#MedSky🧪 #IDSky #Academicsky #Clinicalresearch #publichealth #Mucosalimmunity Beyong #Gutbrainaxis Intestinal epithelial barrier-integrity is essential for human health, and its disruption induces and exacerbates intestinal inflammatory disorders.
December 23, 2024 at 3:40 AM
#MedSky🧪 #IDSky #Academicsky #Clinicalresearch #publichealth #Mucosalimmunity Beyong #Gutbrainaxis Intestinal epithelial barrier-integrity is essential for human health, and its disruption induces and exacerbates intestinal inflammatory disorders.
Hello Bluesky!
We are very pleased to join you all here and are looking forward to a fun and inspirational time 😃
We are interested in immunology, specifically in the upper airway #ENT #ImmunoSky #MedSky #Mucosalimmunity #AcademicSky
Have a productive day everyone 🤗
We are very pleased to join you all here and are looking forward to a fun and inspirational time 😃
We are interested in immunology, specifically in the upper airway #ENT #ImmunoSky #MedSky #Mucosalimmunity #AcademicSky
Have a productive day everyone 🤗
November 14, 2024 at 9:01 AM
Hello Bluesky!
We are very pleased to join you all here and are looking forward to a fun and inspirational time 😃
We are interested in immunology, specifically in the upper airway #ENT #ImmunoSky #MedSky #Mucosalimmunity #AcademicSky
Have a productive day everyone 🤗
We are very pleased to join you all here and are looking forward to a fun and inspirational time 😃
We are interested in immunology, specifically in the upper airway #ENT #ImmunoSky #MedSky #Mucosalimmunity #AcademicSky
Have a productive day everyone 🤗
#MedSky🧪 #IDSky #ImmunoSky #Mucosalimmunity Overview Sublingual immune cell clusters and #dendriticcell distribution in the oral cavity
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
November 10, 2024 at 4:29 PM
#MedSky🧪 #IDSky #ImmunoSky #Mucosalimmunity Overview Sublingual immune cell clusters and #dendriticcell distribution in the oral cavity
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
#Medsky🧪 #IDsky #immunosky #pedsky #mucosalimmunity #virosky #publichealth Mucosal viral infections elicit long-lived IgA responses through mechanisms that critically depend on type 1 follicular helper T (Tfh1) cells, with site-specific requirements for B cell MHC class II & IFNγ signaling.
December 2, 2025 at 6:03 AM
#Medsky🧪 #IDsky #immunosky #pedsky #mucosalimmunity #virosky #publichealth Mucosal viral infections elicit long-lived IgA responses through mechanisms that critically depend on type 1 follicular helper T (Tfh1) cells, with site-specific requirements for B cell MHC class II & IFNγ signaling.
#MedSky🧪 #IDsky #Immunosky #Mucosalimmunity overview of antiviral immune responses in the oral cavity in common viral infections & their manifestations in the oral mucosa.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Viral infection and antiviral immunity in the oral cavity - Nature Reviews Immunology
The oral mucosa is a critical barrier tissue that is continually exposed to pathogens, but antiviral immune responses in this tissue are poorly understood. Moreover, recent viral outbreaks, including ...
www.nature.com
November 13, 2024 at 6:05 AM
#MedSky🧪 #IDsky #Immunosky #Mucosalimmunity overview of antiviral immune responses in the oral cavity in common viral infections & their manifestations in the oral mucosa.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
#MedSky🧪 #IDsky #PedSky #ImmunoSky #Mucosalimmunity #Antiviral #innateimmune memory in alveolar #macrophages following #SARSCoV2 infection ameliorates secondary influenza A virus disease
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection ameliorates secondary influenza A virus disease
Pathogen encounter can result in epigenetic remodeling that shapes disease caused by heterologous pathogens. Here, we examined innate immune memory in…
www.sciencedirect.com
November 12, 2024 at 8:30 PM
#MedSky🧪 #IDsky #PedSky #ImmunoSky #Mucosalimmunity #Antiviral #innateimmune memory in alveolar #macrophages following #SARSCoV2 infection ameliorates secondary influenza A virus disease
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
On one side: scientists engineering a nasal COVID vaccine that blocks Omicron transmission and boosts mucosal immunity
On the other: people still yelling “just a cold.”
Follow for science > vibes
#COVID19 #MucosalImmunity #VaccinesWork #PublicHealth #NextGenVaccines #MedSky
On the other: people still yelling “just a cold.”
Follow for science > vibes
#COVID19 #MucosalImmunity #VaccinesWork #PublicHealth #NextGenVaccines #MedSky
Intranasal vaccine combining adenovirus and trimeric subunit protein provides superior immunity against SARS-CoV-2 Omicron variant - Nature Biomedical Engineering
A combination of adenovirus-vectored and subunit protein intranasal vaccine enhances immune response against SARS-CoV-2 variants in animal models and humans.
www.nature.com
September 23, 2025 at 3:27 PM
On one side: scientists engineering a nasal COVID vaccine that blocks Omicron transmission and boosts mucosal immunity
On the other: people still yelling “just a cold.”
Follow for science > vibes
#COVID19 #MucosalImmunity #VaccinesWork #PublicHealth #NextGenVaccines #MedSky
On the other: people still yelling “just a cold.”
Follow for science > vibes
#COVID19 #MucosalImmunity #VaccinesWork #PublicHealth #NextGenVaccines #MedSky
#mucosalimmunity
link.springer.com/article/10.1...
www.mdpi.com/2218-273X/15...
onlinelibrary.wiley.com/doi/full/10....
pmc.ncbi.nlm.nih.gov/articles/PMC...
papers.ssrn.com/sol3/papers....
link.springer.com/article/10.1...
www.mdpi.com/2218-273X/15...
onlinelibrary.wiley.com/doi/full/10....
pmc.ncbi.nlm.nih.gov/articles/PMC...
papers.ssrn.com/sol3/papers....
Viruses and neurodegeneration: a growing concern - Journal of Translational Medicine
Neurodegenerative diseases (NDDs) cause a progressive loss of neurons. Since NDDs are multifactorial, the precise etiology varies on the basis of the type of disease and patient history. Cohort studie...
link.springer.com
May 31, 2025 at 4:13 AM
don’t elicit adequate #mucosalimmunity in the nose & mouth #SARSCoV2 ’s entry points into the body. Once 🦠 slips past those entry points, systemic immunity generated by #COVID19 💉 & previous infections protects against severe disease. @jama.com
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Why COVID-19 Vaccines Don’t Stop Transmission
This Medial News article discusses recent research showing that current COVID-19 vaccines fail to elicit enough of a mucosal immune response to prevent infection.
jamanetwork.com
December 20, 2024 at 5:34 PM
don’t elicit adequate #mucosalimmunity in the nose & mouth #SARSCoV2 ’s entry points into the body. Once 🦠 slips past those entry points, systemic immunity generated by #COVID19 💉 & previous infections protects against severe disease. @jama.com
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
These findings highlight the potential role of boosters or alternative strategies to sustain #mucosalimmunity in Cancer patients with on going Cancer therapy . cancer patients who received dual-dose BNT162b2 vaccination
June 28, 2025 at 5:53 AM
These findings highlight the potential role of boosters or alternative strategies to sustain #mucosalimmunity in Cancer patients with on going Cancer therapy . cancer patients who received dual-dose BNT162b2 vaccination
Last week, our lab was invited to talk at @keystonesymposia.bsky.social, where we talked about FMT & IBD and investigations on triggers towards healing. #gutmicrobiome #mucosalimmunity #fmt #ibd We would like to thank the organizers for a great meeting. Speaker: @patrickschimmel.bsky.social
February 24, 2025 at 1:26 PM
Last week, our lab was invited to talk at @keystonesymposia.bsky.social, where we talked about FMT & IBD and investigations on triggers towards healing. #gutmicrobiome #mucosalimmunity #fmt #ibd We would like to thank the organizers for a great meeting. Speaker: @patrickschimmel.bsky.social
#MedSky #IDSky #Mucosalimmunity #Tcells are crucial in preventing persistent #SARSCoV2 infection in the nasal cavity
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment
CD4+ and CD8+ T cells protect against SARS-CoV-2 viral persistence within the upper respiratory tract.
www.science.org
August 24, 2024 at 10:52 AM
#MedSky #IDSky #Mucosalimmunity #Tcells are crucial in preventing persistent #SARSCoV2 infection in the nasal cavity
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
#MedSky🧪#IDSky #Immunosky #Pulichealth There is reason why you are still wearing 😷 when you had already vaccinated . Ideally, #COVID19vaccines protect against not only severe #COVID but also infection to limit 🦠 circulation. Achieving this goal requires the induction of #mucosalimmunity through 💉
October 24, 2024 at 5:52 AM
#MedSky🧪#IDSky #Immunosky #Pulichealth There is reason why you are still wearing 😷 when you had already vaccinated . Ideally, #COVID19vaccines protect against not only severe #COVID but also infection to limit 🦠 circulation. Achieving this goal requires the induction of #mucosalimmunity through 💉
#Medsky🧪 #IDsky #virosky #immunosky #mucosalimmunity #publicheath Recent studies on mucosal #COVID vaccines have shown that they induce rapid, but often transient, IgA responses in respiratory secretions,
October 20, 2025 at 5:12 AM
#Medsky🧪 #IDsky #virosky #immunosky #mucosalimmunity #publicheath Recent studies on mucosal #COVID vaccines have shown that they induce rapid, but often transient, IgA responses in respiratory secretions,
MedSky🧪 #IDSky #viralimmunology #immunology #Mucosalimmunity Understanding mucosal #antibody responses from #SARSCoV2 infection and/or #COVID19vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants.
October 6, 2023 at 9:18 PM
MedSky🧪 #IDSky #viralimmunology #immunology #Mucosalimmunity Understanding mucosal #antibody responses from #SARSCoV2 infection and/or #COVID19vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants.
#MedSky🧪#IDSky #Microbiology This study provides evidence regarding the critical role played by the degradative capabilities of the #gutmicrobiome in specific aspects of the #mucosalimmunity and intestinal barrier system.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Microbial hoolIgAn dismantles gut defenses
Immunoglobulin degradation by a gut bacterium causes immunodeficiency in mice
www.science.org
September 27, 2024 at 4:56 PM
#MedSky🧪#IDSky #Microbiology This study provides evidence regarding the critical role played by the degradative capabilities of the #gutmicrobiome in specific aspects of the #mucosalimmunity and intestinal barrier system.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
#Medsky🧪 #IDsky #immunosky #publichealth Challenges & Considerations for Long-Term #MucosalImmunity from mucosal viral infections elicit long-lived IgA responses through type 1 follicular helper T cells, particularly in the context of #COVID19vaccination
#Medsky🧪 #IDsky #immunosky #pedsky #mucosalimmunity #virosky #publichealth Mucosal viral infections elicit long-lived IgA responses through mechanisms that critically depend on type 1 follicular helper T (Tfh1) cells, with site-specific requirements for B cell MHC class II & IFNγ signaling.
December 2, 2025 at 8:56 AM
#Medsky🧪 #IDsky #immunosky #publichealth Challenges & Considerations for Long-Term #MucosalImmunity from mucosal viral infections elicit long-lived IgA responses through type 1 follicular helper T cells, particularly in the context of #COVID19vaccination
#MedSky🧪 #IDSky #Immunosky #Publichealth #Publichealth #Mucosalimmunity #Autoantibodies targeting interferon-α (#IFNα) have been found in the circulation of those with severe #COVID19 and are considered a bad sign for disease progression.
November 7, 2024 at 9:29 AM
#MedSky🧪 #IDSky #Immunosky #Publichealth #Publichealth #Mucosalimmunity #Autoantibodies targeting interferon-α (#IFNα) have been found in the circulation of those with severe #COVID19 and are considered a bad sign for disease progression.
University of North Carolina is hiring:
Post-Doc Research Associate in Sharma Lab
#postdoc #mucosalimmunity #inflammatoryboweldiseases
Post-Doc Research Associate in Sharma Lab
#postdoc #mucosalimmunity #inflammatoryboweldiseases
September 10, 2026 at 3:03 AM
University of North Carolina is hiring:
Post-Doc Research Associate in Sharma Lab
#postdoc #mucosalimmunity #inflammatoryboweldiseases
Post-Doc Research Associate in Sharma Lab
#postdoc #mucosalimmunity #inflammatoryboweldiseases
#Medsky🧪 #immunosky #publichealth @cp-immunity.bsky.social
The study maps out a newly discovered diet-microbe-immune axis, demonstrating how eating soy during early life reshapes specific #gutbacteria to trigger targeted #mucosalimmunity and protect against infection www.cell.com/immunity/ful...
The study maps out a newly discovered diet-microbe-immune axis, demonstrating how eating soy during early life reshapes specific #gutbacteria to trigger targeted #mucosalimmunity and protect against infection www.cell.com/immunity/ful...
Dietary soy shapes the microbiome to induce commensal-specific T follicular helper cells and IgA production
Diet impacts gut microbes and, subsequently, host immunity, but our understanding
of the mechanisms driving this axis remains incomplete. Hattori-Muroi, Maruta, Takahashi,
et al. show that dietary soy...
www.cell.com
May 20, 2026 at 9:14 AM
#Medsky🧪 #immunosky #publichealth @cp-immunity.bsky.social
The study maps out a newly discovered diet-microbe-immune axis, demonstrating how eating soy during early life reshapes specific #gutbacteria to trigger targeted #mucosalimmunity and protect against infection www.cell.com/immunity/ful...
The study maps out a newly discovered diet-microbe-immune axis, demonstrating how eating soy during early life reshapes specific #gutbacteria to trigger targeted #mucosalimmunity and protect against infection www.cell.com/immunity/ful...
#Medsky🧪 #IDsky #immunosky #oncosky #publichealth #Immunoglobulin (Ig) A antibodies are involved in #mucosalimmunity and eliminate pathogens immediately at the point of entry.
July 3, 2025 at 1:15 PM
#Medsky🧪 #IDsky #immunosky #oncosky #publichealth #Immunoglobulin (Ig) A antibodies are involved in #mucosalimmunity and eliminate pathogens immediately at the point of entry.
Studies indicate that IgA subtype dynamics differ between the upper (nasal) and lower (sputum) respiratory tracts, highlighting the complexity of #mucosalimmunity
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
October 20, 2025 at 5:46 AM
Studies indicate that IgA subtype dynamics differ between the upper (nasal) and lower (sputum) respiratory tracts, highlighting the complexity of #mucosalimmunity
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
If both systemic and gut mucosal protection is desired, vaccines might need to target tonsils (for systemic immunity) as well as gut-associated lymphoid tissue (GALT) for #mucosalimmunity
July 29, 2026 at 11:53 AM
If both systemic and gut mucosal protection is desired, vaccines might need to target tonsils (for systemic immunity) as well as gut-associated lymphoid tissue (GALT) for #mucosalimmunity
This review highlights respiratory #MucosalImmunity as a frontline defense integrating barrier protection and immune memory, and advances #IntranasalVaccine strategies and inhalable therapies to enhance protection against #RespiratoryPathogens.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
April 28, 2026 at 1:30 PM
This review highlights respiratory #MucosalImmunity as a frontline defense integrating barrier protection and immune memory, and advances #IntranasalVaccine strategies and inhalable therapies to enhance protection against #RespiratoryPathogens.
#OpenAccess: doi.org/10.1016/j.ge...
#OpenAccess: doi.org/10.1016/j.ge...
NanoSTING‑SN: Houston’s intranasal pan‑coronavirus vaccine aims for sterilizing immunity + no transmission.
Strong animal data. Human trials pending funding.
This could be the endgame for COVID spread.
🔗 www.uh.edu/news-events/... #NextGenVaccines #MucosalImmunity
Strong animal data. Human trials pending funding.
This could be the endgame for COVID spread.
🔗 www.uh.edu/news-events/... #NextGenVaccines #MucosalImmunity
University of Houston Researchers Create New Treatment and Vaccine for Flu and Various Coronaviruses
Two new nasal sprays to fight coronavirus and flu developed @UHouston: one, a vaccine and one an immune activator.
www.uh.edu
September 3, 2025 at 5:20 PM
NanoSTING‑SN: Houston’s intranasal pan‑coronavirus vaccine aims for sterilizing immunity + no transmission.
Strong animal data. Human trials pending funding.
This could be the endgame for COVID spread.
🔗 www.uh.edu/news-events/... #NextGenVaccines #MucosalImmunity
Strong animal data. Human trials pending funding.
This could be the endgame for COVID spread.
🔗 www.uh.edu/news-events/... #NextGenVaccines #MucosalImmunity