#Lipid-Lowering
Intensive vs More Intensive Lipid-Lowering Therapy in Statin-Naive Patients jamanetwork.com/journals/jam...

Can coronary atherosclerosis actually regress?

FLOWPROMOTE trial analysis, published in JAMA Cardiology, shows remarkable coronary plaque regression with intensive LDL-C lowering.
Intensive vs More Intensive Lipid-Lowering Therapy in Statin-Naive Patients
This secondary analysis of the FLOWPROMOTE randomized clinical trial investigates if more intensive lipid-lowering therapy leads to greater regression of coronary atherosclerotic plaque across the ent...
jamanetwork.com
November 2, 2026 at 4:00 AM
#Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 years—from early #statin trials to today's longer-acting, less frequently dosed therapies, some of which may eventually require only one or two doses a year youtube.com/watch?v=atCH...
#LDL
#EndoSky #CardioSky
25 Years of Lipid Medicine
YouTube video by The Lancet
youtube.com
October 29, 2026 at 3:42 PM
More intensive vs intensive statin therapy in statin-naive stable CAD (FLOWPROMOTE secondary analysis, n=104, 18 mo)

Rosuvastatin 40 + ezetimibe vs atorvastatin 40:
LDL-C: 42.5 vs 69.5 mg/dL
Total plaque volume: −69.8 vs −39.0 mm³ (difference −30.9 mm³, P=.02)

JAMA Cardiol
Intensive vs More Intensive Lipid-Lowering Therapy and Plaque… · CurrentCardio
Randomized controlled trial · 104 patients · JAMA Cardiol, 2026. This secondary analysis of the FLOWPROMOTE randomized clinical trial demonstrated that in statin-naive patients with CAD, more intensiv...
currentcardio.com
October 31, 2026 at 8:42 AM
Lena E. Tran, MD, and Joshua A. Beckman, MD, examine the shifting paradigm in medical management of PAD by reviewing lipid-lowering, antithrombotic, and cardiometabolic therapies, as well as the growing emphasis on comprehensive, guideline-directed care. https://ow.ly/LXKB50ZZRx5
October 22, 2026 at 7:10 PM
Patients with high-risk #diabetes or #atherosclerosis but no prior #stroke or myocardial infarction experience improved overall survival when evolocumab is added to background lipid-lowering therapy.

https://bit.ly/4ysg2G5
Evolocumab Lowers Mortality in High-Risk Patients Without Prior Stroke or MI
Adding evolocumab to lipid-lowering therapy reduces all-cause mortality in high-risk patients without a history of myocardial infarction or stroke.
www.thecardiologyadvisor.com
October 20, 2026 at 6:20 PM
New publication: Early lipid-lowering strategies after acute coronary syndrome: strike strong or start smart?. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/42667313/
#CVRCBern
October 20, 2026 at 10:02 AM
ICYMI - 25 Years of Lipid Medicine youtube.com/watch?v=atCH...
Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 years—from early statin trials to today's longer-acting, less frequently dosed therapies.
#statins #LDL #cholesterol #PCSK9 inhibitors

#CardioSky
25 Years of Lipid Medicine
YouTube video by The Lancet
youtube.com
October 16, 2026 at 12:17 PM
Cardiometabolic Disease Market: Advanced Lipid-Lowering Treatments and Cholesterol Control

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Email:https://straitsresearch.com/report/cardiometabolic-disease-market
October 15, 2026 at 11:56 AM
Editas clears Australian regulatory approval to start Phase 1/2 trial of EDIT-401, an in vivo gene editor for hyperlipidaemia. First clinical data from the Strive study could reshape lipid-lowering therapeutics.
Editas Medicine clears first hurdle for EDIT-401 hyperlipidaemia trial
Editas has received ethics and regulatory approval in Australia to begin its Phase 1/2 Strive trial of in vivo gene editor EDIT-401 in
biotech.disruptsmedia.com
October 13, 2026 at 6:45 AM
#Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 years—from early #statin trials to today's longer-acting, less frequently dosed therapies, some of which may eventually require only one or two doses a year youtube.com/watch?v=atCH...
#LDL #CVD
#MedSky #CardioSky
25 Years of Lipid Medicine
YouTube video by The Lancet
youtube.com
October 11, 2026 at 10:21 AM
Read more about the evolution of novel pharmacological approaches for lipid lowering during the first quarter of the 21st century
thelancet.com/journals/lan...
#LDL #cholesterol #cardiovascular #disease #prevention

#MedSky #EndoSky #CardioSky
October 11, 2026 at 10:21 AM
Inflammation and endothelial dysfunction in the trigeminovascular system are the suggested underlying mechanisms. Statins, beyond their lipid-lowering effects, exhibit pleiotropic properties including anti-inflammatory, antioxidative, and endothelial-modulating effects, which may (🧵 2/9)
October 10, 2026 at 8:32 AM
❤️🩺 Toxic lipids may contribute to heart and kidney damage in Cardiovascular-Kidney-Metabolic Syndrome (CKMS). This review highlights their role in disease progression and the potential of targeted lipid-lowering therapies. 🔬 #CKMS
mdpi.com/2227-9059/12...
October 8, 2026 at 12:12 AM
Colestipol Market Opens New Growth Pathways in Cardiovascular Care Through 2034

The global Colestipol Market was valued at US$ 158.52 million in 2025 and is expected to reach US$ 202.46 million by 2034, registering a CAGR of 2.76% during 2026–2034. Colestipol is a bile acid sequestrant used to…
Colestipol Market Opens New Growth Pathways in Cardiovascular Care Through 2034
The global Colestipol Market was valued at US$ 158.52 million in 2025 and is expected to reach US$ 202.46 million by 2034, registering a CAGR of 2.76% during 2026–2034. Colestipol is a bile acid sequestrant used to help reduce elevated cholesterol levels by binding bile acids in the digestive tract and promoting their elimination. Its established role in lipid management, continued demand for cholesterol-lowering therapies, and availability through pharmaceutical channels are supporting the market.
www.news24.ph
October 8, 2026 at 6:37 AM
"the research found that post-menopausal women [with Type 1 diabetes] had a higher risk of retinopathy, cardiovascular disease, neuropathy, falls, and moderate-to-severe depressive symptoms.

They were also less likely to have been prescribed antihypertensive and lipid-lowering medications."
October 1, 2026 at 8:43 PM
Dr. Ben Lidgard discusses "Lipid Lowering in CKD: The Nephrologist's Role" in his Grand Rounds presentation @uwnephrology.bsky.social @uwdeptmedicine.bsky.social
#nephsky #kidney #CKD #Lipid #cholesterol

youtu.be/Qq5BXEbhF2k?...
Benjamin Lidgard, MD - Lipid Lowering In CKD: The Nephrologist’s Role
YouTube video by University of Washington Division of Nephrology
youtu.be
September 30, 2026 at 6:02 PM
What’s the future of #CAD #pharmacotherapy?

This review details novel lipid‑lowering agents, anti‑inflammatory therapies, metabolic modulators, & precision medicine approaches, charting path toward safer, more effective CAD treatments #Cardiology #CVIA
#OpenAccess: cvia-journal.org/advances-in-...
September 28, 2026 at 7:48 AM
Ophthopedia Update: Potential protective associations of antidiabetic and lipid-lowering therapies with retinal vein occlusion risk: a systematic review and meta-analysis: Eye, Published online: 24 September 2026; doi:10.1038/s41433-026-04904-4Potential… #Ophthalmology #Eye #Ophthotwitter
Potential protective associations of antidiabetic and lipid-lowering therapies with retinal vein occlusion risk: a systematic review and meta-analysis
Eye, Published online: 24 September 2026; doi:10.1038/s41433-026-04904-4Potential protective associations of antidiabetic and lipid-lowering therapies with retinal vein occlusion risk: a systematic review and meta-analysis
dlvr.it
September 25, 2026 at 2:07 AM
Lipid lowering effects of Fucus vesiculosus and Phytolacca berry extracts: An alternative approach of treating hypertriglyceridemia https://www.biorxiv.org/content/10.64898/2026.09.18.752646v1
September 25, 2026 at 1:00 AM
Lipid lowering effects of Fucus vesiculosus and Phytolacca berry extracts: An alternative approach of treating hypertriglyceridemia https://www.biorxiv.org/content/10.64898/2026.09.18.752646v1
September 25, 2026 at 1:00 AM
Researchers gave mice pemafibrate, a lipid-lowering drug, from 7 days before a temporary brain artery blockage through 2 days after. At the highest dose, average stroke-damaged tissue volume was about half that seen without the drug.
September 23, 2026 at 12:15 PM
#Cholesterol-lowering medicine has changed almost beyond recognition over the past 25 years — from early #statin trials to today's longer-acting, less frequently dosed therapies, some of which may eventually require only one or two doses a year www.youtube.com/watch?v=atCH...
#LDL #ASCVD

#EndoSky
25 Years of Lipid Medicine
YouTube video by The Lancet
www.youtube.com
September 23, 2026 at 8:35 AM