Nature research paper: A methanogen hydrolase reveals the structure of archaeal peptidoglycan
go.nature.com/4xN3B7j
go.nature.com/4xN3B7j
A methanogen hydrolase reveals the structure of archaeal peptidoglycan - Nature
ArmA from Methanobrevibacter smithii, a dominant member of the human gut microbiome, is identified and characterized as a glycosyl hydrolase specific for cleaving the cell wall of methanogens, revealing an unsuspected chemical structure of archaeal peptidoglycan that includes a previously unidentified sugar.
go.nature.com
September 30, 2026 at 9:47 AM
Nature research paper: A methanogen hydrolase reveals the structure of archaeal peptidoglycan
go.nature.com/4xN3B7j
go.nature.com/4xN3B7j
A methanogen hydrolase reveals the structure of archaeal peptidoglycan www.nature.com/articles/s41... #jcampubs
A methanogen hydrolase reveals the structure of archaeal peptidoglycan - Nature
ArmA from Methanobrevibacter smithii, a dominant member of the human gut microbiome, is identified and characterized as a glycosyl hydrolase specific for cleaving the cell wall of methanogens, reveali...
www.nature.com
September 24, 2026 at 1:58 PM
A methanogen hydrolase reveals the structure of archaeal peptidoglycan www.nature.com/articles/s41... #jcampubs
A methanogen hydrolase reveals the structure of archaeal peptidoglycan
#Archaea #Methanogens #methane #GutMicrobiota #Microbiome #MicroSky #ArchaeaSky
@nature.com
doi.org/10.1038/s415...
#Archaea #Methanogens #methane #GutMicrobiota #Microbiome #MicroSky #ArchaeaSky
@nature.com
doi.org/10.1038/s415...
A methanogen hydrolase reveals the structure of archaeal peptidoglycan - Nature
ArmA from Methanobrevibacter smithii, a dominant member of the human gut microbiome, is identified and characterized as a glycosyl hydrolase specific for cleaving the cell wall of methanogens, reveali...
doi.org
September 24, 2026 at 1:36 PM
A methanogen hydrolase reveals the structure of archaeal peptidoglycan
#Archaea #Methanogens #methane #GutMicrobiota #Microbiome #MicroSky #ArchaeaSky
@nature.com
doi.org/10.1038/s415...
#Archaea #Methanogens #methane #GutMicrobiota #Microbiome #MicroSky #ArchaeaSky
@nature.com
doi.org/10.1038/s415...
A methanogen hydrolase reveals the structure of archaeal peptidoglycan
www.nature.com/articles/s41...
🦠
Shareable link to read the paper: rdcu.be/FJXrUPAdeswa
www.nature.com/articles/s41...
🦠
Shareable link to read the paper: rdcu.be/FJXrUPAdeswa
A methanogen hydrolase reveals the structure of archaeal peptidoglycan - Nature
ArmA from Methanobrevibacter smithii, a dominant member of the human gut microbiome, is identified and characterized as a glycosyl hydrolase specific for cleaving the cell wall of methanogens, reveali...
www.nature.com
September 24, 2026 at 12:38 PM
A methanogen hydrolase reveals the structure of archaeal peptidoglycan
www.nature.com/articles/s41...
🦠
Shareable link to read the paper: rdcu.be/FJXrUPAdeswa
www.nature.com/articles/s41...
🦠
Shareable link to read the paper: rdcu.be/FJXrUPAdeswa
🚨🧪 Paper alert: Archaeal cell wall structure revised!
An international research team including #CIBSS members identified a first hydrolase specific to archaeal peptidoglycan, allowing them profound insights into its structure.
🔗 Read more 👇
#Archaea #Peptidoglycan @pasteur.fr
An international research team including #CIBSS members identified a first hydrolase specific to archaeal peptidoglycan, allowing them profound insights into its structure.
🔗 Read more 👇
#Archaea #Peptidoglycan @pasteur.fr
A methanogen hydrolase reveals the structure of archaeal peptidoglycan - Nature
ArmA from Methanobrevibacter smithii, a dominant member of the human gut microbiome, is identified and characterized as a glycosyl hydrolase specific for cleaving the cell wall of methanogens, reveali...
www.nature.com
September 24, 2026 at 12:19 PM
🚨🧪 Paper alert: Archaeal cell wall structure revised!
An international research team including #CIBSS members identified a first hydrolase specific to archaeal peptidoglycan, allowing them profound insights into its structure.
🔗 Read more 👇
#Archaea #Peptidoglycan @pasteur.fr
An international research team including #CIBSS members identified a first hydrolase specific to archaeal peptidoglycan, allowing them profound insights into its structure.
🔗 Read more 👇
#Archaea #Peptidoglycan @pasteur.fr
ArmA is conserved in all PG-bearing methanogens and beautifully localizes at the division site. Our deletion mutant confirms that this enzyme is required for cell division, hydrolysing archaeal PG to complete cytokinesis and cell separation 6/9
September 23, 2026 at 3:19 PM
ArmA is conserved in all PG-bearing methanogens and beautifully localizes at the division site. Our deletion mutant confirms that this enzyme is required for cell division, hydrolysing archaeal PG to complete cytokinesis and cell separation 6/9
While peptidoglycan (PG) is an essential and near-universal feature of Bacteria, it is largely absent in Archaea. A notable exception is a large clade of methane-producing archaea, which possess a cell wall with a distinct type of PG (also known as pseudomurein) 2/9
September 23, 2026 at 3:19 PM
While peptidoglycan (PG) is an essential and near-universal feature of Bacteria, it is largely absent in Archaea. A notable exception is a large clade of methane-producing archaea, which possess a cell wall with a distinct type of PG (also known as pseudomurein) 2/9
In 2023, we already reclassified Methanobrevibacter using genomes via #SeqCode. However, that reclassification is not valid under the current International Code of Nomenclature of Prokaryotes (ICNP). In our new IJSEM paper, we fixed this📄🔬
#methanogens #methane
#methanogens #methane
September 18, 2026 at 7:54 AM
In 2023, we already reclassified Methanobrevibacter using genomes via #SeqCode. However, that reclassification is not valid under the current International Code of Nomenclature of Prokaryotes (ICNP). In our new IJSEM paper, we fixed this📄🔬
#methanogens #methane
#methanogens #methane
When genus deserves to be a family 🦠🔬
Recent phylogenomic analyses showed that the genus Methanobrevibacter is severely underclassified. We propose reclassifying it into a family, Methanobrevibacteraceae consisting of 11 genera.
@microbiologysociety.org
#MicroSky #Archaea
doi.org/10.1099/ijse...
Recent phylogenomic analyses showed that the genus Methanobrevibacter is severely underclassified. We propose reclassifying it into a family, Methanobrevibacteraceae consisting of 11 genera.
@microbiologysociety.org
#MicroSky #Archaea
doi.org/10.1099/ijse...
September 18, 2026 at 7:54 AM
When genus deserves to be a family 🦠🔬
Recent phylogenomic analyses showed that the genus Methanobrevibacter is severely underclassified. We propose reclassifying it into a family, Methanobrevibacteraceae consisting of 11 genera.
@microbiologysociety.org
#MicroSky #Archaea
doi.org/10.1099/ijse...
Recent phylogenomic analyses showed that the genus Methanobrevibacter is severely underclassified. We propose reclassifying it into a family, Methanobrevibacteraceae consisting of 11 genera.
@microbiologysociety.org
#MicroSky #Archaea
doi.org/10.1099/ijse...
It’s International Microorganism Day! For a third year running, some of our Champions have told us about their favourite microbes and our very talented Champion, Eliza Wolfson, has brought these to life with her illustrations!
@eliza-coli.bsky.social @femsmicro.org
@eliza-coli.bsky.social @femsmicro.org
September 17, 2026 at 8:00 AM
It’s International Microorganism Day! For a third year running, some of our Champions have told us about their favourite microbes and our very talented Champion, Eliza Wolfson, has brought these to life with her illustrations!
@eliza-coli.bsky.social @femsmicro.org
@eliza-coli.bsky.social @femsmicro.org
I will present my poster PS1.05.215 on the #evolution of the phylum Methanobacteriota and the elevation of the genus Methanobrevibacter to the family level on Monday, 17th August, from 10 to 11 am in the Animal Microbiomes session.
#MicrobialEcology #taxonomy #methanogens
#MicrobialEcology #taxonomy #methanogens
August 16, 2026 at 12:35 AM
I will present my poster PS1.05.215 on the #evolution of the phylum Methanobacteriota and the elevation of the genus Methanobrevibacter to the family level on Monday, 17th August, from 10 to 11 am in the Animal Microbiomes session.
#MicrobialEcology #taxonomy #methanogens
#MicrobialEcology #taxonomy #methanogens
Multi-omics and functional validation reveal that Methanobrevibacter-derived L-3-aminoisobutyrate alleviates subclinical mastitis in dairy goats via the HSPA1B-p65 signaling pathway
#microbiology #methanogens #microbiome #MicroSky
@microbiomej.bsky.social
link.springer.com/article/10.1...
#microbiology #methanogens #microbiome #MicroSky
@microbiomej.bsky.social
link.springer.com/article/10.1...
Multi-omics and functional validation reveal that Methanobrevibacter-derived L-3-aminoisobutyrate alleviates subclinical mastitis in dairy goats via the HSPA1B-p65 signaling pathway - Microbiome
Background Subclinical mastitis (SCM) is prevalent in dairy livestock and compromises milk quality and lactation performance. Although often attributed to bacterial infection, many cases lack identifi...
link.springer.com
July 26, 2026 at 10:21 AM
Multi-omics and functional validation reveal that Methanobrevibacter-derived L-3-aminoisobutyrate alleviates subclinical mastitis in dairy goats via the HSPA1B-p65 signaling pathway
#microbiology #methanogens #microbiome #MicroSky
@microbiomej.bsky.social
link.springer.com/article/10.1...
#microbiology #methanogens #microbiome #MicroSky
@microbiomej.bsky.social
link.springer.com/article/10.1...
« Un français sur 2 a une bactérie intestinale appelée Methanobrevibacter smithii capable de transformer l’hydrogène en méthane. Ces sujets peuvent produire une flamme bleue en allumant leurs pets et leurs selles flottent sur l’eau. »
Je cherche mon briquet.
Je cherche mon briquet.
July 14, 2026 at 12:09 PM
« Un français sur 2 a une bactérie intestinale appelée Methanobrevibacter smithii capable de transformer l’hydrogène en méthane. Ces sujets peuvent produire une flamme bleue en allumant leurs pets et leurs selles flottent sur l’eau. »
Je cherche mon briquet.
Je cherche mon briquet.
Treating Methane SIBO (IMO) may reduce the risk of colorectal cancer, since methanobrevibacter smithii is associated with increased risk of colorectal cancer via promoting the growth of bacteria such as Fusobacterium nucleatum pmc.ncbi.nlm.nih.gov/articles/PMC...
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pmc.ncbi.nlm.nih.gov
June 19, 2026 at 10:13 PM
Treating Methane SIBO (IMO) may reduce the risk of colorectal cancer, since methanobrevibacter smithii is associated with increased risk of colorectal cancer via promoting the growth of bacteria such as Fusobacterium nucleatum pmc.ncbi.nlm.nih.gov/articles/PMC...
歯石DNAから読み解く、過去の日本人と口腔内微生物の関わり～江戸時代のお歯黒痕跡と歯周病関連古細菌の系統分布に着目～ | 研究成果 | ニュース | 新潟大学
さらに、歯周病関連古細菌 Methanobrevibacter oralis（以下、M. oralis）（注2）の系統解析では、過去の研究でお歯黒痕跡が報告されていた女性個体に由来するM. …
www.niigata-u.ac.jp/news/2026/11...
さらに、歯周病関連古細菌 Methanobrevibacter oralis（以下、M. oralis）（注2）の系統解析では、過去の研究でお歯黒痕跡が報告されていた女性個体に由来するM. …
www.niigata-u.ac.jp/news/2026/11...
歯石DNAから読み解く、過去の日本人と口腔内微生物の関わり～江戸時代のお歯黒痕跡と歯周病関連古細菌の系統分布に着目～ | 研究成果 | ニュース | 新潟大学
東邦大学、東京大学、農業・食品産業技術総合研究機構、国際医療福祉大学、聖マリアンナ医科大学、九州大学、国立科学博物館、日本大学、土井ヶ浜遺跡・人類学ミュージアム、新潟医療福祉大学、鎌倉女子大学、沖縄県立埋蔵文化財センター […]
www.niigata-u.ac.jp
June 9, 2026 at 1:07 AM
歯石DNAから読み解く、過去の日本人と口腔内微生物の関わり～江戸時代のお歯黒痕跡と歯周病関連古細菌の系統分布に着目～ | 研究成果 | ニュース | 新潟大学
さらに、歯周病関連古細菌 Methanobrevibacter oralis（以下、M. oralis）（注2）の系統解析では、過去の研究でお歯黒痕跡が報告されていた女性個体に由来するM. …
www.niigata-u.ac.jp/news/2026/11...
さらに、歯周病関連古細菌 Methanobrevibacter oralis（以下、M. oralis）（注2）の系統解析では、過去の研究でお歯黒痕跡が報告されていた女性個体に由来するM. …
www.niigata-u.ac.jp/news/2026/11...
Recently, we renamed this lineage as Methanovirga to highlight their exclusivity to the termite gut flagellates. Long evolution as endosymbionts changed their genomes—they have decreased coding density, many pseudogenes, & degraded biosynthetic pathways.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Convergent evolution of intestinal lineages in the phylum Methanobacteriota - Microbiome
Background Representatives of the phylum Methanobacteriota occur in various anoxic environments, but only members of the genera Methanosphaera and Methanobrevibacter exclusively colonize the digestive...
link.springer.com
May 27, 2026 at 11:51 AM
Recently, we renamed this lineage as Methanovirga to highlight their exclusivity to the termite gut flagellates. Long evolution as endosymbionts changed their genomes—they have decreased coding density, many pseudogenes, & degraded biosynthetic pathways.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Archaea are single-celled life forms that prospered when the Earth was hot. You can still find them in extreme environments like hot springs, hydrothermal vents and salt lakes. Turns out they also make methane in your gut!
Now when I fart, I'll blame archaea.
en.wikipedia.org/wiki/Methano...
Now when I fart, I'll blame archaea.
en.wikipedia.org/wiki/Methano...
Methanobrevibacter smithii - Wikipedia
en.wikipedia.org
May 10, 2026 at 3:23 PM
Archaea are single-celled life forms that prospered when the Earth was hot. You can still find them in extreme environments like hot springs, hydrothermal vents and salt lakes. Turns out they also make methane in your gut!
Now when I fart, I'll blame archaea.
en.wikipedia.org/wiki/Methano...
Now when I fart, I'll blame archaea.
en.wikipedia.org/wiki/Methano...
Based on phylogenomic and phenotypic evidence, we propose elevating the genus Methanobrevibacter to the rank of family: Methanobrevibacteraceae.
May 4, 2026 at 9:45 AM
Based on phylogenomic and phenotypic evidence, we propose elevating the genus Methanobrevibacter to the rank of family: Methanobrevibacteraceae.
Methanobrevibacter smithii, the archaea that produces methane gas (IMO/methane SIBO) promotes the growth of certain bacteria like Fusobacterium nucleatum that are associated with colorectal cancer.https://pmc.ncbi.nlm.nih.gov/articles/PMC13035836/
May 3, 2026 at 2:31 PM
Methanobrevibacter smithii, the archaea that produces methane gas (IMO/methane SIBO) promotes the growth of certain bacteria like Fusobacterium nucleatum that are associated with colorectal cancer.https://pmc.ncbi.nlm.nih.gov/articles/PMC13035836/
Livestock presence in Kenyan reserves is linked to significant shifts in elephant gut microbiomes, with increases in *Methanobrevibacter* and decreases in *Roseburia*.
https://newsletter.tf/livestock-changes-kenya-elephant-gut-bacteria/
https://newsletter.tf/livestock-changes-kenya-elephant-gut-bacteria/
Livestock in Kenya Reserves Change Elephant Gut Bacteria
New study shows livestock in Kenya's Samburu and Buffalo Springs Reserves are changing gut bacteria in African elephants, with unknown health effects.
newsletter.tf
April 11, 2026 at 3:36 AM
Livestock presence in Kenyan reserves is linked to significant shifts in elephant gut microbiomes, with increases in *Methanobrevibacter* and decreases in *Roseburia*.
https://newsletter.tf/livestock-changes-kenya-elephant-gut-bacteria/
https://newsletter.tf/livestock-changes-kenya-elephant-gut-bacteria/
Christine highlights the dangerous influence of methane on human health, especially on colorectal cancer
Co-cultures of Methanobrevibacter with Fusobacterium nucleatum, Bacteroides fragilis & E. coli
See their recent @natcomms.nature.com paper on this
www.nature.com/articles/s41...
#KNVM2026
Co-cultures of Methanobrevibacter with Fusobacterium nucleatum, Bacteroides fragilis & E. coli
See their recent @natcomms.nature.com paper on this
www.nature.com/articles/s41...
#KNVM2026
April 1, 2026 at 8:19 AM
Christine highlights the dangerous influence of methane on human health, especially on colorectal cancer
Co-cultures of Methanobrevibacter with Fusobacterium nucleatum, Bacteroides fragilis & E. coli
See their recent @natcomms.nature.com paper on this
www.nature.com/articles/s41...
#KNVM2026
Co-cultures of Methanobrevibacter with Fusobacterium nucleatum, Bacteroides fragilis & E. coli
See their recent @natcomms.nature.com paper on this
www.nature.com/articles/s41...
#KNVM2026
Christine about Methanobrevibacter in the human and animal gut, adaptation to specific host (species found depends on host) and to the gut environment (adhesins, signalling vesicles)
See their @natcomms.nature.com paper
www.nature.com/articles/s41...
#KNVM2026
See their @natcomms.nature.com paper
www.nature.com/articles/s41...
#KNVM2026
Targeted isolation of Methanobrevibacter strains from fecal samples expands the cultivated human archaeome - Nature Communications
Here, the authors present a new method for isolating methanogenic archaea from human fecal samples and establish stable archaeal cultures yielding nine previously uncultivated strains, which upon furt...
www.nature.com
April 1, 2026 at 8:09 AM
Christine about Methanobrevibacter in the human and animal gut, adaptation to specific host (species found depends on host) and to the gut environment (adhesins, signalling vesicles)
See their @natcomms.nature.com paper
www.nature.com/articles/s41...
#KNVM2026
See their @natcomms.nature.com paper
www.nature.com/articles/s41...
#KNVM2026
Genomic and phenotypic characterization of a human gut Methanobrevibacter intestini strain G0370_i3 isolated in Gabon
#microbiology #methanogens #archaea #MicroSky
doi.org/10.1080/1746...
#microbiology #methanogens #archaea #MicroSky
doi.org/10.1080/1746...
March 29, 2026 at 11:42 AM
Genomic and phenotypic characterization of a human gut Methanobrevibacter intestini strain G0370_i3 isolated in Gabon
#microbiology #methanogens #archaea #MicroSky
doi.org/10.1080/1746...
#microbiology #methanogens #archaea #MicroSky
doi.org/10.1080/1746...
Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems
#microbiology #methanogens #methane #cancer #ColorectalCancer #MicroSky #ArchaeaSky
@natcomms.nature.com
doi.org/10.1038/s414...
#microbiology #methanogens #methane #cancer #ColorectalCancer #MicroSky #ArchaeaSky
@natcomms.nature.com
doi.org/10.1038/s414...
Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems - Nature Communications
Here, the authors identify widespread disease associations of gut archaea, particularly in colorectal cancer, with further experiments revealing Methanobrevibacter smithii cooperation with cancer-asso...
doi.org
March 15, 2026 at 4:09 PM
Cross-domain metabolic interactions link Methanobrevibacter smithii to colorectal cancer microbial ecosystems
#microbiology #methanogens #methane #cancer #ColorectalCancer #MicroSky #ArchaeaSky
@natcomms.nature.com
doi.org/10.1038/s414...
#microbiology #methanogens #methane #cancer #ColorectalCancer #MicroSky #ArchaeaSky
@natcomms.nature.com
doi.org/10.1038/s414...
Lab co-cultures confirmed it and showed, that Methanobrevibacter also accellerates the growth of Fusobacterium.
Some metabolites these two form together could promote cancer. Others might suppress it.
Some metabolites these two form together could promote cancer. Others might suppress it.
March 11, 2026 at 4:45 PM
Lab co-cultures confirmed it and showed, that Methanobrevibacter also accellerates the growth of Fusobacterium.
Some metabolites these two form together could promote cancer. Others might suppress it.
Some metabolites these two form together could promote cancer. Others might suppress it.