#glycoproteinB
Why are some HCMV glycoprotein B variants much more fusogenic than others?

Check out our new #mBio paper with the Marco Thomas lab, where we identify structural determinants regulating gH/gL-independent fusion across gB variants.
journals.asm.org/doi/10.1128/...
#hcmv #glycoproteinB #fusion
Functional dissection of HCMV gB’s autonomous fusion activity provides insights into how polymorphisms in clinical isolates confer distinct characteristics | mBio
Human cytomegalovirus (HCMV) establishes lifelong, predominantly asymptomatic infections but remains a major cause of morbidity and mortality in immunocompromised individuals and newborns. This study ...
journals.asm.org
July 18, 2026 at 5:43 AM