#stemcell-derived
Disease Modeling in iPSC-Derived Human Bone Marrow Organoids

Work by Ermin Li, Ashley Zheng and Kehan Ren at Stony Brook University and Amy Ji at Columbia University.

#LifeSciences #Reproducibility #StemCell
November 4, 2026 at 2:40 AM
A pilot phase IIa randomized, placebo-controlled, double-blind trial of intravenous human pluripotent adipose-derived stem cells (PASCs) in Parkinson’s disease: The REPOSE study
doi.org/10.1177/0963...
#Parkinson #stemcell
@journals.sagepub.com
October 29, 2026 at 3:22 AM
The maker of sasineprocel, a patient-derived cell therapy, has published its preclinical work in *Cell Stem Cell* as it heads toward Phase 3.

Link as first comment.

#longevity #geroscience #sasineprocel #celltherapy #stemcell
October 2, 2026 at 1:14 PM
🧠 How can #stemcell-derived #extracellularvesicles advance therapies for #neuropsychiatric disorders?
This Review explores their neuroprotective mechanisms, therapeutic potential, and key challenges in clinical translation. 🔬
www.oaepublish.com/articles/evc...
@drwp.bsky.social @jdevos.bsky.social
September 17, 2026 at 2:27 AM
✨ Turning stem cells into stronger EV producers!
New EVCNA research shows that DFO-primed #stemcell-derived #sEVs enhance angiogenesis, support vascularized tissue integration, and promote reparative macrophage polarization. 🧬🩸
👇
www.oaepublish.com/articles/evc...
@fhelmbacher.bsky.social
September 9, 2026 at 2:48 AM
This week's #WednesdayCoffeeTalk: Matthias Hebrok from @tum.de on "Optimizing #stemcell derived beta cells for #diabetes therapy.”

Join us this Wednesday at 1 p.m. - DM us for Zoom info!

www.tum.de/en/news-and-...
Engineered immune cells may be able to tame inflammation
Whether it's type 1 diabetes, other autoimmune diseases or organ transplants – when the immune system gets out of balance, it can be dangerous. Instead of suppressing the entire system as a consequenc...
www.tum.de
June 10, 2025 at 11:17 AM
Photobiomodulation-induced activation of Wnt signaling enhances differentiation of adipose-derived stem cells into tenocytes: Mechanistic insights into regenerative signaling pathways
doi.org/10.1177/0963...
#stemcell #regeneration #signalisart @journals.sagepub.com
August 12, 2026 at 8:16 AM
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling
doi.org/10.1177/0963...
#EV #Stemcell
@journals.sagepub.com
July 16, 2026 at 2:44 AM
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling
doi.org/10.1177/0963...
#stemcell #signaling
@journals.sagepub.com
July 4, 2026 at 9:21 AM
Effects of human embryonic stem cell–derived Schwann cells for nerve regeneration after facial nerve injury
doi.org/10.1177/0963...
#stemcell #schwann #nerve #regeneration
@journals.sagepub.com
March 27, 2026 at 8:22 AM
Impact of Kellgren–Lawrence grade on clinical outcomes following adipose-derived stem cell therapy for #knee #osteoarthritis: A propensity score–matched retrospective cohort study
doi.org/10.1177/0963...
#stemcell
@journals.sagepub.com
January 28, 2026 at 8:23 AM
Adipose-derived stem cells inhibit dendritic cell migration by secreting tumor necrosis factor-α-stimulated gene 6 to improve the allogeneic skin transplantation survival rate in mice
doi.org/10.1177/0963...
#stemcell #skin
November 9, 2025 at 7:33 AM
Neurotropism and direct infiltration of #COVID19
link.springer.com/article/10.1...
🦠 particles in the neurons
rupress.org/jem/article/...
#COVID19 Pandemic - Brain Infection

www.ibroneuroscience.org/article/S030...
October 20, 2023 at 9:41 PM
We are part of the DLD #Health x BAIOSPHERE conference in #Munich—featuring pioneering work on #braincomputer interfaces and human #stemcell-derived #organoids! Looking forward to inspiring discussions on the future of medicine: t1p.de/dld-health26
DLD Conference: Digital-Life-Design
t1p.de
June 10, 2026 at 1:38 PM
Cell therapy approaches are potentially limited by low oxygen supply post transplantation. Multiomic analysis of #StemCell derived #pancreatic islet-like cells in hypoxic culture identifies EDN3 as a gene that preserves beta cell identity and function.
#scRNAseq
Improving cellular fitness of human stem cell-derived islets under hypoxia - Nature Communications
Hypoxia impairs the efficacy of stem cell-derived islet cell therapy, making it a potential barrier for treatment of type 1 diabetes. Wang et al. identify EDN3 as a key factor that preserves β cell id...
www.nature.com
May 24, 2025 at 2:15 PM
Japanese researchers announce results of stem cell (iPS cell-derived neural stem/progenitor cell) transplants into patients with spinal cord injuries. Claim no health problems and 2 of 4 patients showing improved movement #stemcell #stemcells
iPS細胞使った脊髄損傷治療で機能改善 慶応大学などのグループ | NHK
【NHK】慶応大学などのグループは、事故などで脊髄を損傷して体が動かせず感覚もなくなった患者にiPS細胞から作った神経のもとになる…
www3.nhk.or.jp
March 29, 2025 at 1:39 PM
An off-the-shelf #stemcell-derived #dopaminergic progenitor #therapy for #PD showed a favorable 12-month safety profile, with no graft-related adverse events, or tumor formation, though risks were associated with the immunosuppression regimen.
Human embryonic stem cell-derived dopaminergic cells for Parkinson’s disease: a phase 1/2 open-label trial - Nature Medicine
A phase 1/2 trial of an off-the-shelf stem cell-derived dopaminergic progenitor therapy demonstrated a favorable 12-month safety profile, with no graft-related adverse events, dyskinesias or tumor formation, although risks were associated with the immunosuppression regimen.
dlvr.it
July 10, 2026 at 3:09 PM
Weekly reads: robot grant-writing scientist (AI)?, stem cell-derived sperm make a baby, assembloids & sensory paths ipscell.com/2025/04/week... #stemcells #stemcell
Weekly reads: robot scientist, stem cell sperm make a baby, assembloids & sense - The Niche
Professor talks about life as a scientist and recent news in the stem cell and regenerative medicine field including on iPS cells.
ipscell.com
April 13, 2025 at 2:22 PM
Struggling with #silencing of doxycycline-inducible transgenes in human pluripotent #stemcell derived lineages? You're not alone! In my very first #skeetorial I break down our latest paper on potential solutions to this common problem. Read on! 1/10

open-research-europe.ec.europa.eu/articles/4-2...
February 10, 2025 at 11:06 PM
December 11, 2025 at 8:22 AM