#sRNAs
🔬 My latest work w/ @immler.bsky.social et al: Env. stress alters sperm sRNAs, linking gene expr. + transposons in #zebrafish offspring. @heredityjournal.bsky.social
🧬 Social stress shapes RNA/TE activity across generations
#Sperm #miRNA #piRNA #Transposons #TEsky @biouea.bsky.social
rdcu.be/eeAwB
Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring
Heredity - Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring
rdcu.be
March 22, 2025 at 2:16 PM
Excited to share our new preprint on an RNA sponge counteracting sibling sRNAs in Caulobacter!
Laura Vogt and @mvelascogomariz.bsky.social used RILseq, RNA biochemistry and great commitment to work out this story!
www.researchsquare.com/article/rs-6...
March 28, 2025 at 8:09 AM
A fungal sRNA silences a host plant transcription factor to promote arbuscular mycorrhizal symbiosis

in @newphyt.bsky.social from Luisa Lanfranco and @ignaciorubiosomoza.bsky.social

nph.onlinelibrary.wiley.com/doi/10.1111/...
A fungal sRNA silences a host plant transcription factor to promote arbuscular mycorrhizal symbiosis
Cross-kingdom RNA interference (ckRNAi) is a mechanism of interspecies communication where small RNAs (sRNAs) are transported from one organism to another; these sRNAs silence target genes in trans .....
nph.onlinelibrary.wiley.com
November 19, 2024 at 11:31 AM
Our keynote speaker Franziska Faber on sRNAs in #Cdiff #sporulation @3cdf.bsky.social #3CdF2026
June 5, 2026 at 7:52 AM
Bacterial small regulatory RNAs | Nature Reviews Microbiology
Bacterial small regulatory RNAs - Nature Reviews Microbiology
In this Review, Papenfort discusses established and emerging aspects of bacterial small RNAs (sRNAs), their molecular mechanisms and regulatory principles, and the global impact of sRNAs on cellular gene expression profiles.
www.nature.com
August 19, 2026 at 10:11 AM
We are thrilled to announce that Prof. Wenbo Ma FRS has been awarded a highly competitive @erc.europa.eu Advanced Grant for her exciting new project sRNA-Defense, which will allow her and her team to uncover new roles for sRNAs in defending plants from pathogens 🧬🌱

www.tsl.ac.uk/news/srna-re...
June 23, 2026 at 11:30 AM
I will be presenting my @camplantsci.bsky.social #postdoc work at the Plant Phys Centennial posters today from 5.30pm to 6.15pm poster number # 000-014! Come chat about tranposon-derived 22nt sRNAs in 🍅! #PlantBio2026 @aspbofficial.bsky.social
July 19, 2026 at 2:00 PM
Latest preprint from our lab describing a new 2-plasmid system to investigate sRNAs-target molecule interactions in A. baumannii.
Development of two compatible plasmids to assess sRNA-mediated post-transcriptional regulation in Acinetobacter baumannii https://www.biorxiv.org/content/10.1101/2025.07.11.664372v1
July 14, 2025 at 7:26 AM
Great scientific discussions and community at the Regulating with RNA in Bacteria and Archaea Meeting in Strasbourg 🇫🇷, presenting NIAID research on B. burgdorferi sRNAs and single-cell RNA-seq #rna
September 10, 2025 at 3:48 PM
Now, @carogutj.bsky.social is presenting her work on arbuscular #mycorrhiza in connection to phosphate starvation response, transcriptional regulation of arbuscule development, and fungal sRNAs acting on plants. 🌱🅿️🧬 #IPB2026
April 23, 2026 at 8:58 AM
New preprint from @westermannlab.bsky.social about a pair of antagonistic #Salmonella sRNAs. Check it out 👇🏻
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT https://www.biorxiv.org/content/10.1101/2025.04.07.647523v1
April 8, 2025 at 5:04 AM
One transcript, two functions: the emerging roles of dual-function RNAs

microLIFE review by @lizmarialuke.bsky.social and Kai Papenfort at @uni-jena.de

academic.oup.com/microlife/ad...
One transcript, two functions: the emerging roles of dual-function RNAs
Abstract. Bacteria use small regulatory RNAs (sRNAs) and small proteins to change gene expression and modulate cellular processes in response to changing e
academic.oup.com
October 27, 2025 at 6:15 PM
Like bacteria, phages use sRNAs to regulate gene expression! Out today in @cp-trendsmicrobiol.bsky.social, @mvelascogomariz.bsky.social and I highlight a recent RIL-seq study from the @saharmelamed.bsky.social lab that looked into posttranscriptional regulation of lambda!

tinyurl.com/lambda-RIL-seq
Unraveling posttranscriptional regulatory networks in phage infection
Phages employ sophisticated transcriptional regulatory networks to optimize replication. Recently, Silverman et al. used RIL-seq (RNA interaction by l…
tinyurl.com
February 26, 2026 at 1:29 PM
Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring

www.nature.com/articles/s41...
Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring - Heredity
Heredity - Environmentally induced variation in sperm sRNAs is linked to gene expression and transposable elements in zebrafish offspring
www.nature.com
April 24, 2025 at 1:34 PM
Nate Johnson asks if small RNAs are the other stuff in the genome

We know sRNAs are important, but how do we find them 🔎, figure out what they do ⚙️, and classify them 📑

Small-RNA seq data may already exist to answer this question

#fungal26
March 21, 2026 at 11:48 PM
The Pseudomonas aeruginosa PrrF sRNAs promote biofilm formation at body temperature https://www.biorxiv.org/content/10.1101/2024.12.11.628005v1
December 12, 2024 at 2:18 AM
New mechanism on gut bacteria colonization found 🤯

Bacterial small RNA makes a big impact for gut colonization: Cell Host & Microbe www.cell.com/cell-host-mi...
Bacterial small RNA makes a big impact for gut colonization
The functions of non-coding small RNAs (sRNAs) within the human microbiome remain largely unexplored. In this Cell Host & Microbe issue, El Mouali et al. identify Segatella RNA colonization factor (Sr...
www.cell.com
November 16, 2024 at 1:34 AM
Very cool new paper from the lab, delving into sRNAs selective degradation enabling TE control! Congrats @oliviacharmant.bsky.social 🎉🎉
November 25, 2024 at 10:06 AM
RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT
Abstract. Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular surv
doi.org
December 27, 2025 at 2:06 PM
🎉 Exciting milestone! Our paper on CiaR-controlled Ccn sRNAs modulating Zn-resistance in S. pneumoniae is out! Congrats to @iuqcb.bsky.social's @mkosterb.bsky.social and Dr. Abigail Garrett. This marks Prof Giedroc's 200th peer-reviewed paper!🔬🧬 #sRNAs #MetalHomeostasis shorturl.at/lMFM3
The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance
Author summary Zn and Mn are essential micronutrients for many bacteria, including Streptococcus pneumoniae. While Zn performs vital structural or catalytic roles in certain proteins, in excess, Zn ca...
shorturl.at
December 4, 2024 at 3:38 PM
RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing url: academic.oup.com/nar/article/...
RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing
Abstract. Most bacterial small regulatory RNAs (sRNAs) modulate gene expression by forming complementary base pairs with target messenger RNAs (mRNAs), dep
academic.oup.com
December 14, 2025 at 4:06 AM
Interesting study shows CsrA forms a dynamic, membraneless compartment with sRNAs, mRNAs & the degradosome in E. coli, flipping its role between activating and repressing virulence. A new layer of RNA-based regulation! #microbiology #RNA #CsrA

www.nature.com/articles/s41...
Formation of a membraneless compartment regulates bacterial virulence - Nature Communications
The RNA-binding protein CsrA switches from upregulation to downregulation of virulence genes in bacteria through unclear mechanisms. Here, the authors show that the switch between promoting and repres...
www.nature.com
April 25, 2025 at 9:10 AM