BioSimBench (CellType, 2026-11-04): scores LMs on held-out cellular responses to drugs, knockdowns and immune signals vs real lab measurements. Five tracks; pairs with BioSimGym (NVIDIA NeMo RL). toolome.bio/tools/biosimbench/ #VirtualCell #SingleCell
November 6, 2026 at 4:15 AM
BioSimBench (CellType, 2026-11-04): scores LMs on held-out cellular responses to drugs, knockdowns and immune signals vs real lab measurements. Five tracks; pairs with BioSimGym (NVIDIA NeMo RL). toolome.bio/tools/biosimbench/ #VirtualCell #SingleCell
Ginkgo Datapoints' VCPI just added DRUG-seq profiles for the 12,949-compound ReFRAME library. It now covers 26,000+ compounds in THP-1 cells, ~10,000 genes per well, CC-BY-4.0, built for virtual cell models.
toolome.bio/tools/vcpi/
#VirtualCell #DrugDiscovery #Transcriptomics
toolome.bio/tools/vcpi/
#VirtualCell #DrugDiscovery #Transcriptomics
VCPI (Virtual Cell Pharmacology Initiative): license, commercial use, paper — Datasets & benchmarks | Toolome
VCPI (Virtual Cell Pharmacology Initiative): Ginkgo Datapoints' open arrayed DRUG-seq resource for virtual cell models: 26,000+ compounds profiled in THP-1 cells, including the 12,949-compound ReFRAME...
toolome.bio
October 31, 2026 at 3:08 AM
Ginkgo Datapoints' VCPI just added DRUG-seq profiles for the 12,949-compound ReFRAME library. It now covers 26,000+ compounds in THP-1 cells, ~10,000 genes per well, CC-BY-4.0, built for virtual cell models.
toolome.bio/tools/vcpi/
#VirtualCell #DrugDiscovery #Transcriptomics
toolome.bio/tools/vcpi/
#VirtualCell #DrugDiscovery #Transcriptomics
PIE from Arc Institute is a virtual-cell model: it uses curated biological knowledge to predict perturbation responses in cell contexts it hasn't seen.
Perceiver IO architecture. Code on GitHub (CC-BY-NC-SA-4.0).
toolome.bio/tools/pie/ #SingleCell #VirtualCell
Perceiver IO architecture. Code on GitHub (CC-BY-NC-SA-4.0).
toolome.bio/tools/pie/ #SingleCell #VirtualCell
PIE (Arc Institute): license, commercial use, paper — Single-cell & foundation models | Toolome
PIE (Arc Institute): Virtual-cell model using curated biological knowledge to predict perturbation responses in unseen contexts. Commercial use: Non-commercial.
toolome.bio
October 30, 2026 at 3:18 AM
PIE from Arc Institute is a virtual-cell model: it uses curated biological knowledge to predict perturbation responses in cell contexts it hasn't seen.
Perceiver IO architecture. Code on GitHub (CC-BY-NC-SA-4.0).
toolome.bio/tools/pie/ #SingleCell #VirtualCell
Perceiver IO architecture. Code on GitHub (CC-BY-NC-SA-4.0).
toolome.bio/tools/pie/ #SingleCell #VirtualCell
#Virtualcell versus #medicine. I hear that a lot of medical treatments are formally untested, administered because they work and no one knows why or if at all. Alright, I see the place here for #AI and virtual cell projects. Go for it. Can the rest of us keep trying to #understand #biology?
October 11, 2026 at 7:11 PM
#Virtualcell versus #medicine. I hear that a lot of medical treatments are formally untested, administered because they work and no one knows why or if at all. Alright, I see the place here for #AI and virtual cell projects. Go for it. Can the rest of us keep trying to #understand #biology?
The notion of the #VirtualCell, is a good example of this. As any cell or developmental biologist will tell you, a cell is more than the aggregate of its gene and protein networks. And I agree with J Doudna that the statements that AI will ‘solve disease’ are widely exaggerated.
October 10, 2026 at 12:05 AM
The notion of the #VirtualCell, is a good example of this. As any cell or developmental biologist will tell you, a cell is more than the aggregate of its gene and protein networks. And I agree with J Doudna that the statements that AI will ‘solve disease’ are widely exaggerated.
A new survey shows 90% expect AI to crank out fresh work as budgets double. From DeepMind to NIH’s Virtual Biology Initiative, the race for a universal virtual cell is heating up. Curious? Dive in. #AIGeneration #VirtualCell #DeepMind
🔗 aidailypost.com/news/survey-...
🔗 aidailypost.com/news/survey-...
October 8, 2026 at 9:21 AM
A new survey shows 90% expect AI to crank out fresh work as budgets double. From DeepMind to NIH’s Virtual Biology Initiative, the race for a universal virtual cell is heating up. Curious? Dive in. #AIGeneration #VirtualCell #DeepMind
🔗 aidailypost.com/news/survey-...
🔗 aidailypost.com/news/survey-...
Zhenyu Ma, Xukai Jiang: PRAXIS-VirtualCell: A Programmable and Trustworthy Framework for Agentic Virtual Cell Experiments https://arxiv.org/abs/2609.29221 https://arxiv.org/pdf/2609.29221 https://arxiv.org/html/2609.29221
September 25, 2026 at 7:00 AM
Zhenyu Ma, Xukai Jiang: PRAXIS-VirtualCell: A Programmable and Trustworthy Framework for Agentic Virtual Cell Experiments https://arxiv.org/abs/2609.29221 https://arxiv.org/pdf/2609.29221 https://arxiv.org/html/2609.29221
@theinnovation.bsky.social #webinar: Virtual Cells in Oncology: Foundations and Advances.
Speaker: Shixiang Wang, MD
Date & Time: Aug. 29, 2026 | 21:00-22:00 (Beijing Time)
VooV meeting ID: 499-230-347
Join us this Saturday!
#VirtualCell #oncology
Speaker: Shixiang Wang, MD
Date & Time: Aug. 29, 2026 | 21:00-22:00 (Beijing Time)
VooV meeting ID: 499-230-347
Join us this Saturday!
#VirtualCell #oncology
August 27, 2026 at 2:18 AM
@theinnovation.bsky.social #webinar: Virtual Cells in Oncology: Foundations and Advances.
Speaker: Shixiang Wang, MD
Date & Time: Aug. 29, 2026 | 21:00-22:00 (Beijing Time)
VooV meeting ID: 499-230-347
Join us this Saturday!
#VirtualCell #oncology
Speaker: Shixiang Wang, MD
Date & Time: Aug. 29, 2026 | 21:00-22:00 (Beijing Time)
VooV meeting ID: 499-230-347
Join us this Saturday!
#VirtualCell #oncology
AIDO Cell simulates a whole human cell, DNA to structure, and remembers each step. Bold claim; wet-lab proof is still pending. Read the breakdown. #AIinBiology #VirtualCell #DrugDiscovery
artificialscience.org/2026/08/ai-v...
artificialscience.org/2026/08/ai-v...
A Nobel Laureate's AI Just Tried to Simulate a Whole Human Cell — Artificial Science
GenBio AI's AIDO Cell is a 'world model' that simulates a human cell across scales, from DNA to shape. Here's what it does, why it matters, and what still needs proving.
artificialscience.org
August 25, 2026 at 5:53 AM
AIDO Cell simulates a whole human cell, DNA to structure, and remembers each step. Bold claim; wet-lab proof is still pending. Read the breakdown. #AIinBiology #VirtualCell #DrugDiscovery
artificialscience.org/2026/08/ai-v...
artificialscience.org/2026/08/ai-v...
AI Model Makes Developmental Paths of Cells Traceable
An international research team, led by Prof. Fabian Theis, #HelmholtzMunich & @tum.de, has developed #RegVelo, an #AI-based model that can reconstruct developmental paths of cells.
👉 t1p.de/r6wgl
#VirtualCell
An international research team, led by Prof. Fabian Theis, #HelmholtzMunich & @tum.de, has developed #RegVelo, an #AI-based model that can reconstruct developmental paths of cells.
👉 t1p.de/r6wgl
#VirtualCell
May 12, 2026 at 4:36 AM
AI Model Makes Developmental Paths of Cells Traceable
An international research team, led by Prof. Fabian Theis, #HelmholtzMunich & @tum.de, has developed #RegVelo, an #AI-based model that can reconstruct developmental paths of cells.
👉 t1p.de/r6wgl
#VirtualCell
An international research team, led by Prof. Fabian Theis, #HelmholtzMunich & @tum.de, has developed #RegVelo, an #AI-based model that can reconstruct developmental paths of cells.
👉 t1p.de/r6wgl
#VirtualCell
Mapping the Kidney at Single-Cell Resolution 🤖
#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.
👉 t1p.de/yf554
#CellAtlas
#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.
👉 t1p.de/yf554
#CellAtlas
March 5, 2026 at 9:35 AM
Mapping the Kidney at Single-Cell Resolution 🤖
#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.
👉 t1p.de/yf554
#CellAtlas
#HelmholtzMunich and #Novartis Biomedical Research are launching a four-year collaboration to advance #KidneyDisease research with #AI-driven modeling, #VirtualCell simulations, & large-scale perturbation analysis.
👉 t1p.de/yf554
#CellAtlas
The #Evidence has been growing that the #Universe is #Infinite but it may all come crashing down : Medium
‘#VirtualCell’ captures the most-basic #Process of #Life: #Bacterial #Division : Nature
#Peptides are everywhere. Here’s what you need to know: Tech Review
knowledgezone.co.in/resources/bo...
‘#VirtualCell’ captures the most-basic #Process of #Life: #Bacterial #Division : Nature
#Peptides are everywhere. Here’s what you need to know: Tech Review
knowledgezone.co.in/resources/bo...
March 20, 2026 at 6:32 AM
The #Evidence has been growing that the #Universe is #Infinite but it may all come crashing down : Medium
‘#VirtualCell’ captures the most-basic #Process of #Life: #Bacterial #Division : Nature
#Peptides are everywhere. Here’s what you need to know: Tech Review
knowledgezone.co.in/resources/bo...
‘#VirtualCell’ captures the most-basic #Process of #Life: #Bacterial #Division : Nature
#Peptides are everywhere. Here’s what you need to know: Tech Review
knowledgezone.co.in/resources/bo...
Gene programs are the missing link for interpretable virtual cells.
This framework maps perturbations to phenotypes & paves the way for patient digital twins.
Read more: www.sciexplor.com/exo/articles...
#VirtualCell #GenePrograms #SingleCell #Genomics #SpatialOmics #EXOBeyondtheCell
This framework maps perturbations to phenotypes & paves the way for patient digital twins.
Read more: www.sciexplor.com/exo/articles...
#VirtualCell #GenePrograms #SingleCell #Genomics #SpatialOmics #EXOBeyondtheCell
June 26, 2026 at 2:38 AM
Gene programs are the missing link for interpretable virtual cells.
This framework maps perturbations to phenotypes & paves the way for patient digital twins.
Read more: www.sciexplor.com/exo/articles...
#VirtualCell #GenePrograms #SingleCell #Genomics #SpatialOmics #EXOBeyondtheCell
This framework maps perturbations to phenotypes & paves the way for patient digital twins.
Read more: www.sciexplor.com/exo/articles...
#VirtualCell #GenePrograms #SingleCell #Genomics #SpatialOmics #EXOBeyondtheCell
🎉New Perspective published in EXO
We are pleased to share the publication of:
Anchoring virtual cells on gene programs: from biological networks to patient digital twins
Led by Dr. Jie Liao, Zhejiang University.
🔗Read: www.sciexplor.com/exo/articles...
#VirtualCell #Spatialbiology #SingleCell
We are pleased to share the publication of:
Anchoring virtual cells on gene programs: from biological networks to patient digital twins
Led by Dr. Jie Liao, Zhejiang University.
🔗Read: www.sciexplor.com/exo/articles...
#VirtualCell #Spatialbiology #SingleCell
June 16, 2026 at 9:44 AM
🎉New Perspective published in EXO
We are pleased to share the publication of:
Anchoring virtual cells on gene programs: from biological networks to patient digital twins
Led by Dr. Jie Liao, Zhejiang University.
🔗Read: www.sciexplor.com/exo/articles...
#VirtualCell #Spatialbiology #SingleCell
We are pleased to share the publication of:
Anchoring virtual cells on gene programs: from biological networks to patient digital twins
Led by Dr. Jie Liao, Zhejiang University.
🔗Read: www.sciexplor.com/exo/articles...
#VirtualCell #Spatialbiology #SingleCell
🚀 Recursion has been laying the foundation for a virtual cell from day one – including massive-scale, proprietary biological & chemical datasets, AI models & one of the industry’s most powerful supercomputers. Learn about our progress & what's next: www.recursion.com/news/since-i... #virtualcell
December 4, 2025 at 4:51 PM
🚀 Recursion has been laying the foundation for a virtual cell from day one – including massive-scale, proprietary biological & chemical datasets, AI models & one of the industry’s most powerful supercomputers. Learn about our progress & what's next: www.recursion.com/news/since-i... #virtualcell
🎉 Daniel Cohen, President of Valence Labs (@valenceai.bsky.social),
Recursion’s AI research engine, has been named a “Rising Leader” by Citeline. #TechBio #AI #ML #research #virtualcell
👉Read more: insights.citeline.com/in-vivo/lead...
Recursion’s AI research engine, has been named a “Rising Leader” by Citeline. #TechBio #AI #ML #research #virtualcell
👉Read more: insights.citeline.com/in-vivo/lead...
September 5, 2025 at 1:45 PM
🎉 Daniel Cohen, President of Valence Labs (@valenceai.bsky.social),
Recursion’s AI research engine, has been named a “Rising Leader” by Citeline. #TechBio #AI #ML #research #virtualcell
👉Read more: insights.citeline.com/in-vivo/lead...
Recursion’s AI research engine, has been named a “Rising Leader” by Citeline. #TechBio #AI #ML #research #virtualcell
👉Read more: insights.citeline.com/in-vivo/lead...
🔥 REGISTER NOW: Westlake Symposium on AI Proteomics & Virtual Cell!
🔗https://docs.qq.com/form/page/DTUxvaW5RSFJBeUx4
🗓️ Oct 8-9, 2025
📍 Westlake University, Hangzhou, China
📧zhuhuinan@westlake.edu.cn
Join global pioneers at the intersection of AI+Life Science! #AIProteomics #VirtualCell #AIinScience
🔗https://docs.qq.com/form/page/DTUxvaW5RSFJBeUx4
🗓️ Oct 8-9, 2025
📍 Westlake University, Hangzhou, China
📧zhuhuinan@westlake.edu.cn
Join global pioneers at the intersection of AI+Life Science! #AIProteomics #VirtualCell #AIinScience
July 3, 2025 at 12:35 PM
🔥 REGISTER NOW: Westlake Symposium on AI Proteomics & Virtual Cell!
🔗https://docs.qq.com/form/page/DTUxvaW5RSFJBeUx4
🗓️ Oct 8-9, 2025
📍 Westlake University, Hangzhou, China
📧zhuhuinan@westlake.edu.cn
Join global pioneers at the intersection of AI+Life Science! #AIProteomics #VirtualCell #AIinScience
🔗https://docs.qq.com/form/page/DTUxvaW5RSFJBeUx4
🗓️ Oct 8-9, 2025
📍 Westlake University, Hangzhou, China
📧zhuhuinan@westlake.edu.cn
Join global pioneers at the intersection of AI+Life Science! #AIProteomics #VirtualCell #AIinScience
200+ live for our series kickoff! 🚀
Huge thanks to everyone who joined our Virtual Biology Community Meetup yesterday.
Missed it? Catch the replay: 📺 youtu.be/ptMy4yhZT8Q
#virtualbiology #decodingbiology #virtualcell #virtualizeexperiments #aiforbiology #drugdiscovery
Huge thanks to everyone who joined our Virtual Biology Community Meetup yesterday.
Missed it? Catch the replay: 📺 youtu.be/ptMy4yhZT8Q
#virtualbiology #decodingbiology #virtualcell #virtualizeexperiments #aiforbiology #drugdiscovery
Virtual Biology Community Meetup
YouTube video by Turbine Simulated Cell Technologies
youtu.be
January 20, 2026 at 4:28 PM
200+ live for our series kickoff! 🚀
Huge thanks to everyone who joined our Virtual Biology Community Meetup yesterday.
Missed it? Catch the replay: 📺 youtu.be/ptMy4yhZT8Q
#virtualbiology #decodingbiology #virtualcell #virtualizeexperiments #aiforbiology #drugdiscovery
Huge thanks to everyone who joined our Virtual Biology Community Meetup yesterday.
Missed it? Catch the replay: 📺 youtu.be/ptMy4yhZT8Q
#virtualbiology #decodingbiology #virtualcell #virtualizeexperiments #aiforbiology #drugdiscovery
Glad to see multi-cell, multi-modal model attempted.
C2S-scale extends Cell2Sentences (C2S), a previous #virtualcell model, to 27B parameters, training on a 1B token Multi-modal dataset with a context length of 8192 (this needs to increase too).
www.biorxiv.org/content/10.1...
C2S-scale extends Cell2Sentences (C2S), a previous #virtualcell model, to 27B parameters, training on a 1B token Multi-modal dataset with a context length of 8192 (this needs to increase too).
www.biorxiv.org/content/10.1...
Scaling Large Language Models for Next-Generation Single-Cell Analysis
Single-cell RNA sequencing has transformed our understanding of cellular diversity, yet current single-cell foundation models (scFMs) remain limited in their scalability, flexibility across diverse ta...
www.biorxiv.org
April 18, 2025 at 3:16 PM
Glad to see multi-cell, multi-modal model attempted.
C2S-scale extends Cell2Sentences (C2S), a previous #virtualcell model, to 27B parameters, training on a 1B token Multi-modal dataset with a context length of 8192 (this needs to increase too).
www.biorxiv.org/content/10.1...
C2S-scale extends Cell2Sentences (C2S), a previous #virtualcell model, to 27B parameters, training on a 1B token Multi-modal dataset with a context length of 8192 (this needs to increase too).
www.biorxiv.org/content/10.1...
Reflecting on #virtualcell: Given that no cell is an island, what's the chance of inferring biology looking at just a single cell's transcriptome? As a recent preprint (arxiv.org/abs/2503.03485) said, "After all, we do not have healthy or diseased annotations for individual cells." #singlecell
TEDDY: A Family Of Foundation Models For Understanding Single Cell Biology
Understanding the biological mechanism of disease is critical for medicine, and in particular drug discovery. AI-powered analysis of genome-scale biological data hold great potential in this regard. T...
arxiv.org
April 18, 2025 at 11:54 AM
Reflecting on #virtualcell: Given that no cell is an island, what's the chance of inferring biology looking at just a single cell's transcriptome? As a recent preprint (arxiv.org/abs/2503.03485) said, "After all, we do not have healthy or diseased annotations for individual cells." #singlecell
The preprint detailing the results of the #SchmidtCenter Cancer Immunotherapy Machine Learning Competition is online!
@broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell
www.biorxiv.org/content/10.6...
@broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell
www.biorxiv.org/content/10.6...
May 22, 2026 at 10:43 PM
The preprint detailing the results of the #SchmidtCenter Cancer Immunotherapy Machine Learning Competition is online!
@broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell
www.biorxiv.org/content/10.6...
@broadinstitute.org #MachineLearning #CancerImmunotherapy #ComputationalBiology #PerturbSeq #AI4Science #VirtualCell
www.biorxiv.org/content/10.6...
Biology is spatial —and so shall a foundation model be.🌍I’m excited to share OCTO-VirtualCell, our latest model and the Celleporter platform @Noetik —work I’m deeply proud of and believe is transformative for spatial biology.
report: noetik.ai/octo-vc
demo: celleporter.noetik.ai
report: noetik.ai/octo-vc
demo: celleporter.noetik.ai
OCTO-vc
Celleporter is a simulator of spatial biology that predicts gene expression patterns for virtual cells embedded in patient tissue samples.
noetik.ai
December 18, 2024 at 5:16 PM
Biology is spatial —and so shall a foundation model be.🌍I’m excited to share OCTO-VirtualCell, our latest model and the Celleporter platform @Noetik —work I’m deeply proud of and believe is transformative for spatial biology.
report: noetik.ai/octo-vc
demo: celleporter.noetik.ai
report: noetik.ai/octo-vc
demo: celleporter.noetik.ai