And the origin of eukaryotes is a really hot topic now.
November 1, 2026 at 4:50 PM
And the origin of eukaryotes is a really hot topic now.
OTD in 1977 Carl Woese and George Fox redrew the tree of life. They proposed a third “urkingdom”—the “archaebacteria”—in addition to eukaryotes and bacteria. Woese later called this taxon “Archea.”
AFAIK, he didn’t publish his famous tree diagram until the late 80s.
🐋🌱🧪 #HistSTM 🗃️🧠 #evobio 🐡
AFAIK, he didn’t publish his famous tree diagram until the late 80s.
🐋🌱🧪 #HistSTM 🗃️🧠 #evobio 🐡
November 2, 2026 at 4:16 PM
Capturing our closest archaeal relatives offers clues to the origin of eukaryotes - JAMSTEC
www.jamstec.go.jp/e/about/pres...
www.jamstec.go.jp/e/about/pres...
November 3, 2026 at 10:14 PM
Capturing our closest archaeal relatives offers clues to the origin of eukaryotes - JAMSTEC
www.jamstec.go.jp/e/about/pres...
www.jamstec.go.jp/e/about/pres...
Daniel continues the evolution session of #KNVMfall2026 highlighting heimdallarchaeial ancestry of eukaryotes
See their @nature.com paper
www.nature.com/articles/s41...
See their @nature.com paper
www.nature.com/articles/s41...
Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes - Nature
Analyses of multiple phylogenetic marker datasets of Asgard archaea provide insight into the transition from prokaryotes to eukaryotes, specifically placing eukaryotes within Asgard archaea and as a s...
www.nature.com
November 6, 2026 at 10:34 AM
Daniel continues the evolution session of #KNVMfall2026 highlighting heimdallarchaeial ancestry of eukaryotes
See their @nature.com paper
www.nature.com/articles/s41...
See their @nature.com paper
www.nature.com/articles/s41...
Going viral on reddit by claiming I'm a teacher and my students are so remedial they're no longer considered eukaryotes, they're just goo bouncing around a cell wall
November 3, 2026 at 3:15 PM
Going viral on reddit by claiming I'm a teacher and my students are so remedial they're no longer considered eukaryotes, they're just goo bouncing around a cell wall
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea
#eukaryotes #evolution #archaea #MicroSky #ArchaeSky
@nature.com
www.nature.com/articles/s41...
#eukaryotes #evolution #archaea #MicroSky #ArchaeSky
@nature.com
www.nature.com/articles/s41...
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea - Nature
Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Pro...
www.nature.com
October 31, 2026 at 9:11 AM
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea
#eukaryotes #evolution #archaea #MicroSky #ArchaeSky
@nature.com
www.nature.com/articles/s41...
#eukaryotes #evolution #archaea #MicroSky #ArchaeSky
@nature.com
www.nature.com/articles/s41...
The structural history of Eukarya
#eukaryotes #proteins #StructuralBiology #MicroSky
@science.org
www.science.org/doi/10.1126/...
#eukaryotes #proteins #StructuralBiology #MicroSky
@science.org
www.science.org/doi/10.1126/...
The structural history of Eukarya
Comparative genomics has traditionally relied on sequence-based markers, yet the global evolutionary landscape of protein architecture remains largely unexplored. We present the Structural History of ...
www.science.org
November 2, 2026 at 8:28 AM
The structural history of Eukarya
#eukaryotes #proteins #StructuralBiology #MicroSky
@science.org
www.science.org/doi/10.1126/...
#eukaryotes #proteins #StructuralBiology #MicroSky
@science.org
www.science.org/doi/10.1126/...
I’m pleased to share my second PhD chapter has been published in FEMS Microbiology Ecology!
We investigated microbial eukaryotic diversity across terrestrial, freshwater and coastal marine environments from the Canadian High Arctic, using
18S rRNA gene ONT sequencing.
doi.org/10.1093/fems...
We investigated microbial eukaryotic diversity across terrestrial, freshwater and coastal marine environments from the Canadian High Arctic, using
18S rRNA gene ONT sequencing.
doi.org/10.1093/fems...
Diversity and connectivity of microbial eukaryotes in High Arctic terrestrial and aquatic ecosystems
18S rRNA gene microbial eukaryote community assessment identified distinct connectivity between terrestrial, freshwater, and marine coastal environments in
doi.org
November 4, 2026 at 10:14 PM
I’m pleased to share my second PhD chapter has been published in FEMS Microbiology Ecology!
We investigated microbial eukaryotic diversity across terrestrial, freshwater and coastal marine environments from the Canadian High Arctic, using
18S rRNA gene ONT sequencing.
doi.org/10.1093/fems...
We investigated microbial eukaryotic diversity across terrestrial, freshwater and coastal marine environments from the Canadian High Arctic, using
18S rRNA gene ONT sequencing.
doi.org/10.1093/fems...
Tracing the Evolutionary Histories of Human Cholinergic Proteins Across Eukaryotes: A Comparative Phylogenomic Study https://www.biorxiv.org/content/10.64898/2026.11.04.764462v1
November 6, 2026 at 1:31 PM
Tracing the Evolutionary Histories of Human Cholinergic Proteins Across Eukaryotes: A Comparative Phylogenomic Study https://www.biorxiv.org/content/10.64898/2026.11.04.764462v1
Tracing the Evolutionary Histories of Human Cholinergic Proteins Across Eukaryotes: A Comparative Phylogenomic Study https://www.biorxiv.org/content/10.64898/2026.11.04.764462v1
November 6, 2026 at 1:31 PM
Tracing the Evolutionary Histories of Human Cholinergic Proteins Across Eukaryotes: A Comparative Phylogenomic Study https://www.biorxiv.org/content/10.64898/2026.11.04.764462v1
Our paper on archaea closely related to eukaryotes is officially online in Nature!
This work brings us closer to understanding what our ancient ancestors may have looked like and how they lived when our lineage was still archaeal.
www.nature.com/articles/s41...
1/7
This work brings us closer to understanding what our ancient ancestors may have looked like and how they lived when our lineage was still archaeal.
www.nature.com/articles/s41...
1/7
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea - Nature
Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Pro...
www.nature.com
October 29, 2026 at 1:29 AM
Our paper on archaea closely related to eukaryotes is officially online in Nature!
This work brings us closer to understanding what our ancient ancestors may have looked like and how they lived when our lineage was still archaeal.
www.nature.com/articles/s41...
1/7
This work brings us closer to understanding what our ancient ancestors may have looked like and how they lived when our lineage was still archaeal.
www.nature.com/articles/s41...
1/7
John Archibald presenting on the wild west of genomic and metagenomic studies of microbial Eukaryotes, where new branches of the eTOL are published every 18 months. These species massively understudied while ubiquitous. Diplonemids can be ~20% of OTU's in ocean samples #iBOL2026
November 5, 2026 at 2:13 AM
John Archibald presenting on the wild west of genomic and metagenomic studies of microbial Eukaryotes, where new branches of the eTOL are published every 18 months. These species massively understudied while ubiquitous. Diplonemids can be ~20% of OTU's in ocean samples #iBOL2026
Two new cultured archaea show that the closest relatives of eukaryotes are internally simple, syntrophic, internally simple and live on peptides. They can also breathe oxygen, provided they don't inhale #eukaryogenesis. Paper in @nature.com www.nature.com/articles/s41...
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea - Nature
Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Pro...
www.nature.com
October 28, 2026 at 5:14 PM
Two new cultured archaea show that the closest relatives of eukaryotes are internally simple, syntrophic, internally simple and live on peptides. They can also breathe oxygen, provided they don't inhale #eukaryogenesis. Paper in @nature.com www.nature.com/articles/s41...
Diversity and connectivity of microbial eukaryotes in High Arctic terrestrial and aquatic ecosystems | FEMS Microbiology Ecology | Oxford Academic
Diversity and connectivity of microbial eukaryotes in High Arctic terrestrial and aquatic ecosystems
18S rRNA gene microbial eukaryote community assessment identified distinct connectivity between terrestrial, freshwater, and marine coastal environments in
dx.doi.org
November 1, 2026 at 4:22 AM
Diversity and connectivity of microbial eukaryotes in High Arctic terrestrial and aquatic ecosystems | FEMS Microbiology Ecology | Oxford Academic
November 5, 2026 at 7:36 PM
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea www.nature.com/articles/s41... #jcampubs
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea - Nature
Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Pro...
www.nature.com
October 29, 2026 at 1:44 PM
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea www.nature.com/articles/s41... #jcampubs
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea www.nature.com/articles/s41...
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea - Nature
Cultures reveal conservation of cell structure, physical symbioses and anaerobiosis across Heimdallarchaeia (the archaeal lineage that branches closest to eukaryotes) and other Pro...
www.nature.com
October 29, 2026 at 8:46 PM
Eukaryotes’ closest relatives are internally simple syntrophic peptidotrophic archaea www.nature.com/articles/s41...
It's no astrophage (or taumoeba), but the recently-discovered Cascades fire amoeba (Incendamoeba cascadensis) has set a new record for high temperature survival by a eukaryote. It can live through temps over 70° C (158° F) and reproduce at 63° C (145° F).
Meet the ‘fire amoeba,’ a record-breaking survivor of extreme heat
Incendiamoeba cascadensis can replicate at 145° F, breaking the heat tolerance record for eukaryotes, a domain of life that includes plants and animals.
www.sciencenews.org
November 3, 2026 at 10:11 PM
It's no astrophage (or taumoeba), but the recently-discovered Cascades fire amoeba (Incendamoeba cascadensis) has set a new record for high temperature survival by a eukaryote. It can live through temps over 70° C (158° F) and reproduce at 63° C (145° F).
Carbon-A from Hugging Face (Oct 8): a 1.2B-parameter DNA model that annotates protein-coding genes across eukaryotes. It reads 98,304 bp at nucleotide resolution on both strands and ships a 48K-assembly annotation database. No signup: toolome.bio/tools/carbon-a/ #Genomics #GenomeAnnotation
Carbon-A: license, commercial use, paper — Genomics & DNA models | Toolome
Carbon-A: 1.2B DNA model that annotates protein-coding genes across eukaryotes; ships a 48K-assembly annotation database. Commercial use: Unknown.
toolome.bio
November 2, 2026 at 4:21 AM
Carbon-A from Hugging Face (Oct 8): a 1.2B-parameter DNA model that annotates protein-coding genes across eukaryotes. It reads 98,304 bp at nucleotide resolution on both strands and ships a 48K-assembly annotation database. No signup: toolome.bio/tools/carbon-a/ #Genomics #GenomeAnnotation
Happy to share our preprint with @chaocheng.bsky.social "Single-molecule nascent RNA profiling reveals multiple layers of co-transcriptional splicing and their reprogramming by cold in Arabidopsis"
Thanks to all co-authors!
www.biorxiv.org/content/10.6...
Thanks to all co-authors!
www.biorxiv.org/content/10.6...
Single-molecule nascent RNA profiling reveals multiple layers of co-transcriptional splicing and their reprogramming by cold in Arabidopsis
In eukaryotes, RNA polymerase II (Pol II) transcription is closely coupled to RNA processing, yet how polymerase progression coordinates multiple processing events within individual nascent transcript...
www.biorxiv.org
November 3, 2026 at 2:07 PM
Happy to share our preprint with @chaocheng.bsky.social "Single-molecule nascent RNA profiling reveals multiple layers of co-transcriptional splicing and their reprogramming by cold in Arabidopsis"
Thanks to all co-authors!
www.biorxiv.org/content/10.6...
Thanks to all co-authors!
www.biorxiv.org/content/10.6...
A symbiogenic merger enabled by oxygen initiated the evolution of eukaryotes www.pnas.org/doi/10.1073/... #jcampubs
A symbiogenic merger enabled by oxygen initiated the evolution of eukaryotes | PNAS
Recently, extensive genetic information about archaeal hosts at the basis of eukaryogenesis has come to light. Characterization of these first euka...
www.pnas.org
October 30, 2026 at 3:18 PM
A symbiogenic merger enabled by oxygen initiated the evolution of eukaryotes www.pnas.org/doi/10.1073/... #jcampubs
Daniel also highlights the eukaryotic proteins and their Asgard archaeal homologues
See their @natmicrobiol.nature.com
www.nature.com/articles/s41...
#KNVMfall2026
See their @natmicrobiol.nature.com
www.nature.com/articles/s41...
#KNVMfall2026
Prediction of eukaryotic cellular complexity in Asgard archaea using structural modelling - Nature Microbiology
A structural catalogue of the Asgard archaeal pangenome reveals hundreds of eukaryotic-like proteins that suggest a higher degree of cellular complexity in the archaeal ancestor of eukaryotes.
www.nature.com
November 6, 2026 at 10:39 AM
Daniel also highlights the eukaryotic proteins and their Asgard archaeal homologues
See their @natmicrobiol.nature.com
www.nature.com/articles/s41...
#KNVMfall2026
See their @natmicrobiol.nature.com
www.nature.com/articles/s41...
#KNVMfall2026
Paper: Eukaryotes' closest relatives are internally simple syntrophic peptidotrophic archaea. Imachi, ..., Takai. Nature (2026). https://doi.org/10.1038/s41586-026-11170-7
Scored on Frontier: https://frontierresearch.co/breakthroughs/W4407955686
Scored on Frontier: https://frontierresearch.co/breakthroughs/W4407955686
November 4, 2026 at 6:30 PM
Paper: Eukaryotes' closest relatives are internally simple syntrophic peptidotrophic archaea. Imachi, ..., Takai. Nature (2026). https://doi.org/10.1038/s41586-026-11170-7
Scored on Frontier: https://frontierresearch.co/breakthroughs/W4407955686
Scored on Frontier: https://frontierresearch.co/breakthroughs/W4407955686
Yeah, I just love it when learning so many cool things from a paper:
Why are archaea not pathogenic? A hypothesis based on metabolism-habitat covariation | mBio journals.asm.org/doi/10.1128/...
Why are archaea not pathogenic? A hypothesis based on metabolism-habitat covariation | mBio journals.asm.org/doi/10.1128/...
Why are archaea not pathogenic? A hypothesis based on metabolism-habitat covariation | mBio
Pathogenicity—the ability to cause infectious disease—is widespread among bacteria
and eukaryotes but conspicuously absent from archaea, the third domain of life. To
understand why archaea are non-pat...
journals.asm.org
November 5, 2026 at 10:18 PM
Yeah, I just love it when learning so many cool things from a paper:
Why are archaea not pathogenic? A hypothesis based on metabolism-habitat covariation | mBio journals.asm.org/doi/10.1128/...
Why are archaea not pathogenic? A hypothesis based on metabolism-habitat covariation | mBio journals.asm.org/doi/10.1128/...