#NoncodingGenome
#DarkGenome #NoncodingGenome fanatics - this one is for you. 👇

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#genomics
#bioinformatics
"Dark TFs": new manuscript mapped 166 uncharacterized human transcription factors, finding half bind genomic "dark matter," often closed chromatin rich in transposable elements.
www.biorxiv.org/content/10.1...
November 20, 2024 at 11:20 AM
Update of the FANTOM web resource: enhancement for studying noncoding genomes. #Fantom #NoncodingGenome #NAR 🧬
academic.oup.com/nar/advance-...
Update of the FANTOM web resource: enhancement for studying noncoding genomes
Abstract. The FANTOM web resource (https://fantom.gsc.riken.jp/) has been a unique resource for studying mammalian genomes, which is built on the research
academic.oup.com
December 8, 2024 at 4:24 PM
Registration is OPEN for the Gordon Research Conference on #Microproteins! Scholarships are available.

Get involved now while spaces are still available.
You won't want to miss this!

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🧬 💻
🔎 microproteins
#darkgenome
#NoncodingGenome
#Cancer
#Proteomics
#sORFs
#Ribose

www.grc.org/decoding-mic...
2025 Decoding Microproteins Across Evolution and Disease Conference GRC
The 2025 Gordon Research Conference on Decoding Microproteins Across Evolution and Disease will be held in Castelldefels, Barcelona Spain. Apply today to reserve your spot.
www.grc.org
November 29, 2024 at 6:35 PM
This is the result of a truly multidisciplinary team 🧑‍🤝‍🧑🧑‍🤝‍🧑, led by @gp83.bsky.social , @dalyaf.bsky.social and @martinfranke.bsky.social and joined by @radaiglesiaslab.bsky.social and myself for this new chapter.
#GeneticDiagnostics #NonCodingGenome #RareDisease
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July 10, 2025 at 10:11 PM
An overview on the role of the #NonCodingGenome in #GeneRegulation, its implications for understanding the #pathogenesis of complex diseases, and its potential in developing targeted therapeutic interventions. #NextGenSequencing #Genomics #medsky @nihfellowsunited.bsky.social

buff.ly/XMNmXru
May 6, 2025 at 5:02 PM
DUX4, the rockstar of embryonic genome activation?

ijdb.ehu.eus/article/2302...

by Sonja Nykänen & Sanna Vuoristo

🔑 Double Homeobox 4 (DUX4), embryo development, embryonic genome activation #GenomeActivation, gene regulation #GeneRegulation, non-coding genome #NonCodingGenome
January 17, 2025 at 2:21 PM
Cat-cat interactions are mostly dominated by pheromones and not meows.

This is really fascinating because of the genomics for all #darkgenome, #noncodinggenome, #denovogene folks.

Cats rapidly evolved CES7 as a urinary pheromone for cat-cat communication.

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pubmed.ncbi.nlm.nih.gov/20966115/
Accelerated evolution of CES7, a gene encoding a novel major urinary protein in the cat family - PubMed
Cauxin is a novel urinary protein recently identified in the domestic cat that regulates the excretion of felinine, a pheromone precursor involved in sociochemical communication and territorial markin...
pubmed.ncbi.nlm.nih.gov
November 27, 2024 at 7:14 PM