#mTORpathway
This review outlines recent progress in treating #DiabeticNephropathy via drugs and molecules targeting the #mTORpathway, offering insights for improved prevention and therapy. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...
November 10, 2025 at 4:15 PM
Our findings suggest that everolimus is a promising precision therapy for NPRL2- and NPRL3-related epilepsy, with the potential to reduce seizure frequency, thereby improving patient quality of life.
doi.org/10.1111/epi....

#epilepsy #Epilepsia #ILAE #everolimus #GATOR1complex #mTORpathway
July 30, 2025 at 5:25 PM
Explore the structural and mechanistic basis of the the PI3K/AKT/mTORpathway in this latest review from #biochemj #mTOR #AKT #PI3K #CancerBiology https://doi.org/10.1042/BCJ20253108
March 24, 2026 at 11:00 AM
Key point: Analysis of cortical samples from HMG patients reveals abnormal development of Pvalb interneurons, which acquire cytomegalic features.
doi.org/10.1111/epi....

#epilepsy #ILAE #corticaldevelopmentaldisorders #interneurons #mTORpathway #neocortex
February 27, 2025 at 5:21 PM
This review explores the #mTORpathway structure and its molecular regulation, highlighting the therapeutic potential of targeting mTOR in #ClinicalTrials and its critical interplay with mitochondrial function. @univparissaclay.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...
January 9, 2026 at 6:00 PM
This bibliometric analysis discusses mTOR signaling-associated pathological mechanisms in various renal cell types within a #diabetic environment & highlights the therapeutic implications of targeting the #mTORpathway in #DiabeticNephropathy. #medsky

#OpenAccess: www.sciencedirect.co...
February 25, 2025 at 11:00 PM
New therapeutic targets are urgently needed to improve outcomes in #GastricCancer.

This study identifies the #CREB1–LOC100270746–DDX5 axis as a driver of tumor progression and a promising therapeutic target. #mTORpathway

#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
August 23, 2026 at 5:01 PM