A chemist at a university in Pakistan found a surprise when he opened an alert from ResearchGate on a newly published paper on a topic related to his own work.  When Muhammad Kashif, a chemist…

Glioblastoma multiforme (GBM) is the most malignant primary brain tumor of the central nervous system. Despite advances in therapy, it remains largely untreatable, in part due to the low permeability of chemotherapeutic drugs across the blood–brain barrier (BBB) which significantly compromises their effectiveness.

We present a transition metal-free approach to 2-N-substituted indenones, cyclopentenones, and 4-carbonyl oxazoles, based on the reaction of 5-acylated N-fluoroalkyl substituted 1,2,3-triazoles (prepa...