Applying a minimally invasive microdialysis system, researchers capture nuanced patterns in aldosterone levels over 24 hours in patients with primary aldosteronism, which could inform timelier diagnostic strategies.
Learn more in #ScienceTranslationalMedicine: https://scim.ag/4xZGMOm
Learn more in #ScienceTranslationalMedicine: https://scim.ag/4xZGMOm
Tissue corticosteroid rhythms are dysregulated predominantly during sleep in primary aldosteronism
Ambulatory 24-hour microdialysis reveals disrupted corticosteroid rhythms in primary aldosteronism.
scim.ag
August 31, 2026 at 6:00 PM
Applying a minimally invasive microdialysis system, researchers capture nuanced patterns in aldosterone levels over 24 hours in patients with primary aldosteronism, which could inform timelier diagnostic strategies.
Learn more in #ScienceTranslationalMedicine: https://scim.ag/4xZGMOm
Learn more in #ScienceTranslationalMedicine: https://scim.ag/4xZGMOm
We have simulated root exudation with microdialysis to stimulate soil microbes.Lots of method optimization & hard work from all coauthors has gone into this, pushed over the finish line by Andreas Schneider. Really happy to see this published looking forward to what’s next! doi.org/10.1186/s128...
Reverse microdialysis of sucrose stimulates soil fungal and bacterial growth at the microscale - BMC Microbiology
Background The rhizosphere is a critical microenvironment that plays key roles in plant nutrient availability, largely due to root interactions with rhizospheric microbes. However, we lack suitable me...
doi.org
August 13, 2025 at 8:07 AM
We have simulated root exudation with microdialysis to stimulate soil microbes.Lots of method optimization & hard work from all coauthors has gone into this, pushed over the finish line by Andreas Schneider. Really happy to see this published looking forward to what’s next! doi.org/10.1186/s128...
So great to be at the #Rhizosphere6
If curious about root exudation effects on nitrogen availability check out Anne Braunroth’s poster #117 today!
#microdialysis #boreal #soil
If curious about root exudation effects on nitrogen availability check out Anne Braunroth’s poster #117 today!
#microdialysis #boreal #soil
June 16, 2025 at 3:53 PM
So great to be at the #Rhizosphere6
If curious about root exudation effects on nitrogen availability check out Anne Braunroth’s poster #117 today!
#microdialysis #boreal #soil
If curious about root exudation effects on nitrogen availability check out Anne Braunroth’s poster #117 today!
#microdialysis #boreal #soil
#new_paper: Membranes for microdialysis of clinical samples
@elsevierconnect.bsky.social: Capillary electrophoresis, Dialysis, Fouling, Membrane, Serum, Ultrafiltration
doi.org/10.1016/j.se...
@elsevierconnect.bsky.social: Capillary electrophoresis, Dialysis, Fouling, Membrane, Serum, Ultrafiltration
doi.org/10.1016/j.se...
September 5, 2025 at 7:38 AM
#new_paper: Membranes for microdialysis of clinical samples
@elsevierconnect.bsky.social: Capillary electrophoresis, Dialysis, Fouling, Membrane, Serum, Ultrafiltration
doi.org/10.1016/j.se...
@elsevierconnect.bsky.social: Capillary electrophoresis, Dialysis, Fouling, Membrane, Serum, Ultrafiltration
doi.org/10.1016/j.se...
🧪🌾PAPER - How to investigate interactions between root exudation and soil microbial community composition? 🧫
The group of @rootsofthenorth.bsky.social and collaborators showed now that microdialysis is a suitable tool to simulate exudation.
Read more in BMC Microbiology:
doi.org/10.1186/s128...
The group of @rootsofthenorth.bsky.social and collaborators showed now that microdialysis is a suitable tool to simulate exudation.
Read more in BMC Microbiology:
doi.org/10.1186/s128...
Reverse microdialysis of sucrose stimulates soil fungal and bacterial growth at the microscale - BMC Microbiology
Background The rhizosphere is a critical microenvironment that plays key roles in plant nutrient availability, largely due to root interactions with rhizospheric microbes. However, we lack suitable me...
link.springer.com
July 25, 2025 at 10:59 AM
🧪🌾PAPER - How to investigate interactions between root exudation and soil microbial community composition? 🧫
The group of @rootsofthenorth.bsky.social and collaborators showed now that microdialysis is a suitable tool to simulate exudation.
Read more in BMC Microbiology:
doi.org/10.1186/s128...
The group of @rootsofthenorth.bsky.social and collaborators showed now that microdialysis is a suitable tool to simulate exudation.
Read more in BMC Microbiology:
doi.org/10.1186/s128...
btw, my undergrad students wanted to know if anyone had done a quantitative technique to measure dopamine before and after L-DOPA, say like with microdialysis and I couldnt think of a paper if anyone knows one we'd appreciate it!
November 21, 2024 at 11:46 PM
btw, my undergrad students wanted to know if anyone had done a quantitative technique to measure dopamine before and after L-DOPA, say like with microdialysis and I couldnt think of a paper if anyone knows one we'd appreciate it!
Our new paper out!
👉 A step toward dynamic, in-situ bioavailability assessment for precision agriculture and environmental risk evaluation.
#SoilScience #Rhizosphere #Bioavailability #Microdialysis #PlantUptake
link.springer.com/article/10.1...
👉 A step toward dynamic, in-situ bioavailability assessment for precision agriculture and environmental risk evaluation.
#SoilScience #Rhizosphere #Bioavailability #Microdialysis #PlantUptake
link.springer.com/article/10.1...
Soil microdialysis as a tool to simulate rhizosphere dynamics and estimate metal(loid) uptake in radish (Raphanus sativus L.) - Plant and Soil
Background and Aims Soil microdialysis is an emerging in-situ sampling technique that mimics bidirectional exchanges of chemicals in the rhizosphere; however, its effectiveness in predicting plant upt...
link.springer.com
October 17, 2025 at 2:01 AM
Our new paper out!
👉 A step toward dynamic, in-situ bioavailability assessment for precision agriculture and environmental risk evaluation.
#SoilScience #Rhizosphere #Bioavailability #Microdialysis #PlantUptake
link.springer.com/article/10.1...
👉 A step toward dynamic, in-situ bioavailability assessment for precision agriculture and environmental risk evaluation.
#SoilScience #Rhizosphere #Bioavailability #Microdialysis #PlantUptake
link.springer.com/article/10.1...
We have developed a new way of performing in vivo phage display screens by introducing microdialysis catheter into the in vivo screen to capture the macrocyclic homing and tissue penetrating peptides for efficient drug delivery www.life-science-alliance.org/content/8/5/...
@lsajournal.org
@lsajournal.org
February 14, 2026 at 7:46 PM
We have developed a new way of performing in vivo phage display screens by introducing microdialysis catheter into the in vivo screen to capture the macrocyclic homing and tissue penetrating peptides for efficient drug delivery www.life-science-alliance.org/content/8/5/...
@lsajournal.org
@lsajournal.org
4/ 🕒 Historical Context:
Foundational work from Huda Akil and colleagues showed that PAG stimulation produces analgesia blocked by naloxone, highlighting opioid signaling in pain modulation
Until recently, studying opioid release was limited by slow microdialysis (~10–12 min resolution)
Foundational work from Huda Akil and colleagues showed that PAG stimulation produces analgesia blocked by naloxone, highlighting opioid signaling in pain modulation
Until recently, studying opioid release was limited by slow microdialysis (~10–12 min resolution)
January 4, 2025 at 5:27 PM
4/ 🕒 Historical Context:
Foundational work from Huda Akil and colleagues showed that PAG stimulation produces analgesia blocked by naloxone, highlighting opioid signaling in pain modulation
Until recently, studying opioid release was limited by slow microdialysis (~10–12 min resolution)
Foundational work from Huda Akil and colleagues showed that PAG stimulation produces analgesia blocked by naloxone, highlighting opioid signaling in pain modulation
Until recently, studying opioid release was limited by slow microdialysis (~10–12 min resolution)
Paper on the challenges of hydrophobic drugs in cerebral microdialysis accepted to #CTSJournal, #ASCPTJournalFamily Based on own data + intensive literature review, we developed a decision tree to guide future studies in testing unspecific binding prior to microdialysis: doi.org/10.1111/cts....
Experimental Insights and Recommendations for Successfully Performing Cerebral Microdialysis With Hydrophobic Drug Candidates
Cerebral microdialysis in rodents represents a robust and versatile technique for quantifying the pharmacologically relevant unbound fraction of drugs in the brain. When this unbound fraction is simu...
doi.org
May 4, 2025 at 6:15 PM
Paper on the challenges of hydrophobic drugs in cerebral microdialysis accepted to #CTSJournal, #ASCPTJournalFamily Based on own data + intensive literature review, we developed a decision tree to guide future studies in testing unspecific binding prior to microdialysis: doi.org/10.1111/cts....
I love this is the food given in all the early Di Chiara microdialysis papers.
April 11, 2025 at 6:09 PM
I love this is the food given in all the early Di Chiara microdialysis papers.
Using reverse microdialysis in undisturbed soils we show that, compared to sugars, organic acids were i) removed quicker from the exudation spot, ii) preferentially respired by microbes and iii) led to the production of metabolic byproducts. 2/6
February 27, 2025 at 7:22 PM
Using reverse microdialysis in undisturbed soils we show that, compared to sugars, organic acids were i) removed quicker from the exudation spot, ii) preferentially respired by microbes and iii) led to the production of metabolic byproducts. 2/6
This is an excellent society that I joined almost 20 years ago. The meetings are small and collegial, with highly approachable attendees and lively discussions. You’ll hear the latest advances in measuring molecular signaling in the brains using optical, electrochemical, and microdialysis tools.
February 3, 2026 at 8:47 AM
This is an excellent society that I joined almost 20 years ago. The meetings are small and collegial, with highly approachable attendees and lively discussions. You’ll hear the latest advances in measuring molecular signaling in the brains using optical, electrochemical, and microdialysis tools.
Thanks to @stefangorka.bsky.social, Alex König, Erich Inselsbacher and others. See also our previous studies on reverse microdialysis to explore microbial dynamics at soil exudation hotspots: doi.org/10.1016/j.so... and doi.org/10.1016/j.so... . Funding: Austrian Science Fund @fwf-at.bsky.social 6/6
Redirecting
doi.org
February 27, 2025 at 7:22 PM
Thanks to @stefangorka.bsky.social, Alex König, Erich Inselsbacher and others. See also our previous studies on reverse microdialysis to explore microbial dynamics at soil exudation hotspots: doi.org/10.1016/j.so... and doi.org/10.1016/j.so... . Funding: Austrian Science Fund @fwf-at.bsky.social 6/6
(2/2) While we rested our (speculative) conclusion on the observation of fermentation products after a pulse of simulated root exudation and estimated O2 depletion from CO2 emissions, this new paper now proved it using O2 sensors in combination with reverse Microdialysis. Really interesting read!
September 13, 2025 at 3:31 PM
(2/2) While we rested our (speculative) conclusion on the observation of fermentation products after a pulse of simulated root exudation and estimated O2 depletion from CO2 emissions, this new paper now proved it using O2 sensors in combination with reverse Microdialysis. Really interesting read!
Congrats to Camille Gylling Hviid on the first paper from her Industrial PhD 🎉 We paired EEG/EMG sleep scoring + hypothalamic histamine microdialysis across wake/sleep drugs and found histamine–wake coupling at baseline can decouple under drug drive. 👏 #SleepResearch #Neuroscience #industrialPhD
Pharmacological modulation of wakefulness and extracellular hypothalamic histamine release in adult male mice using TAK-925, modafinil, pitolisant, MK-8133 and Lu AF11167
Histamine is a key regulator of wake and arousal, however its role in pharmacological modulation of wake is largely unknown. Specifically, whether his…
www.sciencedirect.com
February 10, 2026 at 6:06 PM
Congrats to Camille Gylling Hviid on the first paper from her Industrial PhD 🎉 We paired EEG/EMG sleep scoring + hypothalamic histamine microdialysis across wake/sleep drugs and found histamine–wake coupling at baseline can decouple under drug drive. 👏 #SleepResearch #Neuroscience #industrialPhD
I volunteered for #medicalresearch. You know, while science is still legal. This is microdialysis to study the long-term effects of #pre-eclampsia.
February 10, 2025 at 3:45 PM
I volunteered for #medicalresearch. You know, while science is still legal. This is microdialysis to study the long-term effects of #pre-eclampsia.
....that shows that clonidine decreases DA via an alpha2-AR mechanism (using microdialysis) www.sciencedirect.com/science/arti...
Clonidine Reduces Dopamine and Increases GABA in the Nucleus Accumbens: An In Vivo Microdialysis Study
The effects of clonidine, an α2 adrenoceptor agonist, on extracellular concentrations of dopamine and γ-aminobutyric acid (GABA) in the nucleus accumb…
www.sciencedirect.com
November 19, 2024 at 12:37 AM
....that shows that clonidine decreases DA via an alpha2-AR mechanism (using microdialysis) www.sciencedirect.com/science/arti...
A combination of in vivo phage display and microdialysis identifies homing peptides capable of cell and tissue penetration https://buff.ly/3QAjRFX
February 12, 2025 at 6:41 PM
A combination of in vivo phage display and microdialysis identifies homing peptides capable of cell and tissue penetration https://buff.ly/3QAjRFX
🚨 New paper alert! We combined high frequency automated microdialysis with mathematical modelling to understand dynamic HPA axis responses to heart surgery in children.
Dynamic adrenal response of children to cardiac surgery and cardiac catheterisation academic.oup.com/jcem/article...
Dynamic adrenal response of children to cardiac surgery and cardiac catheterisation academic.oup.com/jcem/article...
The dynamic adrenal response of children to cardiac surgery and cardiac catheterisation
AbstractContext. The hypothalamic-pituitary-adrenal (HPA) axis is the key homeostatic system regulating the response to surgical stress. Imbalances in HPA
academic.oup.com
May 19, 2026 at 10:18 AM
🚨 New paper alert! We combined high frequency automated microdialysis with mathematical modelling to understand dynamic HPA axis responses to heart surgery in children.
Dynamic adrenal response of children to cardiac surgery and cardiac catheterisation academic.oup.com/jcem/article...
Dynamic adrenal response of children to cardiac surgery and cardiac catheterisation academic.oup.com/jcem/article...
Microdialysis folk seeing this thread.
a man is sitting in a chair holding a bottle of beer and a cup of coffee .
Alt: a man is sitting in a chair holding a bottle of beer and a cup of coffee .
media.tenor.com
January 28, 2026 at 10:29 PM
Microdialysis folk seeing this thread.
We published the potential future way of performing in vivo phage display screens by introducing microdialysis catheters into the in vivo screen to capture the homing and tissue penetrating phages clones www.life-science-alliance.org/content/8/5/...
Screening of homing and tissue-penetrating peptides by microdialysis and in vivo phage display
In vivo phage display is a method used for identification of organ- or disease-specific vascular homing peptides for targeted delivery of pharmaceutics. It is agnostic as to the nature and identity of...
www.life-science-alliance.org
December 25, 2025 at 12:23 PM
We published the potential future way of performing in vivo phage display screens by introducing microdialysis catheters into the in vivo screen to capture the homing and tissue penetrating phages clones www.life-science-alliance.org/content/8/5/...
in vivo, phage display combined with microdialysis can be used for the discovery of vascular homing peptides capable of extravasation and tissue penetration in the target organ https://buff.ly/3QAjRFX
February 19, 2025 at 4:43 PM
in vivo, phage display combined with microdialysis can be used for the discovery of vascular homing peptides capable of extravasation and tissue penetration in the target organ https://buff.ly/3QAjRFX
Okay last one, where we showed “High-resolution daily profiles of tissue adrenal steroids by portable automated collection”, which was the first ever characterisation of 24hr steroid hormones in ambulatory humans. www.science.org/doi/abs/10.1... (1/4)
High-resolution daily profiles of tissue adrenal steroids by portable automated collection
A wearable microdialysis device allows LC-MS/MS analysis to quantify adrenal steroid hormone variability over 24 hours in healthy ambulatory adults.
www.science.org
November 30, 2024 at 12:01 PM
Okay last one, where we showed “High-resolution daily profiles of tissue adrenal steroids by portable automated collection”, which was the first ever characterisation of 24hr steroid hormones in ambulatory humans. www.science.org/doi/abs/10.1... (1/4)