ICYMI: Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis @natcomms.nature.com
Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis
Nature Communications, Published online: 29 September 2026; doi:10.1038/s41467-026-77654-2Here, the authors show that neuropeptide Y drives stress-induced osteoporosis by promoting bone marrow adipocyte senescence and impairing bone formation. Pulsed electromagnetic field treatment reverses this via sensory nerve-derived SEMA3A, which suppresses neuropeptide Y through a local circuit.
dlvr.it
September 30, 2026 at 6:29 PM
ICYMI: Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis @natcomms.nature.com
This webinar will help attendees to gain more awareness on Osteogenesis Imperfecta and the impact on oral health and overall dental needs for the dental professions. This includes treatment adaptation and treatment modalities required for delivery of dental care.
Learn mor... https://bit.ly/46yTiZI
Learn mor... https://bit.ly/46yTiZI
September 30, 2026 at 11:00 AM
This webinar will help attendees to gain more awareness on Osteogenesis Imperfecta and the impact on oral health and overall dental needs for the dental professions. This includes treatment adaptation and treatment modalities required for delivery of dental care.
Learn mor... https://bit.ly/46yTiZI
Learn mor... https://bit.ly/46yTiZI
RRID:AB_2082037 from @proteintech.bsky.social was used by authors in their Stem Cell Reports paper. Thanks for making your methods matter! #OpenResearch #ReproducibleResearch #OpenScience
Diminished RELB impairs osteogenesis in mature periodontal ligament stem cells
Read the full paper: Diminished RELB impairs osteogenesis in mature periodontal ligament stem cells
doi.org
September 30, 2026 at 7:00 AM
RRID:AB_2082037 from @proteintech.bsky.social was used by authors in their Stem Cell Reports paper. Thanks for making your methods matter! #OpenResearch #ReproducibleResearch #OpenScience
Dose matters: haploinsufficiency in osteogenesis imperfecta. A Sclocco et al. Nature Rev Endocrinol 27 Jul 2026 shorturl.at/Ao3LR ... defining knowledge gaps that future investigations of this disease should aim to address
September 30, 2026 at 6:57 AM
Dose matters: haploinsufficiency in osteogenesis imperfecta. A Sclocco et al. Nature Rev Endocrinol 27 Jul 2026 shorturl.at/Ao3LR ... defining knowledge gaps that future investigations of this disease should aim to address
Jay Thomas Maneul wants his new character on the PBS series “Donkey Hodie” to be the “Mouse” that roared. Manuel – who has built a career breaking barriers while living with Osteogenesis Imperfecta Type 3 and Autism – is providing the voice for Jeff Mouse.
Jay Thomas Manuel makes big splash with Jeff Mouse
BAKERSFIELD, Calif. (KGET) — Jay Thomas Maneul wants his new character on the PBS series “Donkey Hodie” to be the “Mouse” that roared. Manuel – who has built a career breaking barriers while …
www.kget.com
September 29, 2026 at 9:32 PM
Jay Thomas Maneul wants his new character on the PBS series “Donkey Hodie” to be the “Mouse” that roared. Manuel – who has built a career breaking barriers while living with Osteogenesis Imperfecta Type 3 and Autism – is providing the voice for Jeff Mouse.
Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis @natcomms.nature.com
Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis
Nature Communications, Published online: 29 September 2026; doi:10.1038/s41467-026-77654-2Here, the authors show that neuropeptide Y drives stress-induced osteoporosis by promoting bone marrow adipocyte senescence and impairing bone formation. Pulsed electromagnetic field treatment reverses this via sensory nerve-derived SEMA3A, which suppresses neuropeptide Y through a local circuit.
dlvr.it
September 29, 2026 at 11:29 AM
Pulsed electromagnetic fields activate a peripheral interoceptive pathway to suppress sympathetic Npy for osteogenesis @natcomms.nature.com
Effects of Low Magnitude Vibration on Mesenchymal Stem Cell Osteogenic Potential and Phenotype. VV Maldonado et al. Biochimie 2026 Sep 23 shorturl.at/3wuuo …PIEZO1 channel is important for LMV-induced osteogenesis in BM-MSCs
September 28, 2026 at 7:39 AM
Effects of Low Magnitude Vibration on Mesenchymal Stem Cell Osteogenic Potential and Phenotype. VV Maldonado et al. Biochimie 2026 Sep 23 shorturl.at/3wuuo …PIEZO1 channel is important for LMV-induced osteogenesis in BM-MSCs
Michel Petrucciani - September Second
www.youtube.com/channel/UC2p...
www.youtube.com/channel/UC2p...
Michel Petrucciani - Topic
Michel Petrucciani was a French jazz pianist. From birth he had osteogenesis imperfecta, a genetic disease that causes brittle bones and, in his case, short stature. Despite his health condition and…
www.youtube.com
September 26, 2026 at 9:12 PM
Michel Petrucciani - September Second
www.youtube.com/channel/UC2p...
www.youtube.com/channel/UC2p...
Friend's baby also had anencephaly. Baby lacked a skull and internal organs were outside the body. Another friend's fetus had osteogenesis imperfecta and baby's bones were mush. Families were advised that both babies couldn't survive outside the womb and the mothers may die if they carried to term.
September 25, 2026 at 12:28 AM
Friend's baby also had anencephaly. Baby lacked a skull and internal organs were outside the body. Another friend's fetus had osteogenesis imperfecta and baby's bones were mush. Families were advised that both babies couldn't survive outside the womb and the mothers may die if they carried to term.
Targeting GPX4-mediated lipid peroxidation: Bajitianwan ameliorates iron overload-induced osteoporosis by biphasically regulating osteogenesis and osteoclastogenesis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10973997/latest
https://www.researchsquare.com/article/rs-10973997/latest
September 24, 2026 at 4:03 PM
Targeting GPX4-mediated lipid peroxidation: Bajitianwan ameliorates iron overload-induced osteoporosis by biphasically regulating osteogenesis and osteoclastogenesis #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10973997/latest
https://www.researchsquare.com/article/rs-10973997/latest
This webinar will increase awareness on Osteogenesis Imperfecta in relation to dental care and also review the risks associated with dental treatment and the importance of an MDT approach including dentists' role.
Register here: https://bit.ly/46yTiZI
Register here: https://bit.ly/46yTiZI
September 20, 2026 at 2:00 PM
This webinar will increase awareness on Osteogenesis Imperfecta in relation to dental care and also review the risks associated with dental treatment and the importance of an MDT approach including dentists' role.
Register here: https://bit.ly/46yTiZI
Register here: https://bit.ly/46yTiZI
This study identifies SCFJFK as an E3 ligase that mediates #RUNX2 degradation, and a reciprocal RUNX2–JFK feedback loop linking #Proteostasis to #Osteogenesis and the pathogenesis of #CleidocranialDysplasia. @pku1898.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
September 20, 2026 at 1:50 AM
This study identifies SCFJFK as an E3 ligase that mediates #RUNX2 degradation, and a reciprocal RUNX2–JFK feedback loop linking #Proteostasis to #Osteogenesis and the pathogenesis of #CleidocranialDysplasia. @pku1898.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
#STTT #OpenAccess: doi.org/10.1038/s413...
"Osteogenesis Imperfecta" by Medical Etymology from "Concepts of Medical Terminology" in 2026. #NowPlaying
September 19, 2026 at 5:49 AM
"Osteogenesis Imperfecta" by Medical Etymology from "Concepts of Medical Terminology" in 2026. #NowPlaying
Decoding bone loss requires uncovering estrogen‑linked cell death.
This study identifies an estrogen/SIRT5/FDX1 axis regulating cuproptosis, with SIRT5 rescuing #osteogenesis and offering therapeutic potential for #osteoporosis.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies an estrogen/SIRT5/FDX1 axis regulating cuproptosis, with SIRT5 rescuing #osteogenesis and offering therapeutic potential for #osteoporosis.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
September 18, 2026 at 3:19 PM
Decoding bone loss requires uncovering estrogen‑linked cell death.
This study identifies an estrogen/SIRT5/FDX1 axis regulating cuproptosis, with SIRT5 rescuing #osteogenesis and offering therapeutic potential for #osteoporosis.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
This study identifies an estrogen/SIRT5/FDX1 axis regulating cuproptosis, with SIRT5 rescuing #osteogenesis and offering therapeutic potential for #osteoporosis.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
Inhibition of the PRC2, through targeting the core component embryonic ectoderm development (EED), is a novel strategy to enhance osteogenesis and improve bone properties in a murine model of osteogenesis imperfecta. MEC Jeldres et al. JBMR Plus 22 Aug 2026 shorturl.at/qhO1B
September 16, 2026 at 7:52 AM
Inhibition of the PRC2, through targeting the core component embryonic ectoderm development (EED), is a novel strategy to enhance osteogenesis and improve bone properties in a murine model of osteogenesis imperfecta. MEC Jeldres et al. JBMR Plus 22 Aug 2026 shorturl.at/qhO1B
Effectiveness and limitations of anti-sclerostin therapy in osteogenesis imperfecta: A systematic review. Zhiming Wu et al. Bone 7 Sep 2026 shorturl.at/zm7aO … currently no consensus on the effects of anti-sclerostin therapy on bone quality in OI
September 16, 2026 at 7:07 AM
Effectiveness and limitations of anti-sclerostin therapy in osteogenesis imperfecta: A systematic review. Zhiming Wu et al. Bone 7 Sep 2026 shorturl.at/zm7aO … currently no consensus on the effects of anti-sclerostin therapy on bone quality in OI
Open Access UCL Research: Parent and professional experiences of a clinical trial of prenatal and postnatal stem cell therapy for severe osteogenesis imperfecta
discovery.ucl.ac.uk/id/eprint/10...
discovery.ucl.ac.uk/id/eprint/10...
September 15, 2026 at 8:22 AM
Open Access UCL Research: Parent and professional experiences of a clinical trial of prenatal and postnatal stem cell therapy for severe osteogenesis imperfecta
discovery.ucl.ac.uk/id/eprint/10...
discovery.ucl.ac.uk/id/eprint/10...
More #mineral does not always make #bone stronger. In mice with high bone mass #osteogenesis imperfecta, abnormal collagen processing disrupted the bone matrix, producing thinner, poorly aligned mineral particles and bones that were highly mineralized but extremely brittle.👇
@brjournal.bsky.social
@brjournal.bsky.social
September 11, 2026 at 6:10 AM
More #mineral does not always make #bone stronger. In mice with high bone mass #osteogenesis imperfecta, abnormal collagen processing disrupted the bone matrix, producing thinner, poorly aligned mineral particles and bones that were highly mineralized but extremely brittle.👇
@brjournal.bsky.social
@brjournal.bsky.social
Learn how betaine protects bone.
This study shows betaine blocks #ferroptosis, restores osteogenesis via the ABCG1–HMOX1 axis, and emerges as a promising therapy for #RenalOsteodystrophy. #ChronicKidneyDisease
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study shows betaine blocks #ferroptosis, restores osteogenesis via the ABCG1–HMOX1 axis, and emerges as a promising therapy for #RenalOsteodystrophy. #ChronicKidneyDisease
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
September 10, 2026 at 4:20 PM
Learn how betaine protects bone.
This study shows betaine blocks #ferroptosis, restores osteogenesis via the ABCG1–HMOX1 axis, and emerges as a promising therapy for #RenalOsteodystrophy. #ChronicKidneyDisease
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
This study shows betaine blocks #ferroptosis, restores osteogenesis via the ABCG1–HMOX1 axis, and emerges as a promising therapy for #RenalOsteodystrophy. #ChronicKidneyDisease
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
A paper using RRID:AB_2880691 from @proteintech.bsky.social was just published in Stem Cell Reports. We value the author's support of reproducibility. #OpenScience #STMpublishing #reproducibility
SIRT1 promotes endothelial activity and osteogenesis in vitro and ameliorates age-related skeletal regeneration defects in vivo
Read the full paper: SIRT1 promotes endothelial activity and osteogenesis in vitro and ameliorates age-related skeletal regeneration defects in vivo
doi.org
September 9, 2026 at 7:00 AM
A paper using RRID:AB_2880691 from @proteintech.bsky.social was just published in Stem Cell Reports. We value the author's support of reproducibility. #OpenScience #STMpublishing #reproducibility
it's pissed me off bc the shit take haver then compared her deceased friend who had osteogenesis imperfecta (which I have, and she spelt wrong) spending his life advocating for our rare disease and raising awareness, to an old woman not telling the world she has cancer
September 5, 2026 at 1:50 PM
it's pissed me off bc the shit take haver then compared her deceased friend who had osteogenesis imperfecta (which I have, and she spelt wrong) spending his life advocating for our rare disease and raising awareness, to an old woman not telling the world she has cancer
Inhibition of EED enhances osteogenic differentiation and bone formation: a potential therapeutic epigenetic strategy for osteogenesis imperfecta. MEC Jeldres et al. JBMR Plus 22 Aug 2026 shorturl.at/UcxG4 ...fine experiments in OI mouse models and patient cells
September 3, 2026 at 7:02 AM
Inhibition of EED enhances osteogenic differentiation and bone formation: a potential therapeutic epigenetic strategy for osteogenesis imperfecta. MEC Jeldres et al. JBMR Plus 22 Aug 2026 shorturl.at/UcxG4 ...fine experiments in OI mouse models and patient cells
ich lebe mit Osteogenesis imperfecta III ich will weder Mitleid noch aufrechnen wer jetzt im Moment gerade schlimmer dran ist, ich war sogar auf der in Erfurt stattgefunden 15000 Socken Aktion und kam mit Betroffenen von "euch" ins Gespräch, wir sollten alle zusammen halten,gerade in diesen Zeiten
September 2, 2026 at 2:35 PM
ich lebe mit Osteogenesis imperfecta III ich will weder Mitleid noch aufrechnen wer jetzt im Moment gerade schlimmer dran ist, ich war sogar auf der in Erfurt stattgefunden 15000 Socken Aktion und kam mit Betroffenen von "euch" ins Gespräch, wir sollten alle zusammen halten,gerade in diesen Zeiten
Kirin Naidu, Zachary Zapatero, David P Perrault, Isabel Ryan, Dillan F Villavisanis, Santiago Lopez-Becerra, Maura R Guyler, Sameer Shakir, Jordan W Swanson, Scott P Bartlett, and Jesse A Taylor
Dissolving Doubts: Resorbable Fixation in Posterior Vault Distraction Osteogenesis
Posterior cranial vault distraction osteogenesis (PVDO) traditionally requires titanium screw fixation of metallic distractor footplates. Cho and colleagues recently described an off-label application of the Synthes RapidSorb Injectable Polymer System for footplate fixation in PVDO, reporting reduced distractor removal operative time in an initial single-institution series. This study expands that cohort and further evaluates operative outcomes across a multisurgeon institutional experience....
www.ovid.com
September 1, 2026 at 12:00 AM
Kirin Naidu, Zachary Zapatero, David P Perrault, Isabel Ryan, Dillan F Villavisanis, Santiago Lopez-Becerra, Maura R Guyler, Sameer Shakir, Jordan W Swanson, Scott P Bartlett, and Jesse A Taylor