#ImmunoSep
Annelies Zinkernagel at #ESCMIDGlobal2026 TIGRIS, ANDROMEDA-2, ImmunoSep trials show that the era of precision medicine in #Sepsis management has arrived
April 20, 2026 at 8:30 AM
Just 4 weeks to CCR Down Under 2025!

Join us to hear the results of 8 major critical care trials - in person or virtually

➡️ ImmunoSep
➡️ iRehab
➡️ CLIP II
➡️ ACTiVE
➡️ ARISE AFRICA
➡️ RSI
➡️ VITaCCA
➡️ ECMO REHAB

https://criticalcarereviews.com/meetings/ccr-down-under-2025
November 11, 2025 at 10:10 PM
Chief Investigator, Evangelos Giamarellos-Bourboulis shares the findings from the #ImmunoSep trial and what it means for clinicians at #CCRdownunder

Livestream -> www.criticalcarereviews.com

@jama.com
December 9, 2025 at 7:13 AM
📊 Research Summary: The ImmunoSep trial demonstrates the potential for biomarker-guided immunotherapy in a subset of patients with sepsis. #CCRdownunder ja.ma/4pMi8wt
December 8, 2025 at 10:45 PM
Editorial by JAMA Senior Editor Derek Angus: The ImmunoSep RCT demonstrates the feasibility of biomarker-guided treatment, while highlighting ongoing challenges in immune classification and broader clinical application. #CCRdownunder ja.ma/3Kg3qz3
December 8, 2025 at 11:00 PM
ImmunoSep uses a double-dummy design.
What is this? It is a design to maintain blinding when 2 treatments can't be made identical- all participants receive 2 treatments- one which is active and the other which is placebo #ccrdownunder
jama.com JAMA @jama.com · Dec 8
RCT: Among patients with #sepsis, a precision immunotherapy strategy targeting macrophage activation-like syndrome and sepsis-induced immunoparalysis improved organ dysfunction by day 9 compared to placebo.#CCRdownunder ja.ma/3MkSb95
December 8, 2025 at 10:46 PM
💬 Editorial by JAMA Senior Editor Derek Angus, MD, MPH: The ImmunoSep RCT demonstrates the feasibility of biomarker-guided treatment, while highlighting ongoing challenges in immune classification and broader clinical application.

ja.ma/4u0WEzb
March 3, 2026 at 5:15 PM
Precision matters in #sepsis. At #ESCMIDGlobal2026, across ASTONISH and IMMUNOSEP, outcomes varied by subgroup. Primary endpoints were achieved in targeted patients but mortality benefit was not significant. Signals emerge over time. How should we interpret this? #Immunotherapy
April 20, 2026 at 7:39 AM
Precision Immunotherapy to Improve Sepsis Outcomes - The ImmunoSep Randomized Clinical Trial
Evangelos J. Giamarellos-Bourboulis, et al.
JAMA, 2025
jamanetwork.com/journals/jam...
Precision Immunotherapy to Improve Sepsis Outcomes
This randomized trial assesses whether precision immunotherapy tailored to macrophage activation–like syndrome or sepsis-induced immunoparalysis improved organ dysfunction compared with placebo among ...
jamanetwork.com
December 9, 2025 at 11:18 AM
📣 Presenting the 8th #PointOfView, where ESICM specialists provide a 𝘀𝘂𝗺𝗺𝗮𝗿𝘆 𝗼𝗻 𝗮 𝘀𝗲𝗹𝗲𝗰𝘁𝗲𝗱 𝘁𝗼𝗽𝗶𝗰, 𝗳𝗿𝗼𝗺 𝘁𝗵𝗲𝗶𝗿 𝘂𝗻𝗶𝗾𝘂𝗲 𝗽𝗲𝗿𝘀𝗽𝗲𝗰𝘁𝗶𝘃𝗲!

Prepared by #ESICM #SISSection ⏩ 𝗣𝗿𝗲𝗰𝗶𝘀𝗶𝗼𝗻 𝗜𝗺𝗺𝘂𝗻𝗼𝘁𝗵𝗲𝗿𝗮𝗽𝘆 𝘁𝗼 𝗜𝗺𝗽𝗿𝗼𝘃𝗲 𝗦𝗲𝗽𝘀𝗶𝘀 𝗢𝘂𝘁𝗰𝗼𝗺𝗲𝘀 – 𝗧𝗵𝗲 𝗜𝗺𝗺𝘂𝗻𝗼𝗦𝗲𝗽 𝗥𝗮𝗻𝗱𝗼𝗺𝗶𝘇𝗲𝗱 𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗧𝗿𝗶𝗮𝗹

Read the paper here! 👇
Systemic Inflammation and Sepsis - ESICM
The Systemic Inflammation and Sepsis section offers education and research on sepsis, antimicrobial stewardship, and severe infections in critical care.
loom.ly
March 9, 2026 at 3:02 PM
Feed: "Voice for Infection Prevention"
By: Jhutcherson on Friday, March 6, 2026
Adopting Precision Immunotherapy for Improved Sepsis Outcomes: Insights from the ImmunoSep Trial
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voiceforip.com
March 7, 2026 at 1:59 PM
Feed: "Medical News, Health News Latest, Medical News Today - Medical Dialogues |"
By: Medha Baranwal on Wednesday, December 10, 2025
Precision Immunotherapy Improves Organ Function in Sepsis: ImmunoSep Trial
Greece: The ph
medicaldialogues.in
December 10, 2025 at 4:43 AM
EvidenceAlerts | Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial. www.evidencealerts.com/Social/Artic...
EvidenceAlerts | Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial.
www.evidencealerts.com
January 3, 2026 at 12:55 PM
Targeted precision therapy for sepsis! Is it here? • ImmunoSep trial shows impressive results ... until day 90 anyway
Targeted precision therapy for sepsis! Is it here?
ImmunoSep trial shows impressive results ... until day 90 anyway
www.pulmccm.org
December 17, 2025 at 2:28 PM