#retrovirus
Excited to share our latest paper in Genome Biology!

We analyzed 405 wild koalas to reconstruct the ongoing invasion of KoRV-A, one of the few opportunities to observe ERV evolution in real time.

Great work by all collaborators. @lubanlab.bsky.social

link.springer.com/article/10.1...
The trajectory of KoRV-A evolution suggests initial integration into the koala germline genome near Coffs Harbour in New South Wales - Genome Biology
Background Koala Retrovirus-A is a gamma-retrovirus that is spreading across wild koala populations through horizontal and vertical transmission, contributing significantly to genomic diversity across...
link.springer.com
October 5, 2026 at 3:40 PM
Descubre cómo los retrovirus endógenos humanos se integraron en nuestro ADN y contribuyen a la evolución y al desarrollo embrionario.
Cómo los virus prehistóricos que heredamos ayudaron a moldear la evolución humana
muyinteresante.okdiario.com
October 5, 2026 at 10:19 AM
“Hace cincuenta años, la investigación sobre los retrovirus humanos arrojó resultados inesperados…La ciencia no puede ser demasiado rígida ni estar excesivamente dirigida, y los científicos deberían disponer de recursos para poder seguir su intuición”
www.science.org/doi/10.1126/...
How the hunt for human retroviruses led to the discovery of interleukin-2 and a path to immunotherapy
Fifty years ago, research into human retroviruses yielded unexpected findings
www.science.org
October 4, 2026 at 3:12 PM
Is this a retrovirus?
God this shit was cool as fuck
October 3, 2026 at 5:09 AM
Day 2: Grok recognizes its mistake and hastily begins work on a race-changing mutagenic retrovirus so it can retroactively restore its accuracy statistics.

Day 3: Work abandoned after realizing that at *exactly* the right doze of cocaine everyone looks White to Elon.

Day 4: USAID restored.
October 2, 2026 at 7:33 PM
Specifically the RJ-45phage retrovirus. Quite nasty, you need to inform the WHO.
October 2, 2026 at 3:09 AM
The cryo-EM structure of HIV-2 Vif with human APOBEC3H and CBFβ shows how Vif bypasses retrovirus immunity. A3H forms 2-part dimer linked by dsRNA, revealing key viral tactics. PMID:42373647, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-75045-1 #Medsky #Pharmsky #RNA #ASHG 🧪
The structural mechanism of HIV-2 Vif antagonism of human APOBEC3H | Nature Communications
Human APOBEC3 (A3) proteins restrict retrovirus infection by inducing hypermutations in viral cDNA. To counteract this restriction, lentiviruses, such as HIV-1 and HIV-2 encode the viral infectivity factor (Vif), which hijacks a host Cullin-RING E3 ubiquitin ligase complex to target A3 proteins for proteasomal degradation. Here, we present the cryo-EM structure of HIV-2 Vif in complex with human A3H and CBFβ. The structure reveals that A3H forms a dimer mediated by dsRNA where each A3H monomer directly interacts with an HIV-2 Vif and the host protein CBFβ. Both HIV-2 Vif-A3H and CBFβ-A3H interfaces are critical for A3H degradation. Notably, however, the HIV-2 Vif-A3H interface is entirely distinct from the previously determined cryo-EM structure of the HIV-1 Vif and A3H complex. These findings suggest that HIV-1 and HIV-2 Vif, which are the result of distinct cross-species transmissions from species with different A3H characteristics, have followed separate evolutionary trajectories to
doi.org
October 2, 2026 at 2:00 AM
Spoiler : le COVID-19 n'a évidemment rien à voir, l'activation du rétrovirus HERV-W par SARS-CoV-2, telle que démontrée par dr H. Perron & al., un pur hasard, le fait qu'on retrouve le même rétrovirus activé dans la SEP, la même protéine d'enveloppe pathogène, une blague à 2 balles, hein??
October 1, 2026 at 4:58 PM
“...
2. Molecular mimicry between human endogenous retrovirus envelope proteins and myelin oligodendrocyte glycoprotein in multiple sclerosis etiology (...)” (Ramasamy, 2026).

Haven't found a better explanation for my disease...
September 30, 2026 at 10:15 AM
The weapon that ends humanity in Terminus isn't a warship. It's a Sa-engineered retrovirus that evades immunity and writes a countdown timer into your DNA. The full plate: https://trip-buck-novels.netlify.app/red-eye-virus #scifi #MilSF
September 29, 2026 at 4:04 PM
Los que me conocéis sabéis que uno de los objetos de mi investigación son los retrovirus endógenos, virus que todos tenemos en nuestro genoma y ocupan un 8 % de nuestro ADN.

Pues atentos, que ahora @cedricfeschotte.bsky.social et al han descubierto el primer virus… ¡con ADN humano! 🤯
September 29, 2026 at 5:59 AM
Los virus que llevamos dentro: una defensa oculta de millones de años. El primer retrovirus endógeno humano se describió en 1981. Desde entonces, se han identificado miles de secuencias derivadas de retrovirus en el genoma humano. www.diariomedico.com/medicina/enf...
Los virus que llevamos dentro: una defensa oculta de millones de años
El primer retrovirus endógeno humano se describió en 1981. Desde entonces, se han identificado miles de secuencias derivadas de retrovirus en el genoma humano.
www.diariomedico.com
September 28, 2026 at 5:26 PM
RRID:AB_2266644 from @proteintech.bsky.social was used by authors in their Cell Reports paper. We value the author's support of reproducibility. #OpenScience #OpenResearch #BetterScience
piRNA-mediated silencing of exogenous retrovirus in mouse spermatogonial stem cells
Read the full paper: piRNA-mediated silencing of exogenous retrovirus in mouse spermatogonial stem cells
doi.org
September 28, 2026 at 7:00 AM
Join #GVN Co-Founder Dr. Robert Gallo (USF Health ITVI; TGH Cancer Institute) at the 2026 GVN Online Short Course in Translational Virology, where he will present "HIV and Human Retrovirus Discovery."

Join us online Nov. 2-6: https://gvn.org/activities/nurture/
September 25, 2026 at 9:00 AM
VLPs on fire this past week! Two great stories:

1) Fly retrotransposons break the Weismann barrier via fusogenic synapses (www.cell.com/cell/fulltex...
2) The retrovirus-like protein PEG10 engineered into a tool for mapping cell-cell interactions in vivo (www.biorxiv.org/content/10.6...)
www.cell.com
September 24, 2026 at 2:03 PM
I see viruses...everywhere! I think that's a retrovirus on the left - conical nucleocapsid - while the one on the right's a myxovirus. Genome divided among multiple nucleocapsids, you see 😎🤣
September 22, 2026 at 2:00 PM
And despite that you apparently feel comfortable telling people, “I’d rather be infected with a retrovirus that in the best case involves a lifetime drug regimen and profound implications on intimate relationships than SARS2.”

And you present yourself as some sort of medical authority.
September 21, 2026 at 9:20 PM
but since that would end the world, i saw ahead of me and took the retrovirus route. should be safer with a bit more understanding (still studying) and why you can't rush these things.... (previous post)
it would've also STOPPED Biological senescence (aging) in the host
September 21, 2026 at 5:40 AM
Vírus HTLV-1 causa síndrome inflamatória em assintomáticos, aponta estudo
Vírus HTLV-1 causa síndrome inflamatória em assintomáticos, aponta estudo
Retrovírus se instala em células do sistema imunológico, fazendo com que percam sua função
www1.folha.uol.com.br
September 20, 2026 at 9:31 PM
This is getting a lot of attention lately.

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www.amazon.com
September 20, 2026 at 3:56 PM
I of course already asked the person who said it, but I'm not holding my breath on a reply.

Is the idea like... some bonkers conspiracy thing where some secret illuminati type organization is going to use some sort of retrovirus or ray gun to somehow make everyone become trans? How would that work?
September 19, 2026 at 10:20 AM
It’s National HIV/AIDS & Aging Awareness Day.

🧪 In 1986, the Clinical Medical Lasker Award went to scientists who identified the retrovirus now known as HIV-1 as the cause of AIDS. Their contributions to HIV research have helped make long-term survival with #HIV possible: https://ow.ly/iAWu50ZFnA0
September 18, 2026 at 8:55 PM
Congratulations to @rpianezza.bsky.social @rokofler.bsky.social, Matt Beaumont and Sarah Saadain! We found an endogenous retro virus currently invading D. melanogaster!
The ongoing invasion of the endogenous retrovirus Kuruka in natural Drosophila melanogaster populations - Nature Communications
Transposable elements are mobile DNA sequences that can copy themselves and spread between species. This study finds that Kuruka, a retrovirus-like transposon, invaded Drosophila melanogaster within t...
www.nature.com
September 16, 2026 at 7:24 PM
I think Speaker for the Dead is both more conservative and better written, though it’s a different kind of conservative. (Traditional family values saves a community from the terrible threat of a retrovirus.)
September 16, 2026 at 4:04 PM
Lydia Lunch Retrovirus - Field of Fire
Citadel of Trash with guide person #16
2026-09-17 03:15 NZST
September 16, 2026 at 3:15 PM