🚀 Big news! We've just published the official guidelines for submitting affinity proteomics data to PRIDE @pride-ebi.bsky.social (supported technologies Olink & SomaScan)!
Get ahead of the curve—check them out & start your submissions! 👇
🔗 github.com/PRIDE-Archiv...
#Proteomics #Olink #SomaScan
Get ahead of the curve—check them out & start your submissions! 👇
🔗 github.com/PRIDE-Archiv...
#Proteomics #Olink #SomaScan
github.com
March 28, 2025 at 7:20 AM
🚀 Big news! We've just published the official guidelines for submitting affinity proteomics data to PRIDE @pride-ebi.bsky.social (supported technologies Olink & SomaScan)!
Get ahead of the curve—check them out & start your submissions! 👇
🔗 github.com/PRIDE-Archiv...
#Proteomics #Olink #SomaScan
Get ahead of the curve—check them out & start your submissions! 👇
🔗 github.com/PRIDE-Archiv...
#Proteomics #Olink #SomaScan
tl;dr it's Olink. I know that's what you wanted to ask 🤣😜
Atlas of the plasma proteome in health and disease in 53,026 adults. #Cell #medBsky #SciBsky #scisky #proteome
These results provide an open-access comprehensive proteome-phenome resource (proteome-phenome-atlas.com).
Open Access
www.cell.com/cell/fulltex...
These results provide an open-access comprehensive proteome-phenome resource (proteome-phenome-atlas.com).
Open Access
www.cell.com/cell/fulltex...
November 26, 2024 at 1:28 AM
tl;dr it's Olink. I know that's what you wanted to ask 🤣😜
A paper addressing discrepancies between Olink and SOMAscan. Most important factor explaining the (non)correlation is the % of LOD samples in Olink:
Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults
www.nature.com/articles/s41...
Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults
www.nature.com/articles/s41...
March 9, 2025 at 10:41 AM
A paper addressing discrepancies between Olink and SOMAscan. Most important factor explaining the (non)correlation is the % of LOD samples in Olink:
Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults
www.nature.com/articles/s41...
Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults
www.nature.com/articles/s41...
The HBCD Study Data Release 2.1 is here 👇🏾
3,500+ children followed from pregnancy through early childhood: MRI, dMRI, resting-state fMRI, EEG, biospecimens incl. genetics, wearables, and rich behavioral + environmental data.
New in 2.1: Olink inflammation markers + the ERICA assessment.
3,500+ children followed from pregnancy through early childhood: MRI, dMRI, resting-state fMRI, EEG, biospecimens incl. genetics, wearables, and rich behavioral + environmental data.
New in 2.1: Olink inflammation markers + the ERICA assessment.
August 15, 2026 at 3:03 PM
The HBCD Study Data Release 2.1 is here 👇🏾
3,500+ children followed from pregnancy through early childhood: MRI, dMRI, resting-state fMRI, EEG, biospecimens incl. genetics, wearables, and rich behavioral + environmental data.
New in 2.1: Olink inflammation markers + the ERICA assessment.
3,500+ children followed from pregnancy through early childhood: MRI, dMRI, resting-state fMRI, EEG, biospecimens incl. genetics, wearables, and rich behavioral + environmental data.
New in 2.1: Olink inflammation markers + the ERICA assessment.
I’d bet 100 ProtCoins it’s Olink.
July 1, 2026 at 12:56 AM
I’d bet 100 ProtCoins it’s Olink.
Another of the plasma proteome deluge. Somascan ans olink having 0.29 correlation
Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults www.nature.com/artic...
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#proteomics #prot-paper
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#proteomics #prot-paper
February 23, 2025 at 11:55 AM
Another of the plasma proteome deluge. Somascan ans olink having 0.29 correlation
Aβ42), pTau-181, NfL und saures Gliafaserprotein (GFAP) gemessen. Darüber hinaus wurde in der Studie eine proteomische Analyse von 1.468 Proteinen mit der Olink Explore-Plattform durchgeführt, die ein umfassenderes Verständnis der Auswirkungen von SARS-CoV-2 auf die
bsky.app/profile/ralf...
bsky.app/profile/ralf...
SARS-CoV-2-Infektion als Ursache von Neurodegeneration
1. Eine #SARSCoV2-Infektion sollte als Risikofaktor für die Alzheimer-Krankheit betrachtet werden, auch wenn die Unterscheidung zwischen Verursachung und Krankheitsbeschleunigung nicht klar ist. 🧵
#Alzheimers #LongCovid
1. Eine #SARSCoV2-Infektion sollte als Risikofaktor für die Alzheimer-Krankheit betrachtet werden, auch wenn die Unterscheidung zwischen Verursachung und Krankheitsbeschleunigung nicht klar ist. 🧵
#Alzheimers #LongCovid
February 3, 2025 at 11:33 PM
Aβ42), pTau-181, NfL und saures Gliafaserprotein (GFAP) gemessen. Darüber hinaus wurde in der Studie eine proteomische Analyse von 1.468 Proteinen mit der Olink Explore-Plattform durchgeführt, die ein umfassenderes Verständnis der Auswirkungen von SARS-CoV-2 auf die
bsky.app/profile/ralf...
bsky.app/profile/ralf...
Our latest Study just went online:
Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Comparative Analysis Between Olink‐PEA and Alamar‐NULISA Proteomic Technologies Applied to a Critically Ill COVID‐19 Cohort
We aim to verify and validate low-abundant plasma proteins from severe COVID-19 cases and controls through a comparative analysis between Olink and Alamar performances. Eighty-three severe cases and ....
analyticalsciencejournals.onlinelibrary.wiley.com
February 11, 2025 at 12:15 PM
Our latest Study just went online:
Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Comparative Analysis Between Olink-PEA and Alamar-NULISA Proteomic Technologies Applied to a Critically Ill COVID-19 Cohort
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Interested in joint multiomics data?
Metabolon, Biocrates, Lipidyzer, Chenomx, SOMAscan, Olink, Nightingale, Genos, Exiqon and Illumina genomics (OmniArray, HumanMethylation, RNAseq)
Check out our COMICS server
littleswissriver.shinyapps.io/generate_net...
and BLOG
www.metabolomix.com/comics/
Metabolon, Biocrates, Lipidyzer, Chenomx, SOMAscan, Olink, Nightingale, Genos, Exiqon and Illumina genomics (OmniArray, HumanMethylation, RNAseq)
Check out our COMICS server
littleswissriver.shinyapps.io/generate_net...
and BLOG
www.metabolomix.com/comics/
March 16, 2025 at 1:27 PM
Interested in joint multiomics data?
Metabolon, Biocrates, Lipidyzer, Chenomx, SOMAscan, Olink, Nightingale, Genos, Exiqon and Illumina genomics (OmniArray, HumanMethylation, RNAseq)
Check out our COMICS server
littleswissriver.shinyapps.io/generate_net...
and BLOG
www.metabolomix.com/comics/
Metabolon, Biocrates, Lipidyzer, Chenomx, SOMAscan, Olink, Nightingale, Genos, Exiqon and Illumina genomics (OmniArray, HumanMethylation, RNAseq)
Check out our COMICS server
littleswissriver.shinyapps.io/generate_net...
and BLOG
www.metabolomix.com/comics/
That's a wrap on the Olink Summit and Bioinformatics Day in Boston! 🧬
Need support with your Olink data analysis? Omics Playground can help 👉https://bigomics.ch/contact-us/
#olinkhorizons2026 #olink #proteomics #massspectrometry #bioinformatics #omicsplayground
Need support with your Olink data analysis? Omics Playground can help 👉https://bigomics.ch/contact-us/
#olinkhorizons2026 #olink #proteomics #massspectrometry #bioinformatics #omicsplayground
September 24, 2026 at 11:56 AM
That's a wrap on the Olink Summit and Bioinformatics Day in Boston! 🧬
Need support with your Olink data analysis? Omics Playground can help 👉https://bigomics.ch/contact-us/
#olinkhorizons2026 #olink #proteomics #massspectrometry #bioinformatics #omicsplayground
Need support with your Olink data analysis? Omics Playground can help 👉https://bigomics.ch/contact-us/
#olinkhorizons2026 #olink #proteomics #massspectrometry #bioinformatics #omicsplayground
Profiling the proteome has turned out to be a challenging task.
Available platforms offer increasingly broader coverage, but often yield different results for the same proteins.
This preprint compares quantifications of mass spectrometry & Olink in the same samples👇
Available platforms offer increasingly broader coverage, but often yield different results for the same proteins.
This preprint compares quantifications of mass spectrometry & Olink in the same samples👇
May 10, 2025 at 4:05 PM
Profiling the proteome has turned out to be a challenging task.
Available platforms offer increasingly broader coverage, but often yield different results for the same proteins.
This preprint compares quantifications of mass spectrometry & Olink in the same samples👇
Available platforms offer increasingly broader coverage, but often yield different results for the same proteins.
This preprint compares quantifications of mass spectrometry & Olink in the same samples👇
Researchers in London, Ont., say a NEW laboratory equipped with cutting-edge technology will help them detect childhood diseases earlier and develop more personalized treatments for young patients. #Canada
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
New London lab aims to detect childhood diseases before symptoms appear | CBC News
Researchers at Children's Health Research Institute say Canada's first pediatric Olink laboratory will help diagnose childhood diseases earlier and develop more personalized treatments using advanced ...
www.cbc.ca
August 20, 2026 at 1:59 PM
Researchers in London, Ont., say a NEW laboratory equipped with cutting-edge technology will help them detect childhood diseases earlier and develop more personalized treatments for young patients. #Canada
www.cbc.ca/news/canada/...
www.cbc.ca/news/canada/...
In case you missed my #genetic association study with #proteomics using #ratios between protein levels from #OLINK in #UKBIOBANK - it came out earlier this year in #Cell #Genomics :
doi.org/10.1016/j.xg...
doi.org/10.1016/j.xg...
December 11, 2024 at 1:41 PM
In case you missed my #genetic association study with #proteomics using #ratios between protein levels from #OLINK in #UKBIOBANK - it came out earlier this year in #Cell #Genomics :
doi.org/10.1016/j.xg...
doi.org/10.1016/j.xg...
Finally, an experienced MS group performed a proper comparison of MS plasma proteomics vs. Olink! Kudos to the Coon lab! Cannot wait to read all the details!
Nice review of plasma proteomics methods by Josh Coon and his group . However the perchloric acid treatment of plasma will lead to the formation of cysteic acid and methionine sulphone which is not mentioned for the DIA search. .https://www.biorxiv.org/content/10.1101/2025.01.08.632035v1
A Technical Evaluation of Plasma Proteomics Technologies
Plasma proteomic technologies are rapidly evolving and of critical importance to the field of biomedical research. Here we report a technical evaluation of six notable plasma proteomic technologies - ...
www.biorxiv.org
January 14, 2025 at 11:09 AM
Finally, an experienced MS group performed a proper comparison of MS plasma proteomics vs. Olink! Kudos to the Coon lab! Cannot wait to read all the details!
Wow - that's really impressive!
UKB-PPP aims to analyze more than 5,400 proteins from 600,000 samples using the #OLINK platform @ukbiobank.bsky.social
newsroom.thermofisher.com/newsroom/pre...
UKB-PPP aims to analyze more than 5,400 proteins from 600,000 samples using the #OLINK platform @ukbiobank.bsky.social
newsroom.thermofisher.com/newsroom/pre...
Thermo Fisher Scientific’s Olink Platform Selected for World’s Largest Human Proteome Study
UK Biobank Pharma Proteomics Project aims to create a comprehensive map of disease-associated protein levels in the human body to advance biomarker discovery Thermo Fisher Scientific Inc. (NYSE: TMO),...
newsroom.thermofisher.com
January 10, 2025 at 12:20 PM
Wow - that's really impressive!
UKB-PPP aims to analyze more than 5,400 proteins from 600,000 samples using the #OLINK platform @ukbiobank.bsky.social
newsroom.thermofisher.com/newsroom/pre...
UKB-PPP aims to analyze more than 5,400 proteins from 600,000 samples using the #OLINK platform @ukbiobank.bsky.social
newsroom.thermofisher.com/newsroom/pre...
Sleep, Time & Exercise Matter
Cardiovascular biomarkers shift with sleep loss, time of day, and activity – affecting how we assess heart risk.
🔗 biomarkerres.biomedcentral.com/articles/10....
#Sleep #HeartHealth #Biomarkers #SciComm 🧪
Cardiovascular biomarkers shift with sleep loss, time of day, and activity – affecting how we assess heart risk.
🔗 biomarkerres.biomedcentral.com/articles/10....
#Sleep #HeartHealth #Biomarkers #SciComm 🧪
The overlooked trio: sleep duration, sampling time and physical exercise alter levels of olink-assessed blood biomarkers of cardiovascular risk - Biomarker Research
Biomarker profiling from biofluids such as blood are widely measured in clinical research, using for example Olink proteomics panels. One such research focus area is cardiovascular disease (CVD), for ...
biomarkerres.biomedcentral.com
May 25, 2025 at 10:31 AM
Sleep, Time & Exercise Matter
Cardiovascular biomarkers shift with sleep loss, time of day, and activity – affecting how we assess heart risk.
🔗 biomarkerres.biomedcentral.com/articles/10....
#Sleep #HeartHealth #Biomarkers #SciComm 🧪
Cardiovascular biomarkers shift with sleep loss, time of day, and activity – affecting how we assess heart risk.
🔗 biomarkerres.biomedcentral.com/articles/10....
#Sleep #HeartHealth #Biomarkers #SciComm 🧪
Proteomics (not Nirvana, @benneely.com) unplugged: olink.com/products/oli.... While I still ❤️ mass spectrometry, I understand why this techology is becoming so popular among biologists.
Olink Reveal — Olink®
olink.com
January 27, 2025 at 2:25 PM
Proteomics (not Nirvana, @benneely.com) unplugged: olink.com/products/oli.... While I still ❤️ mass spectrometry, I understand why this techology is becoming so popular among biologists.
I spend a bit of time talking to folk with plasma cohorts about MS vs affinity approaches for discovery. Thought it was worth a thread.
Most love the marketing. 5,000 proteins? 10,000 proteins? OLink was used in UK Biobank? Wow, mass spec is sooooo last year. Except life is not that simple.
Most love the marketing. 5,000 proteins? 10,000 proteins? OLink was used in UK Biobank? Wow, mass spec is sooooo last year. Except life is not that simple.
Somalogic, Olink, and Alamar are casting doubt on each other’s data, proudly calling out lack of correlation.
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
November 21, 2024 at 9:30 AM
I spend a bit of time talking to folk with plasma cohorts about MS vs affinity approaches for discovery. Thought it was worth a thread.
Most love the marketing. 5,000 proteins? 10,000 proteins? OLink was used in UK Biobank? Wow, mass spec is sooooo last year. Except life is not that simple.
Most love the marketing. 5,000 proteins? 10,000 proteins? OLink was used in UK Biobank? Wow, mass spec is sooooo last year. Except life is not that simple.
I'm delighted to announce that the Pharma Proteomics Project will commence full-scale proteomic profiling of the UK Biobank in 2025. We have selected the Olink Proteomics Explore HT platform and Ultima Genomics UG 100 sequencers for this unprecedented study.
www.ukbiobank.ac.uk/learn-more-a...
www.ukbiobank.ac.uk/learn-more-a...
Launch of world’s most significant protein study set to usher in new understanding for medicine
www.ukbiobank.ac.uk
January 10, 2025 at 8:18 AM
I'm delighted to announce that the Pharma Proteomics Project will commence full-scale proteomic profiling of the UK Biobank in 2025. We have selected the Olink Proteomics Explore HT platform and Ultima Genomics UG 100 sequencers for this unprecedented study.
www.ukbiobank.ac.uk/learn-more-a...
www.ukbiobank.ac.uk/learn-more-a...
Here is a more in-depth explanation of the science that will take place in UK Biobank using Next-Gen Proteomics technology Olink (now part of Thermo) and Ultima Genomics.
I'm delighted to announce that the Pharma Proteomics Project will commence full-scale proteomic profiling of the UK Biobank in 2025. We have selected the Olink Proteomics Explore HT platform and Ultima Genomics UG 100 sequencers for this unprecedented study.
www.ukbiobank.ac.uk/learn-more-a...
www.ukbiobank.ac.uk/learn-more-a...
Launch of world’s most significant protein study set to usher in new understanding for medicine
www.ukbiobank.ac.uk
January 10, 2025 at 8:23 AM
Here is a more in-depth explanation of the science that will take place in UK Biobank using Next-Gen Proteomics technology Olink (now part of Thermo) and Ultima Genomics.
Somalogic, Olink, and Alamar are casting doubt on each other’s data, proudly calling out lack of correlation.
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
November 20, 2024 at 10:42 PM
Somalogic, Olink, and Alamar are casting doubt on each other’s data, proudly calling out lack of correlation.
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
I know why they do this but in the long run as it casts doubt on affinity approaches as a whole.
We will think lots of data is generated that is trash and won’t know which
We are risking immune damage by continuing to be exposed to Covid reinfections. www.nature.com/articles/s41...
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2 - Nature Immunology
Roan et al. use Olink and single‐cell RNA sequencing (scRNA-seq) to show a dysregulated crosstalk between the cellular and humoral immune responses in individuals with long COVID 8 months postinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
www.nature.com
September 25, 2025 at 9:56 AM
We are risking immune damage by continuing to be exposed to Covid reinfections. www.nature.com/articles/s41...
A beautiful example illustrating a difference between plasma protein analysis by different technologies.
Peptides from some proteoforms correlate better to epitope-based measurements (Olink) than others.
The measurements differ because they reflect different proteoforms !
Peptides from some proteoforms correlate better to epitope-based measurements (Olink) than others.
The measurements differ because they reflect different proteoforms !
November 8, 2025 at 2:03 PM
A beautiful example illustrating a difference between plasma protein analysis by different technologies.
Peptides from some proteoforms correlate better to epitope-based measurements (Olink) than others.
The measurements differ because they reflect different proteoforms !
Peptides from some proteoforms correlate better to epitope-based measurements (Olink) than others.
The measurements differ because they reflect different proteoforms !