#adenomas
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thelancetendo.bsky.social
#Prolactin-secreting lactotroph #pituitary #adenomas, also known as #prolactinomas, account for more than half of all pituitary adenomas. #Hyperprolactinaemia due to causes other than a prolactinoma is increasingly being recognised www.thelancet.com/journals/lan...
#prolactinomas

#MedSky #EndoSky
October 15, 2026 at 4:15 PM
thelancetendo.bsky.social
New—Multidisciplinary care of #pituitary #adenomas www.thelancet.com/journals/lan...
#FREE to read

#MedSky #EndoSky #OncSky
Multidisciplinary care of pituitary adenomas
Pituitary adenomas are a heterogeneous group of neoplasms with complex and diverse biological behaviour. These tumours, especially those secreting active hormones, affect nearly every organ system, in...
www.thelancet.com
October 12, 2026 at 8:42 AM
thelancetendo.bsky.social
Multiple endocrine neoplasia type 1 (#MEN1) is characterised by combined occurrence of #parathyroid tumours, #duodenopancreatic #neuroendocrine tumours, and anterior #pituitary adenomas www.thelancet.com/journals/lan...
#FREE to read with registration (also FREE)

#MedSky #EndoSky #OncSky
Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice
Multiple endocrine neoplasia type 1 (MEN1) is characterised by combined occurrence of parathyroid tumours, duodenopancreatic neuroendocrine tumours, and anterior pituitary adenomas. Some patients migh...
www.thelancet.com
October 15, 2026 at 3:58 PM
revistamfandalucia.bsky.social
Intervalos de colonoscopia e incidencia de cáncer colorrectal tras extirpación de adenomas
www.nejm.org/doi/full/10....
PMID 42748427
www.nejm.org
October 15, 2026 at 10:53 AM
revistamfandalucia.bsky.social
Cuando más no es mejor – vigilancia con colonoscopia tras adenomas de alto riesgo
www.nejm.org/doi/full/10....
PMID 42748433
www.nejm.org
October 15, 2026 at 10:54 AM
frontierresearch.co
Somatic mutations are found in only 15% of pituitary adenomas. In those causing Cushing's disease, a neurodevelopmental phosphoprotein program is reactivated and the PP2A inhibitor PPP1R17 overexpressed; in mouse pituitary cells overexpressing it, fingolimod reversed the overgrowth.

#endocrinology
Phosphoproteomic dysregulation promotes tumor proliferation in Cushing’s disease | Frontier
The authors built paired datasets of human pituitary adenomas that cause Cushing's disease and en-route margin tissue from adult human pituitary glands, and…
frontierresearch.co
October 12, 2026 at 8:00 AM
oddlytruejp.bsky.social
Curcumin and Colon Polyps: A Japanese Trial Missed Its Main Goal but Saw 44% Fewer Large Ones
A 26-site, two-year double-blind trial in Japan found high-absorption curcumin did not cut colon polyp recurrence overall (risk ratio 0.98), but large adenomas were about 44% lower. Not proof of cancer prevention.
kantenna.com
October 11, 2026 at 12:00 AM
postnatodepression.bsky.social
Hungry Bone Syndrome sounds like something a child would make up to get out of PE.
Hungry bone syndrome is a term used to describe the hypocalcaemia (often severe and symptomatic) that can follow the treatment of conditions in which hypercalcae-mia has been associated with increased bone resorption. With parathyroid adenomas and in hypercalcaemic thyrotoxicosis, prolonged suppression of normal PTH production may contribute to the hypocalcaemia. Hungry bone syndrome should be anticipated and should be preventable by the provision of vitamin D and calcium before and after sur-gery; this is also the treatment if the condition does
October 6, 2026 at 8:17 AM
chucky.bsky.social
Prevalence and risk of colorectal adenomas and colorectal cancer among Thai population aged under 50 years
Prevalence and risk of colorectal adenomas and colorectal cancer among Thai population aged under 50 years
chuckyscarnage.tech.blog
October 1, 2026 at 10:42 AM
ucldiscovery.bsky.social
Open Access UCL Research: Pituitary Society Delphi consensus on the role of radiotherapy for pituitary adenomas discovery.ucl.ac.uk/id/eprint/10...
Pituitary Society Delphi consensus on the role of radiotherapy for pituitary adenomas - UCL Discovery
UCL Discovery is UCL's open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
discovery.ucl.ac.uk
September 28, 2026 at 2:38 PM
aga-gastro.bsky.social
Beyond adenoma count: Both number and size shape future risk. Small (6–9mm) adenomas carry higher risk, supporting more refined colonoscopy surveillance strategies. Click the link to read more:
🔗 https://ow.ly/OEns50ZShNv
September 28, 2026 at 4:30 PM
karavitakin.bsky.social
Paper just out at EJE - open access - doi.org/10.1093/ejen...
“Pituitary adenomas in older patients - approaches, challenges and future directions”
An important topic given the increase in ageing population
European multinational collaborative work - Many thanks to my co-authors!
September 25, 2026 at 6:50 PM
nejm.org
After high-risk adenomas are removed at colonoscopy, guidelines recommend surveillance colonoscopies starting at 3 years, but this screening interval is based on limited evidence. Research findings from the EPoS II trial are summarized in a new Quick Take video. https://nej.md/46XXNwO
A visual representation of the EPoS II trial, which compared different colonoscopy surveillance intervals for patients with high-risk adenomas removed at colonoscopy.
September 23, 2026 at 1:00 PM
thiemeindia.bsky.social
The Neurosurgery Subintern Tumor Reading List on MedOne Neurosurgery brings together focused chapters on brain tumor emergencies, surgical principles, metastases, radiosurgery, pituitary adenomas and spinal tumors.

Learn more: medone-neurosurgery.thieme.com
September 24, 2026 at 8:46 AM
davidmogeladze.bsky.social
www.cancertherapyadvisor.com/news/colorec...
New Study Supports 5-Year Colonoscopy Interval After Adenoma Removal
In this interim analysis of a 10-year noninferiority trial, researchers evaluate 3-year compared with 5-year colonoscopy intervals after removal of high-risk adenomas.
www.cancertherapyadvisor.com
September 23, 2026 at 4:13 PM
sweetpapers.proteaglyco.com
Evaluation of acylated/deacylated ghrelin, CCL20/CCR6 concentration, and IgG N-Glycan alterations in different dysplasia grades of colon adenoma
#glycotime #GlycoconjugateJournal
Evaluation of acylated/deacylated ghrelin, CCL20/CCR6 concentration, and IgG N-Glycan alterations in different dysplasia grades of colon adenoma
Colorectal adenomas represent precursor lesions in the adenoma–carcinoma sequence and are characterized by chronic low-grade inflammation. Chemokine
link.springer.com
September 23, 2026 at 4:45 PM
gastroagi.bsky.social
What if adenomas are being missed not because they are invisible—but because we are looking in the wrong place?

The EYE-SIGHT trial tests whether peripheral gaze feedback can sharpen detection during colonoscopy.
EYE-SIGHT Trial: Gaze and Adenoma Detection
A multicenter RCT found real-time peripheral gaze feedback improved adenoma and polyp detection during colonoscopy without longer observation time.
gastroagi.com
September 21, 2026 at 12:22 PM
nejm.org
In this planned interim analysis of a randomized trial, first surveillance colonoscopy at 5 years after the removal of high-risk adenomas was noninferior to first colonoscopy at 3 years for the incidence of colorectal cancer. Full EPoS II trial results and Research Summary: https://nej.md/4yCEnJN
This image contains an excerpt from the Research Summary "Colonoscopy Intervals and Colorectal Cancer after Adenoma Removal" published in the New England Journal of Medicine. It includes a diagram of the colon with adenoma removal highlighted. Text states there are 10,799 adult patients with a mean age of 62 years, 65% men and 35% women. Two groups are shown: a 5-year group with less frequent surveillance (5,398 individuals) and a 3-year group with more frequent surveillance (5,401 individuals). A prompt to read the full Research Summary at NEJM.org sits at the bottom.
September 20, 2026 at 4:00 PM
medpagetoday.com
Surveillance colonoscopy beginning 5 years after removal of high-risk adenomas is just as effective for detecting colorectal cancer as a shorter 3-year interval, an interim analysis of an ongoing noninferiority trial showed.
https://www.medpagetoday.com/gastroenterology/coloncancer/123027
Less Frequent Colonoscopy After Polyp Removal Could Be the Way to Go, Study Suggests
Findings show similar incidence of colorectal cancer with colonoscopy at 3 and 5 years
www.medpagetoday.com
September 17, 2026 at 1:41 PM
thelancetendo.bsky.social
The aberrant expression of diverse G-protein coupled receptors (GPCRs) & their ligands play an important role in the over-function of various endocrine tumours www.thelancet.com/journals/lan...
#cortisol-secreting primary bilateral macronodular #adrenal hyperplasia #unilateral #adenomas

#EndoSky
September 17, 2026 at 10:50 AM
ciberisciii.bsky.social
Retrasar de tres a cinco años la primera colonoscopia de vigilancia tras la extirpación de adenomas avanzados no aumenta el riesgo de desarrollar cáncer colorrectal ni de morir por esta enfermedad 🕒

🔗 www.ciberisciii.es/noticias/dem...
September 17, 2026 at 7:58 AM
gastroagi.bsky.social
Do high-risk adenomas really need 3-year surveillance?

EPoS II asks whether 5 years could be enough—with long-term CRC outcomes ultimately deciding the answer.

#Colonoscopy #ColorectalCancer #Endoscopy #MedSky
September 17, 2026 at 5:27 AM
sciencex.bsky.social
After high-risk adenomas were removed, five-year colorectal cancer risk was 0.77% with first follow-up at five years and 0.82% at three years. The longer interval avoided nearly 4,200 exams. doi.org/hcjrm3
Trial suggests less frequent colonoscopies may safely follow removal of high-risk polyps
Every year, around 1.9 million people worldwide are diagnosed with bowel cancer. To prevent the disease, many countries have introduced screening programs that enable more polyps to be detected and removed before cancer develops.
medicalxpress.com
September 17, 2026 at 2:20 PM
nejm.org
In this planned interim analysis of a randomized trial, first surveillance colonoscopy at 5 years after the removal of high-risk adenomas was noninferior to first colonoscopy at 3 years for the incidence of colorectal cancer. Full EPoS II trial results: https://nej.md/4yCEnJN
A graph from an Original Article published in the New England Journal of Medicine article titled "Colonoscopy Intervals and Colorectal Cancer Incidence after Adenoma Removal." The graph shows the cumulative incidence of colorectal cancer in the two trial groups. The trial name, EPoS II, is in parentheses after the title. The NEJM identity sits at the bottom.
September 16, 2026 at 9:25 PM
drsteveradi.bsky.social
share.google/BNsmZ9w0OOGi...
Exciting! A blood test to detect pre-cancerous Advanced Adenomas…more to come on this for sure.
Blood test targets ‘Achilles’ heel’ of CRC screening, detects 81% of advanced adenomas
Researchers have developed a blood-based assay that could help identify individuals with precursor lesions for colorectal cancer, a known limitation of many blood-based screening tests.The assay, know...
share.google
September 14, 2026 at 5:12 PM