#Nanopore
Today, the NHS Respiratory Metagenomics Network have published a paper in Nature highlighting practical principles that could support the wider rollout of rapid #metagenomics nanopore sequencing in the future.

https://www.nature.com/articles/s43856-026-01968-x

Oxford Nanopore products are RUO.
November 4, 2026 at 5:43 PM
A new Nature Methods paper from one of our #LongTREC supervisors, @evamarianovoa.bsky.social , and colleagues introduces #tRIBO-seq. It’s a nanopore-based method that reads tRNAs bound to ribosomes while they make protein.

Read the full paper in Nature Methods now to learn more.

#tRNA #Nanopore
November 3, 2026 at 8:57 AM
Interrogating the Escherichia coli Epitranscriptome Via CRISPR Interference and Nanopore Native RNA Sequencing onlinelibrary.wiley.com/doi/10.1002/...
Interrogating the <i>Escherichia coli</i> Epitranscriptome Via CRISPR Interference and Nanopore Native RNA Sequencing
Epitranscriptomics is understudied in bacteria but has the ability to modulate antimicrobial resistance, virulence and pathogenicity. Pitt et al. implement two cutting-edge techniques: CRISPR interfe...
onlinelibrary.wiley.com
October 31, 2026 at 8:48 PM
Cryo-EM structure of a protein nanopore reveals lipid acyl chains as integral components pubmed.ncbi.nlm.nih.gov/42962025/ #cryoem
October 31, 2026 at 8:58 PM
Very happy to share that our work (beautifully led by @miemonti.bsky.social and #Hasan) is finally out! 😄We find that tRNAs engaged in actively translating ribosomes significantly differ from the 'total' pool available in the cell, specially upon stress! www.nature.com/articles/s41...
Selective profiling of translationally active tRNAs and their dynamics under stress - Nature Methods
tRIBO-seq distinguishes between ribosome-associated tRNAs and total tRNAs using nanopore sequencing, thus revealing their potentially distinct abundance, modification and fragmentation patterns in var...
www.nature.com
November 2, 2026 at 5:17 PM
Working between my lab, Dominic Byrne, and with CASE partners Portal Biotech, you will be studying virus replication using cutting edge protein nanopore technology and mass spectrometry!
November 4, 2026 at 11:35 AM
Investigation of Shielding Strategies to Mitigate Noise in Nanopore Recordings https://pubmed.ncbi.nlm.nih.gov/42921128/
November 2, 2026 at 9:48 AM
Dynamic Metal-Organic Tweezer Enables High-Resolution Nanopore Analysis of Steroid Hormones https://pubmed.ncbi.nlm.nih.gov/42937962/
November 2, 2026 at 9:04 AM
Nanopore Sequencing for Epigenetic Decoding: Applications, Analytical Constraints, and Translational Prospects https://pubmed.ncbi.nlm.nih.gov/42941945/
November 2, 2026 at 8:53 AM
🎤 Coming up at #LRUA26!

📅 Wednesday 4 November · 10:55–11:10
📍 Breakout session: Multiomics · Sal X

#LongTREC Doctoral Candidate @tianyuanliu.bsky.social will present:

"SQANTI-EPI: quality control and benchmarking for single-molecule chromatin structure on PacBio and nanopore"

#Multiomics
November 4, 2026 at 9:19 AM
Cryo-EM structure of a protein nanopore reveals lipid acyl chains as integral components https://pubmed.ncbi.nlm.nih.gov/42962025/
November 2, 2026 at 8:42 AM
Not all biological answers lie in the DNA sequence. In this knowledge exchange, we explore how gold-standard Oxford Nanopore methylation sequencing reveals hidden insights that traditional methods miss—all from a single run.

https://bit.ly/4j7E45j
November 2, 2026 at 2:22 PM
Programmable Multisite Recognition Enables Amplification-Free Nanopore Detection of Mycobacterium tuberculosis in Sputum and Plasma https://pubmed.ncbi.nlm.nih.gov/42917048/
November 2, 2026 at 10:21 AM
Improving All-Atom Molecular Dynamics Models for Quantitative Prediction of Nanopore Blockade Current https://pubmed.ncbi.nlm.nih.gov/42917281/
November 2, 2026 at 10:10 AM
Probe-Free, Primer-Programmed Amplicon Encoding Enables Nanopore-Based Multiplex Detection With Deep Learning Decoding https://pubmed.ncbi.nlm.nih.gov/42921872/
November 2, 2026 at 9:37 AM
NPlasmid-seq: Cas9-encoded terminal signatures enable molecule-level nanopore quality control of vector and IVT-template plasmids https://www.biorxiv.org/content/10.64898/2026.11.02.763549v1
November 3, 2026 at 2:46 PM
NPlasmid-seq: Cas9-encoded terminal signatures enable molecule-level nanopore quality control of vector and IVT-template plasmids https://www.biorxiv.org/content/10.64898/2026.11.02.763549v1
November 3, 2026 at 2:46 PM
A reference mitogenome for the yellow-tailed woolly monkey (Lagothrix flavicauda) using Oxford Nanopore sequencing shows no evidence for adaptation to high elevations https://pubmed.ncbi.nlm.nih.gov/42972244/
November 4, 2026 at 10:23 AM
Cryo-EM structure of a protein nanopore reveals lipid acyl chains as integral components pubmed.ncbi.nlm.nih.gov/42962025/ #cryoem
October 31, 2026 at 8:58 PM
Paul sounds pretty furious about @nanoporetech.com massively jacking up the price of its sequencers 10-20 fold and is now looking at Chinese sequencers such as Qitan #iBOL2026
November 3, 2026 at 2:59 AM
📝 Nanopore RNA sequencing reveals new patterns associated with RNA modifications
✍️ RNA-Seq Blog
Nanopore RNA sequencing reveals new patterns associated with RNA modifications
Article de RNA-Seq Blog
www.rna-seqblog.com
October 30, 2026 at 7:55 AM
We have one more PhD opportunity for October 2027 start! This is open to international applicants, deadline Dec 4th. NWD DLA programme: Uncovering regulation of viral polyprotein cleavage using protein nanopore technology. See below for more details: www.findaphd.com/phds/project...
November 4, 2026 at 11:35 AM
Join Kimberley Billingsley as she discusses how a large-scale Oxford Nanopore WGS resource was built across multiple postmortem brain cohorts to reveal structural variants and repeat expansions linked to Alzheimer's disease and related dementias.

https://bit.ly/3UkAb30
November 3, 2026 at 12:56 PM
Do you fancy taking to the stage at #nanoporeconf to share your latest Oxford Nanopore-based research? Be sure to submit your abstract before 15th January to be in with a chance! 

Submit your abstract here: https://bit.ly/4ij5iF6
November 2, 2026 at 6:59 PM
The Netherlands is transforming the genomic antimicrobial resistance (AMR) surveillance by integrating resistance plasmid analysis using “PlasmidNL” to monitor plasmid outbreaks and spread. AND YOU CAN USE IT TOO!
#AMR #Genomics #surveillance #Nanopore #plasmids #CPE #MRSA #PlasmidOutbreaks #ONT
October 30, 2026 at 6:54 AM