Silibinin is the major active molecule of silymarin, the mixture of flavonolignans extracted from Cirsium japonicum. It has been used for the treatment of hepatitis and inflammation-related diseases. ...

Signal transducer and activator of transcription 3 (STAT3) has a prominent role in mediating resistance to conventional chemo-/radio-therapies and modern targeted drugs. While a number of STAT3 inhibi...

Product description Lega Phyton is a supplementary feed for dogs and cats. Lega Phyton contains silymarin from the milk thistle fruit. Silymarin is a complex consisting of the flavonoids silibinin, silidianin and silycristin. These can help stabilise ribosomal protein synthesis, which can contribute to the regeneration and formation of hepatocytes. Furthermore, the cell membrane can have a supportive effect, which could prevent the penetration of hepatotoxic substances. When is Lega Phyton given? Lega Phyton can help support liver function in stressful factors or be used in the therapy of liver diseases. Please note that you should consult a veterinarian before giving whether this is a suitable product for your pet and follow the instructions of your veterinarian. Only if a veterinarian is diagnosed should a supplementary feed be administered. What does the liver do? The liver is a vital organ for survival. It is responsible for the metabolism in the body and produces bile for optimal digestion. If the liver is impaired in its function, this will affect the overall health status of your pet. Therefore, it is important to consult a veterinarian as soon as possible in case of health abnormalities. This means that a disease can be detected and treated at an early stage. How long do I have to give the Lega Phyton? The Lega Phyton should be administered twice daily, if prescribed by a veterinarian. After a continuous dose of 10 days, the dosage is halved. This is followed by a dose of 1x daily as a continuous dose. If your dog has been diagnosed with a disease, it is important to have the course of the disease checked regularly. Ingredients Composition: lactose, milk thistle seeds, lecithin, soy fibres, mixture of polydextrose, talc and medium chain triglycerides, magnesium stearate, soy protein hydrolysate. P.when('A').execute(function(A) { A.on('a:expander:toggle_description:toggle:collapse', function(data) { window.scroll(0, data.expander.$expander[0].offsetTop-100); }); }); Directions 1 tablet / 10 kg kg 2 x daily. After a period of use of 10 days, the dose can be halved, i.e. can be switched to 1 x daily dose. water for free absorption. See more

Milk thistle (Silybum marianum) contains silymarin, which is a mixture of flavonolignans, mainly silibinin (also known as silybin), as well as silycristine, silydianin, quercetin and taxifolin.[1] Sil...

Read the full paper: Silibinin Ameliorated Lipid Accumulation Through Insulin/IGF-1 signaling Pathway in HGI C. elegans

CNIO researchers have discovered that cancer perverts certain brain cells, the astrocytes, and causes them to produce a protein that works in favour of the tumour. A drug, silibinin, inhibits this pro...

CNIO researchers have discovered that cancer perverts certain brain cells, the astrocytes, and causes them to produce a protein that works in favour of the tumour. A drug, silibinin, inhibits this pro...

PubMed link

Background: Silibinin exerts hepatoprotective, anti-inflammatory and anti-fibrotic effects. Several pre-clinical studies have shown anti-tumoral activity of silibinin in breast cancer cell lines. Case...