#VirtualCell
Tahoe-100M

Single-cell transcriptomic perturbation atlas🤠

~100 M cells
~50 Cancer cell lines/spheroids (any normal cell for toxicity?)
~1100 small-molecule agents
52k cell-drug interactions
Mosaic platform

#OpenScience #VirtualCell
bioRxiv 2025
www.biorxiv.org/content/10.1...
June 28, 2025 at 7:38 PM
Zhenyu Ma, Xukai Jiang: PRAXIS-VirtualCell: A Programmable and Trustworthy Framework for Agentic Virtual Cell Experiments https://arxiv.org/abs/2609.29221 https://arxiv.org/pdf/2609.29221 https://arxiv.org/html/2609.29221
September 25, 2026 at 7:00 AM
The preprint detailing the results of the #SchmidtCenter Cancer Immunotherapy Machine Learning Competition is online!

@broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell

www.biorxiv.org/content/10.6...
May 22, 2026 at 10:43 PM
AI Model Makes Developmental Paths of Cells Traceable

An international research team, led by Prof. Fabian Theis, #HelmholtzMunich & @tum.de, has developed #RegVelo, an #AI-based model that can reconstruct developmental paths of cells.

👉 t1p.de/r6wgl

#VirtualCell
May 12, 2026 at 4:36 AM
https://academic.oup.com/nar/article/53…
January 10, 2025 at 10:40 PM
🚀 Recursion has been laying the foundation for a virtual cell from day one – including massive-scale, proprietary biological & chemical datasets, AI models & one of the industry’s most powerful supercomputers. Learn about our progress & what's next: www.recursion.com/news/since-i... #virtualcell
December 4, 2025 at 4:51 PM
Mapping the Kidney at Single-Cell Resolution 🤖

#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.

👉 t1p.de/yf554

#CellAtlas
March 5, 2026 at 9:35 AM
The emergence of the artificial intelligence virtual cell heralds a profound paradigm shift in oncology. This shift moves from traditional reductionist dissection of biological components to a generative, systems-level paradigm.
doi.org/10.59717/j.x...
#oncology #artificialintelligence #VirtualCell
March 28, 2026 at 5:36 AM
The big problem with this notion of #VirtualCell www.cell.com/cell/fulltex... is the axiom that a cell is the outcome of the interactions between the genes it harbors. Any cell biologist will tell you that this is empirically wrong. #Cells are masters of their genes not the other way around.
Virtual Cell Challenge: Toward a Turing test for the virtual cell
Virtual cells are an emerging frontier at the intersection of artificial intelligence and biology. A key goal of these cell state models is predicting cellular responses to perturbations. The Virtual ...
www.cell.com
June 26, 2025 at 9:00 PM
Biology is spatial —and so shall a foundation model be.🌍I’m excited to share OCTO-VirtualCell, our latest model and the Celleporter platform @Noetik —work I’m deeply proud of and believe is transformative for spatial biology.
report: noetik.ai/octo-vc
demo: celleporter.noetik.ai
OCTO-vc
Celleporter is a simulator of spatial biology that predicts gene expression patterns for virtual cells embedded in patient tissue samples.
noetik.ai
December 18, 2024 at 5:16 PM
This perspective outlines the transition from virtual cells toward dynamic virtual bacteria—a new framework that seeks to reconstruct prokaryotic life in silico with evolutionary and adaptive capability.
doi.org/10.59717/j.x...
#LifeSciences #VirtualCell
May 6, 2026 at 4:36 AM
🎉 Daniel Cohen, President of Valence Labs (@valenceai.bsky.social),
Recursion’s AI research engine, has been named a “Rising Leader” by Citeline. #TechBio #AI #ML #research #virtualcell

👉Read more: insights.citeline.com/in-vivo/lead...
September 5, 2025 at 1:45 PM
@theinnovation.bsky.social #webinar: Virtual Cells in Oncology: Foundations and Advances.
Speaker: Shixiang Wang, MD
Date & Time: Aug. 29, 2026 | 21:00-22:00 (Beijing Time)
VooV meeting ID: 499-230-347
Join us this Saturday!
#VirtualCell #oncology
August 27, 2026 at 2:18 AM
🔥 REGISTER NOW: Westlake Symposium on AI Proteomics & Virtual Cell!
🔗https://docs.qq.com/form/page/DTUxvaW5RSFJBeUx4
🗓️ Oct 8-9, 2025
📍 Westlake University, Hangzhou, China
📧zhuhuinan@westlake.edu.cn
Join global pioneers at the intersection of AI+Life Science! #AIProteomics #VirtualCell #AIinScience
July 3, 2025 at 12:35 PM
200+ live for our series kickoff! 🚀

Huge thanks to everyone who joined our Virtual Biology Community Meetup yesterday.

Missed it? Catch the replay: 📺 youtu.be/ptMy4yhZT8Q

#virtualbiology #decodingbiology #virtualcell #virtualizeexperiments #aiforbiology #drugdiscovery
Virtual Biology Community Meetup
YouTube video by Turbine Simulated Cell Technologies
youtu.be
January 20, 2026 at 4:28 PM
Reflecting on #virtualcell: Given that no cell is an island, what's the chance of inferring biology looking at just a single cell's transcriptome? As a recent preprint (arxiv.org/abs/2503.03485) said, "After all, we do not have healthy or diseased annotations for individual cells." #singlecell
TEDDY: A Family Of Foundation Models For Understanding Single Cell Biology
Understanding the biological mechanism of disease is critical for medicine, and in particular drug discovery. AI-powered analysis of genome-scale biological data hold great potential in this regard. T...
arxiv.org
April 18, 2025 at 11:54 AM
The Cell article highlights an ambitious research initiative leveraging #AI to decode complex human biological systems. Another great example of AI reshaping #biomedical research and enabling scientific discoveries once deemed impossible. #CellBiology #VirtualCell #AcademicSky
How to build the virtual cell with artificial intelligence: Priorities and opportunities
Advances in AI and omics enable the creation of AI virtual cells (AIVCs)—multi-scale, multimodal neural network models that simulate molecules, cells, and tissues across diverse states. This vision outlines their design and collaborative development, promising to transform biological research through high-fidelity simulations, accelerating discoveries, and fostering interdisciplinary open science collaborations.
www.cell.com
December 13, 2024 at 12:26 PM
AIDO Cell simulates a whole human cell, DNA to structure, and remembers each step. Bold claim; wet-lab proof is still pending. Read the breakdown. #AIinBiology #VirtualCell #DrugDiscovery

artificialscience.org/2026/08/ai-v...
A Nobel Laureate's AI Just Tried to Simulate a Whole Human Cell — Artificial Science
GenBio AI's AIDO Cell is a 'world model' that simulates a human cell across scales, from DNA to shape. Here's what it does, why it matters, and what still needs proving.
artificialscience.org
August 25, 2026 at 5:53 AM
The #Evidence has been growing that the #Universe is #Infinite but it may all come crashing down : Medium

‘#VirtualCell’ captures the most-basic #Process of #Life: #Bacterial #Division : Nature

#Peptides are everywhere. Here’s what you need to know: Tech Review

knowledgezone.co.in/resources/bo...
March 20, 2026 at 6:32 AM
Gene programs are the missing link for interpretable virtual cells.

This framework maps perturbations to phenotypes & paves the way for patient digital twins.

Read more: www.sciexplor.com/exo/articles...

#VirtualCell #GenePrograms #SingleCell #Genomics #SpatialOmics #EXOBeyondtheCell
June 26, 2026 at 2:38 AM
🎉New Perspective published in EXO
We are pleased to share the publication of:
Anchoring virtual cells on gene programs: from biological networks to patient digital twins
Led by Dr. Jie Liao, Zhejiang University.
🔗Read: www.sciexplor.com/exo/articles...
#VirtualCell #Spatialbiology #SingleCell
June 16, 2026 at 9:44 AM
Glad to see multi-cell, multi-modal model attempted.

C2S-scale extends Cell2Sentences (C2S), a previous #virtualcell model, to 27B parameters, training on a 1B token Multi-modal dataset with a context length of 8192 (this needs to increase too).

www.biorxiv.org/content/10.1...
Scaling Large Language Models for Next-Generation Single-Cell Analysis
Single-cell RNA sequencing has transformed our understanding of cellular diversity, yet current single-cell foundation models (scFMs) remain limited in their scalability, flexibility across diverse ta...
www.biorxiv.org
April 18, 2025 at 3:16 PM