Why? The neighbors talk back.
Neutrophils secrete oncostatin M (OSM). OSM does something clever: it switches on mesenchymal genes (SNAI1, ZEB1) while keeping the epithelial program (∆Np63, KLF5) alive.
The result: cells held in a hybrid state.
5/15
Neutrophils secrete oncostatin M (OSM). OSM does something clever: it switches on mesenchymal genes (SNAI1, ZEB1) while keeping the epithelial program (∆Np63, KLF5) alive.
The result: cells held in a hybrid state.
5/15
November 2, 2026 at 10:53 AM
Why? The neighbors talk back.
Neutrophils secrete oncostatin M (OSM). OSM does something clever: it switches on mesenchymal genes (SNAI1, ZEB1) while keeping the epithelial program (∆Np63, KLF5) alive.
The result: cells held in a hybrid state.
5/15
Neutrophils secrete oncostatin M (OSM). OSM does something clever: it switches on mesenchymal genes (SNAI1, ZEB1) while keeping the epithelial program (∆Np63, KLF5) alive.
The result: cells held in a hybrid state.
5/15
The authors included RRIDs in their in The Journal of Biochemistry paper! Thanks for making your methods matter! #accelerateopenscience #methodsmatter #BetterScience
TGF-β downregulates E-cadherin expression via a novel ZEB1-dependent mechanism
Read the full paper: TGF-β downregulates E-cadherin expression via a novel ZEB1-dependent mechanism
doi.org
October 30, 2026 at 7:08 AM
The authors included RRIDs in their in The Journal of Biochemistry paper! Thanks for making your methods matter! #accelerateopenscience #methodsmatter #BetterScience
Complementary Diagnostic Value of ZEB1 and CK7 in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma www.ovid.com/10.1097/PAI....
Complementary Diagnostic Value of ZEB1 and CK7 in... : Applied Immunohistochemistry & Molecular Morphology
Renal oncocytoma (RO) is a benign renal epithelial tumor that may closely mimic chromophobe renal cell carcinoma (chRCC), particularly in limited...
www.ovid.com
October 14, 2026 at 12:35 AM
Complementary Diagnostic Value of ZEB1 and CK7 in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma www.ovid.com/10.1097/PAI....
ZEB1, crucial for erythroid maturation, modulates the GATA2-KLF1 switch. Its loss hinders progenitor proliferation in mice and humans. PMID:42331751, Nucleic Acids Res 2026, @NAR_Open https://doi.org/10.1093/nar/gkag613 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1093/nar/gkag613
No description available
doi.org
September 5, 2026 at 3:00 AM
Naringin, a natural flavonoid ZEB1 inhibitor, reverses the diabetes-exacerbated vascular endothelial dysfunction to attenuate atherosclerosis progression.
Read here ➡️ doi.org/10.2337/db25-1059
Read here ➡️ doi.org/10.2337/db25-1059
August 22, 2026 at 11:55 PM
Naringin, a natural flavonoid ZEB1 inhibitor, reverses the diabetes-exacerbated vascular endothelial dysfunction to attenuate atherosclerosis progression.
Read here ➡️ doi.org/10.2337/db25-1059
Read here ➡️ doi.org/10.2337/db25-1059
what if we kissed at the zeb1 movie
a brown dog is sitting next to a white table and holding onto a shoe .
ALT: a brown dog is sitting next to a white table and holding onto a shoe .
media.tenor.com
February 12, 2025 at 3:15 AM
what if we kissed at the zeb1 movie
but did u say zeb1
a young man wearing a white and black adidas jacket is making a face .
ALT: a young man wearing a white and black adidas jacket is making a face .
media.tenor.com
December 18, 2024 at 9:08 PM
but did u say zeb1
Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14 #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.05.10.724074v1
https://www.biorxiv.org/content/10.64898/2026.05.10.724074v1
May 13, 2026 at 4:00 PM
Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14 #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.05.10.724074v1
https://www.biorxiv.org/content/10.64898/2026.05.10.724074v1
Integrative transcriptomic and single-nucleus analyses identify ZEB1 as a key regulator of ovarian aging in granulosa cells #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-9045470/latest
https://www.researchsquare.com/article/rs-9045470/latest
April 30, 2026 at 4:00 PM
Integrative transcriptomic and single-nucleus analyses identify ZEB1 as a key regulator of ovarian aging in granulosa cells #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-9045470/latest
https://www.researchsquare.com/article/rs-9045470/latest
Congratulations to our colleague Dr. Benjamin Kleaveland (@BenKleaveland) and colleagues on their new paper, "Derepression of a single microRNA target causes female infertility in mice," in Nucleic Acids Research!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Derepression of a single microRNA target causes female infertility in mice
Abstract. The miR-200a and miR-200b families control mouse ovulation and are essential for female fertility. The ZEB1 transcription factor is a conserved t
academic.oup.com
January 24, 2026 at 6:24 PM
Congratulations to our colleague Dr. Benjamin Kleaveland (@BenKleaveland) and colleagues on their new paper, "Derepression of a single microRNA target causes female infertility in mice," in Nucleic Acids Research!
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
#ecology
Decreased E-cadherin,
increased Vimentin, N-cadherin, ZEB1, and Twist density
in tumor tissues,
increased CYP1B1 as a key factor promoting
EMT (epithelial–mesenchymal transition)
Cadmium exposure
promotes
breast cancer progression and metastasis
.
www.sciencedirect.com/science/arti...
Decreased E-cadherin,
increased Vimentin, N-cadherin, ZEB1, and Twist density
in tumor tissues,
increased CYP1B1 as a key factor promoting
EMT (epithelial–mesenchymal transition)
Cadmium exposure
promotes
breast cancer progression and metastasis
.
www.sciencedirect.com/science/arti...
Long-term cadmium exposure induces epithelial-mesenchymal transition in breast cancer cells by activating CYP1B1-mediated glutamine metabolic reprogramming in BT474 cells and MMTV-Erbb2 mice
Cadmium (Cd) exposure is known to enhance breast cancer (BC) progression. Cd promotes epithelial–mesenchymal transition (EMT) in BC cells, facilitatin…
www.sciencedirect.com
March 19, 2025 at 4:11 AM
#ecology
Decreased E-cadherin,
increased Vimentin, N-cadherin, ZEB1, and Twist density
in tumor tissues,
increased CYP1B1 as a key factor promoting
EMT (epithelial–mesenchymal transition)
Cadmium exposure
promotes
breast cancer progression and metastasis
.
www.sciencedirect.com/science/arti...
Decreased E-cadherin,
increased Vimentin, N-cadherin, ZEB1, and Twist density
in tumor tissues,
increased CYP1B1 as a key factor promoting
EMT (epithelial–mesenchymal transition)
Cadmium exposure
promotes
breast cancer progression and metastasis
.
www.sciencedirect.com/science/arti...
RT @estate44: Tea partier fears Facebook is covertly conditioning people to tolerate Islam #p2 <a href="http://post.ly/zeb1" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://post.ly/zeb1
November 6, 2024 at 9:28 AM
RT @estate44: Tea partier fears Facebook is covertly conditioning people to tolerate Islam #p2 <a href="http://post.ly/zeb1" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://post.ly/zeb1
We used two in vitro TNBC models, in which EMT-driven plasticity was either induced by ZEB1 expression, or spontaneously occurred upon oncogenic transformation. We used single-cell cloning experiments and scRNA-seq data pre and post doxorubicin treatment to investigate phenotype dynamics.
February 5, 2025 at 1:01 PM
We used two in vitro TNBC models, in which EMT-driven plasticity was either induced by ZEB1 expression, or spontaneously occurred upon oncogenic transformation. We used single-cell cloning experiments and scRNA-seq data pre and post doxorubicin treatment to investigate phenotype dynamics.
Loving the ZEB1 HBR survey in the 2017 @InstituteArch yearbook by @oatweet @edwardbiddulph
May 1, 2025 at 3:36 AM
Loving the ZEB1 HBR survey in the 2017 @InstituteArch yearbook by @oatweet @edwardbiddulph
Is it all MHC1/PDL1? Or just EMT? Well, we didn’t see differences in MHC1 or PDL1, and activation of Zeb1 could enhance tumor growth but didn’t exclude CD8+ T cells. This indicates unique features of immune suppression to Gli2 in tumors, in parallel to EMT.
February 24, 2025 at 7:01 PM
Is it all MHC1/PDL1? Or just EMT? Well, we didn’t see differences in MHC1 or PDL1, and activation of Zeb1 could enhance tumor growth but didn’t exclude CD8+ T cells. This indicates unique features of immune suppression to Gli2 in tumors, in parallel to EMT.
ZEB1 drives chemo-immune resistance in pancreatic cancer; targeting it enhances therapy effectiveness, boosts immune response, and improves survival.
by Zhang S, Hu Y (...) Liu M et 10 al. in J Clin Invest #MedSky
👉 get more here
📖 read the article: https://www.jci.org/articles/view/195970
by Zhang S, Hu Y (...) Liu M et 10 al. in J Clin Invest #MedSky
👉 get more here
📖 read the article: https://www.jci.org/articles/view/195970
September 18, 2025 at 4:33 AM
ZEB1 drives chemo-immune resistance in pancreatic cancer; targeting it enhances therapy effectiveness, boosts immune response, and improves survival.
by Zhang S, Hu Y (...) Liu M et 10 al. in J Clin Invest #MedSky
👉 get more here
📖 read the article: https://www.jci.org/articles/view/195970
by Zhang S, Hu Y (...) Liu M et 10 al. in J Clin Invest #MedSky
👉 get more here
📖 read the article: https://www.jci.org/articles/view/195970
We find that disrupting the miR-200–ZEB1 double-negative feedback loop leads to anovulatory infertility and widespread gene expression changes in the mouse pituitary. This study demonstrates the dramatic phenotypic and molecular consequences of disrupting repression of a single miRNA target. (2/2)
January 14, 2026 at 9:11 PM
We find that disrupting the miR-200–ZEB1 double-negative feedback loop leads to anovulatory infertility and widespread gene expression changes in the mouse pituitary. This study demonstrates the dramatic phenotypic and molecular consequences of disrupting repression of a single miRNA target. (2/2)
ICYMI: Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation: Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a… #Cornea #Ophthalmology #Ophthotwitter
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a… #Cornea #Ophthalmology #Ophthotwitter
Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation
Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously unknown genetic alteration in the ZEB1 gene.
Methods:
Ophthalmic examinations and corneal…
dlvr.it
February 1, 2025 at 9:59 PM
ICYMI: Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation: Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a… #Cornea #Ophthalmology #Ophthotwitter
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a… #Cornea #Ophthalmology #Ophthotwitter
Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation: Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously… #Cornea #Ophthalmology #Ophthotwitter
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously… #Cornea #Ophthalmology #Ophthotwitter
Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation
Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously unknown genetic alteration in the ZEB1 gene.
Methods:
Ophthalmic examinations and corneal…
dlvr.it
January 30, 2025 at 9:58 PM
Familial Steep Corneas in Posterior Polymorphous Corneal Dystrophy 3 Due to a Novel ZEB1 Gene Mutation: Purpose:
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously… #Cornea #Ophthalmology #Ophthotwitter
To present 4 family members with posterior polymorphous corneal dystrophy (PPCD), nonkeratoconic steep corneas, and myopia caused by a previously… #Cornea #Ophthalmology #Ophthotwitter
i got you 🫡 open.spotify.com/playlist/191...
zeb1
Playlist · emm · 39 items
open.spotify.com
March 12, 2025 at 4:41 AM
i got you 🫡 open.spotify.com/playlist/191...
do they still make after mom is sleeping and if so how do i get zeb1 on it right now immediately
January 30, 2025 at 12:11 AM
do they still make after mom is sleeping and if so how do i get zeb1 on it right now immediately
not one visual hole in zeb1
January 25, 2025 at 5:41 AM
not one visual hole in zeb1
im really in this zeb1 shit huh
December 17, 2024 at 7:55 PM
im really in this zeb1 shit huh
ZEB1:p (zinc finger E-box binding homeobox 1) is a transcription factor that has a couple of peripheral zinc fingers & a central homeobox domain. The pS/T acceptor occupancy pattern is pretty much what I would expect, esp. the rather artful pattern cward of the homeobox. #proteomics
November 5, 2025 at 1:50 PM
ZEB1:p (zinc finger E-box binding homeobox 1) is a transcription factor that has a couple of peripheral zinc fingers & a central homeobox domain. The pS/T acceptor occupancy pattern is pretty much what I would expect, esp. the rather artful pattern cward of the homeobox. #proteomics