bvy4-vw3g
27at-wmc2
a5fy-hgsc
r8a3-vbhw
November 4, 2025 at 6:06 AM
Codes:
vbyq-gwdu
9vu6-b4sp
nf5k-wqc2
m5rt-htsc
b6m2-v2hw
camb-khyd
swnf-ukwv
mkhg-cb85
bvy4-vw3g
27at-wmc2
a5fy-hgsc
r8a3-vbhw
vbyq-gwdu
9vu6-b4sp
nf5k-wqc2
m5rt-htsc
b6m2-v2hw
camb-khyd
swnf-ukwv
mkhg-cb85
bvy4-vw3g
27at-wmc2
a5fy-hgsc
r8a3-vbhw
🎉Dr. Lindsay Brubaker is tackling therapy resistance in #HGSC with cutting-edge research on antibody-drug conjugates (ADCs). Backed by a competitive DOD grant, her study explores epigenetic drivers to expand and improve treatment options. View Article bit.ly/4fxHr1E #OvarianCancer #CUAnschutz
August 11, 2025 at 4:48 PM
🎉Dr. Lindsay Brubaker is tackling therapy resistance in #HGSC with cutting-edge research on antibody-drug conjugates (ADCs). Backed by a competitive DOD grant, her study explores epigenetic drivers to expand and improve treatment options. View Article bit.ly/4fxHr1E #OvarianCancer #CUAnschutz
www.youtube.com/watch?v=hGSC...
GET TF OUT DIDDLER !!!!!! WE NEVER WANTED ANY OF THIS!!!!!!
GET TF OUT DIDDLER !!!!!! WE NEVER WANTED ANY OF THIS!!!!!!
🚨Trump in SEVERE PANIC as his HEALTH COLLAPSES
YouTube video by MeidasTouch
www.youtube.com
December 20, 2025 at 3:50 PM
www.youtube.com/watch?v=hGSC...
GET TF OUT DIDDLER !!!!!! WE NEVER WANTED ANY OF THIS!!!!!!
GET TF OUT DIDDLER !!!!!! WE NEVER WANTED ANY OF THIS!!!!!!
New preprint alert ‼️ @farkkilab.bsky.social We generated a single-cell spatial atlas of 280 metastatic #ovariancancer and found tumor MHCII as a key driver of tumor ecosystems and clinical outcomes. www.biorxiv.org/content/10.1...
Single-cell spatial atlas of high-grade serous ovarian cancer unveils MHC class II as a key driver of spatial tumor ecosystems and clinical outcomes
The tumor microenvironment (TME) is a complex network of interactions between malignant and host cells, yet its orchestration in advanced high-grade serous ovarian carcinoma (HGSC) remains poorly unde...
www.biorxiv.org
December 4, 2024 at 5:33 AM
New preprint alert ‼️ @farkkilab.bsky.social We generated a single-cell spatial atlas of 280 metastatic #ovariancancer and found tumor MHCII as a key driver of tumor ecosystems and clinical outcomes. www.biorxiv.org/content/10.1...
🚨Trump in SEVERE PANIC as his HEALTH COLLAPSES🚨
Donald Trump’s health rapidly deteriorating as he becomes terrified at his failing body and basic functions.
www.youtube.com/watch?v=hGSC...
Donald Trump’s health rapidly deteriorating as he becomes terrified at his failing body and basic functions.
www.youtube.com/watch?v=hGSC...
🚨Trump in SEVERE PANIC as his HEALTH COLLAPSES
YouTube video by MeidasTouch
www.youtube.com
December 20, 2025 at 1:51 PM
🚨Trump in SEVERE PANIC as his HEALTH COLLAPSES🚨
Donald Trump’s health rapidly deteriorating as he becomes terrified at his failing body and basic functions.
www.youtube.com/watch?v=hGSC...
Donald Trump’s health rapidly deteriorating as he becomes terrified at his failing body and basic functions.
www.youtube.com/watch?v=hGSC...
Momie Yamamoto and Ritz Iwanaga from Dr. Bitler's lab at CU Anschutz recently submitted a paper showing that Chromobox2 (CBX2) plays a role in driving HGSC progression. This suggests a potential new treatment option for HGSC patients. Wish them luck publishing their paper #HGSC #GynOnc #CUAnschutz
March 26, 2025 at 2:58 PM
Momie Yamamoto and Ritz Iwanaga from Dr. Bitler's lab at CU Anschutz recently submitted a paper showing that Chromobox2 (CBX2) plays a role in driving HGSC progression. This suggests a potential new treatment option for HGSC patients. Wish them luck publishing their paper #HGSC #GynOnc #CUAnschutz
5/n On the other hand, chemo reshapes the spatial landscape of #HGSC, transforming an spatially confined immunophenotype into a more infiltrated one. CD8+ T cells migrate from their “private” neighbourhoods toward cancer cell-hubs and #Myelonets.
December 10, 2024 at 11:48 AM
5/n On the other hand, chemo reshapes the spatial landscape of #HGSC, transforming an spatially confined immunophenotype into a more infiltrated one. CD8+ T cells migrate from their “private” neighbourhoods toward cancer cell-hubs and #Myelonets.
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models https://www.biorxiv.org/content/10.1101/2024.11.21.624591v1
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models https://www.biorxiv.org/content/10.1101/2024.11.21.624591v1
Tubo-ovarian high-grade serous carcinoma (HGSC) is the most lethal gynecological malignancy and freq
www.biorxiv.org
November 23, 2024 at 12:50 AM
Coordinated protein modules define DNA damage responses to carboplatin at single cell resolution in human ovarian carcinoma models https://www.biorxiv.org/content/10.1101/2024.11.21.624591v1
High-grade serous carcinoma is a tough ovarian cancer to treat and often recurs after chemotherapy. Dr. Marjon recently resubmitted a paper showing that targeting certain tumor immune cells could help make treatments like chemotherapy more effective. Wishing her luck🤞 #HGSC #CUAnschutz #GynOnc
April 15, 2025 at 5:55 PM
High-grade serous carcinoma is a tough ovarian cancer to treat and often recurs after chemotherapy. Dr. Marjon recently resubmitted a paper showing that targeting certain tumor immune cells could help make treatments like chemotherapy more effective. Wishing her luck🤞 #HGSC #CUAnschutz #GynOnc
Join us for the Pharmacology Seminar Series as Dr. Elizabeth Woodruff discusses how chronic stress influences #HGSC progression and immune response through adrenergic signaling in the omentum. #OvarianCancer #GynOnc #CUAnschutz
Date 📅: Mon, 10/20/25, 12:00 PM MST
Location📍: RC1 North, Room 6107
Date 📅: Mon, 10/20/25, 12:00 PM MST
Location📍: RC1 North, Room 6107
October 16, 2025 at 4:51 PM
Join us for the Pharmacology Seminar Series as Dr. Elizabeth Woodruff discusses how chronic stress influences #HGSC progression and immune response through adrenergic signaling in the omentum. #OvarianCancer #GynOnc #CUAnschutz
Date 📅: Mon, 10/20/25, 12:00 PM MST
Location📍: RC1 North, Room 6107
Date 📅: Mon, 10/20/25, 12:00 PM MST
Location📍: RC1 North, Room 6107
Homologous recombination deficiency in ovarian high-grade serous carcinoma by self-reported race
#preprint
www.medrxiv.org/content/10.1...
#preprint
www.medrxiv.org/content/10.1...
Homologous recombination deficiency in ovarian high-grade serous carcinoma by self-reported race
Background Approximately half of ovarian high-grade serous carcinomas (HGSC) have homologous recombination deficiency (HRD). However, HRD is not well-characterized in Black individuals.
Objective To ...
www.medrxiv.org
January 31, 2025 at 8:16 PM
Homologous recombination deficiency in ovarian high-grade serous carcinoma by self-reported race
#preprint
www.medrxiv.org/content/10.1...
#preprint
www.medrxiv.org/content/10.1...
infelizmente a prima de hgsc return of gangster vamos abafando entao
LIMITES! Em mais um ato de censura, o novo drama coreano “Jeongnyeon: The Star is Born” teve os elementos GL RETIRADOS por motivos de “materiais sensíveis”.
A série estrelada por Kim TaeRi é uma adaptação do webtoon, onde a protagonista sonha ser uma cantora e tem interesse romântico por mulheres.
A série estrelada por Kim TaeRi é uma adaptação do webtoon, onde a protagonista sonha ser uma cantora e tem interesse romântico por mulheres.
September 16, 2024 at 1:56 AM
infelizmente a prima de hgsc return of gangster vamos abafando entao