Read the full paper: MicroNucML enables machine learning-based micronuclei segmentation and micronuclei-nuclei association

Wang et al. introduce MicroNucML, an open-source workflow for automated micronuclei segmentation that combines deep learning with nuclei assignment to enable scalable studies of genome instability and DNA damage responses.

Lebrec et al. present a FRET-based cGAS reporter and show that cGAS activation by genotoxic stress is rare and uncoupled from micronuclei. The study implicates R-loop structures and subtypes of chroma...

Lebrec et al. present a FRET-based cGAS reporter and show that cGAS activation by genotoxic stress is rare and uncoupled from micronuclei. The study implicates R-loop structures and subtypes of chroma...

Researchers at the University of Tsukuba have identified small nuclear fragments known as micronuclei while studying neurons in aged mice. They demonstrated that microglia—the brain's resident immune cells—take up these micronuclei, leading to changes in microglial morphology and gene expression associated with inflammation and vascular function. The research is published in the journal Frontiers in Aging Neuroscience.

A 2026 Scientific Reports cross-sectional study measured ambient radiofrequency exposure at eight primary schools located at varying distances from mobile phone base stations and sampled buccal mucosa...

The mammalian genome is safeguarded within the confines of the interphase nucleus. However, genomic instability can trigger the mislocalization of nuclear DNA to the cytoplasm within micronuclei or as...

Researchers in Japan are searching for novel approaches of treating cancer which could overcome the limitations of current therapies.