Marine carbon capture and storage company Gigablue has been told it can not proceed with a massive ocean trial of its product in New Zealand. Gigablue's mCDR product is based on Microalgae Carbon Fixation and Sinking (MCFS), in which tiny photosynthetic phytoplankton use sunlight to turn CO2 into organic matter that is then expected to sink as “marine snow” (dead organisms, fecal pellets) to be sequestered in the deep sea for centuries. 

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Professional finance, tax, insurance, and estate services for Wellsville and surrounding communities From MCFS, At Maple City Financial Services, we believe financial planning is about more than investments, it’s about […]

A new analysis by the Monash Centre for Financial Studies (MCFS) highlights the fragility of retirement outcomes for Australians. Australia’s [...]

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Some people with Long COVID and the providers who were treating them wondered if nicotine, delivered by a mechanism other than cigarettes, might help with the chronic disease. For the next several yea...

Limited research on transcription termination and a few terminators hinder the efficient construction of microbial cell factories (MCFs). This study develops a pipeline to predict strong genome-wide terminators using RNA-seq data and an insulated dual-reporter system (IDRS) for quantification, offering integrated tools for precise transcription regulation in MCFs.

Mineralized collagen fibrils (MCFs) are the fundamental building blocks of bone, determining its mechanical properties. Aging and disuse are known to impair bone mechanics, but their specific effects on the nanoscale, in situ mechanical behavior of MCFs remain poorly understood. The present study utilized a murine model involving adult and aged mice, with a subset from each age group subjected to disuse through hindlimb unloading (n = 6). To investigate the in situ nanomechanical response of bone, murine tibiae were tensile-loaded within a custom-made axial loading device while being simultaneously scanned with atomic force microscopy (AFM). The bone surface was partially demineralized to expose the collagen fibrils. High-resolution AFM imaging in tapping-mode was then employed to quantitatively assess the morphological changes and nanomechanical properties of MCFs throughout the bone’s elastic deformation process. In the adult murine tibia, the initial response to load was characterized by fibril reorientation and an increase in the in situ elastic modulus of MCFs, indicating stretching. It was followed by a sliding phase between adjacent fibrils. In contrast, the aged bone exhibited fibril sliding at the onset of loading, accompanied by a gradual decrease in the elastic modulus of MCFs. The nanomechanical alterations induced by disuse were more pronounced in aged mice compared to adults. The present findings demonstrate that aging and disuse significantly alter the nanoscale deformation mechanisms of bone, shifting the response from fibril stretching to predominant sliding. It provides novel evidence for a unique, age-dependent deformation mechanism at the fibrillar level, enhancing the current understanding of how aging and disuse impair bone quality and mechanics.

The Puro.earth Advisory Board has greenlighted the methodology for Microalgae Carbon Fixation and Sinking (MCFS).