Nature Chemistry, Published online: 05 November 2026; doi:10.1038/s41557-026-02292-6Binuclear metalloenzymes remain underexplored for new-to-nature biocatalytic reactions. Now binuclear copper enzymes, particularly a Bacillus megaterium tyrosinase, are used as a catalytic platform for stereoselective radical azidation, bromination, chlorination and isothiocyanation reactions, expanding metalloenzyme catalysis beyond mononuclear systems.

AbstractUnplanned potable reuse introduces effluent-derived organic matter (EfOM) into drinking water sources. While conventional coagulation partially removes EfOM, the residual fraction undergoes chlorination and may form toxic disinfection byproducts (DBPs) that escape current monitoring. However, the molecular mechanisms by which EfOM alters DBP formation pathways remain poorly understood. Here, we combine ultrahigh-resolution mass spectrometry with reaction network analysis to reveal that EfOM significantly redirects chlorine pathways. Compared to EfOM-free surface water, the presence of 20% EfOM decreases direct halogenation pathways (addition and substitution) from 4.2% to 1.8% of total transformation events. This shift occurs because EfOM introduces reduced, high-molecular-weight, heteroatom-rich molecules that cannot be directly halogenated; they require HOCl-driven oxidative fragmentation to generate halogenation-susceptible intermediates. Consequently, chlorinated finished water accumulates sulfur-containing DBPs (CHOS compounds, with relative intensity increasing from 35% to 60%) and complex “orphan” DBPs lacking identifiable precursors (with molecular features linked to elevated toxicity). These findings highlight an urgent need to update DBP monitoring frameworks to include unregulated sulfur-containing and orphan byproducts in de facto reuse scenarios.

The Trichloroacetyl Chloride market delivers a high-velocity polymer and chemical intermediary value chain, underpinning downstream acylation, chlorination, and pharmaceutical synthesis. This report c...

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11335-4Back-to-monomer depolymerization of silicones by deoxygenative chlorination

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11335-4Back-to-monomer depolymerization of silicones by deoxygenative chlorination

Nature, Published online: 28 October 2026; doi:10.1038/s41586-026-11335-4 Back-to-monomer depolymerization of silicones by deoxygenative chlorination

The global Ethylene Dichloride market was valued at US$ 34.05 billion in 2025 and is expected to reach US$ 39.5 billion by 2034; it is estimated to record a CAGR of 1.66% during 2026–2034. Ethylene Dichloride (EDC), systematically known as 1,2-dichloroethane, serves as a primary chemical intermediate manufactured through the direct chlorination or oxychlorination of ethylene. It acts as the key precursor in the synthesis of vinyl chloride monomer (VCM), which is subsequently polymerized to produce polyvinyl chloride (PVC) used extensively across global construction, automotive, and packaging infrastructure.

Titanium Electrode for Salt Chlorinator: Why MMO Coated Anodes Outlast Others in Swimming Pool Electrolysis If you are sourcing electrodes for a salt water chlorination system, you face a critical decision: which anode material will survive the aggressive salt environment long enough to keep maintenance costs predictable — and which will leave you replacing components every season? The answer separates profitable pool equipment businesses from those bleeding money on reactive maintenance. The Salt Chlorinator Environment: Why It Destroys Most Electrodes A salt chlorinator works by electrolyzing dissolved sodium chloride (NaCl) to generate free chlorine, keeping pools sanitized without manual chemical dosing.