#modulators
@kilohearts.com i did not know there was a limit on modulators and modulations in snap heap before but i do now
November 16, 2024 at 1:37 AM
Must read!
Intracellular GPCR modulators enable precision pharmacology
www.nature.com/articles/s44...
Intracellular GPCR modulators enable precision pharmacology - npj Drug Discovery
npj Drug Discovery - Intracellular GPCR modulators enable precision pharmacology
www.nature.com
May 12, 2025 at 7:27 PM
Wigs are recession proof. Voice modulators are recession proof.
August 21, 2023 at 11:42 PM
Satan loves ring modulators
September 24, 2026 at 4:14 PM
Bespoke cytokine modulators
May 2, 2025 at 4:10 PM
Do brain circuits really sit in a 'soup' of neuromodulators? Are neurons like soggy bits of bread soaked in signaling factors? Is the whole brain just squelching around in one big pool of warm modulators?
May 13, 2026 at 3:57 PM
Using EQ+ on some processed noise in the grid, and using Bitwig's Audio Sidechain modulators with the incoming signal to move some peaks to synthesize some wind
February 8, 2026 at 12:06 AM
Metallodrugs: From mere cytotoxic agents to immune modulators and checkpoint inhibitors

doi.org/10.1016/j.cc...
March 1, 2025 at 5:56 AM
Strapped into the device, head flanked by neural modulators that maximize neural plasticity. Spirals and mind melting audio bombarding your senses, carving a new purpose onto your brain. Once it's done, it'll cap off by setting your plasticity to near zero, cementing the new pathways permanently~
April 23, 2026 at 10:39 PM
11/ Immunotherapies: Restoring effective immune function with therapies like cytokine treatments or immune modulators could improve reservoir clearance.
February 11, 2025 at 2:27 PM
cisgender girlboss bottom surgery selective estrogen receptor modulators 💅
Find the 5 words from your birth year that perfectly describe YOUR vibe ⬇️
www.merriam-webster.com/time-traveler/
August 2, 2026 at 1:01 AM
Transient Shaping Rack using a selection of third party plugins and modulators as mini scopes in #bitwig
#sounddesign #musicprodsky #audiosky #edmsky
January 5, 2025 at 1:48 PM
🧬 Interesting...

A new study has uncovered an unexpected feature of human DNA linked to gene activity and the physical organization of DNA.

Human nuclear ribomes reveal DNA-embedded ribonucleotides as epigenetic modulators of transcription-associated DNA supercoiling🏺🧪
www.cell.com/cell/abstrac...
September 24, 2026 at 6:00 PM
This paper provides mechanistic and clinical evidence that COVID mRNA vaccines can act as potent immune modulators, transiently enhancing anti-tumor immunity and improving immune check point blockade efficacy in some cancers.
October 25, 2025 at 1:42 PM
low dose estradiol or the use of Selective Estrogen Receptor Modulators (SERMs) can still have demasculinizing effects with a significantly lower chance of causing breast growth.
December 21, 2024 at 6:22 PM
....Instead of teaching students to become the active producers of meaning, analysis, and arguments, students learn to become the evaluators, modulators, and improvers of synthetic output.»
3/
May 19, 2025 at 5:11 AM
Discovering genetic modulators of the protein homeostasis system through multilevel analysis

Really interesting paper here on proteostasis and genetic modulators.

academic.oup.com/pnasnexus/ar...
Discovering genetic modulators of the protein homeostasis system through multilevel analysis
Abstract. Every protein progresses through a natural lifecycle from birth to maturation to death; this process is coordinated by the protein homeostasis sy
academic.oup.com
January 13, 2025 at 1:48 PM
Can we design allosteric modulators that change a GPCR's preferred G protein? Yes!💥

BAMs at the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.

The lab's 1st preprint! Check it out! 🧪💊🧠🟦https://doi.org/10.1101/2024.11.20.624209
🧵👇
Design of allosteric modulators that change GPCR G protein subtype selectivity
G protein-coupled receptors (GPCRs), the largest family of drug targets, can signal through 16 subtypes of Gα proteins. Biased compounds that selectively activate therapy-relevant pathways promise to ...
doi.org
November 22, 2024 at 4:09 PM
Now online in Cancer Discovery @aacrjournals.bsky.social: Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression - by Daniel Azorín, Dirk Hoffmann, @winklerlab.bsky.social, and colleagues doi.org/10.1158/2159...
October 14, 2025 at 12:00 PM
FM Synthesis Explained with Memes : AudioPilz separates the modulators from the operators
AudioPilz separates the modulators from the operators
FM Synthesis Explained with Memes : AudioPilz separates the modulators from the operators
sonicstate.com
October 13, 2025 at 8:21 AM
We don't really talk about how many masc creators use voice modulators to deepen their voices. It's a weird phenomenon.
February 25, 2026 at 1:10 AM
A diagnosis of cystic fibrosis no longer means you are guaranteed to die in your 20s, due to advances in drug therapy like CFTR Modulators
July 14, 2026 at 6:18 AM
Now online - the Review "Structured protein domains enter the spotlight: modulators of #biomolecularcondensate form and function" from Nathaniel Hess and @jerelleaj.bsky.social.

#PhaseSeparation #ProteinProteinInteraction #Oligomerization #ProteinRNAInteraction

authors.elsevier.com/sd/article/S...
January 23, 2025 at 3:07 PM
I think they're called serms (selective estrogen receptor modulators)
May 6, 2025 at 4:04 AM