mpreg / Destiny AU p53
Their love… 🥹
Their love… 🥹
May 20, 2026 at 5:05 PM
mpreg / Destiny AU p53
Their love… 🥹
Their love… 🥹
hearthside is officially finished! come visit us at:
dyn - kraken - emp - w29 - p53
dyn - kraken - emp - w29 - p53
October 12, 2025 at 7:06 PM
hearthside is officially finished! come visit us at:
dyn - kraken - emp - w29 - p53
dyn - kraken - emp - w29 - p53
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/4i9qZ7J
🧪 🩺 https://buff.ly/4i9qZ7J
February 22, 2025 at 12:02 AM
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/4i9qZ7J
🧪 🩺 https://buff.ly/4i9qZ7J
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/3EJ8Krw
🧪 🩺 https://buff.ly/3EJ8Krw
February 21, 2025 at 12:02 AM
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/3EJ8Krw
🧪 🩺 https://buff.ly/3EJ8Krw
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/3ES0gOG
🧪 🩺 https://buff.ly/3ES0gOG
February 23, 2025 at 1:07 PM
The protein #p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells. A #biology researcher explains:
🧪 🩺 https://buff.ly/3ES0gOG
🧪 🩺 https://buff.ly/3ES0gOG
Selective metabolic regulations by p53 mutant variants in pancreatic cancer 🧪
Congrats @ivanoamelio.bsky.social & team
jeccr.biomedcentral.com/articles/10....
Congrats @ivanoamelio.bsky.social & team
jeccr.biomedcentral.com/articles/10....
Selective metabolic regulations by p53 mutant variants in pancreatic cancer - Journal of Experimental & Clinical Cancer Research
Background Approximately half of all human cancers harbour mutations in the p53 gene, leading to the generation of neomorphic p53 mutant proteins. These mutants can exert gain-of-function (GOF) effect...
jeccr.biomedcentral.com
December 1, 2024 at 6:34 AM
Selective metabolic regulations by p53 mutant variants in pancreatic cancer 🧪
Congrats @ivanoamelio.bsky.social & team
jeccr.biomedcentral.com/articles/10....
Congrats @ivanoamelio.bsky.social & team
jeccr.biomedcentral.com/articles/10....
El talón de Aquiles del cáncer La proteína p53, conocida como "guardiana del genoma", acumula mutaciones en aproximadamente el 50% de todos los cánceres .
CRISPR-Cas12a2 destruye células cancerosas intratables atacando el ARN de p53 mutante con precisión de un nucleótido - Sinaptica
El talón de Aquiles del cáncer
La proteína p53, conocida como "guardiana del genoma", acumula mutaciones en aproximadamente el 50% de todos los cánceres. En los
sinapti.ca
June 8, 2026 at 3:16 PM
El talón de Aquiles del cáncer La proteína p53, conocida como "guardiana del genoma", acumula mutaciones en aproximadamente el 50% de todos los cánceres .
THE ENORMITIES KNOWN TO EXIST
P53
P53
July 2, 2026 at 2:24 AM
THE ENORMITIES KNOWN TO EXIST
P53
P53
Although tricky to target, #ProstateCancer cells that lack p53 still depend on the integrated stress response and can be killed with inhibitors of the enzyme GCN2 that disrupt purine synthesis.
Read more in #ScienceSignaling: scim.ag/3D6Lyme
Read more in #ScienceSignaling: scim.ag/3D6Lyme
Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
Targeting a cell stress response is synthetic lethal with loss of p53 in prostate cancer cells.
scim.ag
December 11, 2024 at 8:01 PM
Although tricky to target, #ProstateCancer cells that lack p53 still depend on the integrated stress response and can be killed with inhibitors of the enzyme GCN2 that disrupt purine synthesis.
Read more in #ScienceSignaling: scim.ag/3D6Lyme
Read more in #ScienceSignaling: scim.ag/3D6Lyme
P53 is Jack Wilenchik
October 2, 2024 at 10:03 PM
P53 is Jack Wilenchik
🔞⛓️🌧️ a/b/o wriolette p53/?
i just made up whatever scent glands might look like lmao
poipiku.com/7336637/1153...
i just made up whatever scent glands might look like lmao
poipiku.com/7336637/1153...
January 25, 2026 at 6:37 PM
🔞⛓️🌧️ a/b/o wriolette p53/?
i just made up whatever scent glands might look like lmao
poipiku.com/7336637/1153...
i just made up whatever scent glands might look like lmao
poipiku.com/7336637/1153...
The protein p53, known as the "guardian of the genome," plays a crucial role in preventing #cancer. When it malfunctions, tumors can form. Scientists are developing drugs to restore or mimic p53's function in cancer cells.
A #biology researcher explains:
A #biology researcher explains:
p53 is both your genome’s guardian and weakness against cancer – scientists are trying to repair or replace it when it goes awry
The gene that codes for p53 is the most frequently mutated in cancer. Researchers are targeting different parts of its complex pathway to restore its ability to stop cancer.
buff.ly
June 3, 2025 at 11:48 AM
You ask: "Where's my flying car?"
I ask: "Where's my omnibus p53 cancer drug?"
I ask: "Where's my omnibus p53 cancer drug?"
March 29, 2026 at 6:31 PM
You ask: "Where's my flying car?"
I ask: "Where's my omnibus p53 cancer drug?"
I ask: "Where's my omnibus p53 cancer drug?"
女儿的生物课还学肿瘤抑制蛋白p53有五个域四条链，怎样跟DNA结合。这些都应该是博士生课程内容，不过会让小孩觉得分子生物学有意思。
March 13, 2025 at 7:47 PM
女儿的生物课还学肿瘤抑制蛋白p53有五个域四条链，怎样跟DNA结合。这些都应该是博士生课程内容，不过会让小孩觉得分子生物学有意思。
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.
May 17, 2026 at 5:53 PM
Surprised to discover that Thermo Fisher appears to show a fake western blot for the validation of one of their p53 antibodies. I've added a diagram to show the very similar bands. This does not appear to be one of the "published figures" but their own internal data.
Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!
May 22, 2026 at 12:07 PM
Earlier this week I posted an example of a fake western blot provided by ThermoFisher to demonstrate the validity of a p53 antibody. I considered it an amusing curiosity. In fact Thermo Fisher Scientific has systematically manipulated antibody validation data!
January 18, 2025 at 12:13 PM
August 13, 2025 at 6:01 PM
Notice how he says COVID and not covid vaccines...
Dr. Patrick Soon-Shiong warns that COVID may suppress P53—the “guardian” gene that protects against cancer.
Elephants have 8 copies of it; Humans only 1.
Full interview here: www.youtube.com/watch?v=uqxC...
Dr. Patrick Soon-Shiong warns that COVID may suppress P53—the “guardian” gene that protects against cancer.
Elephants have 8 copies of it; Humans only 1.
Full interview here: www.youtube.com/watch?v=uqxC...
November 13, 2025 at 2:16 AM
Notice how he says COVID and not covid vaccines...
Dr. Patrick Soon-Shiong warns that COVID may suppress P53—the “guardian” gene that protects against cancer.
Elephants have 8 copies of it; Humans only 1.
Full interview here: www.youtube.com/watch?v=uqxC...
Dr. Patrick Soon-Shiong warns that COVID may suppress P53—the “guardian” gene that protects against cancer.
Elephants have 8 copies of it; Humans only 1.
Full interview here: www.youtube.com/watch?v=uqxC...
Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
January 8, 2025 at 12:14 PM
Excited to share the first paper from my lab 🤩 - a great collaboration with Dani Fachinetti lab - we discover a #mechanosensitive nuclear envelope #checkpoint that arrests cells directly post chromosome mis-segregation rdcu.be/d5AC9 👇🧵 #cancer #mechanics #p53 #chromatin
November 23, 2024 at 7:18 PM
Y hasta aquí este fascinante descubrimiento científico. Espero que te haya parecido tan interesante como a mí 😊 Para saber más sobre este estudio, puedes leer directamente el artículo científico aquí 👇🏽 #FinDelHilo
academic.oup.com/mbe/article/...
academic.oup.com/mbe/article/...
The Elephant Evolved p53 Isoforms that Escape MDM2-Mediated Repression and Cancer
Abstract. The p53 tumor suppressor is a transcription factor with roles in cell development, apoptosis, oncogenesis, aging, and homeostasis in response to
academic.oup.com
August 23, 2026 at 10:22 AM
Y hasta aquí este fascinante descubrimiento científico. Espero que te haya parecido tan interesante como a mí 😊 Para saber más sobre este estudio, puedes leer directamente el artículo científico aquí 👇🏽 #FinDelHilo
academic.oup.com/mbe/article/...
academic.oup.com/mbe/article/...
