August 10, 2026 at 12:34 AM
Visit the table of all #GWAS with #Metabolomics to read more about the latest #mQTL discoveries (updated 23 April 2024) wp.me/p6NCOp-2y
A Table of all published GWAS with metabolomics
Here you find references to all published mGWAS in humans, ordered by publication date. If a study is missing from this list, please let me know. Please note that I do not apply a strict inclusion …
wp.me
December 2, 2024 at 1:39 PM
Visit the table of all #GWAS with #Metabolomics to read more about the latest #mQTL discoveries (updated 23 April 2024) wp.me/p6NCOp-2y
One of those truly multiomic studies. Get to see sQTL, eQTL, pQTL, mQTL connect genetic etiology across molecular traits and health outcomes
📣 New from the lab: The contribution of genetic determinants of blood gene expression and splicing to molecular phenotypes and health outcomes www.nature.com/articles/s41...
Check out the INTERVAL RNAseq portal www.intervalrna.org.uk
Led by @alextokolyi.bsky.social & Elodie Persyn!
Check out the INTERVAL RNAseq portal www.intervalrna.org.uk
Led by @alextokolyi.bsky.social & Elodie Persyn!
March 5, 2025 at 6:15 AM
One of those truly multiomic studies. Get to see sQTL, eQTL, pQTL, mQTL connect genetic etiology across molecular traits and health outcomes
Read more about it here: https://mrf.lu/MQtL
May 28, 2026 at 4:45 PM
Read more about it here: https://mrf.lu/MQtL
🌀 Alfredo Graça avança a previsão do tempo para a Páscoa: “um jato polar ondulante poderá trazer tempestades a Portugal".
🗞️ Confira a previsão com @alfredometeograca.bsky.social: https://shre.ink/MqTL
🗞️ Confira a previsão com @alfredometeograca.bsky.social: https://shre.ink/MqTL
April 2, 2025 at 10:51 AM
🌀 Alfredo Graça avança a previsão do tempo para a Páscoa: “um jato polar ondulante poderá trazer tempestades a Portugal".
🗞️ Confira a previsão com @alfredometeograca.bsky.social: https://shre.ink/MqTL
🗞️ Confira a previsão com @alfredometeograca.bsky.social: https://shre.ink/MqTL
DNA methylation study: 7619 Han Chinese reveal 331,048 mCpGs, 28,978 novel. Strong EUR-EAS overlap, plus unique EAS mQTLs. Genetic diversity insights. PMID:41672998, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-69372-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Genetic regulation of methylation across East Asian and European populations | Nature Communications
Methylation quantitative trait loci (mQTL) studies have predominantly focused on European populations (EUR), limiting understanding of the genetic regulation of DNA methylation in other populations. We conduct an East Asian (EAS) mQTL analysis, integrating data from three independent samples comprising 7619 Han Chinese individuals. We identified 331,048 mCpGs, including 28,978 novel mCpGs in EAS. While observing substantial sharing of mQTL between EUR and EAS, we also identify EAS-specific mQTLs, often driven by variants with low minor allele frequencies in EUR. We found that mQTLs enriched for disease and trait heritability, especially for matched-ancestry mQTLs, underscoring their utility for interpreting GWAS results and highlighting the role of DNA methylation in diseases. Our EAS mQTL resource provides valuable insights into the genetic architecture of DNA methylation and its contribution to complex traits. Here the authors identify via an East Asian mQTL study (n = 7,619) nearly
doi.org
March 4, 2026 at 6:10 AM
مقتل جندي إسرائيلي برفقة 4 مصابين بصاروخ مضاد للدروع جنوب لبنان.. والجيش الإسرائيلي يعترف: "الكتيبة 77" دخلت كمين محكمhttps://sexarabnar.com/threads/mqtl-jndy-srayyly-brfqh-4-msabyn-bsarwkh-mdad-lldrw-jnwb-lbnan-waljysh-lasrayyly-ytrf-lktybh-77-dkhlt-kmyn-mhkm.29199/
March 26, 2026 at 8:59 PM
مقتل جندي إسرائيلي برفقة 4 مصابين بصاروخ مضاد للدروع جنوب لبنان.. والجيش الإسرائيلي يعترف: "الكتيبة 77" دخلت كمين محكمhttps://sexarabnar.com/threads/mqtl-jndy-srayyly-brfqh-4-msabyn-bsarwkh-mdad-lldrw-jnwb-lbnan-waljysh-lasrayyly-ytrf-lktybh-77-dkhlt-kmyn-mhkm.29199/
METHODS: We curated 181 EDCs and identified 1,116 EDC-related genes through chemical-gene interaction network analysis, followed by integration of multi-omics quantitative trait loci datasets (eQTL, sQTL, mQTL, and pQTL) to derive genetic instruments. (🧵 4/14)
June 9, 2026 at 10:51 AM
METHODS: We curated 181 EDCs and identified 1,116 EDC-related genes through chemical-gene interaction network analysis, followed by integration of multi-omics quantitative trait loci datasets (eQTL, sQTL, mQTL, and pQTL) to derive genetic instruments. (🧵 4/14)
youtube.com/watch?v=mQTl.... Horrible news for the US TREASURY! Great for CHINA
Bessent Orders Major Global Bank To Cancel All China Loans As U.S. Financial Panic Begins
YouTube video by Sean Foo
youtube.com
April 28, 2025 at 1:57 PM
youtube.com/watch?v=mQTl.... Horrible news for the US TREASURY! Great for CHINA
We further found that many mQTL effects are shared across biofluids. This indicates that at least some genetic effects on the metabolome are not specific to biofluid or tissue type, as also observed in gene expression QTL studies.
March 6, 2025 at 1:11 PM
We further found that many mQTL effects are shared across biofluids. This indicates that at least some genetic effects on the metabolome are not specific to biofluid or tissue type, as also observed in gene expression QTL studies.
bluesky channel comment Quo totam at eveniet natus https://mrf.lu/mqTL
March 5, 2026 at 12:16 AM
bluesky channel comment Quo totam at eveniet natus https://mrf.lu/mqTL
Data source: UK biobank
She looked at warfarin and statins and looked at instrumental variable analysis
mQTL analysis
Estimate a causal effect (DNA methylation) & drug response
Then, they do several steps to do quality control
Relevance assumption, exclusivity assumption, independence assumption
She looked at warfarin and statins and looked at instrumental variable analysis
mQTL analysis
Estimate a causal effect (DNA methylation) & drug response
Then, they do several steps to do quality control
Relevance assumption, exclusivity assumption, independence assumption
January 6, 2025 at 9:03 PM
Data source: UK biobank
She looked at warfarin and statins and looked at instrumental variable analysis
mQTL analysis
Estimate a causal effect (DNA methylation) & drug response
Then, they do several steps to do quality control
Relevance assumption, exclusivity assumption, independence assumption
She looked at warfarin and statins and looked at instrumental variable analysis
mQTL analysis
Estimate a causal effect (DNA methylation) & drug response
Then, they do several steps to do quality control
Relevance assumption, exclusivity assumption, independence assumption
NEW DATASET!
Researchers used SomaScan and Metabalon to measure metabolite and protein levels in 3,000 participants of Caucasian and African ancestries.
dss.niagads.org/datasets/ng...
Researchers used SomaScan and Metabalon to measure metabolite and protein levels in 3,000 participants of Caucasian and African ancestries.
dss.niagads.org/datasets/ng...
NG00180 - Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups - DSS NIAGADS
All data provided in this dataset are open access and are available publicly in the “Open Access Dataset” tab.
dss.niagads.org
January 27, 2026 at 5:00 PM
NEW DATASET!
Researchers used SomaScan and Metabalon to measure metabolite and protein levels in 3,000 participants of Caucasian and African ancestries.
dss.niagads.org/datasets/ng...
Researchers used SomaScan and Metabalon to measure metabolite and protein levels in 3,000 participants of Caucasian and African ancestries.
dss.niagads.org/datasets/ng...
NEW DATASET!
Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups. #genomics #alzresearch
dss.niagads.org/datasets/ng...
Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups. #genomics #alzresearch
dss.niagads.org/datasets/ng...
NG00180 - Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups - DSS NIAGADS
All data provided in this dataset are open access and are available publicly in the “Open Access Dataset” tab.
dss.niagads.org
October 6, 2025 at 4:00 PM
NEW DATASET!
Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups. #genomics #alzresearch
dss.niagads.org/datasets/ng...
Four large scale pQTL and mQTL atlases in plasma from European and African ancestral groups. #genomics #alzresearch
dss.niagads.org/datasets/ng...
본 연구는 통합적 다중 오믹스 및 인과 추론 프레임워크를 활용하여 편두통 위험에 기여하는 EDC 관련 유전자를 규명하고 그 기전을 규명하는 것을 목표로 한다.
방법: 우리는 181개의 EDC를 선별하고 화학-유전자 상호작용 네트워크 분석을 통해 1,116개의 EDC 관련 유전자를 확인한 후, 다중 오믹스 정량형 형질 좌위(eQTL, sQTL, mQTL 및 pQTL) 데이터셋을 통합하여 유전적 도구를 도출했다. (🧵 2/7)
방법: 우리는 181개의 EDC를 선별하고 화학-유전자 상호작용 네트워크 분석을 통해 1,116개의 EDC 관련 유전자를 확인한 후, 다중 오믹스 정량형 형질 좌위(eQTL, sQTL, mQTL 및 pQTL) 데이터셋을 통합하여 유전적 도구를 도출했다. (🧵 2/7)
June 9, 2026 at 10:57 AM
본 연구는 통합적 다중 오믹스 및 인과 추론 프레임워크를 활용하여 편두통 위험에 기여하는 EDC 관련 유전자를 규명하고 그 기전을 규명하는 것을 목표로 한다.
방법: 우리는 181개의 EDC를 선별하고 화학-유전자 상호작용 네트워크 분석을 통해 1,116개의 EDC 관련 유전자를 확인한 후, 다중 오믹스 정량형 형질 좌위(eQTL, sQTL, mQTL 및 pQTL) 데이터셋을 통합하여 유전적 도구를 도출했다. (🧵 2/7)
방법: 우리는 181개의 EDC를 선별하고 화학-유전자 상호작용 네트워크 분석을 통해 1,116개의 EDC 관련 유전자를 확인한 후, 다중 오믹스 정량형 형질 좌위(eQTL, sQTL, mQTL 및 pQTL) 데이터셋을 통합하여 유전적 도구를 도출했다. (🧵 2/7)
#eshg2025 Jensen: Alu insertion in ACE gene tags lead Alz GWAS hit. For Parkinson's colocalise BIN3 insertion associated with variable methylation - an mQTL driving a GWAS hit. Nice use of @nanoporetech.com data.
May 25, 2025 at 9:57 AM
#eshg2025 Jensen: Alu insertion in ACE gene tags lead Alz GWAS hit. For Parkinson's colocalise BIN3 insertion associated with variable methylation - an mQTL driving a GWAS hit. Nice use of @nanoporetech.com data.
This research letter integrates #MultiOmics & #MendelianRandomization analyses to identify #PANoptosis genes #BCL2L1 and UBC as key regulators of #MyocardialInfarction (MI) via #DNAMethylation, revealing BCL2L1 as a promising therapeutic target for MI intervention.
#OpenAccess: tinyurl.com/2yxas89v
#OpenAccess: tinyurl.com/2yxas89v
Potential Therapeutic Targets of PANoptosis for Myocardial Infarction: A Summary-Data-Based Mendelian Randomization Study Integrating eQTL, mQTL, and Multi-GWAS Data
This study explores PANoptosis as a therapeutic target for myocardial infarction using Mendelian randomization and multi-omics data analysis.
tinyurl.com
November 6, 2025 at 12:32 PM
This research letter integrates #MultiOmics & #MendelianRandomization analyses to identify #PANoptosis genes #BCL2L1 and UBC as key regulators of #MyocardialInfarction (MI) via #DNAMethylation, revealing BCL2L1 as a promising therapeutic target for MI intervention.
#OpenAccess: tinyurl.com/2yxas89v
#OpenAccess: tinyurl.com/2yxas89v
This study explores PANoptosis as a therapeutic target for #myocardialinfarction using #Mendelianrandomization and multi-omics data analysis.
Read More: cvia-journal.org/myocardial-i...
#PANoptosis #Genomics #HeartHealth #mQTL #GWAS #CVIAJournal #Cardiology #CardioEd @scienceopen.bsky.social
Read More: cvia-journal.org/myocardial-i...
#PANoptosis #Genomics #HeartHealth #mQTL #GWAS #CVIAJournal #Cardiology #CardioEd @scienceopen.bsky.social
Potential Therapeutic Targets of PANoptosis for Myocardial Infarction: A Summary-Data-Based Mendelian Randomization Study Integrating eQTL, mQTL, and Multi-GWAS Data
This study explores PANoptosis as a therapeutic target for myocardial infarction using Mendelian randomization and multi-omics data analysis.
cvia-journal.org
March 14, 2025 at 11:53 AM
This study explores PANoptosis as a therapeutic target for #myocardialinfarction using #Mendelianrandomization and multi-omics data analysis.
Read More: cvia-journal.org/myocardial-i...
#PANoptosis #Genomics #HeartHealth #mQTL #GWAS #CVIAJournal #Cardiology #CardioEd @scienceopen.bsky.social
Read More: cvia-journal.org/myocardial-i...
#PANoptosis #Genomics #HeartHealth #mQTL #GWAS #CVIAJournal #Cardiology #CardioEd @scienceopen.bsky.social
https://youtu.be/8YehoejPll8?si=XnQ6aV06I4V-MQtl
La meva #CançóDelDia per al dissabte 20 de desembre és aquesta de la #RosalieCunningham #SouthendOnSea #veu #guitarra #teclats #pop #folk #psychrock #progrock 🎊!
La meva #CançóDelDia per al dissabte 20 de desembre és aquesta de la #RosalieCunningham #SouthendOnSea #veu #guitarra #teclats #pop #folk #psychrock #progrock 🎊!
December 16, 2025 at 3:10 PM
https://youtu.be/8YehoejPll8?si=XnQ6aV06I4V-MQtl
La meva #CançóDelDia per al dissabte 20 de desembre és aquesta de la #RosalieCunningham #SouthendOnSea #veu #guitarra #teclats #pop #folk #psychrock #progrock 🎊!
La meva #CançóDelDia per al dissabte 20 de desembre és aquesta de la #RosalieCunningham #SouthendOnSea #veu #guitarra #teclats #pop #folk #psychrock #progrock 🎊!
Listen to "مقتل جيسيكا ستار ولغز اللمبة المفكوكة" by ليلة الجريمة via #spreaker www.spreaker.com/episode/mqtl...
مقتل جيسيكا ستار ولغز اللمبة المفكوكة - ليلة الجريمة
www.spreaker.com
March 24, 2026 at 2:07 AM
Listen to "مقتل جيسيكا ستار ولغز اللمبة المفكوكة" by ليلة الجريمة via #spreaker www.spreaker.com/episode/mqtl...
Kattoremontien tellingit kulkevat ikkunan vieressä (tietenkin) ja niin myös hissit. Tänään aamulla Teammsikin heräsi hissin ääniin:
Ja kuulostihan se vähän Pan Sonicilta (eli Panasonicillta meille vanhoille faneille): www.youtube.com/watch?v=MQtL...
Ja kuulostihan se vähän Pan Sonicilta (eli Panasonicillta meille vanhoille faneille): www.youtube.com/watch?v=MQtL...
August 15, 2025 at 11:38 AM
Kattoremontien tellingit kulkevat ikkunan vieressä (tietenkin) ja niin myös hissit. Tänään aamulla Teammsikin heräsi hissin ääniin:
Ja kuulostihan se vähän Pan Sonicilta (eli Panasonicillta meille vanhoille faneille): www.youtube.com/watch?v=MQtL...
Ja kuulostihan se vähän Pan Sonicilta (eli Panasonicillta meille vanhoille faneille): www.youtube.com/watch?v=MQtL...
