THE PAN-GO #FUNCTIONOME IS LIVE! Read our brand new #openaccess @nature.com paper and explore the PAN-GO Functionome, our most accurate and complete resource ever!
Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343
Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343
February 26, 2025 at 9:50 PM
THE PAN-GO #FUNCTIONOME IS LIVE! Read our brand new #openaccess @nature.com paper and explore the PAN-GO Functionome, our most accurate and complete resource ever!
Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343
Paper links, press release, how to contribute and more on the @alliancegenome.bsky.social Forums: community.alliancegenome.org/t/8343
Nature research paper: A compendium of human gene functions derived from evolutionary modelling
https://go.nature.com/4gXxIRg
https://go.nature.com/4gXxIRg
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
go.nature.com
February 26, 2025 at 4:53 PM
Nature research paper: A compendium of human gene functions derived from evolutionary modelling
https://go.nature.com/4gXxIRg
https://go.nature.com/4gXxIRg
The PAN-GO #Functionome was announced last week in @nature.com-but do you know how to use it?
Here's how to find functions for a selected human #gene:
➡️ community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome:
💡 community.alliancegenome.org/t/8343
🧪🧬 #science #research #human
Here's how to find functions for a selected human #gene:
➡️ community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome:
💡 community.alliancegenome.org/t/8343
🧪🧬 #science #research #human
March 3, 2025 at 11:47 PM
The PAN-GO #Functionome was announced last week in @nature.com-but do you know how to use it?
Here's how to find functions for a selected human #gene:
➡️ community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome:
💡 community.alliancegenome.org/t/8343
🧪🧬 #science #research #human
Here's how to find functions for a selected human #gene:
➡️ community.alliancegenome.org/t/8353
ICYMI, more on the PAN-GO Functionome:
💡 community.alliancegenome.org/t/8343
🧪🧬 #science #research #human
As a final nod to 2025, #GeneOntology announces our latest paper in @narjournal.bsky.social! Updates include expanded #Ontology & annotations in #Metabolism, multi-org interactions, #chromatin remodeling, & more.
Also ft. #Functionome v2 and 1500+ GO-CAM pathway models! 🧬🧪
doi.org/10.1093/nar/...
Also ft. #Functionome v2 and 1500+ GO-CAM pathway models! 🧬🧪
doi.org/10.1093/nar/...
The Gene Ontology knowledgebase in 2026
Abstract. The Gene Ontology (GO) knowledgebase (https://geneontology.org) is a comprehensive resource describing the functions of genes. The GO knowledgeba
doi.org
December 19, 2025 at 11:41 PM
As a final nod to 2025, #GeneOntology announces our latest paper in @narjournal.bsky.social! Updates include expanded #Ontology & annotations in #Metabolism, multi-org interactions, #chromatin remodeling, & more.
Also ft. #Functionome v2 and 1500+ GO-CAM pathway models! 🧬🧪
doi.org/10.1093/nar/...
Also ft. #Functionome v2 and 1500+ GO-CAM pathway models! 🧬🧪
doi.org/10.1093/nar/...
I have several scientific pet peeves: Comic sans in presentations, "statistically significant" differences that aren't substantially different, and GO terms. They can be misleading and are often so broad as to be meaningless.
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 27, 2025 at 11:56 PM
I have several scientific pet peeves: Comic sans in presentations, "statistically significant" differences that aren't substantially different, and GO terms. They can be misleading and are often so broad as to be meaningless.
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
GO Team: Hold my beer. GO big or GO home.
www.nature.com/articles/s41...
You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories
community.alliancegenome.org/t/8362
🧬🧪 #GOSlims
ICYMI: community.alliancegenome.org/t/8343
community.alliancegenome.org/t/8362
🧬🧪 #GOSlims
ICYMI: community.alliancegenome.org/t/8343
March 12, 2025 at 11:17 PM
You know about the PAN-GO #Functionome, but have you explored the power of the Functional Category search? Learn how to find #humangenes of interest in just a few clicks, using the Functional Categories
community.alliancegenome.org/t/8362
🧬🧪 #GOSlims
ICYMI: community.alliancegenome.org/t/8343
community.alliancegenome.org/t/8362
🧬🧪 #GOSlims
ICYMI: community.alliancegenome.org/t/8343
A compendium of human gene functions derived from evolutionary modelling @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 26, 2025 at 7:59 PM
A compendium of human gene functions derived from evolutionary modelling @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Muñoz-Mérida & Muñoz-Pajares introduce the concept of the pan-functionome — the full set of protein functions encoded by the proteome of individuals belonging to a taxonomic group — and explore its evolutionary implications.
🔗 doi.org/10.1093/molbev/msag121
#evobio #molbio
🔗 doi.org/10.1093/molbev/msag121
#evobio #molbio
June 5, 2026 at 10:02 AM
Muñoz-Mérida & Muñoz-Pajares introduce the concept of the pan-functionome — the full set of protein functions encoded by the proteome of individuals belonging to a taxonomic group — and explore its evolutionary implications.
🔗 doi.org/10.1093/molbev/msag121
#evobio #molbio
🔗 doi.org/10.1093/molbev/msag121
#evobio #molbio
'For human genes with roles in immune system processes, we observed a peak before the vertebrate LCA and a long tail through to the placental mammal LCA, which reflects the evolutionary appearance and further elaboration of the adaptive immune system.'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
March 4, 2025 at 4:05 PM
'For human genes with roles in immune system processes, we observed a peak before the vertebrate LCA and a long tail through to the placental mammal LCA, which reflects the evolutionary appearance and further elaboration of the adaptive immune system.'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A large-scale effort integrating evolutionary modeling and experimental data has mapped 68,667 gene functions, covering ~82% of human protein-coding genes. This resource enhances Gene Ontology analyses and the evolutionary origins of molecular functions, improving biomedical and genomic research:
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
March 3, 2025 at 9:52 PM
A large-scale effort integrating evolutionary modeling and experimental data has mapped 68,667 gene functions, covering ~82% of human protein-coding genes. This resource enhances Gene Ontology analyses and the evolutionary origins of molecular functions, improving biomedical and genomic research:
The Gene Ontology Consortium has launched a comprehensive online resource detailing the functions of over 20,000 human genes, integrating evolutionary data for enhanced accuracy.
Unveiling the 'functionome': Online resource describes functions of more than 20,000 human genes
A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website.
medicalxpress.com
February 26, 2025 at 4:02 PM
The Gene Ontology Consortium has launched a comprehensive online resource detailing the functions of over 20,000 human genes, integrating evolutionary data for enhanced accuracy.
Using evolutionary modeling, the Gene Ontology Consortium has assembled a searchable compendium of gene functions for 82% of human genes.
www.nature.com/articles/s41...
functionome.geneontology.org
www.nature.com/articles/s41...
functionome.geneontology.org
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 26, 2025 at 4:50 PM
Using evolutionary modeling, the Gene Ontology Consortium has assembled a searchable compendium of gene functions for 82% of human genes.
www.nature.com/articles/s41...
functionome.geneontology.org
www.nature.com/articles/s41...
functionome.geneontology.org
The Gene Ontology Consortium has unveiled a new resource detailing the known functions of all protein-coding human genes. This comprehensive encyclopedia represents a significant advancement in understanding gene functions across species.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
March 5, 2025 at 4:01 PM
The Gene Ontology Consortium has unveiled a new resource detailing the known functions of all protein-coding human genes. This comprehensive encyclopedia represents a significant advancement in understanding gene functions across species.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Even a tiny weed can have impacts on human health. Excellent new paper from the Gene Ontology Consortium describing a compendium of human gene function that used experimental annotations from many model organisms including Arabidopsis.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 26, 2025 at 8:23 PM
Even a tiny weed can have impacts on human health. Excellent new paper from the Gene Ontology Consortium describing a compendium of human gene function that used experimental annotations from many model organisms including Arabidopsis.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
“A new Gene Ontology resource integrates evolutionary data to map human gene functions, aiding biomedical research.“
[Scientists Create Most Complete Human Gene Function Database | Technology Networks]
www.technologynetworks.com/genomics/new...
[Scientists Create Most Complete Human Gene Function Database | Technology Networks]
www.technologynetworks.com/genomics/new...
Scientists Create Most Complete Human Gene Function Database
The Gene Ontology Consortium has released a new resource mapping human gene functions using evolutionary modeling. The PAN-GO functionome integrates experimental data from humans and model organisms, ...
www.technologynetworks.com
February 28, 2025 at 9:53 PM
“A new Gene Ontology resource integrates evolutionary data to map human gene functions, aiding biomedical research.“
[Scientists Create Most Complete Human Gene Function Database | Technology Networks]
www.technologynetworks.com/genomics/new...
[Scientists Create Most Complete Human Gene Function Database | Technology Networks]
www.technologynetworks.com/genomics/new...
Unveiling the #functionome': Online resource describes functions of more than 20,000 #human #genes.
#jargonomics #Gene_Ontology #evolutionary #modelling
medicalxpress.com/news/2025-02...
#jargonomics #Gene_Ontology #evolutionary #modelling
medicalxpress.com/news/2025-02...
Unveiling the 'functionome': Online resource describes functions of more than 20,000 human genes
A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first...
medicalxpress.com
February 26, 2025 at 5:04 PM
Unveiling the #functionome': Online resource describes functions of more than 20,000 #human #genes.
#jargonomics #Gene_Ontology #evolutionary #modelling
medicalxpress.com/news/2025-02...
#jargonomics #Gene_Ontology #evolutionary #modelling
medicalxpress.com/news/2025-02...
Our new paper
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
February 26, 2025 at 6:09 PM
Our new paper
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multiple advancements distinguish this functionome from those published previously and from previously available annotations in the GO knowledgebase. Coverage of human genes is greater, with 82% of genes associated with at least one functional characteristic. www.nature.com/articles/s41...
A compendium of human gene functions derived from evolutionary modelling - Nature
Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.
www.nature.com
April 15, 2025 at 2:41 PM
Multiple advancements distinguish this functionome from those published previously and from previously available annotations in the GO knowledgebase. Coverage of human genes is greater, with 82% of genes associated with at least one functional characteristic. www.nature.com/articles/s41...
#bmcgenomics "functionome"??? :D http://www.biomedcentral.com/1471-2164/13/699
Evaluation method for the potential functionome harbored ...
Background One of the main goals of genomic analysis is t...
www.biomedcentral.com
February 19, 2025 at 8:38 PM
#bmcgenomics "functionome"??? :D http://www.biomedcentral.com/1471-2164/13/699
Discover the newly launched PAN-GO functionome: a comprehensive, evolutionary-based encyclopedia detailing the functions of over 20,000 human genes.
Revolutionizing Genomics: A New Evolutionary Approach to Human Gene Functions
Discover the newly launched PAN-GO functionome: a comprehensive, evolutionary-based encyclopedia detailing the functions of over 20,000 human genes.
www.science-tldr.com
February 27, 2025 at 12:15 PM
Discover the newly launched PAN-GO functionome: a comprehensive, evolutionary-based encyclopedia detailing the functions of over 20,000 human genes.
