Integrated Proteogenomic Characterization of Glioblastoma Evolution: Overcoming Barriers to Develop Personalized Treatment Strategies dailynews.ascopubs.org/do/integrate...
March 20, 2025 at 1:34 PM
Integrated Proteogenomic Characterization of Glioblastoma Evolution: Overcoming Barriers to Develop Personalized Treatment Strategies dailynews.ascopubs.org/do/integrate...
Yes, and they were working within Proteogenomic Research, which would target specific Cancer cells with precision medicine to limit damage to patients and contain the spread.
But, MAHA happened
But, MAHA happened
November 2, 2025 at 5:10 PM
Yes, and they were working within Proteogenomic Research, which would target specific Cancer cells with precision medicine to limit damage to patients and contain the spread.
But, MAHA happened
But, MAHA happened
With Syed Haider we show that like BRCAness, phenocopies of Rb genomic defects (RBness) are common and in cancer and predict genetic dependencies. Work from @icr.ac.uk funded by @breastcancernow.bsky.social @cancerresearchuk.org www.science.org/doi/10.1126/...
Proteogenomic discovery of RB1-defective phenocopy in cancer predicts disease outcome, response to treatment, and therapeutic targets
A proteogenomic approach identifies a class of cancers (RBness) that phenocopies RB1-defective tumors.
www.science.org
March 26, 2025 at 6:47 PM
With Syed Haider we show that like BRCAness, phenocopies of Rb genomic defects (RBness) are common and in cancer and predict genetic dependencies. Work from @icr.ac.uk funded by @breastcancernow.bsky.social @cancerresearchuk.org www.science.org/doi/10.1126/...
Largest proteogenomic study (n=78,664) reveals >24,000 protein QTLs linked to 1,116 proteins, uncovering pathways and genetic effects on disease mechanisms. PMID:42097137, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00385-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00385-5
No description available
www.cell.com
September 22, 2026 at 7:00 PM
Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals cancer adaptive strategies for alleviating aneuploidy consequences – including increased expression of DNA replication & repair factors & of FOXM1 targets
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
February 10, 2025 at 12:08 PM
Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals cancer adaptive strategies for alleviating aneuploidy consequences – including increased expression of DNA replication & repair factors & of FOXM1 targets
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Scientists have created PLAMseq – a new method to enable proteogenomic characterization of genome proteins and their interactions in a single workflow >>> www.biotechniques.com/proteomics/i... 🧪
Introducing PLAMseq: new sequencing method transforms proteogenomic characterization
A new alternative to CHIPseq performs proteomics and genomics in the same workflow.
www.biotechniques.com
December 16, 2025 at 3:41 PM
Scientists have created PLAMseq – a new method to enable proteogenomic characterization of genome proteins and their interactions in a single workflow >>> www.biotechniques.com/proteomics/i... 🧪
A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 26, 2026 at 7:27 PM
A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Now online! Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
A large-scale multi-cohort proteogenomic study identifies genetic loci influencing circulating protein levels, revealing pathways and cell types that regulate the circulating proteome and highlighting disease insights and evidence for potential therapeutic opportunities.
dlvr.it
May 6, 2026 at 3:00 PM
Now online! Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data go.nature.com/4eEVVvo
rdcu.be/eCbk3
rdcu.be/eCbk3
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy - Nature Biotechnology
The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data.
go.nature.com
August 28, 2025 at 2:37 AM
The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data go.nature.com/4eEVVvo
rdcu.be/eCbk3
rdcu.be/eCbk3
Right. For my 2016 ccRCC proteogenomic paper I mimicked this Zhang et al. 2014 figure.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
January 11, 2025 at 2:02 PM
Right. For my 2016 ccRCC proteogenomic paper I mimicked this Zhang et al. 2014 figure.
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
and large-scale proteogenomic insights into disease mechanisms
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome
A large-scale multi-cohort proteogenomic study identifies genetic loci influencing
circulating protein levels, revealing pathways and cell types that regulate the circulating
proteome and highlighting...
www.cell.com
May 28, 2026 at 4:12 PM
and large-scale proteogenomic insights into disease mechanisms
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy - Nature Biotechnology
The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data.
www.nature.com
October 18, 2024 at 7:02 PM
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Online Now: Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups
Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups
In this study, Ji et al. conduct comprehensive proteogenomic characterization of non-functional pancreatic neuroendocrine tumors and develop a three-protein prognostic biomarker to identify high-risk patients for improving disease management. Proteomic-based stratification uncovers four subtypes with distinct molecular characteristics, immune landscape, and clinicopathological features, with implications on precision treatment.
dlvr.it
April 7, 2025 at 11:52 AM
Online Now: Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups
Proud to share our collaborative effort between the Taiwan Cancer Moonshot Program and the NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC), delivering an integrative proteogenomic atlas of lung adenocarcinoma.
Open-access link: authors.elsevier.com/sd/article/S...
Open-access link: authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
August 1, 2025 at 1:49 PM
Proud to share our collaborative effort between the Taiwan Cancer Moonshot Program and the NCI’s Clinical Proteomic Tumor Analysis Consortium (CPTAC), delivering an integrative proteogenomic atlas of lung adenocarcinoma.
Open-access link: authors.elsevier.com/sd/article/S...
Open-access link: authors.elsevier.com/sd/article/S...
Plasma levels of two-thirds of protein targets differ significantly by sex. In contrast, genetic effects on protein targets are remarkably similar across sexes www.nature.com/articles/s41... @natcomms.nature.com
Sex differences in the genetic regulation of the human plasma proteome - Nature Communications
Analysing proteogenomic data from two large cohorts reveals that genetic regulation of the plasma proteome is highly similar between biological sexes, despite large differences in plasma abundance, wi...
www.nature.com
May 13, 2025 at 10:31 AM
Plasma levels of two-thirds of protein targets differ significantly by sex. In contrast, genetic effects on protein targets are remarkably similar across sexes www.nature.com/articles/s41... @natcomms.nature.com
Curious job application letter today, which included:
"I am particularly interested in your recent work on integrated proteogenomic and immunopeptidomic analyses to understand host–pathogen and tumor–immune interactions (e.g., Cell, 2020; Nature Communications, 2020)"
Not my research, not my papers
"I am particularly interested in your recent work on integrated proteogenomic and immunopeptidomic analyses to understand host–pathogen and tumor–immune interactions (e.g., Cell, 2020; Nature Communications, 2020)"
Not my research, not my papers
I Think You Have The Wrong Number Mike GIF
Alt: I Think You Have The Wrong Number Mike GIF
media.tenor.com
January 6, 2026 at 3:27 PM
Curious job application letter today, which included:
"I am particularly interested in your recent work on integrated proteogenomic and immunopeptidomic analyses to understand host–pathogen and tumor–immune interactions (e.g., Cell, 2020; Nature Communications, 2020)"
Not my research, not my papers
"I am particularly interested in your recent work on integrated proteogenomic and immunopeptidomic analyses to understand host–pathogen and tumor–immune interactions (e.g., Cell, 2020; Nature Communications, 2020)"
Not my research, not my papers
Open Access UCL Research: Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease
discovery.ucl.ac.uk/id/eprint/10...
discovery.ucl.ac.uk/id/eprint/10...
Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease
-
UCL Discovery
UCL Discovery is UCL's open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
discovery.ucl.ac.uk
September 24, 2026 at 10:09 AM
Open Access UCL Research: Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease
discovery.ucl.ac.uk/id/eprint/10...
discovery.ucl.ac.uk/id/eprint/10...
Applying a proteogenomic approach for improving genome annotation in Leishmania panamensis using high-resolution mass spectrometry data pubmed.ncbi.nlm.nih.gov/42542199/
August 2, 2026 at 10:32 AM
Applying a proteogenomic approach for improving genome annotation in Leishmania panamensis using high-resolution mass spectrometry data pubmed.ncbi.nlm.nih.gov/42542199/
Proteogenomic approaches for snake venom protein-based drug development: current trends and challenges pubmed.ncbi.nlm.nih.gov/39749538/
January 5, 2025 at 2:34 AM
Proteogenomic approaches for snake venom protein-based drug development: current trends and challenges pubmed.ncbi.nlm.nih.gov/39749538/
Integrated proteogenomic and metabolomic profiling of acute myeloid leukemias to identify molecular subtypes and associated therapy targets www.nature.com/articles/s4...
June 27, 2026 at 2:15 PM
Integrated proteogenomic and metabolomic profiling of acute myeloid leukemias to identify molecular subtypes and associated therapy targets www.nature.com/articles/s4...
Largest proteogenomic study (n=78,664) identifies >24,000 protein QTLs linked to 1,116 proteins, revealing insights into genetic regulation and disease mechanisms. PMID:42097137, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00385-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00385-5
No description available
www.cell.com
August 8, 2026 at 1:00 AM
Online Now: Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer
Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer
Fu et al. present an integrative proteogenomic analysis of a large gallbladder cancer cohort, which uncovers ErbB2/ErbB3 genomic alterations with clinical relevance; identifies MEIS1, ACAT1, and PHGDH as potential therapeutic targets; and establishes immune and multi-omic subtypes that inform prognosis and guide treatment strategies.
dlvr.it
January 9, 2026 at 7:51 PM
Online Now: Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer
Comprehensive #Proteogenomics (pQTL) of human kidneys discerning genetically regulated protein changes in #KidneyFunction and #CardioKidneyMetabolicDisease (CKM) offer targetable mechanism www.nature.com/articles/s41... @ksusztak.bsky.social #TranslationalScience
The proteogenomic landscape of the human kidney and implications for cardio-kidney-metabolic health - Nature Medicine
Based on 337 human kidney and plasma samples, the authors generate the first kidney pQTL dataset and explore novel risk loci that are relevant for cardio-kidney-metabolic health.
www.nature.com
August 14, 2025 at 7:41 PM
Comprehensive #Proteogenomics (pQTL) of human kidneys discerning genetically regulated protein changes in #KidneyFunction and #CardioKidneyMetabolicDisease (CKM) offer targetable mechanism www.nature.com/articles/s41... @ksusztak.bsky.social #TranslationalScience