#LongTREC
Fantastic new research just published in Scientific Data by #longTREC researchers Carmen Lafuente Sanz, France Denoeud and Jean-Marc Aury. So much of what lives in the ocean is still missing from our reference databases!

www.nature.com/articles/s41...
Long-read metagenomic and metatranscriptomic datasets from marine plankton - Scientific Data
Scientific Data - Long-read metagenomic and metatranscriptomic datasets from marine plankton
www.nature.com
September 28, 2026 at 3:09 PM
New in Nature Communications from #LongTREC researchers @fabianjetzinger.bsky.social , Stefan Götz & @anaconesa.bsky.social: how should biological replicates be handled when reconstructing transcriptomes? Open access and must-read! 🧬

#LongReadSequencing #RNAseq #Transcriptomics
🎉 New paper from our lab in Nature Comms!
We compare 2 strategies—Join & Call vs Call & Join—across PacBio and ONT data, tissues, and 6 lrRNAseq transcript reconstruction tools. Take away:
👉Join & Call 4 novel isoforms
👉Call & Join 4 2 obtain highly replicated signals.
www.nature.com/articles/s41...
Handling biological replicates in long-read RNA sequencing data by joining or not joining - Nature Communications
When combining long-read RNA sequencing data from multiple samples, transcripts can be identified either before or after merging. This study shows that neither approach is universally optimal and prov...
www.nature.com
September 2, 2026 at 11:32 AM
Outreach matters to us. LongTREC fellow Satrio ran a two-hour session for undergraduate biology students at Universitas Pendidikan Indonesia on sequencing and nanopore technology.

Talk: "Nanopore Sequencing: Anything, Anyone, Anywhere". #LongTREC
August 14, 2026 at 3:14 PM
More exciting work just published by
#LongTREC researchers. The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance.

Four case studies. Four species. One clear message: long reads can help fix allele imbalance.

Go read it!

academic.oup.com/nargab/artic...
The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance
Abstract. Inaccurate allele and gene expression counts due to map bias and genome ambiguity lead to high false positive and false negative rates in studies
academic.oup.com
August 6, 2026 at 3:02 PM
Exciting new tool just published by #LongTREC researchers Nadja Nolte, Marko Petek, and Kristina Gruden.

LongPolyASE is out in Plant Methods, an end-to-end framework for allele-specific gene and isoform analysis from long-read RNA-seq.

link.springer.com/article/10.1...
Login Page
link-springer-com.insb.bib.cnrs.fr
August 6, 2026 at 3:00 PM
And to close, the one who made it all possible. 🌅

Closing keynote: Prof. Ana Conesa on SQANTIverse, a unifying framework for long-read transcriptomics.
LongTREC coordinator, VALT organiser, and a field-shaper for years. No one better to end on.
Thank you, Ana. 💙

#VALT2026 #LongReads #SQANTI
July 1, 2026 at 3:04 PM
Day 2 is underway! ☀️
We're opening this morning with a keynote from Prof. Matthew Ritchie (WEHI): "Benchmarking and analysing long-read RNA-sequencing data with LongBench and FLAMES."
Rigorous benchmarking and the tools to act on it.
#VALT2026 #LongReads #Transcriptomics #LongTREC
June 30, 2026 at 7:07 AM
Now at #VALT2026: the Oxford Nanopore workshop. Aino Järvelin kicks off, then Jonathan Göke on the cDNA beta test and library prep for long-read RNA-seq, and Christoph Dieterich on RNA modification co-occurrence from direct RNA-seq. #LongTReC #lrRNAseq
June 29, 2026 at 12:40 PM
⚡ Flash talks at #VALT2026 ⚡: four quickfire takes on building and annotating transcriptomes with long reads: transcript-end detection in FLAIR4, the non-coding transcriptome, structural gene prediction, and tissue-specific isoform atlases. #LongTREC #lrRNAseq
June 29, 2026 at 11:08 AM
Next at #VALT2026: Anastasiya Grinko on expanding the known transcriptome at the single-cell level, using long reads to surface novel isoforms in macrophages and monocytes from diseased tissues. #LongTREC #lrRNAseq #SingleCellLongRead
June 29, 2026 at 10:50 AM
Next at #VALT2026: Juan Francisco Cervilla on evaluating gene fusion expression in B-ALL at single-cell resolution, using long reads to resolve fusion transcripts cell by cell. #LongTREC #lrRNAseq #FusionGenes
June 29, 2026 at 10:24 AM
Next at #VALT2026: Maximillian Gabriel Marin on personalized transcriptome annotation, exposing reference-biased isoforms and how structural variation shapes human transcript diversity. #LongTREC #lrRNAseq
June 29, 2026 at 10:00 AM
ext at #VALT2026: Fairlie Reese on long-read transcriptomics across a genetically diverse human cohort, revealing ancestry bias in gene annotation. Non-European transcripts are underrepresented in current references. #LongTREC #lrRNAseq
June 29, 2026 at 9:43 AM
Next at #VALT2026: Mahmud Sami Aydin on de novo transcript construction and isoform clustering from gene clusters. Reference-free assembly of paralogous regions, where reference-guided methods tend to struggle. #LongTREC #lrRNAseq #DeNovoTranscriptReconstruction
June 29, 2026 at 8:41 AM
Next at #VALT2026: Pablo Angulo on long-read sequencing, uncovering transcriptional allele-specific dosage compensation in aneuploidy. Phasing expression to its allele of origin to see how cells buffer altered chromosome dosage. #LongTREC #lrRNAseq #Aneuploidy #AlleleSpecificExspression
June 29, 2026 at 8:17 AM
Continuing the epigenome theme at #VALT2026: Tianyuan Liu on SQANTI-Epi, integrating Fiber-seq with long-read RNA-seq to link chromatin state to isoform regulation.
#LongTREC #VALT2026 #lrRNAseq #transcriptomics
June 29, 2026 at 8:07 AM
The brilliant Angela Brooks kicks off our keynotes at #VALT2026: multi-omic long-read sequencing and the contribution of chromatin to RNA transcription and processing. Tying chromatin state to isoform regulation at single-molecule resolution. #LongTREC #lrRNAseq
June 29, 2026 at 7:43 AM
📢 VALT Symposium — 29 June 2026, Valencia
📍 Botanical Garden, Universitat de València — stay on marked paths

☀️ Hot & sunny: sunglasses & sunscreen

🌱 Bring a reusable bottle — refill stations available

#LongTREC #LongReadTranscriptomics #VALT2026 #Valencia
June 27, 2026 at 7:20 AM
We are pleased to announce that the abstract review process for the #VALT Symposium has been completed.

All submitters have received notification of their submission outcome!

The full list of accepted contributions will be published soon in the #VALT website (longtrec.eu/VALT/).
VALT – LongTREC
longtrec.eu
April 15, 2026 at 2:09 PM
Today is the last day to submit your abstract for the #VALT symposium.

Don’t miss the chance to contribute with your work and be part of this international event.

🔗 Submit your abstract here: longtrec.eu/VALT/

You have until the end of today ☀️
VALT – LongTREC
Check your inbox or spam folder to confirm your subscription.
longtrec.eu
March 31, 2026 at 10:29 AM
#VALT symposium website is active again! Do you want to know who's coming? 👉 longtrec.eu/valt/
📨Accepting abstracts for oral and poster presentation!
VALT – LongTREC
Check your inbox or spam folder to confirm your subscription.
longtrec.eu
February 19, 2026 at 9:20 AM
On International Day of Women and Girls in Science, we celebrate the brilliant women across LongTREC — from PhD researchers to supervisors, project managers, counsellors, trainers and partners. Your work drives our science forward every day. #WomenInScience #LongTREC #STEM
February 11, 2026 at 5:49 PM
We can't wait to see you in Valencia this summer at VALT! Check out our exciting Line up of speakers below. Interested in sharing your work on #LongReadTranscriptomics ? Abstract submission deadline 📅 March 31st.
#LongTREC #LongReadSequencing #Nanopore #Pacbio
January 29, 2026 at 12:37 PM
The registration to the #VALT symposium is open! longtrec.eu/valt/ Sign up to receive updates!

Abstract submission deadline 📅 March 31st.

We can't wait to see you in Valencia this summer for the most exciting Long Read Transcriptomics conference this year.
VALT – LongTREC
Check your inbox or spam folder to confirm your subscription.
longtrec.eu
January 22, 2026 at 8:53 AM
New preprint on #LongReadTranscriptomics from @fabianjetzinger.bsky.social #LongTREC. How you combine replicates in long-read experiments matters more than you think — it shapes detection of both known and novel transcripts! A must read for Long read RNA-seq users!
www.biorxiv.org/content/10.6...
To join or not to join: handling biological replicates in long-read RNA sequencing data
Long-read RNA sequencing (lrRNA-seq) has revolutionized transcriptomics facilitating the study of alternative splicing and resulting in identification of thousands of novel transcripts. While isoform ...
www.biorxiv.org
December 15, 2025 at 8:25 AM